The interplay of membrane formation and drug release in solution-cast films of polylactide polymers

International Journal of Pharmaceutics

Volumn 388, Issue 1-2, 2010, Pages 1-12

  Ma, Decheng ^a   McHugh, Anthony J ^a  

^a Lehigh University   (United States)

Author keywords

Biodegradable; Controlled release; Drug delivery; Membrane; Phase inversion

Indexed keywords

NAPROXEN; POLYGLACTIN; POLYLACTIDE; POLYMER; SOLVENT;

ARTICLE; CHEMICAL INTERACTION; CHEMICAL STRUCTURE; CRYSTALLIZATION; DRUG RELEASE; DRUG SOLUBILITY; DRUG STABILITY; HUMIDITY; POROSITY; PRIORITY JOURNAL; SYNTHESIS; THERMODYNAMICS;

CHEMISTRY, PHARMACEUTICAL; CRYSTALLIZATION; DELAYED-ACTION PREPARATIONS; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; HUMIDITY; NAPROXEN; POLYESTERS; POLYGLACTIN 910; POLYMERS; POROSITY; SOLUBILITY; SOLVENTS;

EID: 76549088763     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2009.12.027     Document Type: Article

References (19)

1. Alexis F. Factors affecting the degradation and drug-release mechanism of poly (lactic acid) and poly [(lactic acid-co-(glycolic acid)]. Polym. Int. 54 (2005) 36-46
2. Bird R.B., Stewart W.E., and Lightfoot E.N. Transport Phenomena. 2nd ed. (2002), Wiley, New York p. 529
3. Brodbeck K.J., DesNoyer J.R., and McHugh A.J. Phase inversion dynamics of PLGA solutions related to drug delivery. Part II. The role of solution thermodynamics and bath side mass transfer. J. Control. Rel. 62 (1999) 333-344
4. Crank J. The Mathematics of Diffusion (1975), Oxford, London pp. 47-48
5. Herbig S.M., Cardinal J.R., Korsmeyer R.W., and Smith K.L. Asymmetric-membrane tablet coatings for osmotic drug delivery. J. Control. Rel. 35 (1995) 127-136
6. Kumar N.G. Viscosity-molecular weight-temperature-shear rate relationships of polymer melts: a literature review. J. Polym. Sci.: Macromol. Rev. 15 (1980) 255-325
7. Li S.M., Garreau H., and Vert M. Structure-property relationships in the case of the degradation of massive aliphatic poly (α-hydroxy acids) in aqueous media. Part 1. Poly (dl-lactic acid). J. Mater. Sci.: Mater. Med. 1 (1990) 123-130
8. Li S.M., Garreau H., and Vert M. Structure-property relationships in the case of the degradation of massive aliphatic poly (α-hydroxy acids) in aqueous media. Part 2. Degradation of lactide-glycolide copolymers: PLA37. 5GA25 and PLA75GA25. J. Mater. Sci.: Mater. Med. 1 (1990) 131-139
9. Li S.M., Garreau H., and Vert M. Structure-property relationships in the case of the degradation of massive aliphatic poly (α-hydroxy acids) in aqueous media. Part 3. Influence of the morphology of poly (l-lactic acid). J. Mater. Sci.: Mater. Med. 1 (1990) 198-206
10. Li J., Masso J.J., and Guertin J.A. Prediction of drug solubility in an acrylate adhesive based on the drug-polymer interaction parameter and drug solubility in acetonitrile. J. Control. Rel. 83 (2002) 211-221
11. Liu H.C., Lee I.C., Wang J.H., Yang S.H., and Young T.H. Preparation of PLLA membranes with different morphologies. Biomaterials 25 (2004) 4047-4056
12. Ma D., and McHugh A.J. The interplay of phase inversion and membrane formation in the drug release characteristics of a membrane-based delivery system. J. Membr. Sci. 298 (2007) 211-290
13. Ma, D., 2008. The interplay of drug, polymer and solvent properties in the fabrication of membrane-based delivery systems. Ph.D. Thesis. Lehigh University, Bethlehem, PA.
14. Mohamed F., and van der Walle C.F. Engineering biodegradable polyester particles with specific drug targeting and drug release properties. J. Pharm. Sci. 97 (2008) 71-87
15. Nair R., Nyamweya N., Gönen S., Martinez-Miranda L.J., and Hoag S.W. Influence of various drugs on the glass transition temperature of poly (vinyl pyrrolidone): a thermodynamic and spectroscopic investigation. Int. J. Pharm. 225 (2001) 83-96
16. Stamatialis D.F., Papenburg B.J., Girońes M., Saiful M.S., Bettahalli S.N.M., Schmitmeier S., and Wessling M. Medical applications of membranes: drug delivery, artificial organs and tissue engineering. J. Membr. Sci. 308 (2008) 1-34
17. van de Witte P., Dijkstra P.J., van den Berg J.W.A., and Feijen J. Phase behavior of polylactides in solvent-nonsolvent mixtures. J. Polym. Sci., Part B: Polym. Phys. 34 (1996) 2553-2568
18. van de Witte P., Esselbrugge H., Dijkstra P.J., van den Berg J.W.A., and Feijen J. Phase transitions during membrane formation of polylactides. I. A morphological study of membranes obtained from the system polylactide-chloroform-methanol. J. Membr. Sci. 113 (1996) 223-236
19. g biodegradable polymer. J. Membr. Sci.