Prevalence of CKD and Comorbid Illness in Elderly Patients in the United States: Results From the Kidney Early Evaluation Program (KEEP)

American Journal of Kidney Diseases

Volumn 55, Issue 3 SUPPL. 2, 2010, Pages

  Stevens, Lesley A ^a   Li, Suying ^b   Wang, Changchun ^b   Huang, Cindy ^a   Becker, Bryan N ^c   Bomback, Andrew S ^d   Brown, Wendy Weinstock ^e   Burrows, Nilka Ríos ^f   Jurkovitz, Claudine T ^g   McFarlane, Samy I ^h   Norris, Keith C ⁱ   Shlipak, Michael ^j   Whaley Connell, Adam T ^k   Chen, Shu Cheng ^b   Bakris, George L ^l   McCullough, Peter A ^m  

^a TUFTS MEDICAL CENTER   (United States)

^b MINNEAPOLIS MEDICAL RESEARCH FOUNDATION   (United States)

^c UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^d Columbia University College of Physicians and Surgeons ^*  (United States)

^e JESSE BROWN VA MEDICAL CENTER   (United States)

^f CENTERS FOR DISEASE CONTROL AND PREVENTION   (United States)

^g CHRISTIANA CARE HEALTH SYSTEM   (United States)

^h KINGS COUNTY HOSPITAL CENTER   (United States)

ⁱ UNIVERSITY OF CALIFORNIA   (United States)

^j Veterans Association Medical Center   (United States)

^k University of Missouri   (United States)

^l UNIVERSITY OF CHICAGO   (United States)

^m Divisions of Cardiology   (United States)

more..

Author keywords

Aged; chronic kidney disease; comorbidity

Indexed keywords

AGED; AGING; ANEMIA; ARTICLE; CARDIOVASCULAR DISEASE; CEREBROVASCULAR DISEASE; CHRONIC KIDNEY DISEASE; COMORBIDITY; CONGESTIVE HEART FAILURE; CORONARY ARTERY DISEASE; DIABETES MELLITUS; EARLY DIAGNOSIS; FEMALE; GERIATRIC PATIENT; GLOMERULUS FILTRATION RATE; HEALTH PROGRAM; HEALTH SURVEY; HUMAN; HYPERCHOLESTEROLEMIA; HYPERPARATHYROIDISM; HYPERPHOSPHATEMIA; HYPERTENSION; HYPOCALCEMIA; KIDNEY DISEASE; KIDNEY FUNCTION; MAJOR CLINICAL STUDY; MALE; MEDICARE; NEOPLASM; PERIPHERAL VASCULAR DISEASE; PREVALENCE; RISK FACTOR; UNITED STATES;

AGE FACTORS; AGED; AGED, 80 AND OVER; CARDIOVASCULAR DISEASES; COHORT STUDIES; COMMUNITY HEALTH SERVICES; COMORBIDITY; CROSS-SECTIONAL STUDIES; FEMALE; FOUNDATIONS; HUMANS; KIDNEY FAILURE, CHRONIC; MALE; MASS SCREENING; PREVALENCE; TIME FACTORS; UNITED STATES;

EID: 76749087371     PISSN: 02726386     EISSN: None     Source Type: Journal    
DOI: 10.1053/j.ajkd.2009.09.035     Document Type: Article

References (41)

1. Centers for Disease Control and Prevention. Trends in aging-United States and worldwide. MMWR Morb Mortal Wkly Rep 52 (2003) 101-104 106
2. US Renal Data System. USRDS 2005 Annual Data Report (2005), National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD
3. Coresh J., Selvin E., Stevens L.A., et al. Prevalence of chronic kidney disease in the United States. JAMA 298 (2007) 2038-2047
4. Shlipak M.G., Katz R., Cushman M., et al. Cystatin-C and inflammatory markers in the ambulatory elderly. Am J Med 118 (2005) 1416.e25-1416.e31
5. Sarnak M.J., Katz R., Stehman-Breen C.O., et al. Cystatin C concentration as a risk factor for heart failure in older adults. Ann Intern Med 142 (2005) 497-505
6. Manjunath G., Tighiouart H., Coresh J., et al. Level of kidney function as a risk factor for cardiovascular outcomes in the elderly. Kidney Int 63 (2003) 1121-1129
7. Keith D.S., Nichols G.A., Gullion C.M., Brown J.B., and Smith D.H. Longitudinal follow-up and outcomes among a population with chronic kidney disease in a large managed care organization. Arch Intern Med 164 (2004) 659-663
8. Go A.S., Chertow G.M., Fan D., McCulloch C.E., and Hsu C.Y. Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization. N Engl J Med 351 (2004) 1296-1305
9. Shlipak M.G., Sarnak M.J., Katz R., et al. Cystatin C and the risk of death and cardiovascular events among elderly persons. N Engl J Med 352 (2005) 2049-2060
10. Shlipak M.G., Katz R., Fried L.F., et al. Cystatin-C and mortality in elderly persons with heart failure. J Am Coll Cardiol 45 (2005) 268-271
11. Sarnak M.J., Levey A.S., Schoolwerth A.C., et al. Kidney disease as a risk factor for development of cardiovascular disease: a statement from the American Heart Association Councils on Kidney in Cardiovascular Disease, High Blood Pressure Research, Clinical Cardiology, and Epidemiology and Prevention. Circulation 108 (2003) 2154-2169
12. Stevens L.A., and Levey A.S. Chronic kidney disease in the elderly-how to assess risk. N Engl J Med 352 (2005) 2122-2124
13. Jurkovitz C.T., Qiu Y., Wang C., Gilbertson D.T., and Brown W.W. The Kidney Early Evaluation Program (KEEP): program design and demographic characteristics of the population. Am J Kidney Dis 51 suppl 2 (2008) S3-S12
14. Research Data Assistance Center. Medicare data file descriptions (2009). http://www.resdac.umn.edu/Medicare/file_descriptions.asp#inpatient Accessed September 18, 2009
15. Levey A.S., Coresh J., Greene T., et al. Using standardized serum creatinine values in the Modification of Diet in Renal Disease Study equation for estimating glomerular filtration rate. Ann Intern Med 145 (2006) 247-254
16. Stevens L.A., and Stoycheff N. Standardization of serum creatinine and estimated glomerular filtration rate in the National Kidney Foundation Kidney Early Evaluation Program (KEEP). Am J Kidney Dis 51 suppl 2 (2008) S77-S82
17. Selvin E., Manzi J., Stevens L.A., et al. Calibration of serum creatinine in the National Health and Nutrition Examination Surveys (NHANES) 1988-1994, 1999-2004. Am J Kidney Dis 50 (2007) 918-926
18. Chobanian A.V., Bakris G.L., Black H.R., et al. Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure. Hypertension 42 (2003) 1206-1252
19. National Kidney Foundation. K/DOQI Clinical Practice Guidelines for Anemia of Chronic Kidney Disease (2006). http://www.kidney.org/professionals/kdoqi/guidelines_anemia/guide2.htm#cpr11 Accessed September 18, 2009
20. US Renal Data System. USRDS 2007 Annual Data Report, vol II (2007), National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD
21. Lane J.S., Vittinghoff E., Lane K.T., Hiramoto J.S., and Messina L.M. Risk factors for premature peripheral vascular disease: results for the National Health and Nutritional Survey, 1999-2002. J Vasc Surg 44 (2006) 319-324
22. Stevens L.A., Coresh J., and Levey A.S. CKD in the elderly-old questions and new challenges: World Kidney Day 2008. Am J Kidney Dis 51 (2008) 353-357
23. Levey A.S., Stevens L.A., Schmid C.H., et al. A new equation to estimate glomerular filtration rate. Ann Intern Med 150 (2009) 604-612
24. Zhang L., Zhang P., Wang F., et al. Prevalence and factors associated with CKD: a population study from Beijing. Am J Kidney Dis 51 (2008) 373-384
25. US Renal Data System. USRDS 2008 Annual Data Report, vol 1 (2008), National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD
26. Glassock R.J. Estimated glomerular filtration rate: time for a performance review?. Kidney Int 75 (2009) 1001-1003
27. Glassock R.J., and Winearls C. An epidemic of chronic kidney disease: fact or fiction?. Nephrol Dial Transplant 23 (2008) 1117-1121
28. Glassock R.J., and Winearls C. Screening for CKD with eGFR: doubts and dangers. Clin J Am Soc Nephrol 3 (2008) 1563-1568
29. Melamed M.L., Bauer C., and Hostetter T.H. eGFR: is it ready for early identification of CKD?. Clin J Am Soc Nephrol 3 (2008) 1569-1572
30. Kasiske B.L. Relationship between vascular disease and age-associated changes in the human kidney. Kidney Int 31 (1987) 1153-1159
31. Anderson S., and Brenner B.M. Effects of aging on the renal glomerulus. Am J Med 80 (1986) 435-442
32. Stevens L.A., Fares G., Fleming J., et al. Low rates of testing and diagnostic codes usage in a commercial clinical laboratory: evidence for lack of physician awareness of chronic kidney disease. J Am Soc Nephrol 16 (2005) 2439-2448
33. Lentine K.L., Schnitzler M.A., Abbott K.C., Bramesfeld K., Buchanan P.M., and Brennan D.C. Sensitivity of billing claims for cardiovascular disease events among kidney transplant recipients. Clin J Am Soc Nephrol 4 (2009) 1213-1221
34. Duru O.K., Vargas R.B., Kermah D., Nissenson A.R., and Norris K.C. High prevalence of stage 3 chronic kidney disease in older adults despite normal serum creatinine. J Gen Intern Med 24 (2009) 86-92
35. Jain A.K., McLeod I., and Huo C. When laboratories report estimated glomerular filtration rates in addition to serum creatinines, nephrology consults increase. Kidney Int 76 (2009) 318-323
36. Dukkipati R., Adler S., and Mehrotra R. Cardiovascular implications of chronic kidney disease in older adults. Drugs Aging 25 (2008) 241-253
37. Fried L.P., Ferrucci L., Darer J., Williamson J.D., and Anderson G. Untangling the concepts of disability, frailty, and comorbidity: implications for improved targeting and care. J Gerontol A Biol Sci Med Sci 59 (2004) 255-263
38. Grobner T., and Prischl F.C. Gadolinium and nephrogenic systemic fibrosis. Kidney Int 72 (2007) 260-264
39. Hurst F.P., Bohen E.M., Osgard E.M., et al. Association of oral sodium phosphate purgative use with acute kidney injury. J Am Soc Nephrol 18 (2007) 3192-3198
40. Steinman M.A., Landefeld C.S., Rosenthal G.E., Berthenthal D., Sen S., and Kaboli P.J. Polypharmacy and prescribing quality in older people. J Am Geriatr Soc 54 (2006) 1516-1523
41. Stevens L.A., Coresh J., Feldman H.I., et al. Evaluation of the Modification of Diet in Renal Disease Study Equation in a large diverse population. J Am Soc Nephrol 18 (2007) 2749-2757