Autonomic function in hypertension role of genetic variation at the catecholamine storage vesicle protein chromogranin B

Circulation: Cardiovascular Genetics

Volumn 2, Issue 1, 2009, Pages 46-56

  Zhang, Kuixing ^a   Rao, Fangwen ^a   Rana, Brinda K ^a   Gayen, Jiaur R ^a   Calegari, Federico ^b   King, Angus ^b   Rosa, Patrizia ^d   Huttner, Wieland B ^b   Stridsberg, Mats ^c   Mahata, Manjula ^a   Vaingankar, Sucheta ^a   Mahboubi, Vafa ^a   Salem, Rany M ^a   Rodriguez Flores, Juan L ^a   Fung, Maple M ^a   Smith, Douglas W ^a   Schork, Nicholas J ^a   Ziegler, Michael G ^a   Taupenot, Laurent ^a   Mahata, Sushil K ^a   O'Connor, Daniel T ^a   more..

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b MAX PLANCK INSTITUTE OF MOLECULAR CELL BIOLOGY AND GENETICS   (Germany)

^c UPPSALA UNIVERSITY   (Sweden)

^d UNIVERSITY OF MILAN   (Italy)

Author keywords

Autonomic; Catecholamine; Epidemiology; Gene expression; Genetics; Hypertension; Nervous system

Indexed keywords

CATECHOLAMINE; CHROMOGRANIN B;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTONOMIC NERVOUS SYSTEM FUNCTION; BLOOD PRESSURE; CARDIOVASCULAR DISEASE; CATECHOLAMINE RELEASE; CHROMAFFIN CELL; CIRCULATION; DIASTOLIC BLOOD PRESSURE; ENVIRONMENTAL STRESS; EXON; FEMALE; GENE EXPRESSION; GENE LOCUS; GENETIC POLYMORPHISM; GENETIC TRANSFECTION; GENETIC VARIABILITY; HAPLOTYPE; HUMAN; HYPERTENSION; INTRON; MAJOR CLINICAL STUDY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; SEX DIFFERENCE; SINGLE NUCLEOTIDE POLYMORPHISM; SITE DIRECTED MUTAGENESIS; SYSTOLIC BLOOD PRESSURE; UNTRANSLATED REGION; ALLELE; ANIMAL; DISEASE PREDISPOSITION; GENETICS; METABOLISM; MOUSE MUTANT; PHENOTYPE; SECRETORY VESICLE; TWINS;

MUS;

ALLELES; ANIMALS; CATECHOLAMINES; CHROMOGRANIN B; DISEASE SUSCEPTIBILITY; FEMALE; GENETIC VARIATION; HAPLOTYPES; HUMANS; HYPERTENSION; MALE; MICE; MICE, KNOCKOUT; MUTAGENESIS, SITE-DIRECTED; PHENOTYPE; POLYMORPHISM, SINGLE NUCLEOTIDE; PROMOTER REGIONS, GENETIC; SECRETORY VESICLES; TWINS;

EID: 76649137391     PISSN: 1942325X     EISSN: 19423268     Source Type: Journal    
DOI: 10.1161/CIRCGENETICS.108.785659     Document Type: Article

References (44)

1. Binder A. A review of the genetics of essential hypertension. Curr Opin Cardiol. 2007; 22: 176-184.
2. Taupenot L, Harper KL, O'Connor DT. The chromogranin-secretogranin family. N Engl J Med. 2003; 348: 1134-1149.
3. Rosa P, Hille A, Lee RW, Zanini A, De Camilli P, Huttner WB. Secretogranins I and II: two tyrosine-sulfated secretory proteins common to a variety of cells secreting peptides by the regulated pathway. J Cell Biol. 1985; 101: 1999-2011.
4. Falkensammer G, Fischer-Colbrie R, Winkler H. Biogenesis of chromaffin granules: incorporation of sulfate into chromogranin B and into a proteoglycan. J Neurochem. 1985; 45: 1475-1480.
5. O'Connor DT, Frigon RP, Sokoloff RL. Human chromogranin A. Purification and characterization from catecholamine storage vesicles of human pheochromocytoma. Hypertension. 1984; 6: 2-12.
6. Schober M, Fischer-Colbrie R, Schmid KW, Bussolati G, O'Connor DT, Winkler H. Comparison of chromogranins A, B, and secretogranin II in human adrenal medulla and pheochromocytoma. Lab Invest. 1987; 57: 385-391.
7. Huh YH, Jeon SH, Yoo SH. Chromogranin B-induced secretory granule biogenesis: comparison with the similar role of chromogranin A. J Biol Chem. 2003; 278: 40581-40589.
8. Gill BM, Barbosa JA, Dinh TQ, Garrod S, O'Connor DT. Chromogranin B: isolation from pheochromocytoma, N-terminal sequence, tissue distribution and secretory vesicle processing. Regul Pept. 1991; 33: 223-235.
9. Natori S, Huttner WB. Chromogranin B (secretogranin I) promotes sorting to the regulated secretory pathway of processing intermediates derived from a peptide hormone precursor. Proc Natl Acad Sci USA. 1996; 93: 4431-4436.
10. Mahapatra NR, Mahata M, Datta AK, Gerdes HH, Huttner WB, O'Connor DT, Mahata SK. Neuroendocrine cell type-specific and inducible expression of the chromogranin B gene: crucial role of the proximal promoter. Endocrinology. 2000; 141: 3668-3678.
11. O'Connor DT, Kailasam MT, Kennedy BP, Ziegler MG, Yanaihara N, Parmer RJ. Early decline in the catecholamine release-inhibitory peptide catestatin in humans at genetic risk of hypertension. J Hypertens. 2002; 20: 1335-1345.
12. Waalen J, Felitti V, Gelbart T, Ho NJ, Beutler E. Prevalence of coronary heart disease associated with HFE mutations in adults attending a health appraisal center. Am J Med. 2002; 113: 472-479.
13. Rana BK, Insel PA, Payne SH, Abel K, Beutler E, Ziegler MG, Schork NJ, O'Connor DT. Population-based sample reveals gene-gender interactions in blood pressure in white Americans. Hypertension. 2007; 49: 96-106.
14. Rao F, Zhang L, Wessel J, Zhang K, Wen G, Kennedy BP, Rana BK, Das M, Rodriguez-Flores JL, Smith DW, Cadman PE, Salem RM, Mahata SK, Schork NJ, Taupenot L, Ziegler MG, O'Connor DT. Tyrosine hydroxylase, the rate-limiting enzyme in catecholamine biosynthesis: discovery of common human genetic variants governing transcription, autonomic activity, and blood pressure in vivo. Circulation. 2007; 116: 993-1006.
15. Almasy L, Blangero J. Multipoint quantitative-trait linkage analysis in general pedigrees. Am J Hum Genet. 1998; 62: 1198-1211.
16. Halperin E, Eskin E. Haplotype reconstruction from genotype data using imperfect phylogeny. Bioinformatics. 2004; 20: 1842-1849. (Pubitemid 39199048)
17. Stephens M, Donnelly P. A comparison of bayesian methods for haplotype reconstruction from population genotype data. Am J Hum Genet. 2003; 73: 1162-1169.
18. Abecasis GR, Cookson WO. GOLD-graphical overview of linkage disequilibrium. Bioinformatics. 2000; 16: 182-183.
19. Fallin D, Schork NJ. Accuracy of haplotype frequency estimation for biallelic loci, via the expectation-maximization algorithm for unphased diploid genotype data. Am J Hum Genet. 2000; 67: 947-959.
20. Fallin D, Cohen A, Essioux L, Chumakov I, Blumenfeld M, Cohen D, Schork NJ. Genetic analysis of case/control data using estimated haplotype frequencies: application to APOE locus variation and Alzheimer's disease. Genome Res. 2001; 11: 143-151.
21. Zaykin DV, Westfall PH, Young SS, Karnoub MA, Wagner MJ, Ehm MG. Testing association of statistically inferred haplotypes with discrete and continuous traits in samples of unrelated individuals. Hum Hered. 2002; 53: 79-91.
22. Clarkson D, Fan, Y-A, and Joe H. A remark on algorithm 643: FEXACT: An algorithm for performing Fisher's exact test in RxC contingency tables. ACM T Math Software. 1993; 19: 484-488.
23. Do KA, Broom BM, Kuhnert P, Duffy DL, Todorov AA, Treloar SA, Martin NG. Genetic analysis of the age at menopause by using estimating equations and Bayesian random effects models. Stat Med. 2000; 19: 1217-1235.
24. Eskeland NL, Zhou A, Dinh TQ, Wu H, Parmer RJ, Mains RE, O'Connor DT. Chromogranin A processing and secretion: specific role of endogenous and exogenous prohormone convertases in the regulated secretory pathway. J Clin Invest. 1996; 98: 148-156.
25. Folkow B. Physiological aspects of primary hypertension. Physiol Rev. 1982; 62: 347-504.
26. Schlaich MP, Lambert E, Kaye DM, Krozowski Z, Campbell DJ, Lambert G, Hastings J, Aggarwal A, Esler MD. Sympathetic augmentation in hypertension: role of nerve firing, norepinephrine reuptake, and Angiotensin neuromodulation. Hypertension. 2004; 43: 169-175.
27. Lambert E, Straznicky N, Schlaich M, Esler M, Dawood T, Hotchkin E, Lambert G. Differing pattern of sympathoexcitation in normal-weight and obesity-related hypertension. Hypertension. 2007; 50: 862-868.
28. Palatini P, Longo D, Zaetta V, Perkovic D, Garbelotto R, Pessina AC. Evolution of blood pressure and cholesterol in stage 1 hypertension: role of autonomic nervous system activity. J Hypertens. 2006; 24: 1375-1381.
29. De Vogli R, Brunner E, Marmot MG. Unfairness and the social gradient of metabolic syndrome in the Whitehall II Study. J Psychosom Res. 2007; 63: 413-419.
30. Cowley AW Jr. The genetic dissection of essential hypertension. Nat Rev Genet. 2006; 7: 829-840.
31. Zhang B, Tan Z, Zhang C, Shi Y, Lin Z, Gu N, Feng G, He L. Polymorphisms of chromogranin B gene associated with schizophrenia in Chinese Han population. Neurosci Lett. 2002; 323: 229-233. (Pubitemid 34311918)
32. Iijima Y, Inada T, Ohtsuki T, Senoo H, Nakatani M, Arinami T. Association between chromogranin b gene polymorphisms and schizophrenia in the Japanese population. Biol Psychiatry. 2004; 56: 10-17. (Pubitemid 38813400)
33. Goldner EM, Hsu L, Waraich P, Somers JM. Prevalence and incidence studies of schizophrenic disorders: a systematic review of the literature. Can J Psychiatry. 2002; 47: 833-843.
34. Courel M, Rodemer C, Nguyen ST, Pance A, Jackson AP, O'Connor DT, Taupenot L. Secretory granule biogenesis in sympathoadrenal cells: identification of a granulogenic determinant in the secretory prohormone chromogranin A. J Biol Chem. 2006; 281: 38038-38051.
35. Mahapatra NR, O'Connor DT, Vaingankar SM, Hikim AP, Mahata M, Ray S, Staite E, Wu H, Gu Y, Dalton N, Kennedy BP, Ziegler MG, Ross J, Mahata SK. Hypertension from targeted ablation of chromogranin A can be rescued by the human ortholog. J Clin Invest. 2005; 115: 1942-1952. (Pubitemid 40979734)
36. Portela-Gomes GM, Stridsberg M. Region-specific antibodies to chromogranin B display various immunostaining patterns in human endocrine pancreas. J Histochem Cytochem. 2002; 50: 1023-1030. (Pubitemid 34827624)
37. Mahapatra NR, Mahata M, Ghosh S, Gayen JR, O'Connor DT, Mahata SK. Molecular basis of neuroendocrine cell type-specific expression of the chromogranin B gene: Crucial role of the transcription factors CREB, AP-2, Egr-1 and Sp1. J Neurochem. 2006; 99: 119-133. (Pubitemid 44395135)
38. D'Agostino RB Sr, Vasan RS, Pencina MJ, Wolf PA, Cobain M, Massaro JM, Kannel WB. General cardiovascular risk profile for use in primary care: the Framingham Heart Study. Circulation. 2008; 117: 743-753. (Pubitemid 351640675)
39. Knowler WC, Williams RC, Pettitt DJ, Steinberg AG. Gm3;5, 13, 14 and type 2 diabetes mellitus: an association in Am Indians with genetic admixture. Am J Hum Genet. 1988; 43: 520-526.
40. King D, Etzel JP, Chopra S, Smith J, Cadman PE, Rao F, Funk SD, Rana BK, Schork NJ, Insel PA, O'Connor DT. Human response to alpha2-adrenergic agonist stimulation studied in an isolated vascular bed in vivo: biphasic influence of dose, age, gender, and receptor genotype. Clin Pharmacol Ther. 2005; 77: 388-403. (Pubitemid 40719267)
41. Kneale BJ, Chowienczyk PJ, Brett SE, Coltart DJ, Ritter JM. Gender differences in sensitivity to adrenergic agonists of forearm resistance vasculature. J Am Coll Cardiol. 2000; 36: 1233-1238.
42. Kasagi F, Akahoshi M, Shimaoka K. Relation between cold pressor test and development of hypertension based on 28-year follow-up. Hypertension. 1995; 25: 71-76.
43. Markovitz JH, Raczynski JM, Wallace D, Chettur V, Chesney MA. Cardiovascular reactivity to video game predicts subsequent blood pressure increases in young men: the CARDIA study. Psychosom Med. 1998; 60: 186-191. (Pubitemid 28160532)
44. Mayor C, Brudno M, Schwartz JR, Poliakov A, Rubin EM, Frazer KA, Pachter LS, Dubchak I. VISTA: visualizing global DNA sequence alignments of arbitrary length. Bioinformatics. 2000; 16: 1046-1047. (Pubitemid 32051021)