Diagnosis and staging of mild cognitive impairment, using a modification of the clinical dementia rating scale: The mCDR

International Journal of Geriatric Psychiatry

Volumn 25, Issue 3, 2010, Pages 282-289

  Duara, Ranjan ^a,b,c,d   Loewenstein, David A ^a,b   Greig Custo, Maria T ^a   Raj, Ashok ^c,d   Barker, Warren ^a   Potter, Elizabeth ^a   Schofield, Elizabeth ^d   Small, Brent ^c,d   Schinka, John ^c,d,e   Wu, Yougui ^c,d   Potter, Huntington ^c,d  

^a MOUNT SINAI MEDICAL CENTER   (United States)

^b UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF SOUTH FLORIDA   (United States)

^d UNIVERSITY OF SOUTH FLORIDA   (United States)

^e VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Clinical rating scale; Dementia; Mild cognitive impairment; MRI; Visual rating

Indexed keywords

AGED; AMNESIA; ARTICLE; BRAIN ATROPHY; DEMENTIA; DIAGNOSTIC TEST; DIAGNOSTIC VALUE; DISEASE COURSE; FEMALE; FOLLOW UP; HUMAN; INTERRATER RELIABILITY; MAJOR CLINICAL STUDY; MALE; MEMORY; MILD COGNITIVE IMPAIRMENT; MODIFICATION OF CLINICAL DEMENTIA RATING SCALE; MULTIPLE CHOICE TEST; NEUROPSYCHOLOGICAL TEST; NUCLEAR MAGNETIC RESONANCE IMAGING; RELIABILITY; SCORING SYSTEM; STRUCTURED INTERVIEW; VALIDITY;

AGED; AGED, 80 AND OVER; ATROPHY; COGNITION DISORDERS; DEMENTIA; FEMALE; FOLLOW-UP STUDIES; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; NEUROPSYCHOLOGICAL TESTS; OBSERVER VARIATION; PREDICTIVE VALUE OF TESTS; PROGNOSIS; PSYCHIATRIC STATUS RATING SCALES; QUESTIONNAIRES; REPRODUCIBILITY OF RESULTS; SEVERITY OF ILLNESS INDEX; TEMPORAL LOBE;

EID: 76649131279     PISSN: 08856230     EISSN: 10991166     Source Type: Journal    
DOI: 10.1002/gps.2334     Document Type: Article

References (33)

1. Beekly DL, Ramos EM, Lee WW, et al. 2007. NIA Alzheimer's disease centers. The National Alzheimer's Coordinating Center (NACC) Database: the uniform data set. Alzheimer Dis Assoc Disord 21: 249-258.
2. Benton AL, Hamsher K. 1989. Multilingual Aphasia Examination: Manual of Instructions, 2nd edn. AJA Associates: Iowa City, Iowa.
3. Bobinski M, Wegiel J, Wisniewski HM, et al. 1996. Neurofibrillary pathology - correlation with hippocampal formation atrophy in Alzheimer disease. Neurobiol Aging 17: 909-919.
4. Chen HH, Duffy SW, Tabar L. 1996. A Markov chain method to estimate the tumor progression rate from preclinical to clinical phase, sensitivity and positive predictive value for mammography in breast cancer screening. The Statistician 45: 307-317.
5. Cohen J, Cohen P. 1983. Applied Multiple Regression/Correlation Analysis for the Behavioral Sciences. Lawrence Erlbaum Assoc: Hillsdale, New York.
6. Delong ER, Delong DM, Clarke-Pearson DL. 1988. Comparing the areas under two or more correlated receiver operating characteristic curves: a nonparametric approach. Biometrics 44: 837-845.
7. Duara R, Loewenstein DA, Potter E, et al. 2008. Medical temporal lobe atrophy on MRI Scans and the diagnosis of Alzheimer's disease. Neurology 71: 1986-1992.
8. Fillenbaum GG, Peterson B, Morris JC. 1996. Estimating the validity of the clinical dementia rating scale: the CERAD experience. Consortium to establish a registry for Alzheimer's disease. Aging (Milano) 8: 379-385.
9. Fleisher AS, Raman R, Siemers ER, et al. 2008. Phase 2 safety trial targeting amyloid beta production with a gamma secretase inhibitor in Alzheimer's disease. Arch Neurol 65: 1031-1038.
10. Fuld PA. 1981. Fuld Object-Memory Evaluation. Stoelting Company: Wood Dale, IL.
11. Galvin JE, Roe CM, Morris JC. 2007. Evaluation of cognitive impairment in older adults combining brief informant and performance measures. Arch Neurol 64: 718-724.
12. Hanninen T, Hallikainen M, Tuomainen S, Vanhanen M, Soininen H. 2002. Prevalence of mild cognitive impairment: a population-based study in elderly subjects. Acta Neurol Scand 106: 148-154.
13. Jack CR, Dickson DW, Parisi JE, et al. 2002. Antemortem MRI findings correlate with hippocampal neuropathology in typical aging and dementia. Neurology 58: 750-757.
14. Keys A, Fidanza F, Karvonen MJ, Kimura N, Taylor HL. 1972. Indices of relative weight and obesity. J Chron Dis 25: 329-343.
15. Killiany RJ, Hyman BT, Gomez-Isla T, et al. 2002. MRI measures of entorhinal cortex versus hippocampus in preclinical AD. Neurology 58: 1188-1196.
16. Li M, Ng TP, Kua EH, Ko SM. 2006. Brief informant screening test for mild cognitive impairment and early Alzheimer's disease. Dement Geriatr Cogn Disord 21: 392-402.
17. Lim WS, Chong MS, Sahadevan S. Review: utility of the clinical dementia rating in Asian populations. Clin Med Res 2007. 5: 61-70.
18. Loewenstein DA, Argüelles T, Barker WW, et al. 2001. The utility of a modified object memory test in distinguishing between three different age groups of Alzheimer's disease patients and normal controls. J Mental Health Aging 7: 317-324.
19. Loewenstein DA, Acevedo A, Agron J, et al. 2006. Cognitive profiles in Alzheimer's disease and in mild cognitive impairment of different etiologies. Dement Geriatr Cogn Disord 21: 309-315.
20. McCulla MM, Coats M, Van Fleet N, et al. 1989. Reliability of clinical nurse specialists in the staging of dementia. Arch Neurol 46: 1210-1211.
21. Monsch AU, Bondi MW, Butter N, et al. 1992. Comparisons of verbal fluency tasks in the detection of dementia of the Alzheimer type. Arch Neurol 49: 1253-1258.
22. Morris JC. 1993. The clinical dementia rating (CDR): current version and scoring rules. Neurology 43: 2412-2414.
23. Morris JC. 1997. Clinical dementia rating: a reliable and valid diagnostic and staging measure for dementia of the Alzheimer type. Intl Psychogeriatrics 9(Supp 1): 173-176.
24. Perneczky R, Wagenpfeil S, Komossa K, et al. Mapping scores onto stages: mini-mental state examination and clinical dementia rating. Am J Geriatr Psychiatry 14: 139-144.
25. Petersen RC. 2000. Mild cognitive impairment or questionable dementia? Arch Neurol 57: 643-644.
26. Rockwood K, Strang D, MacKnight C, Downer R, Morris JC. 2000. Interrater reliability of the clinical dementia rating in a multicenter trial. J Am Geriatrics Soc 48: 558-559.
27. Rusinek H, Endo Y, De Santi S, et al. 2004. Atrophy rate in medial temporal lobe during progression of Alzheimer disease. Neurology 63: 2354-2359.
28. Schafer KA, Tractenberg RE, Sano M, et al. 2004. Alzheimer's disease cooperative study. Reliability of monitoring the clinical dementia rating in multicenter clinical trials. Alzheimer Dis Assoc Disord 18: 219-222.
29. Spreen O, Strauss E. 1998. A Compendium of Neuropsychological Tests: Administration, Norms, and Commentary, 2nd edn. Oxford University Press: New York.
30. Tabert MH, Albert SM, Borukhova-Milov L, et al. 2002. Functional deficits in patients with mild cognitive impairment: prediction of Alzheimer's disease. Neurology 58: 758-764.
31. Urs R, Potter E, Barker W, et al. 2009. Visual rating system (VRS) for assessing magnetic resonance images (MRIs): a tool in the diagnosis of MCI and Alzheimer's disease. J Comput Assist Tomogr 33: 73-78.
32. Wechsler D. 1987. The Wechsler Memory Scale, revised. The Psychological Corporation: San Antonio.
33. Wechsler D. 1997. The Wechsler Adult Intelligence Scale, 3rd edn. The Psychological Corporation: San Antonio.