Tellimagrandin I, HCV invasion inhibitor from Rosae Rugosae Flos

Bioorganic and Medicinal Chemistry Letters

Volumn 20, Issue 5, 2010, Pages 1598-1600

  Tamura, Satoru ^a   Yang, Gang Ming ^a   Yasueda, Natsuko ^a   Matsuura, Yoshiharu ^b   Komoda, Yasumasa ^b   Murakami, Nobutoshi ^a  

^a OSAKA UNIVERSITY   (Japan)

^b OSAKA UNIVERSITY   (Japan)

Author keywords

Envelope protein E1, E2; HCV; Invasion inhibitor; Rosa rugosa Thunb.; Tellimagrandin I

Indexed keywords

1,2,3,4,6 O PENTAGALLOYL BETA DEXTRO GLUCOSE; 2,3,4,6 O TETRAGALLOYL DEXTRO GLUCOSE; 3,4,5 O TRIBENZYLGALLIC ACID; ANTIVIRUS AGENT; CASUARICTIN; EUGENIIN; GALLIC ACID DERIVATIVE; GLUCOSE DERIVATIVE; GLYCOPROTEIN E1; GLYCOPROTEIN E2; METHANOL; PEDUNCULAGIN; TANNIN DERIVATIVE; TELLIMAGRANDIN I; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANTIVIRAL ACTIVITY; ARTICLE; BIOASSAY; CONTROLLED STUDY; CRYSTAL STRUCTURE; DRUG INHIBITION; DRUG POTENCY; DRUG SYNTHESIS; HEPATITIS C VIRUS; MEDICINAL PLANT; NONHUMAN; PROTEIN EXPRESSION; ROSA RUGOSA; ROSE; STRUCTURE ACTIVITY RELATION; VIRUS REPLICATION;

ANTIVIRAL AGENTS; BIPHENYL COMPOUNDS; GALLIC ACID; GLUCOSIDES; HUMANS; ROSACEAE; STRUCTURE-ACTIVITY RELATIONSHIP; VIRAL ENVELOPE PROTEINS; VIRUS INTEGRATION;

FLOS; HEPATITIS C VIRUS; ROSA RUGOSA;

EID: 76649102400     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2010.01.084     Document Type: Article

References (18)

1. Lohmann V., Korner F., Koch J.-O., Herian U., Theilmann L., and Bartenschlager R. Science 285 (1999) 110
2. Shepard C.W., Finelli L., and Alter M.J. Lancet Infect. Dis. 5 (2005) 558
3. Fried M.W., Shiffman M.L., Reddy K.R., Smith C., Marinos G., Goncales Jr. F.L., Haussinger D., Daigo M., Carosi G., Dhumeaux D., Craxi A., Lin A., Hoffman J., and Yu J. N. Eng. J. Med. 347 (2002) 975
4. Thompson A.J.V., and McHutchison J.G. Aliment. Pharmacol. Ther. 29 (2009) 689
5. Matsuura Y., Tani H., Suzuki K., Kimura-Someya T., Suzuki R., Aizaki H., Ishii K., Moriishi K., Robison C.S., Whitt M.A., and Miyamura T. Virology 286 (2001) 263
6. 2 atmosphere for 1 h, the E1E2 virus or G* virus suspension (10 μL) was inoculated. The cells were further incubated for 24 h, then SEAP activities in supernatants were evaluated by use of Great EscAPe SEAP Fluorescent Detection kit (BD Biosciences). Lactoferrin was used as the positive control for the assay and showed about 45% inhibition at the concentration of 30 μg/mL.
7. Okuda T., Yoshida T., Hatano T., Koga T., Toh N., and Kuriyama K. Tetrahedron Lett. 23 (1982) 3937
8. Lee S., Tanaka T., Nonaka G., and Nishioka I. Phytochemistry 29 (1990) 3621
9. Feldman K., Ensel S., and Minard R. J. Am. Chem. Soc. 116 (1994) 1742
10. Yoshida T., Haba K., Arata R., Nakato F., Singu T., and Okuda T. Chem. Pharm. Bull. 43 (1995) 1101
11. Nishio T., and Omote Y. J. Chem. Soc., Perkin Trans. I (1983) 1765
12. Spencer C.M., Cai Y., Martin R., Lilley T.H., and Haslam E. J. Chem. Soc., Perkin Trans. II 4 (1990) 651
13. Fukuda T., Ito H., and Yoshida T. Phytochemistry 63 (2003) 795
14. Karamali K., and Kerstin L. Tetrahedron 53 (1997) 10725
15. Zang H., Rothwangl K., Mesecar A.D., Sabahi A., Rong L., and Fong H.H.S. J. Nat. Prod. 72 (2009) 2158
16. Takebe. Y.; Hakamada, W.; Uenishi, R. Jpn. Kokai Tokkyo Koho JP2009215280, 2009.
17. Cuthbertson, T. J.; Ibamez, M.; Rijnbrand, C. A.; Jackson, A. J.; Mittapalli, G. K.; Zhao, F.; MacDonald, J. E.; Wong-Staal, F. PCT Int. Appl. WO2008021745, 2008.
18. Takada A., Robison C., Goto H., Sanchez A., Murti K.G., Whitt M.A., and Kawaoka Y. Proc. Natl. Acad. Sci. U.S.A. 94 (1997) 14764