Research on alcohol and adolescent brain development: Opportunities and future directions

Alcohol

Volumn 44, Issue 1, 2010, Pages 119-124

  Witt, Ellen D ^a,b,c  

^a NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM   (United States)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

^c U S DEPARTMENT OF HEALTH AND HUMAN SERVICES   (United States)

Author keywords

Adolescent; Alcohol; Brain development

Indexed keywords

4 AMINOBUTYRIC ACID RECEPTOR; ALCOHOL; BRAIN DERIVED NEUROTROPHIC FACTOR; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; N METHYL DEXTRO ASPARTIC ACID RECEPTOR;

ADOLESCENT; ADOLESCENT DEVELOPMENT; ALCOHOL ABUSE; ALCOHOL CONSUMPTION; ALCOHOL INTOXICATION; ALCOHOL TOLERANCE; ALCOHOLISM; BRAIN DEVELOPMENT; DOPAMINE METABOLISM; DRINKING BEHAVIOR; GABAERGIC TRANSMISSION; GENETIC VARIABILITY; HUMAN; LONG TERM POTENTIATION; MESOLIMBIC DOPAMINERGIC SYSTEM; NERVE CELL NETWORK; NERVE CELL PLASTICITY; NEUROIMAGING; NEUROTOXICITY; NEUROTRANSMISSION; NONHUMAN; PREFRONTAL CORTEX; REVIEW;

ADOLESCENT; ADOLESCENT BEHAVIOR; ADOLESCENT DEVELOPMENT; ALCOHOL DRINKING; ALCOHOL-INDUCED DISORDERS, NERVOUS SYSTEM; ANIMALS; BIOMEDICAL RESEARCH; BRAIN; CENTRAL NERVOUS SYSTEM DEPRESSANTS; COGNITION; ETHANOL; HUMANS; MODELS, ANIMAL; NEURONS;

ANIMALIA;

EID: 76549096892     PISSN: 07418329     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.alcohol.2009.08.011     Document Type: Review

References (84)

1. Abate P., Pueta M., Spear N.E., Molina J.C. Fetal learning about ethanol and later ethanol responsiveness: evidence against " safe" amounts of prenatal exposure. Exp. Biol. Med. 2008, 233:139-154.
2. Acheson S.K., Richardson R., Swartzwelder H.S. Developmental changes in seizure susceptibility during ethanol withdrawal. Alcohol 1999, 18:23-26.
3. Alcohol and development in youth: a multidisciplinary overview. Alcohol Res. Health 2004/2005, 28:105-176.
4. Andersen S.L., Dumont N.L., Teicher M.H. Developmental differences in dopamine synthesis inhibition by (+)-7-OH-DPAT. Naunyn Schmeidebergs Arch. Pharmacol. 1997, 356:173-181.
5. Andersen S.L., Thompson A.T., Rutstein M., Hostetter J.C., Teicher M.H. Dopamine receptor pruning in prefrontal cortex during the periadolescent period in rats. Synapse 2000, 37:167-169.
6. Bachman J.G., O'Malley P.M., Schulenberg J.E., Johnston L.D., Bryant A.L., Merline A.G. The Decline of Substance Use in Young Adulthood: Changes in Social Activities, Roles, and Beliefs 2002, Lawrence Erlbaum Associates, Inc, Mawah, NJ.
7. Badanich K.A., Maldonado A.M., Kirstein C.L. Chronic ethanol exposure during adolescence increases basal dopamine in the nucleus accumbens septi during adulthood. Alcohol. Clin. Exp. Res. 2007, 31:895-900.
8. Blakemore S., Choudhury S. Development of the adolescent brain: implications for executive function and social cognition. J. Child Psychol. Psychiatr. 2006, 47:296-312.
9. Bourgeois J.P., Goldman-Rakic P.S., Rakic P. Synaptogenesis in the prefrontal cortex of rhesus monkeys. Cereb. Cortex 1994, 4:78-96.
10. Breese G.R., Overstreet D.H., Knapp D.J., Navarro M. Prior multiple ethanol withdrawals enhance stress-induced anxiety-like behavior: inhibition by CRF1- and benzodiazepine receptor antagonists and a 5-HT1A-receptor agonist. Neuropsychopharmacology 2005, 30:1662-1669.
11. Brenhouse H.C., Sonntag K.C., Andersen S.L. Transient D1 dopamine receptor expression on prefrontal cortex projection neurons: relationship to enhanced motivational salience of drug cues in adolescence. J. Neurosci. 2008, 28:2375-2382.
12. Carpenter-Hyland E.P., Chandler L.J. Adaptive plasticity of NMDA receptors and dendritic spines: implications for enhanced vulnerability of the adolescent brain to alcohol addiction. Pharmacol. Biochem. Behav. 2007, 86:200-208.
13. Chen K., Kandel D.B. The natural history of drug use from adolescence to mid-thirties in a general population sample. Am. J. Public Health 1995, 85:41-47.
14. Clark D.B., Thatcher D.L., Tapert S.F. Alcohol, psychological dysregulation, and adolescent brain development. Alcohol. Clin. Exp. Res. 2008, 32:375-385.
15. Crews F., June H., Hodge C. Adolescent cortical development: a critical period of vulnerability to addiction. Pharmacol. Biochem. Behav. 2007, 86:189-199.
16. Crews F.T., Braun C.J., Hoplight B., Switzer R.C., Knapp D.J. Binge ethanol consumption causes differential brain damage in young adolescent rats compared with adult rats. Alcohol. Clin. Exp. Res. 2000, 24:1712-1723.
17. Crews F.T., Collins M.A., Dlugos C., Littleton J., Wilkins L., Neafsey E.J., et al. Alcohol-induced neurodegeneration: when, where, and why?. Alcohol. Clin. Exp. Res. 2004, 28:350-364.
18. Crews F.T., Mdzinarishvili A., Kim D., He J., Nixon K. Neurogenesis in adolescent brain is potently inhibited by ethanol. Neuroscience 2006, 137:437-445.
19. Criado J.R., Wills D.N., Walker B.M., Ehlers C.L. Electrophysiological effects of dizocilpine (MK-801) in adult rats exposed to ethanol during adolescence. Alcohol. Clin. Exp. Res. 2008, 32:1752-1762.
20. Cunningham M.G., Bhattacharyya S., Benes F.M. Amygdalo-cortical sprouting continues into early adulthood: implications for the development of normal and abnormal function during adolescence. J. Comp. Neurol. 2002, 453:116-130.
21. Cunningham M.G., Bhattacharyya S., Benes F.M. Increasing interaction of amygdalar afferents with GABAergic interneurons between birth and adulthood. Cereb. Cortex 2008, 18:1529-1535.
22. De Bellis M.D., Clark D.B., Beers S.R., Soloff P., Boring A.M., Hall J., et al. Hippocampal volume in adolescent onset alcohol use disorders. Am. J. Psychiatry 2000, 157:737-744.
23. De Bellis M.D., Narasimhan A., Thatcher D.L., Keshavan M.S., Soloff P., Clark D.B. Prefrontal cortex, thalamus, and cerebellar volumes in adolescent onset alcohol use disorders. Alcohol. Clin. Exp. Res. 2005, 29:1590-1600.
24. De Bellis M.D., Van Voorhees E., Hooper S.R., Gibler N., Nelson L., Hege S.G., et al. Diffusion tensor imaging measures of the corpus callosum in adolescents with adolescent onset alcohol use disorders. Alcohol. Clin. Exp. Res. 2008, 32:395-404.
25. Donovan J.E., Jessor R., Jessor L. Problem drinking in adolescence and young adulthood: a follow-up study. J. Stud. Alcohol 1983, 44:109-137.
26. Dormeus T.L., Brunell S.C., Varlinskaya E.I., Spear L.P. Anxiogenic effects during withdrawal from acute ethanol in adolescent and adult rats. Pharmacol. Biochem. Behav. 2003, 75:411-418.
27. Fleming R.L., Wilson W.A., Swartzwelder H.S. Magnitude and ethanol sensitivity of tonic GABAA receptor-mediated inhibition in dentate gyrus changes from adolescence to adulthood. J. Neurophysiol. 2007, 97:3806-3811.
28. Recent Developments in Alcoholism. Alcohol Problems in Adolescents and Young Adults: Epidemiology, Neurobiology, Prevention, Treatment 2005, Vol. 17. Kkywer/acadenuc/Plenum Publishers, New York, NY. M. Galanter (Ed.).
29. Giedd J.N., Blumenthal J., Jeffries N.O., Castellanos F.X., Liu H., Zijdenbos A., et al. Brain development during childhood and adolescence: a longitudinal MRI study. Nat. Neurosci. 1999, 2:861-863.
30. Grant B.F., Dawson D.A. Age at onset of alcohol use and its association with DSM-IV alcohol abuse and dependence: results from the National Longitudinal Alcohol Epidemiological Survey. J. Subst. Abuse 1997, 9:103-110.
31. Grant B.F., Harford T.C., Grigson M.B. Stability of alcohol consumption among youth: a national longitudinal study. J. Stud. Alcohol 1988, 49:253-260.
32. Green A.E., Munafo M.R., DeYoung C.G., Fossella J.A., Fan J., Gray J.R. Using genetic data in cognitive neuroscience: from growing pains to genuine insights. Nat. Rev. Neurosci. 2008, 9:710-720.
33. Honey P.L., Galef B.G. Ethanol consumption by rat dams during gestation, lactation and weaning increases ethanol consumption by their adolescent young. Dev. Psychobiol. 2003, 42:252-260.
34. Huttenlocher P.R. Synaptic density in human frontal cortex-developmental changes and effects of aging. Brain Res. 1979, 163:195-205.
35. Huttenlocher P.R. Synapse elimination and plasticity in developing human cerebral cortex. Am. J. Ment. Defic. 1984, 88:488-496.
36. Insel T.R., Miller L.P., Gelhard R.E. The ontogeny of excitatory amino acid receptors in rat forebrain-I. N-methyl-D-aspartate and quisqualate receptors. Neuroscience 1990, 35:31-43.
37. Johnston L.D., O'Malley P.M., Bachman J.G., Schulenberg J.E. Monitoring the Future National Results on Adolescent Drug Use: Overview of Key Findings, 2008 2009, NIH Publication No. 09-7401, National Institute on Drug Abuse, Bethesda, MD.
38. Kalsbeek A., Voorn P., Buijs R.M., Pool C.W., Uylings H.B. Development of the dopaminergic innervation in the prefrontal cortex of the rat. J. Comp. Neurol. 1988, 269:58-72.
39. Knapp D.J., Overstreet D.H., Moy S.S., Breese G.R. SB242084, flumazenil, and CRA1000 block ethanol withdrawal-induced anxiety. Alcohol 2004, 32:101-111.
40. Lambe E.K., Krimer L.S., Goldman-Rakic P.S. Differential postnatal development of catecholamine and serotonin inputs to identified neurons in prefrontal cortex of rhesus monkey. J. Neurosci. 2000, 20:8780-8787.
41. Lewis D.A. Development of the prefrontal cortex during adolescence: insights into vulnerable neural circuits in schizophrenia. Neuropsychopharmacology 1997, 16:385-398.
42. Li Q., Wilson W.A., Swartzwelder H.S. Developmental differences in the sensitivity of hippocampal GABAA receptor-mediated IPSCs to ethanol. Alcohol. Clin. Exp. Res. 2003, 27:2017-2022.
43. Li Q., Wilson W.A., Swartzwelder H.S. Developmental differences in the sensitivity of spontaneous and miniature IPSCs to ethanol. Alcohol. Clin. Exp. Res. 2006, 30:119-126.
44. Li T.K., Hewitt B.G., Grant G.F. Is there a future for quantifying drinking in the diagnosis, treatment, and prevention of alcohol use disorders?. Alcohol. Clin. Exp. Res. 2007, 41:57-63.
45. Little P.J., Kuhn C.M., Wilson W.A., Swartzwelder H.S. Differential effects of ethanol in adolescent and adult rats. Alcohol. Clin. Exp. Res. 1996, 20:1346-1351.
46. Markham J.A., Morris J.R., Juraska J.M. Neuron number decreases in the rat ventral, but not dorsal medial prefrontal cortex between adolescence and adulthood. Neuroscience 2007, 144:961-968.
47. Markwiese B.J., Acheson S.K., Levin E.D., Wilson W.A., Swartzwelder H.S. Differential effects of ethanol on memory in adolescent and adult rats. Alcohol. Clin. Exp. Res. 1998, 22:416-422.
48. McDonald J.W., Johnston M.V., Young A.B. Differential ontogenetic development of three receptors comprising the NMDA receptor/channel complex in the rat hippocampus. Exp. Neurol. 1990, 110:237-247.
49. McQueeny B.C., Schweinsburg A.D., Jacobus J., Bava S., Frank L.R., Tapert S.F. Altered white matter integrity in adolescent binge drinkers. Alcohol. Clin. Exp. Res. 2009, 33:1278-1285.
50. Medina K.L., Schweinsburg A.D., Cohen-Zion M., Nagel G.J., Tapert S.F. Effects of alcohol and combined marijuana and alcohol use during adolescence on hippocampal volume and asymmetry. Neurotoxicol. Teratol. 2007, 29:141-152.
51. Monti P.M., Miranda R., Nixon K., Sher K.J., Swartzwelder H.S., Tapert S.F., et al. Adolescence: booze, brains, and behavior. Alcohol. Clin. Exp. Res. 2005, 29:207-220.
52. Nagel B.J., Schweinsburg A.D., Phan V., Tapert S.F. Reduced hippocampal volume among adolescents with alcohol use disorders without psychiatric comorbidity. Psychiatry Res. 2005, 139:181-190.
53. Overstreet D.H., Knapp D.J., Moy S.S., Breese G.R. A 5-HT1A agonist and a 5HT2c antagonist reduce social interaction deficit induced by multiple ethanol withdrawals in rats. Psychopharmacology 2003, 167:344-352.
54. Pascual M., Blanco A.M., Cauli O., Minarro J., Guerri C. Intermittent ethanol exposure induces inflammatory brain damage and causes long-term behavioural alterations in adolescent rats. Eur. J. Neurosci. 2007, 25:541-550.
55. Pascual M., Boix J., Felipo V., Guerri C. Repeated alcohol administration during adolescence causes changes in the mesolimbic dopaminergic and glutamatergic systems and promotes alcohol intake in the adult rat. J. Neurochem. 2009, 108:920-931.
56. Pepino M.Y., Abate P., Spear N.E., Molina J.C. Heightened ethanol intake in infant and adolescent rats after nursing experiences with an ethanol-intoxicated dam. Alcohol. Clin. Exp. Res. 2004, 28:895-905.
57. Ponce L.F., Pautassi R.M., Spear N.E., Molina J.C. Nursing from an ethanol-intoxicated dam induces short-and long-term disruptions in motor performance and enhances later self-administration of the drug. Alcohol. Clin. Exp. Res. 2004, 28:1039-1050.
58. Ponce L.F., Pautassi R.M., Spear N.E., Molina J.C. Ethanol-mediated operant learning in the infant rat leads to increased ethanol intake during adolescence. Pharmacol. Biochem. Behav. 2008, 90:640-650.
59. Rakic P., Bourgeois J.P., Goldman-Rakic P.S. Synaptic development of the cerebral cortex: implications for learning, memory, and mental illness. Progress in Brain Research 1994, Vol. 102:227-243. Elsevier Science, Amsterdam. J. van Pelt, M.A. Corner, H.B.M. Uylings, F.H. Lopes da Silva (Eds.).
60. Sahr A.E., Thielen R., Lumeng L., Li T.-K., McBride W.J. Long-lasting alterations of the mesolimbic dopamine system after periadolescent ethanol drinking by alcohol-preferring rats. Alcohol. Clin. Exp. Res. 2004, 28:702-711.
61. Schwandt M.L., Higley J.D., Suomi S.J., Heilig M., Barr C.S. Rapid tolerance and locomotor sensitization in ethanol naïve adolescent rhesus macaques. Alcohol. Clin. Exp. Res. 2008, 32:1217-1228.
62. Silveri M.M., Spear L.P. Decreased sensitivity to the hypnotic effects of ethanol early in ontogeny. Alcohol. Clin. Exp. Res. 1998, 22:670-676.
63. Silveri M.M., Spear L.P. Acute, rapid, and chronic tolerance during ontogeny: observations when equating ethanol perturbation across age. Alcohol. Clin. Exp. Res. 2001, 23:1301-1308.
64. Silveri M.M., Spear L.P. The effects of NMDA and GABAA pharmacological manipulations on ethanol sensitivity in immature and mature animals. Alcohol. Clin. Exp. Res. 2002, 26:449-456.
65. Silveri M.M., Spear L.P. The effects of NMDA and GABAA pharmacological manipulations on acute and rapid tolerance to ethanol during ontogeny. Alcohol. Clin. Exp. Res. 2004, 28:884-894.
66. Sircar R., Basak A.K., Sircar D. Repeated ethanol exposure affects the acquisition of spatial memory in adolescent female rats. Behav. Brain. Res. 2009, 202:225-231.
67. Sircar R., Sircar D. Adolescent rats exposed to repeated ethanol treatment show lingering behavioral impairments. Alcohol. Clin. Exp. Res. 2005, 29:1402-1410.
68. Sisk C.L., Zehr J.L. Pubertal hormones organize the adolescent brain and behavior. Front. Neuroendocrinol. 2005, 26:163-174.
69. Sowell E.R., Thompson P.M., Holmes C.J., Batth R., Jernigan T.L., Toga A.W. Localizing age-related changes in brain structure between childhood and adolescence using statistical parametric mapping. NeuroImage 1999, 6:587-597.
70. Spear L.P. The adolescent brain and age-related behavioral manifestations. Neurosci. Biobehav. Rev. 2000, 24:417-463.
71. Squeglia L.M., Jacobus J., Tapert S.F. The influence of substance use on adolescent brain development. Clin. EEG Neurosci. 2009, 40:31-38.
72. Steinberg L. Cognitive and affective development in adolescence. Trends Cogn. Sci. 2005, 9:69-74.
73. Swartzwelder H.S., Richardson R.C., Markwiese-Foerch B., Wilson W.A., Little P.J. Developmental differences in the acquisition of tolerance to ethanol. Alcohol 1998, 15:311-314.
74. Tarazi F.I., Baldessarini R.J. Comparative postnatal development of dopamine D1, D2, and D4 receptors in rat forebrain. Int. J. Dev. Neurosci. 2000, 18:29-37.
75. Teicher M.H., Andersen S.L., Hostetter J.C. Evidence for dopamine receptor pruning between adolescence and adulthood in striatum but not nucleus accumbens. Dev. Brain Res. 1995, 89:167-172.
76. Temple M.T., Fillmore K.M. The variability of drinking patterns and problems among young men age 16-31: a longitudinal study. Int. J. Addict. 1985-1986, 20:1595-1620.
77. Varlinskaya E.E., Spear L.P. Acute ethanol withdrawal withdrawal (hangover) and social behavior in adolescent and adult male and female Sprague-Dawley rats. Alcohol. Clin. Exp. Res. 2004, 28:40-50.
78. Vetter C.S., Doremus-Fitzwater T.L., Spear L.P. Time course of elevated ethanol intake in adolescent relative to adult rats under continuous, voluntary-access conditions. Alcohol. Clin. Exp. Res. 2007, 31:1159-1168.
79. White A.M., Swartzwelder H.S. Age-related effects of alcohol on memory and memory-related brain function in adolescents and adults. Alcohol Problems in Adolescents and Young Adults 2005, Vol. 17:161-176. Kluwer Academic/Plenum Publishers, New York. M. Galanter (Ed.).
80. Wills T.A., Knapp D.J., Overstreet D.H., Breese G.R. Differential dietary ethanol intake and blood ethanol levels in adolescent and adult rats: effects on anxiety-like behavior and seizure thresholds. Alcohol. Clin. Exp. Res. 2008, 32:1350-1360.
81. Wills T.A., Knapp D.J., Overstreet D.H., Breese G.R. Sensitization, duration, and pharmacological blockade of anxiety-like behavior following repeated ethanol withdrawal in adolescent and adult rats. Alcohol. Clin. Exp. Res. 2009, 33:455-463.
82. Witt E.D. Mechanisms of alcohol abuse and alcoholism in adolescents: a case for developing animal models. Behav. Neural Biol. 1994, 62:168-177.
83. Yakovlev P.A., Lecours I.R. The myelogenetic cycles of regional maturation of the brain. Regional Development of the Brain in Early Life 1967, 3-70. Blackwell, Oxford. A. Minkowski (Ed.).
84. Yan H., Li Q., Fleming R., Madison R.D., Wilson W.A., Swartzwelder H.S. Development sensitivity of hippocampal interneurons to ethanol: involvement of the hyperpolarization-activated current Ih. J. Neurophysiol. 2009, 101:67-83.