Levosalbutamol vs racemic salbutamol in the treatment of acute exacerbation of asthma

Indian Journal of Pediatrics

Volumn 76, Issue 11, 2009, Pages 1131-1135

  Punj, Ajay ^a   Prakash, Ashish ^a   Bhasin, Ashu ^a  

^a SUBHARTI MEDICAL COLLEGE   (India)

Author keywords

Asthma; Levosalbutamol; Racemic Salbutamol

Indexed keywords

LEVALBUTEROL; SALBUTAMOL;

ADOLESCENT; ADULT; ARTICLE; ASTHMA; BREATHING RATE; CHILD; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISEASE EXACERBATION; DISEASE SEVERITY; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG TOLERABILITY; FEMALE; HEART RATE; HUMAN; MAJOR CLINICAL STUDY; MALE; OXYGEN SATURATION; PEAK EXPIRATORY FLOW; POTASSIUM BLOOD LEVEL; PRESCHOOL CHILD; RANDOMIZED CONTROLLED TRIAL; SCHOOL CHILD; SCORING SYSTEM; SIDE EFFECT; TACHYCARDIA; TACHYPNEA; TREATMENT DURATION; TREATMENT OUTCOME;

ACUTE DISEASE; ALBUTEROL; ASTHMA; BRONCHODILATOR AGENTS; CHILD; CHILD, PRESCHOOL; DOUBLE-BLIND METHOD; DRUG ADMINISTRATION SCHEDULE; FEMALE; HEART RATE; HUMANS; MALE; POTASSIUM; SEVERITY OF ILLNESS INDEX;

EID: 76649124870     PISSN: 00195456     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12098-009-0245-4     Document Type: Article

References (22)

1. R.B. Penn T. Frielle F.R. McCullough G. Aberg J. Benovic 1996 Comparison of R-, S- and RS-albuterol interaction with human β1-and β2 adrenergic receptors Clin Rev Allergy Immunol 14 37 45 10.1007/BF02772201 1:STN:280:DyaK2s%2FhvFKqtA%3D%3D 8866170
2. P. Clive M. Jhon 1999 Contrasting properties of albuterol stereoisomers J Allergy Clin Immuno 104 S31 S41 10.1016/S0091-6749(99)70271-X (Pubitemid 29426707)
3. R.M. Nowak C.L. Emerman K. Schaefer R.L. Disantosterfano L. Vaickus J.M. Roach 2004 Levalbuterol compared with racemic albuterol in the treatment of acute asthma: results of a polot study Am J Emerg Med 22 29 36 10.1016/j.ajem.2003.11.001 14724875 (Pubitemid 38146307)
4. J.C. Carl T.R. Myers H.L. Kirchner C.M. Kercsmar 2003 Comparison of racemic albuterol and levalbuterol for treatment of acute asthma J Pediatr 143 731 736 10.1067/S0022-3476(03)00493-1 1:CAS:528:DC%2BD2cXivFSmuw%3D%3D 14657817 (Pubitemid 37510640)
5. M.E. Ralston M.S. Euwema K.R. Knecht T.J. Ziolkowski T.A. Coakley S.M. Cline 2005 Comparison of levalbuterol and racemic albuterol combined with ipratropium bromide in acute pediatric asthma: a randomized controlled trial J Emerg Med 29 29 35 10.1016/j.jemermed.2005.02.003 15961004 (Pubitemid 40800235)
6. H. Milgrom C.P. Skoner G. Bensch K.T. Kim R. Claus R.A. Baumgartner 2001 Low-dose levalbuterol in children with asthma: safety and efficacy in comparision with placebo and racemic albuterol J Allergy Clin Immunol 108 938 945 10.1067/mai.2001.120134 1:CAS:528:DC%2BD38XltVOhtA%3D%3D 11742271 (Pubitemid 33151546)
7. F. Qureshi J. Pestian P. Davis, et al. 1998 Effect of neubulised ipratropium on hospitalisation rates on children with asthma NEJM 339 1030 1035 10.1056/NEJM199810083391503 1:CAS:528:DyaK1cXmvV2itr4%3D 9761804 (Pubitemid 28457864)
8. B. Canning 2002 Pharmacological properties of S-albuterol in human airway smooth muscle preparations Am J Resp Crit Care Med 165 A 770
9. E.E. Van Essen-Zandvliet M.D. Hughes, et al. 1992 Effects of 22 months of treatment with inhaled salbutamol lung function, airway responsiveness, and symptom in children with asthma Am Rev Resp Dis 146 547 554 1355640
10. S. Keir C. Page D. Spina 2002 Bronchial hyper-responsiveness induced by chronic treatment with albuterol: role of sensory nerves J Allergy Clin Immunol 110 388 394 10.1067/mai.2002.126661 1:CAS:528:DC%2BD38XnvVSrur0%3D 12209084
11. A.G.B. Templeton I.D. Chapman E. Chilvers J. Morley D.A. Handley 1998 Effects of (S)-albuterol on isolated human bronchus Pulm Pharmacol 11 1 6 10.1006/pupt.1998.0110 1:CAS:528:DyaK1cXnsFSgurk%3D (Pubitemid 28510713)
12. L. Mazzoni R. Naef I.D. Chapman J. Morley 1994 Hyperresponsiveness of the airway to histamine following exposure of guinea pigs to racemic mixtures and distomers of β2 selective sympathomimetics Pulm Pharmacol 7 367 376 10.1006/pulp.1994.1043 1:CAS:528:DyaK2MXntVCrsLs%3D 7549224
13. D.W. Cockcroft V.A. Swystun 1997 Effect of single doses of S-Salbutamol, R-Salbutamol, racemic salbutamol, and placebo on the airway response to methacholine Thorax 52 845 848 10.1136/thx.52.10.845 1:STN:280: DyaK1c%2FmvVWrsg%3D%3D 9404369
14. 2 agonist isomers, has stimulatory effects on mucin secretion and changes in gene expression on airway epithelium Am J Resp Crit Care Med 161 A 144
15. B.T. Perterson E.J. Miller 2000 Effect of enatiomers of albuterol on lung epithelial permeability Am J REsp Crit Care Med 161 A 416
16. S. O'sulivan L. Cormican J.L. Faul S. Ichinohe S.L. Johnston, et al. 2001 Activated, Cytotoxic CD8 + T Lymphocytes contribute to the pathology of asthma death Am J Resp Crit Care Med 164 560 564
17. 2 adrenergic agonist on eosinophil response to IL-5 J Allergy Clin Immunolo 111 S35
18. S.H. Cho J.Y. Haartleroad C.K. Oh 2001 S-albuterol increases the production of histamine and IL-4 in mast cells Int Arch Allergy Imunolo 124 478 484 10.1159/000053783 1:CAS:528:DC%2BD3MXktVarsrc%3D (Pubitemid 32429691)
19. 2 agonist enantiomers of salbutamol J Allergy Clin Immunolo 105 S292 S293 10.1016/S0091-6749(00)91286-7
20. C.C. Kwong Q.N. Chung S.S. Choi, et al. 2002 Effects of isomers of albuterol, R-albuterol, and S-albuterol, on human granulocytic function J Invest Med 50 72 A
21. D. Haider 2001 Levalbuterol affords superior health and cost benefit over racemic albuterol in the emergency department Resp Care 46 1081
22. L.P. Malmberg K. NIkander A.S. Pelkonen, et al. 2001 Acceptability reproducibility, and sensitivity of forced expiratory volumes and peak expiratory flow during bronchial challenge testing in asthmatic children Chest 120 1843 1849 10.1378/chest.120.6.1843 1:STN:280:DC%2BD3MnpsVylsw%3D%3D 11742911 (Pubitemid 34053443)