Radiosynthesis of novel carbon-11-labeled triaryl ligands for cannabinoid-type 2 receptor

Bioorganic and Medicinal Chemistry Letters

Volumn 20, Issue 5, 2010, Pages 1565-1568

  Fujinaga, Masayuki ^a   Kumata, Katsushi ^a   Yanamoto, Kazuhiko ^a   Kawamura, Kazunori ^a   Yamasaki, Tomoteru ^a   Yui, Joji ^a   Hatori, Akiko ^a   Ogawa, Masanao ^a,b   Yoshida, Yuichiro ^a,b   Nengaki, Nobuki ^a,b   Maeda, Jun ^a   Zhang, Ming Rong ^a  

^a NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCES   (Japan)

^b 141 0032   (Japan)

Author keywords

Brain uptake; Cannabinoid subtype 2; PET; Radiosynthesis; Triaryl ligands

Indexed keywords

CANNABINOID 2 RECEPTOR; CARBON 11; PHENOL DERIVATIVE; POLYCYCLIC AROMATIC HYDROCARBON DERIVATIVE; RADIOLIGAND;

ANIMAL TISSUE; ARTICLE; BRAIN; DRUG BINDING; DRUG POTENCY; DRUG SYNTHESIS; DRUG UPTAKE; IN VITRO STUDY; INJECTION; ISOTOPE LABELING; METHYLATION; NONHUMAN; POSITRON; POSITRON EMISSION TOMOGRAPHY; RADIOACTIVITY;

ANIMALS; BIPHENYL COMPOUNDS; BRAIN; CARBON RADIOISOTOPES; LIGANDS; MICE; POSITRON-EMISSION TOMOGRAPHY; PROTEIN BINDING; RADIOPHARMACEUTICALS; RECEPTOR, CANNABINOID, CB2; THIOPHENES;

EID: 76649104709     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2010.01.074     Document Type: Article

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