Revisiting the natural history of tuberculosis : tthe inclusion of constant reinfection, host tolerance, and damage-response frameworks leads to a better understanding of latent infection and its evolution towards active disease

Archivum Immunologiae et Therapiae Experimentalis

Volumn 58, Issue 1, 2010, Pages 7-14

  Cardona, Pere Joan ^a,b  

^a UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

^b INSTITUTO DE SALUD CARLOS III   (Spain)

Author keywords

Damage framework response; Dynamic hypothesis; Foamy macrophages; Mycobacterium tuberculosis; Tolerance theory

Indexed keywords

ANTIBIOTIC AGENT; ISONIAZID;

BACILLUS; BACTERIAL GROWTH; BACTERIAL VIRULENCE; CELL TYPE; CELLULAR IMMUNITY; COLONY FORMING UNIT; DISEASE COURSE; GUINEA PIG; HUMAN; IMMUNE RESPONSE; IMMUNOCOMPROMISED PATIENT; IMMUNOLOGICAL TOLERANCE; IMMUNOSUPPRESSIVE TREATMENT; LIFE CYCLE; LUNG LOBE; LUNG TUBERCULOSIS; MACROPHAGE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PATHOGENESIS; PATHOPHYSIOLOGY; REINFECTION; REVIEW; TREATMENT DURATION; TUBERCULOSIS; VACCINATION;

ANIMALS; HUMANS; IMMUNE TOLERANCE; IMMUNITY, INNATE; MACROPHAGES, ALVEOLAR; MODELS, IMMUNOLOGICAL; MYCOBACTERIUM TUBERCULOSIS; REACTION TIME; RECURRENCE; TUBERCULOSIS; VIRULENCE;

EID: 76649139447     PISSN: 0004069X     EISSN: 16614917     Source Type: Journal    
DOI: 10.1007/s00005-009-0062-5     Document Type: Review

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