Effects of BMP-2 and dexamethasone on osteogenic differentiation of rat dental follicle progenitor cells seeded on three-dimensional β-TCP

Biomedical Materials

Volumn 4, Issue 6, 2009, Pages

  Xu, Lu Lu ^a,b   Liu, Hong Chen ^b   Wang, Dong Sheng ^b   Ling Ling, E ^b   Xu, Lin ^c   Jin, Zuo Lin ^a   Duan, Yin Zhong ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b CHINESE PLA GENERAL HOSPITAL   (China)

^c First Hospital of PLA   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MATERIALS; BONE; CALCIUM; CALCIUM ALLOYS; CELL CULTURE; PHOSPHATASES; SCANNING ELECTRON MICROSCOPY; THREE DIMENSIONAL; TISSUE ENGINEERING;

2-GROUP; ALKALINE PHOSPHATASE; BONE FORMATION; BONE REGENERATION; CELLULAR ADHESION; CONTROL CONSTRUCTS; CONTROL GROUPS; DEXAMETHASONES; FOUR-GROUP; GROWTH OF CELLS; HISTOMORPHOMETRIC ANALYSIS; OSTEOCALCIN; OSTEOGENIC DIFFERENTIATION; PERIODONTAL TISSUE; PROGENITOR CELL; SCANNING ELECTRON MICROSCOPES;

TRANSMISSION CONTROL PROTOCOL;

ALKALINE PHOSPHATASE; BIOMATERIAL; BONE MORPHOGENETIC PROTEIN 2; CALCIUM PHOSPHATE; DEXAMETHASONE; OSTEOCALCIN; BETA-TRICALCIUM PHOSPHATE; CALCIUM;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE REGENERATION; CELL ADHESION; CELL CULTURE; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL STRUCTURE; CONCENTRATION RESPONSE; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVITY; HISTOPATHOLOGY; IMPLANTATION; MORPHOMETRICS; MOUSE; NONHUMAN; RAT; SCANNING ELECTRON MICROSCOPY; SCID MOUSE; STATISTICAL SIGNIFICANCE; STEM CELL; THREE DIMENSIONAL IMAGING; TISSUE ENGINEERING; TOOTH; ANIMAL; BONE DEVELOPMENT; CHEMISTRY; INSTRUMENTATION; METABOLISM; METHODOLOGY; MOUSE MUTANT; SPRAGUE DAWLEY RAT; TOOTH SAC;

MUS; RATTUS;

ALKALINE PHOSPHATASE; ANIMALS; BONE MORPHOGENETIC PROTEIN 2; BONE REGENERATION; CALCIUM; CALCIUM PHOSPHATES; CELL ADHESION; CELL DIFFERENTIATION; CELL PROLIFERATION; DENTAL SAC; DEXAMETHASONE; MICE; MICE, SCID; MICROSCOPY, ELECTRON, SCANNING; OSTEOCALCIN; OSTEOGENESIS; RATS; RATS, SPRAGUE-DAWLEY; TISSUE ENGINEERING;

EID: 76649103731     PISSN: 17486041     EISSN: 1748605X     Source Type: Journal    
DOI: 10.1088/1748-6041/4/6/065010     Document Type: Article

References (35)

1. Handa K, Saito M, Tsunoda A, Yamauchi M, Hattori S, Sato S, Toyoda M, Teranaka T and Narayanan A S 2002 Progenitor cells from dental follicle are able to form cementum matrix in vivo Connect. Tissue Res. 43 406-8 (Pubitemid 34784577)
2. Handa K, Saito M, Yamauchi M, Kiyono T, Sato S, Teranaka T and Sampath Narayanan A 2002 Cementum matrix formation in vivo by cultured dental follicle cells Bone 31 606-11 (Pubitemid 35449703)
3. Saito M et al 2005 Immortalization of cementoblast progenitor cells with Bmi-1 and TERT J. Bone Miner. Res. 20 50-7
4. Morsczeck C, Götz W, Schierholz J, Zeilhofer F, Kühn U, Möhl C, Sippel C and Hoffmann K H 2005 Isolation of precursor cells (PCs) from human dental follicle of wisdom teeth Matrix Biol. 24 155-65
5. Thesleff I, Vaahtokari A, Vainio S and Jowett A 1996 Molecular mechanisms of cell and tissue interactions during early tooth development Anat. Rec. 245 151-61
6. Luan X, Ito Y, Dangaria S and Diekwisch T G 2006 Dental follicle progenitor cell heterogeneity in the developing mouse periodontium Stem Cells Dev. 15 595-608
7. Morsczeck C, Moehl C, Götz W, Heredia A, Schäffer T E, Eckstein N, Sippel C and Hoffmann K H 2005 In vitro differentiation of human dental follicle cells with dexamethasone and insulin Cell Biol. Int. 29 567-75 (Pubitemid 41138220)
8. Zhao M, Xiao G, Berry J E, Franceschi R T, Reddi A and Somerman M J 2002 Bone morphogenetic protein 2 induces dental follicle cells to differentiate toward a cementoblast/osteoblast phenotype J. Bone Miner. Res. 17 1441-51
9. Hakki S S, Berry J E and Somerman M J 2001 The effect of enamel matrix protein derivative on follicle cells in vitro J. Periodontol. 72 679-87
10. Jin Q M, Zhao M, Webb S A, Berry J E, Somerman M J and Giannobile W V 2003 Cementum engineering with three-dimensional polymer scaffolds J. Biomed. Mater. Res. A 67 54-60
11. Ghosh-Choudhury N, Windle J J, Koop B A, Harris M A, Guerrero D L, Wozney J M, Mundy G R and Harris S E 1996 Immortalized murine osteoblasts derived from BMP2-T-antigen expressing transgenic mice Endocrinology 137 331-9
12. Kawakatsu N, Oda S, Kinoshita A, Kikuchi S, Tsuchioka H, Akizuki T, Hayashi C, Kokubo S, Ishikawa I and Izumi Y 2008 Effect of rhBMP-2 with PLGA/gelatin sponge type (PGS) carrier on alveolar ridge augmentation in dogs J. Oral Rehabil. 35 647-55
13. King G N and Hughes F J 2001 Bone morphogenetic protein-2 stimulates cell recruitment and cementogenesis during early wound healing J. Clin. Periodontol. 28 465-75
14. Choi S H, Kim C K, Cho K S, Huh J S, Sorensen R G, Wozney J M and Wikesjö U M 2002 Effect of recombinant human bone morphogenetic protein-2/absorbable collagen sponge (rhBMP-2/ACS) on healing in 3-wall intrabony defects in dogs J. Periodontol. 73 63-72
15. Ripamonti U, Crooks J, Petit J C and Rueger D C 2001 Periodontal tissue regeneration by combined applications of recombinant human osteogenic protein-1 and bone morphogenetic protein-2. A pilot study in Chacma baboons (Papio ursinus) Eur. J. Oral Sci. 109 241-8
16. Talwar R, Di Silvio L, Hughes F J and King G N 2001 Effects of carrier release kinetics on bone morphogenetic protein-2-induced periodontal regeneration in vivo J. Clin. Periodontol. 28 340-7
17. Cheng S L, Yang J W, Rifas L, Zhang S F and Avioli L V 1994 Differentiation of human bone marrow osteogenic stromal cells in vitro: induction of the osteoblast phenotype by dexamethasone Endocrinology 134 277-86
18. Cheng S L, Zhang S F, Mohan S, Lecanda F, Fausto A, Hunt A H, Canalis E and Avioli L V 1998 Regulation of insulin-like growth factors I and II and their binding proteins in human bone marrow stromal cells by dexamethasone J. Cell. Biochem. 71 449-58
19. Morsczeck C 2006 Gene expression of runx2, Osterix, c-fos, DLX-3, DLX-5, and MSX-2 in dental follicle cells during osteogenic differentiation in vitro Calcif. Tissue Int. 78 98-102
20. Grimm B, Miles A W and Turner I G 2001 Optimizing a hydroxyapatite/ tricalcium-phosphate ceramic as a bone graft extender for impaction grafting J. Mater. Sci., Mater. Med. 12 929-34
21. Zambonin G, Losito I, Triffitt J T and Zambonin C G 2000 Detection of collagen synthesis by human osteoblasts on a tricalcium phosphate hydroxyapatite: an x-ray photoelectron spectroscopy investigation J. Biomed. Mater. Res. 49 120-6
22. Sous M, Bareille R, Rouais F, Clément D, Amédée J, Dupuy B and Baquey Ch 1998 Cellular biocompatibility and resistance to compression of macroporous beta-tricalcium phosphate ceramics Biomaterials 19 2147-53
23. Rangavittal N, Landa-Cnovas A R, Gonzlez-Calbet J M and Vallet-Regí M 2000 Structural study and stability of hydroxyapatite and beta-tricalcium phosphate: two important bioceramics J. Biomed. Mater. Res. 51 660-8
24. Pioletti D P, Takei H, Lin T, Van Landuyt P, Ma Q J, Kwon S Y and Sung K L 2000 The effects of calcium phosphate cement particles on osteoblast functions Biomaterials 21 1103-14
25. Boo J S, Yamada Y, Okazaki Y, Hibino Y, Okada K, Hata K, Yoshikawa T, Sugiura Y and Ueda M 2002 Tissue-engineered bone using mesenchymal stem cells and a biodegradable scaffold J. Craniofac. Surg. 13 231-9 (discussion 240-3)
26. Mankani M H, Kuznetsov S A, Fowler B, Kingman A and Robey P G 2001 In vivo bone formation by human bone marrow stromal cells: effect of carrier particle size and shape Biotechnol. Bioeng. 72 96-107
27. Matsumura K, Hyon S H, Nakajima N, Iwata H, Watazu A and Tsutsumi S 2004 Surface modification of poly(ethylene-co-vinyl alcohol): hydroxyapatite immobilization and control of periodontal ligament cells differentiation Biomaterials 25 4817-24 (Pubitemid 38561169)
28. Wise G E, Lin F and Fan W 1992 Culture and characterization of dental follicle cells from rat molars Cell Tissue Res. 267 483-92
29. Bellows C G, Aubin J E, Heersche J N and Antosz M E 1986 Mineralized bone nodules formed in vitro from enzymatically released rat calvaria cell populations Calcif. Tissue Int. 38 143-54
30. Väkevä L, Mackie E, Kantomaa T and Thesleff I 1990 Comparison of the distribution patterns of tenascin and alkaline phosphatase in developing teeth, cartilage, and bone of rats and mice Anat. Rec. 228 69-76
31. Kémoun P et al 2007 Human dental follicle cells acquire cementoblast features under stimulation by BMP-2/-7 and enamel matrix derivatives (EMD) in vitro Cell Tissue Res. 329 283-94
32. Li X, Gao H, Uo M, Sato Y, Akasaka T, Abe S, Feng Q, Cui F and Watari F 2009 Maturation of osteoblast-like SaoS2 induced by carbon nanotubes Biomed. Mater. 4 15005
33. Li X, van Blitterswijk C A, Feng Q, Cui F and Watari F 2008 The effect of calcium phosphate microstructure on bone-related cells in vitro Biomaterials 29 3306-16
34. Li X, Liu X, Dong W, Feng Q, Cui F, Uo M, Akasaka T and Watari F 2009 In vitro evaluation of porous poly (l-Lactiv acid) scaffold J. Biomed. Mater. Res. 90B 503-9
35. Li X, Gao H, Uo M, Sato Y, Akasaka T, Feng Q, Cui F, Liu X and Watari F 2009 Effect of carbon nanotubes cellular functions in vitro J. Biomed. Mater. Res. 91A 132-9