Gynaecologic cancer complicating pregnancy: An overview

Best Practice and Research: Clinical Obstetrics and Gynaecology

Volumn 24, Issue 1, 2010, Pages 61-79

  Amant, Frédéric ^a   Brepoels, Lieselot ^a   Halaska, Michael J ^b   Gziri, Mina Mhallem ^c   Calsteren, Kristel Van ^a  

^a UNIVERSITY HOSPITALS LEUVEN   (Belgium)

^b CHARLES UNIVERSITY   (Czech Republic)

^c UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

Author keywords

cancer; chemotherapy; neonatal; pregnancy; radiotherapy; surgery

Indexed keywords

ANTHRACYCLINE; BETAMETHASONE; BLEOMYCIN; CARBOPLATIN; CISPLATIN; CYCLOPHOSPHAMIDE; DEXAMETHASONE; DOCETAXEL; DOXORUBICIN; EPIRUBICIN; ETOPOSIDE; FLUORODEOXYGLUCOSE F 18; GADOLINIUM; GENTAMICIN; IDARUBICIN; IMIQUIMOD; IODINATED CONTRAST MEDIUM; MACROSALB TC 99M; MEDRONATE TECHNETIUM TC 99M; NAVELBINE; PACLITAXEL; PLATINUM DERIVATIVE; TECHNETIUM 99M; TRASTUZUMAB;

ABSENCE OF SIDE EFFECTS; ADNEXA DISEASE; ALOPECIA; BONE MARROW SUPPRESSION; BRAIN ATROPHY; BRAIN VENTRICLE DILATATION; BREAST CANCER; CANCER CHEMOTHERAPY; CANCER DIAGNOSIS; CANCER INCIDENCE; CANCER RADIOTHERAPY; CANCER STAGING; CANCER SURGERY; CANCER THERAPY; CAPILLARY LEAK SYNDROME; CARDIOTOXICITY; COMPUTER ASSISTED TOMOGRAPHY; CONGENITAL MALFORMATION; CONGESTIVE CARDIOMYOPATHY; DRUG HALF LIFE; DRUG MECHANISM; DRUG MEGADOSE; DYSGERMINOMA; ECHOGRAPHY; ENDOMETRIUM CANCER; FEMALE; FETUS DEATH; FETUS RISK; GERM CELL TUMOR; GYNECOLOGIC CANCER; HEARING IMPAIRMENT; HEARING LOSS; HUMAN; HYDROCEPHALUS; HYPOTHYROIDISM; INTERDISCIPLINARY COMMUNICATION; LAPAROSCOPY; LONG TERM CARE; MATERNAL CARE; NEUROBLASTOMA; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; NUCLEAR MEDICINE; OLIGOHYDRAMNIOS; OUTCOMES RESEARCH; OVARY CANCER; OXYGENATION; PATIENT MONITORING; PATIENT SAFETY; PERCEPTION DEAFNESS; PLACENTA CIRCULATION; PREGNANCY; PREGNANCY TERMINATION; PREMATURE LABOR; PREMATURITY; PRENATAL EXPOSURE; PRIORITY JOURNAL; PROGNOSIS; RADIATION EXPOSURE; RADIOBIOLOGY; RADIODIAGNOSIS; RESPIRATORY DISTRESS SYNDROME; RESPIRATORY FAILURE; REVIEW; SECOND TRIMESTER PREGNANCY; SEPSIS; SPONTANEOUS ABORTION; SURGICAL TECHNIQUE; TERATOGENESIS; THERAPY DELAY; THIRD TRIMESTER PREGNANCY; THYROID CANCER; UTERINE CERVIX CANCER; VULVA CANCER;

ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; BREAST NEOPLASMS; CHEMOTHERAPY, ADJUVANT; ENDOMETRIAL NEOPLASMS; FEMALE; GENITAL NEOPLASMS, FEMALE; HUMANS; NEOPLASM STAGING; OVARIAN NEOPLASMS; PREGNANCY; PREGNANCY COMPLICATIONS, NEOPLASTIC; RADIOTHERAPY, ADJUVANT; TREATMENT OUTCOME; UTERINE CERVICAL NEOPLASMS; VULVAR NEOPLASMS;

EID: 76449120543     PISSN: 15216934     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bpobgyn.2009.08.001     Document Type: Review

References (164)

1. Cardonick E., and Iacobucci A. Use of chemotherapy during human pregnancy. Lancet Oncol 5 (2004) 283-291
2. Kal H.B., and Struikmans H. Radiotherapy during pregnancy: fact and fiction. Lancet Oncol 6 (2005) 328-333
3. Stensheim H., Moller B., van Dijk T., et al. Cause-specific survival for women diagnosed with cancer during pregnancy or lactation: a registry-based cohort study. J Clin Oncol 27 (2009) 45-51
4. Pavlidis N.A. Coexistence of pregnancy and malignancy. Oncologist 7 (2002) 279-287
5. Pereg D., Koren G., and Lishner M. Cancer in pregnancy: gaps, challenges and solutions. Cancer Treat Rev 34 (2008) 302-312
6. Bergonie J., and Tribondeau L. De quelques resultants de la radiotherapy, et esaie de fixation d'une technique rationelle. Comptes Rendu des Seances de l'Academie des Sciences 143 (1906) 983-985
7. Ratnapalan S., Bona N., Chandra K., et al. Physicians' perceptions of teratogenic risk associated with radiography and CT during early pregnancy. AJR Am J Roentgenol 182 (2004) 1107-1109
8. Damilakis J. Pregnancy and diagnostic X-rays. Eur Radiol Syllabus 14 (2004) 33-39
9. Available at. www.icrp.org
10. Stabin M., Watson E., Cristy M., et al. Mathematical models and specific absorbed fractions of photon energy in the non-pregnant adult female and at the end of each trimester of pregnancy. Report ORNL/TM-12907 (1995), Oak Ridge National Laboratory, Oak Ridge, TN
11. Russell J.R., Stabin M.G., Sparks R.B., et al. Radiation absorbed dose to the embryo/fetus from radiopharmaceuticals. Health Phys 73 (1997) 756-769
12. Nuclear medicine resources manual (2006), International Atomic Energy Agency, Vienna STI/PUB/1198 ISBN 92-0-107504-9
13. Stabin M.G., and Breitz H.B. Breast milk excretion of radiopharmaceuticals: mechanisms, findings, and radiation dosimetry. J Nucl Med 41 (2000) 863-873
14. Available at:. http://rpop.iaea.org/RPOP/RPoP/Content/SpecialGroups/1_PregnantWomen/index.htm
15. Nagayama M., Watanabe Y., Okumura A., et al. Fast MR imaging in obstetrics. Radiographics 22 (2002) 563-580
16. Stubbe P., Heidemann P., Schurnbrand P., et al. Transient congenital hypothyroidism after amniofetography. Eur J Pediatr 135 (1980) 97-99
17. Webb J.A., Thomsen H.S., and Morcos S.K. The use of iodinated and gadolinium contrast media during pregnancy and lactation. Eur Radiol 15 (2005) 1234-1240
18. Woo S.Y., Fuller L.M., Cundiff J.H., et al. Radiotherapy during pregnancy for clinical stages IA-IIA Hodgkin's disease. Int J Radiat Oncol Biol Phys 23 (1992) 407-412
19. Stovall M., Blackwell C.R., Cundiff J., et al. Fetal dose from radiotherapy with photon beams: report of AAPM Radiation Therapy Committee Task Group No. 36. Med Phys 22 (1995) 63-82
20. Ni Mhuireachtaigh R., and O'Gorman D.A. Anesthesia in pregnant patients for nonobstetric surgery. J Clin Anesth 18 (2006) 60-66
21. Moran B.J., Yano H., Al Zahir N., et al. Conflicting priorities in surgical intervention for cancer in pregnancy. Lancet Oncol 8 (2007) 536-544
22. Cohen-Kerem R., Railton C., Oren D., et al. Pregnancy outcome following non-obstetric surgical intervention. Am J Surg 190 (2005) 467-473
23. Jackson H., Granger S., Price R., et al. Diagnosis and laparoscopic treatment of surgical diseases during pregnancy: an evidence-based review. Surg Endosc 22 (2008) 1917-1927
24. Rizzo A.G. Laparoscopic surgery in pregnancy: long-term follow-up. J Laparoendosc Adv Surg Tech A 13 (2003) 11-15
25. Mathevet P., Nessah K., Dargent D., et al. Laparoscopic management of adnexal masses in pregnancy: a case series. Eur J Obstet Gynecol Reprod Biol 108 (2003) 217-222
26. Yuen P.M., Ng P.S., Leung P.L., et al. Outcome in laparoscopic management of persistent adnexal mass during the second trimester of pregnancy. Surg Endosc 18 (2004) 1354-1357
27. Affleck D.G., Handrahan D.L., Egger M.J., et al. The laparoscopic management of appendicitis and cholelithiasis during pregnancy. Am J Surg 178 (1999) 523-529
28. Peccatori F., Martinelli G., Gentilini O., et al. Chemotherapy during pregnancy: what is really safe?. Lancet Oncol 5 (2004) 398
29. Reynoso E.E., and Huerta F. Acute leukemia and pregnancy-fatal fetal outcome after exposure to idarubicin during the second trimester. Acta Oncol 33 (1994) 709-710
30. Bakri Y.N., and Given Jr. F.T. Normal pregnancy and delivery following conservative surgery and chemotherapy for ovarian endodermal sinus tumor. Gynecol Oncol 19 (1984) 222-225
31. Caluwaerts S., Van Calsteren K., Mertens L., et al. Neoadjuvant chemotherapy followed by radical hysterectomy for invasive cervical cancer diagnosed during pregnancy: report of a case and review of the literature. Int J Gynecol Cancer 16 (2006) 905-908
32. Elit L., Bocking A., Kenyon C., et al. An endodermal sinus tumor diagnosed in pregnancy: case report and review of the literature. Gynecol Oncol 72 (1999) 123-127
33. Ferrandina G., Distefano M., Testa A., et al. Management of an advanced ovarian cancer at 15 weeks of gestation: case report and literature review. Gynecol Oncol 97 (2005) 693-696
34. Garrido M., Clavero J., Huete A., et al. Prolonged survival of a woman with lung cancer diagnosed and treated with chemotherapy during pregnancy. Review of cases reported. Lung Cancer 60 (2008) 285-290
35. Han J.Y., Nava-Ocampo A.A., Kim T.J., et al. Pregnancy outcome after prenatal exposure to bleomycin, etoposide and cisplatin for malignant ovarian germ cell tumors: report of 2 cases. Reprod Toxicol 19 (2005) 557-561
36. Horbelt D., Delmore J., Meisel R., et al. Mixed germ cell malignancy of the ovary concurrent with pregnancy. Obstet Gynecol 84 (1994) 662-664
37. Karimi Z.M., Behtash N., and Modares G.M. Good pregnancy outcome after prenatal exposure to bleomycin, etoposide and cisplatin for ovarian immature teratoma: a case report and literature review. Arch Gynecol Obstet 277 (2008) 75-78
38. Kim D.S., and Park M.I. Maternal and fetal survival following surgery and chemotherapy of endodermal sinus tumor of the ovary during pregnancy: a case report. Obstet Gynecol 73 (1989) 503-507
39. Kim J.H., Kim H.S., Sung C.W., et al. Docetaxel, gemcitabine, and cisplatin administered for non-small cell lung cancer during the first and second trimester of an unrecognized pregnancy. Lung Cancer 59 (2008) 270-273
40. Machado F., Vegas C., Leon J., et al. Ovarian cancer during pregnancy: analysis of 15 cases. Gynecol Oncol 105 (2007) 446-450
41. Malhotra N., and Sood M. Endodermal sinus tumor in pregnancy. Gynecol Oncol 78 (2000) 265-266
42. Otton G., Higgins S., Phillips K.A., et al. A case of early-stage epithelial ovarian cancer in pregnancy. Int J Gynecol Cancer 11 (2001) 413-417
43. Palaia I., Pernice M., Graziano M., et al. Neoadjuvant chemotherapy plus radical surgery in locally advanced cervical cancer during pregnancy: a case report. Am J Obstet Gynecol 197 (2007) e5-e6
44. Raffles A., Williams J., Costeloe K., et al. Transplacental effects of maternal cancer chemotherapy. Case report. Br J Obstet Gynaecol 96 (1989) 1099-1100
45. Robova H., Rob L., Hrehorcak M., et al. Endodermal sinus tumor diagnosed in pregnancy: a case report. Int J Gynecol Cancer 17 (2007) 914-916
46. Sood A.K., Shahin M.S., and Sorosky J.I. Paclitaxel and platinum chemotherapy for ovarian carcinoma during pregnancy. Gynecol Oncol 83 (2001) 599-600
47. Henderson C.E., Elia G., Garfinkel D., et al. Platinum chemotherapy during pregnancy for serous cystadenocarcinoma of the ovary. Gynecol Oncol 49 (1993) 92-94
48. Picone O., Lhomme C., Tournaire M., et al. Preservation of pregnancy in a patient with a stage IIIB ovarian epithelial carcinoma diagnosed at 22 weeks of gestation and treated with initial chemotherapy: case report and literature review. Gynecol Oncol 94 (2004) 600-604
49. Bader A.A., Schlembach D., Tamussino K.F., et al. Anhydramnios associated with administration of trastuzumab and paclitaxel for metastatic breast cancer during pregnancy. Lancet Oncol 8 (2007) 79-81
50. Gadducci A., Cosio S., Fanucchi A., et al. Chemotherapy with epirubicin and paclitaxel for breast cancer during pregnancy: case report and review of the literature. Anticancer Res 23 (2003) 5225-5229
51. Gonzalez-Angulo A.M., Walters R.S., Carpenter Jr. R.J., et al. Paclitaxel chemotherapy in a pregnant patient with bilateral breast cancer. Clin Breast Cancer 5 (2004) 317-319
52. Hubalek M., Smekal-Schindelwig C., Zeimet A.G., et al. Chemotherapeutic treatment of a pregnant patient with ovarian dysgerminoma. Arch Gynecol Obstet 276 (2007) 179-183
53. Lycette J.L., Dul C.L., Munar M., et al. Effect of pregnancy on the pharmacokinetics of paclitaxel: a case report. Clin Breast Cancer 7 (2006) 342-344
54. Mantovani G., Gramignano G., Mais V., et al. Use of chemotherapy for ovarian cancer during human pregnancy: case report and literature review. Eur J Obstet Gynecol Reprod Biol 131 (2007) 238-239
55. Mendez L.E., Mueller A., Salom E., et al. Paclitaxel and carboplatin chemotherapy administered during pregnancy for advanced epithelial ovarian cancer. Obstet Gynecol 102 (2003) 1200-1202
56. Modares G.M., Karimi Z.M., Behtash N., et al. Preservation of pregnancy in a patient with advanced ovarian cancer at 20 weeks of gestation: case report and literature review. Int J Gynecol Cancer 17 (2007) 1140-1143
57. Garcia M.M., Lopez G.G., Pina I.L., et al. [Breast cancer during pregnancy]. Rev Med Univ Navarra 52 (2008) 18-24
58. Garcia-Gonzalez J., Cueva J., Lamas M.J., et al. Paclitaxel and cisplatin in the treatment of metastatic non-small-cell lung cancer during pregnancy. Clin Transl Oncol 10 (2008) 375-376
59. De Santis M., Lucchese A., De Carolis S., et al. Metastatic breast cancer in pregnancy: first case of chemotherapy with docetaxel. Eur J Cancer Care 9 (2000) 235-237
60. Gainford M.C., and Clemons M. Breast cancer in pregnancy: are taxanes safe?. Clin Oncol 18 (2006) 159
61. Nieto Y., Santisteban M., Aramendia J.M., et al. Docetaxel administered during pregnancy for inflammatory breast carcinoma. Clin Breast Cancer 6 (2006) 533-534
62. Potluri V., Lewis D., and Burton G.V. Chemotherapy with taxanes in breast cancer during pregnancy: case report and review of the literature. Clin Breast Cancer 7 (2006) 167-170
63. Sekar R., and Stone P.R. Trastuzumab use for metastatic breast cancer in pregnancy. Obstet Gynecol 110 (2007) 507-510
64. Motegi M., Takakura S., Takano H., et al. Adjuvant chemotherapy in a pregnant woman with endodermal sinus tumor of the ovary. Obstet Gynecol 109 (2007) 537-540
65. Mir O., Berveiller P., Ropert S., et al. Emerging therapeutic options for breast cancer chemotherapy during pregnancy. Ann Oncol 19 (2008) 607-613
66. Pant S., Landon M.B., Blumenfeld M., et al. Treatment of breast cancer with trastuzumab during pregnancy. J Clin Oncol 26 (2008) 1567-1569
67. Watson W.J. Herceptin (trastuzumab) therapy during pregnancy: association with reversible anhydramnios. Obstet Gynecol 105 (2005) 642-643
68. Shrim A., Garcia-Bournissen F., Maxwell C., et al. Favorable pregnancy outcome following Trastuzumab (Herceptin) use during pregnancy-case report and updated literature review. Reprod Toxicol 23 (2007) 611-613
69. Fanale M.A., Uyei A.R., Theriault R.L., et al. Treatment of metastatic breast cancer with trastuzumab and vinorelbine during pregnancy. Clin Breast Cancer 6 (2005) 354-356
70. Waterston A.M., and Graham J. Effect of adjuvant trastuzumab on pregnancy. J Clin Oncol 24 (2006) 321-322
71. Witzel I.D., Muller V., Harps E., et al. Trastuzumab in pregnancy associated with poor fetal outcome. Ann Oncol 19 (2008) 191-192
72. Paskulin G.A., Gazzola Zen P.R., Camargo Pinto L.L., et al. Combined chemotherapy and teratogenicity. Birth Defects Res A Clin Mol Teratol 73 (2005) 634-637
73. Ring A.E., Smith I.E., Jones A., et al. Chemotherapy for breast cancer during pregnancy: an 18-year experience from five London teaching hospitals. J Clin Oncol 23 (2005) 4192-4197
74. Chelghoum Y., Vey N., Raffoux E., et al. Acute leukemia during pregnancy: a report on 37 patients and a review of the literature. Cancer 104 (2005) 110-117
75. Hahn K.M., Johnson P.H., Gordon N., et al. Treatment of pregnant breast cancer patients and outcomes of children exposed to chemotherapy in utero. Cancer 107 (2006) 1219-1226
76. Aviles A., and Neri N. Hematological malignancies and pregnancy: a final report of 84 children who received chemotherapy in utero. Clin Lymphoma 2 (2001) 173-177
77. Zemlickis D., Lishner M., Erlich R., et al. Teratogenicity and carcinogenicity in a twin exposed in utero to cyclophosphamide. Teratog Carcinog Mutagen 13 (1993) 139-143
78. Van Calsteren K., Berteloot P., Hanssens M., et al. In utero exposure to chemotherapy: effect on cardiac and neurologic outcome. J Clin Oncol 24 (2006) e16-e17
79. Aviles A., Neri N., and Nambo M.J. Long-term evaluation of cardiac function in children who received anthracyclines during pregnancy. Ann Oncol 17 (2006) 286-288
80. Siu B.L., Alonzo M.R., Vargo T.A., et al. Transient dilated cardiomyopathy in a newborn exposed to idarubicin and all-trans-retinoic acid (ATRA) early in the second trimester of pregnancy. Int J Gynecol Cancer 12 (2002) 399-402
81. Achtari C., and Hohlfeld P. Cardiotoxic transplacental effect of idarubicin administered during the second trimester of pregnancy. Am J Obstet Gynecol 183 (2000) 511-512
82. Matsuo K., Shimoya K., Ueda S., et al. Idarubicin administered during pregnancy: its effects on the fetus. Gynecol Obstet Invest 58 (2004) 186-188
83. Johnson S. Cognitive and behavioural outcomes following very preterm birth. Semin Fetal Neonatal Med 12 (2007) 363-373
84. Pentheroudakis G., and Pavlidis N. Cancer and pregnancy: poena magna, not anymore. Eur J Cancer 42 (2006) 126-140
85. Jacobs I.A., Chang C.K., and Salti G.I. Coexistence of pregnancy and cancer. Am Surg 70 (2004) 1025-1029
86. Bonnier P., Romain S., Dilhuydy J.M., et al. Influence of pregnancy on the outcome of breast cancer: a case-control study. Societe Francaise de Senologie et de Pathologie Mammaire Study Group. Int J Cancer 72 (1997) 720-727
87. Chang Y.T., Loong C.C., Wang H.C., et al. Breast cancer and pregnancy. Zhonghua Yi Xue Za Zhi (Taipei) 54 (1994) 223-229
88. Ibrahim E.M., Ezzat A.A., Baloush A., et al. Pregnancy-associated breast cancer: a case-control study in a young population with a high-fertility rate. Med Oncol 17 (2000) 293-300
89. Ishida T., Yokoe T., Kasumi F., et al. Clinicopathologic characteristics and prognosis of breast cancer patients associated with pregnancy and lactation: analysis of case-control study in Japan. Jpn J Cancer Res 83 (1992) 1143-1149
90. Lethaby A.E., O'Neill M.A., Mason B.H., et al. Overall survival from breast cancer in women pregnant or lactating at or after diagnosis. Auckland Breast Cancer Study Group. Int J Cancer 67 (1996) 751-755
91. Nugent P., and O'Connell T.X. Breast cancer and pregnancy. Arch Surg 120 (1985) 1221-1224
92. Petrek J.A., Dukoff R., and Rogatko A. Prognosis of pregnancy-associated breast cancer. Cancer 67 (1991) 869-872
93. Zemlickis D., Lishner M., Degendorfer P., et al. Maternal and fetal outcome after breast cancer in pregnancy. Am J Obstet Gynecol 166 (1992) 781-787
94. Zhang J., Liu G., Wu J., et al. Pregnancy-associated breast cancer: a case control and long-term follow-up study in China. J Exp Clin Cancer Res 22 (2003) 23-27
95. Halaska M.J., Pentheroudakis G., Strnad P., et al. Presentation, management and outcome of 32 patients with pregnancy-associated breast cancer: a matched controlled study. Breast J 15 (2009) 461-467
96. Kahlert S., Bauerfeind I., Strauss A., et al. [Breast cancer treatment during pregnancy - experiences in the department of OB/GYN Grosshadern-Munich and review of international data]. Zentralbl Gynakol 126 (2004) 159-166
97. Hunter M.I., Monk B.J., and Tewari K.S. Cervical neoplasia in pregnancy. Part 1: screening and management of preinvasive disease. Am J Obstet Gynecol 199 (2008) 3-9
98. Economos K., Perez V.N., Delke I., et al. Abnormal cervical cytology in pregnancy: a 17-year experience. Obstet Gynecol 81 (1993) 915-918
99. Robova H., Rob L., Pluta M., et al. Squamous intraepithelial lesion-microinvasive carcinoma of the cervix during pregnancy. Eur J Gynaecol Oncol 26 (2005) 611-614
100. Van Calsteren K., Vergote I., and Amant F. Cervical neoplasia during pregnancy: diagnosis, management and prognosis. Best Pract Res Clin Obstet Gynaecol 19 (2005) 611-630
101. Yost N.P., Santoso J.T., McIntire D.D., et al. Postpartum regression rates of antepartum cervical intraepithelial neoplasia II and III lesions. Obstet Gynecol 93 (1999) 359-362
102. Serati M., Uccella S., Laterza R.M., et al. Natural history of cervical intraepithelial neoplasia during pregnancy. Acta Obstet Gynecol Scand 87 (2008) 1296-1300
103. Siristatidis C., Vitoratos N., Michailidis E., et al. The role of the mode of delivery in the alteration of intrapartum pathological cervical cytologic findings during the postpartum period. Eur J Gynaecol Oncol 23 (2002) 358-360
104. Robinson W.R., Webb S., Tirpack J., et al. Management of cervical intraepithelial neoplasia during pregnancy with LOOP excision. Gynecol Oncol 64 (1997) 153-155
105. Takushi M., Moromizato H., Sakumoto K., et al. Management of invasive carcinoma of the uterine cervix associated with pregnancy: outcome of intentional delay in treatment. Gynecol Oncol 87 (2002) 185-189
106. Lee R.B., Neglia W., and Park R.C. Cervical carcinoma in pregnancy. Obstet Gynecol 58 (1981) 584-589
107. Sood A.K., Sorosky J.I., Krogman S., et al. Surgical management of cervical cancer complicating pregnancy: a case-control study. Gynecol Oncol 63 (1996) 294-298
108. Choi H.J., Roh J.W., Seo S.S., et al. Comparison of the accuracy of magnetic resonance imaging and positron emission tomography/computed tomography in the presurgical detection of lymph node metastases in patients with uterine cervical carcinoma: a prospective study. Cancer 106 (2006) 914-922
109. Fischerova D., Cibula D., Stenhova H., et al. Transrectal ultrasound and magnetic resonance imaging in staging of early cervical cancer. Int J Gynecol Cancer 18 (2008) 766-772
110. Prem K.A., Makowski E.L., and McKelvey J.L. Carcinoma of the cervix associated with pregnancy. Am J Obstet Gynecol 95 (1966) 99-108
111. Sood A.K., Sorosky J.I., Mayr N., et al. Radiotherapeutic management of cervical carcinoma that complicates pregnancy. Cancer 80 (1997) 1073-1078
112. Gao J.Z. [Carcinoma of the uterine cervix associated with pregnancy-analysis of 458 cases]. Zhonghua Zhong Liu Za Zhi 7 (1985) 366-369
113. Saunders N., and Landon C.R. Management problems associated with carcinoma of the cervix diagnosed in the second trimester of pregnancy. Gynecol Oncol 30 (1988) 120-122
114. Wyatt R.M., Beddoe A.H., and Dale R.G. The effects of delays in radiotherapy treatment on tumour control. Phys Med Biol 48 (2003) 139-155
115. Coles C.E., Burgess L., and Tan L.T. An audit of delays before and during radical radiotherapy for cervical cancer-effect on tumour cure probability. Clin Oncol (R Coll Radiol) 15 (2003) 47-54
116. Hunter M.I., Tewari K., and Monk B.J. Cervical neoplasia in pregnancy. Part 2: current treatment of invasive disease. Am J Obstet Gynecol 199 (2008) 10-18
117. Ben Arie A., Levy R., Lavie O., et al. Conservative treatment of stage IA2 squamous cell carcinoma of the cervix during pregnancy. Obstet Gynecol 104 (2004) 1129-1131
118. Van Calsteren K., Hanssens M., Moerman P., et al. Successful conservative treatment of endocervical adenocarcinoma stage Ib1 diagnosed early in pregnancy. Acta Obstet Gynecol Scand 87 (2008) 250-253
119. van de Nieuwenhof H.P., van Ham M.A., Lotgering F.K., et al. First case of vaginal radical trachelectomy in a pregnant patient. Int J Gynecol Cancer 18 (2008) 1381-1385
120. Ungar L., Smith J.R., Palfalvi L., et al. Abdominal radical trachelectomy during pregnancy to preserve pregnancy and fertility. Obstet Gynecol 108 (2006) 811-814
121. Monk B.J., and Montz F.J. Invasive cervical cancer complicating intrauterine pregnancy: treatment with radical hysterectomy. Obstet Gynecol 80 (1992) 199-203
122. Safar P., Uhlir M., Janousek M., et al. [Cervical carcinoma during pregnancy]. Ceska Gynekol 65 (2000) 50-52
123. Sivanesaratnam V., Jayalakshmi P., and Loo C. Surgical management of early invasive cancer of the cervix associated with pregnancy. Gynecol Oncol 48 (1993) 68-75
124. van Vliet W., van Loon A.J., ten Hoor K.A., et al. Cervical carcinoma during pregnancy: outcome of planned delay in treatment. Eur J Obstet Gynecol Reprod Biol 79 (1998) 153-157
125. Robova H., Pluta M., Hrehorcak M., et al. High-dose density chemotherapy followed by simple trachelectomy: full-term pregnancy. Int J Gynecol Cancer 18 (2008) 1367-1371
126. Plante M., Lau S., Brydon L., et al. Neoadjuvant chemotherapy followed by vaginal radical trachelectomy in bulky stage IB1 cervical cancer: case report. Gynecol Oncol 101 (2006) 367-370
127. Bader A.A., Petru E., and Winter R. Long-term follow-up after neoadjuvant chemotherapy for high-risk cervical cancer during pregnancy. Gynecol Oncol 105 (2007) 269-272
128. Benhaim Y., Pautier P., Bensaid C., et al. Neoadjuvant chemotherapy for advanced stage cervical cancer in a pregnant patient: report of one case with rapid tumor progression. Eur J Obstet Gynecol Reprod Biol 136 (2008) 267-268
129. Giacalone P.L., Laffargue F., Benos P., et al. Cis-platinum neoadjuvant chemotherapy in a pregnant woman with invasive carcinoma of the uterine cervix. Br J Obstet Gynaecol 103 (1996) 932-934
130. Karam A., Feldman N., and Holschneider C.H. Neoadjuvant cisplatin and radical cesarean hysterectomy for cervical cancer in pregnancy. Nat Clin Pract Oncol 4 (2007) 375-380
131. Marana H.R., de Andrade J.M., Silva Mathes A.C., et al. Chemotherapy in the treatment of locally advanced cervical cancer and pregnancy. Gynecol Oncol 80 (2001) 272-274
132. Tewari K., Cappuccini F., Gambino A., et al. Neoadjuvant chemotherapy in the treatment of locally advanced cervical carcinoma in pregnancy: a report of two cases and review of issues specific to the management of cervical carcinoma in pregnancy including planned delay of therapy. Cancer 82 (1998) 1529-1534
133. Madeleine M.M., Daling J.R., Carter J.J., et al. Cofactors with human papillomavirus in a population-based study of vulvar cancer. J Natl Cancer Inst 89 (1997) 1516-1523
134. Stroup A.M., Harlan L.C., and Trimble E.L. Demographic, clinical, and treatment trends among women diagnosed with vulvar cancer in the United States. Gynecol Oncol 108 (2008) 577-583
135. Maw R.D. Treatment of external genital warts with 5% imiquimod cream during pregnancy: a case report. BJOG 111 (2004) 1475
136. Latimer J. Gynaecological malignancies in pregnancy. Curr Opin Obstet Gynecol 19 (2007) 140-144
137. Keskin N., Iyibozkurt A.C., Topuz S., et al. Invasive squamous carcinoma of the vulva in women aged less than 40 years: report of two cases and a third case diagnosed during pregnancy. Eur J Gynaecol Oncol 29 (2008) 399-401
138. Bakour S.H., Jaleel H., Weaver J.B., et al. Vulvar carcinoma presenting during pregnancy, associated with recurrent bone marrow hypoplasia: a case report and literature review. Gynecol Oncol 87 (2002) 207-209
139. Ogunleye D., Lewin S.N., Huettner P., et al. Recurrent vulvar carcinoma in pregnancy. Gynecol Oncol 95 (2004) 400-401
140. Vaccarello L., Apte S.M., Copeland L.J., et al. Endometrial carcinoma associated with pregnancy: A report of three cases and review of the literature. Gynecol Oncol 74 (1999) 118-122
141. Schammel D.P., Mittal K.R., Kaplan K., et al. Endometrial adenocarcinoma associated with intrauterine pregnancy. A report of five cases and a review of the literature. Int J Gynecol Pathol 17 (1998) 327-335
142. Ayhan A., Gunalp S., Karaer C., et al. Endometrial adenocarcinoma in pregnancy. Gynecol Oncol 75 (1999) 298-299
143. Foersterling D.L., and Blythe J.G. Ovarian carcinoma, endometrial carcinoma, and pregnancy. Gynecol Oncol 72 (1999) 425-426
144. Ichikawa Y., Takano K., Higa S., et al. Endometrial carcinoma coexisting with pregnancy, presumed to derive from adenomyosis: a case report. Int J Gynecol Cancer 11 (2001) 488-490
145. Itoh K., Shiozawa T., Shiohara S., et al. Endometrial carcinoma in septate uterus detected 6 months after full-term delivery: case report and review of the literature. Gynecol Oncol 93 (2004) 242-247
146. Wall J.A., and Lucci Jr. J.A. Adenocarcinoma of the corpus uteri and pelvic tuberculosis complicating pregnancy; report of case with delivery of live infant and successful recovery. Obstet Gynecol 2 (1953) 629-635
147. Bernhard L.M., Klebba P.K., Gray D.L., et al. Predictors of persistence of adnexal masses in pregnancy. Obstet Gynecol 93 (1999) 585-589
148. Giuntoli R.L., Vang R.S., and Bristow R.E. Evaluation and management of adnexal masses during pregnancy. Clin Obstet Gynecol 49 (2006) 492-505
149. Oehler M.K., Wain G.V., and Brand A. Gynaecological malignancies in pregnancy: a review. Aust N Z J Obstet Gynaecol 43 (2003) 414-420
150. Karlan B.Y., Marrs R., and Lagasse L.D. Advanced-stage ovarian carcinoma presenting during infertility evaluation. Am J Obstet Gynecol 171 (1994) 1377-1378
151. Murdoch W.J. Ovarian surface epithelium, ovulation and carcinogenesis. Biol Rev Camb Philos Soc 71 (1996) 529-543
152. Takeuchi T., Suzuki S., Hayashi Z., et al. Primary ovarian tumor undergoing surgical management during pregnancy. J Nippon Med Sch 69 (2002) 39-42
153. Martinez-Onsurbe P., Ruiz V.A., Sanz Anquela J.M., et al. Aspiration cytology of 147 adnexal cysts with histologic correlation. Acta Cytol 45 (2001) 941-947
154. Guariglia L., Conte M., Are P., et al. Ultrasound-guided fine needle aspiration of ovarian cysts during pregnancy. Eur J Obstet Gynecol Reprod Biol 82 (1999) 5-9
155. Milad M.P., and Olson E. Factors that increase the risk of leakage during surgical removal of benign cystic teratomas. Hum Reprod 14 (1999) 2264-2267
156. Whitecar M.P., Turner S., and Higby M.K. Adnexal masses in pregnancy: a review of 130 cases undergoing surgical management. Am J Obstet Gynecol 181 (1999) 19-24
157. Tewari K., Brewer C., Cappuccini F., et al. Advanced-stage small cell carcinoma of the ovary in pregnancy: long-term survival after surgical debulking and multiagent chemotherapy. Gynecol Oncol 66 (1997) 531-534
158. Zhao X.Y., Huang H.F., Lian L.J., et al. Ovarian cancer in pregnancy: a clinicopathologic analysis of 22 cases and review of the literature. Int J Gynecol Cancer 16 (2006) 8-15
159. Ishioka S., Hayashi T., Endo T., et al. Advanced epithelial ovarian carcinoma during pregnancy. Int J Clin Oncol 12 (2007) 375-378
160. Behtash N., Karimi Z.M., Modares G.M., et al. Ovarian carcinoma associated with pregnancy: a clinicopathologic analysis of 23 cases and review of the literature. BMC Pregnancy Childbirth 8 (2008) 3
161. Tabata T., Nishiura K., Tanida K., et al. Carboplatin chemotherapy in a pregnant patient with undifferentiated ovarian carcinoma: case report and review of the literature. Int J Gynecol Cancer 18 (2008) 181-184
162. Malfetano J.H., and Goldkrand J.W. Cis-platinum combination chemotherapy during pregnancy for advanced epithelial ovarian carcinoma. Obstet Gynecol 75 (1990) 545-547
163. Sankaranarayanan R., and Ferlay J. Worldwide burden of gynaecological cancer: the size of the problem. Best Pract Res Clin Obstet Gynaecol 20 (2006) 207-225
164. Van Calsteren K, Heyns L, De Smet F et al. Cancer during pregnancy: an analysis of 215 patients emphasising the obstetrical and neonatal outcome. J Clin Oncol, in press.