Delivery of encapsulated doxorubicin by ultrasound-mediated size reduction of drug-loaded polymer contrast agents

IEEE Transactions on Biomedical Engineering

Volumn 57, Issue 1, 2010, Pages 24-28

  Eisenbrey, J R ^a   Soulen, M C ^b   Wheatley, M A ^a  

^a DREXEL UNIVERSITY   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Cancer therapy; Drug delivery; Ultrasound contrast agents; VX2 tumor

Indexed keywords

CANCER THERAPY; DOXORUBICIN; ENCAPSULATED DRUGS; FOCUSED ULTRASOUND; GAS RELEASE; IN-VITRO; IN-VIVO; LIVER TUMORS; MEAN PARTICLE SIZE; NON-TARGETED; PENETRATION MECHANISMS; PERIPHERAL TISSUE; POLYMER CONTRAST AGENTS; POLYMER PARTICLES; POSITIVE PRESSURE; SIZE REDUCTIONS; SUSTAINED RELEASE; TUMOR SITE; TUMOR VASCULATURE; ULTRASOUND CONTRAST AGENT; VASCULATURE; VX2 TUMOR;

ACOUSTIC WAVES; CHEMOTHERAPY; DRUG DELIVERY; LEAKAGE (FLUID); LIVER; SIZE DETERMINATION; ULTRASONICS;

TUMORS;

DOXORUBICIN; ECHO CONTRAST MEDIUM; POLYMER;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG DEGRADATION; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; DRUG RELEASE; DRUG TUMOR LEVEL; HIGH INTENSITY FOCUSED ULTRASOUND; IN VITRO STUDY; IN VIVO STUDY; LIVER TUMOR; MICROBUBBLE; NANOENCAPSULATION; NONHUMAN; PARTICLE SIZE; RABBIT; STATISTICAL ANALYSIS;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; CONTRAST MEDIA; DOXORUBICIN; DRUG DELIVERY SYSTEMS; DRUG SCREENING ASSAYS, ANTITUMOR; LACTIC ACID; LIVER NEOPLASMS, EXPERIMENTAL; MICROBUBBLES; POLYMERS; RABBITS; ULTRASONOGRAPHY;

EID: 76649116508     PISSN: 00189294     EISSN: None     Source Type: Journal    
DOI: 10.1109/TBME.2009.2030497     Document Type: Article

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