Genistein effects on quantitative ultrasound parameters and bone mineral density in osteopenic postmenopausal women

Osteoporosis International

Volumn 20, Issue 11, 2009, Pages 1947-1954

  Atteritano, M ^a   Mazzaferro, S ^a   Frisina, A ^a   Cannata, M L ^a   Bitto, A ^b   D'Anna, R ^a   Squadrito, F ^b   MacRi I ^a   Frisina, N ^a   Buemi, M ^a  

^a UNIVERSITY OF MESSINA   (Italy)

^b UNIVERSITY OF MESSINA   (Italy)

Author keywords

Bone; Densitometry; Genistein; Menopause; Osteopenia; Ultrasound

Indexed keywords

ALKALINE PHOSPHATASE; CREATININE; DEOXYPYRIDINOLINE; GENISTEIN; PLACEBO; PYRIDINOLINE;

ADULT; AGED; ARTICLE; BONE DENSITY; CALCANEUS; CONTROLLED STUDY; CREATININE URINE LEVEL; DRUG BLOOD LEVEL; DRUG EFFECT; DUAL ENERGY X RAY ABSORPTIOMETRY; FEMALE; FEMUR NECK; HUMAN; LUMBAR SPINE; MAJOR CLINICAL STUDY; OSTEOLYSIS; OSTEOPENIA; PHALANX; POSTMENOPAUSE; PRIORITY JOURNAL; RIGIDITY;

ABSORPTIOMETRY, PHOTON; AGED; BONE DENSITY; BONE DENSITY CONSERVATION AGENTS; CALCANEUS; FEMALE; FEMUR NECK; FINGER PHALANGES; GENISTEIN; HUMANS; LUMBAR VERTEBRAE; MIDDLE AGED; OSTEOPOROSIS, POSTMENOPAUSAL;

EID: 76449118908     PISSN: 0937941X     EISSN: 14332965     Source Type: Journal    
DOI: 10.1007/s00198-009-0883-4     Document Type: Article

References (40)

1. F Albright PH Smith AM. Richarson 1941 Postmenopausal osteoporosis JAMA 116 2 465 2474
2. JA Kanis LJ Melton III C Christiansen, et al. 1994 The diagnosis of osteoporosis J Bone Miner Res 9 1137 1141 7976495 1:STN:280: DyaK2M%2FmslSisA%3D%3D
3. RR. Recker 1993 Current therapy for osteoporosis J Clin Endocrinol Metab 76 14 16 10.1210/jc.76.1.14 8421079 1:STN:280:DyaK3s7jt1WmsA%3D%3D (Pubitemid 23027544)
4. M. Scharbo-Dehaan 1996 Hormone replacement therapy Nurs Prat 21 1 13 1:STN:280:DyaK2szotV2quw%3D%3D
5. RM Neer CD Arnaud JR Zanchetta, et al. 2001 Effect of parathyroid hormone (1-34) on fractures and bone mineral density in postmenopausal women with osteoporosis N Engl J Med 344 19 1434 1441 10.1056/NEJM200105103441904 11346808 1:CAS:528:DC%2BD3MXktVSgsbw%3D (Pubitemid 32402100)
6. HG Ahlborg O Johnell MK. Karlsson 2004 Long term effects of oestrogen therapy on bone loss in postmenopausal women: a 23 year prospective study BJOG 111 335 339 10.1111/j.1471-0528.2004.00068.x 15008769 1:CAS:528: DC%2BD2cXjs1Wntrg%3D (Pubitemid 38446109)
7. C Castelo-Branco F Figueras A Sanjuan, et al. 1999 Long term postmenopausal hormone replacement therapy effects on bone mass:differences between surgical and spontaneous patients Eur J Obstet Gynecol Reprod Biol 83 2 207 211 10.1016/S0301-2115(98)00313-3 10391534 1:CAS:528:DyaK1MXitlKiu7c%3D (Pubitemid 29164430)
8. Writing Group for the Women's Health Initiative Investigators 2002 Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results From the Women's Health Initiative randomized controlled trial JAMA 288 3 321 333 10.1001/jama.288.3.321
9. Collaborative group on Hormonal Factors in Breast Cancer Breast Cancer and hormone replacement therapy 1997 Collaborative reanalysis of data from 51 epidemiological studies of 52705 women with breast cancer and 108411 women without breast cancer Lancet 350 1047 1059 10.1016/S0140-6736(97)08233-0 (Pubitemid 27437855)
10. V. Beral 2003 Million Women Study Collaborators. Breast cancer and hormone replacement therapy in the Million Women Study Lancet 362 419 427 10.1016/S0140-6736(03)14596-5 12927427 1:CAS:528:DC%2BD3sXmt1ajsrw%3D
11. HL Adlecreutz W Mazur 1997 Phyto-estrogen and western disease Ann Med 29 95 120
12. T Horiuchi T Onouchi M Takahashi, et al. 2000 Effect of soy protein on bone metabolism in postmenopausal Japanese women Osteoporos Int 11 721 724 10.1007/s001980070072 11095177 1:CAS:528:DC%2BD3cXnsVegtbg%3D (Pubitemid 30786254)
13. GH Sha SQ. Lin 2008 Genistein inhibits proliferation of human endometrial endothelial cell in vitro Chin Med Sci J 23 1 49 53 10.1016/S1001-9294(09) 60010-9 18437911 1:CAS:528:DC%2BD1cXmtFKms74%3D
14. K Yanagihara A Ito T Toge M. Numoto 1993 Antiproliferative effects of isoflavones on human cancer cell lines established from the gastrointestinal tract Cancer Res. 53 23 5815 5821 8242641 1:CAS:528:DyaK2cXpsV2mug%3D%3D
15. SA Bingham C Atkinson J Liggins, et al. 1998 Phyo-oestrogens: where are we now? Br J Nutr. 79 393 406 10.1079/BJN19980068 9682657 1:CAS:528: DyaK1cXjs1WgsLg%3D (Pubitemid 28223042)
16. GG Kuiper JG Lemmen B Carlsson, et al. 1998 Interaction of estrogenic chemicals and phytoestrogens with estrogen receptor β Endocrinology 139 4252 4263 10.1210/en.139.10.4252 9751507 1:CAS:528:DyaK1cXmsVGmsrw%3D
17. KD Setchell E Lydeking-Olsen 2003 Dietary phytoestrogens and their effect on bone: evidence from in vitro and in vivo, human observational and dietary intervention studies Am J Clin Nutr. 78 593S 609S 12936954 1:CAS:528: DC%2BD3sXntFektLc%3D
18. M Messina S Ho DL Alekel 2004 Skeletal benefits of soy isoflavones: a review of the clinical trial and epidemiologic data Curr Opin Clin Nutr Metab Care 7 649 658 10.1097/00075197-200411000-00010 15534433 1:CAS:528: DC%2BD2MXhslWltQ%3D%3D (Pubitemid 40340636)
19. N Morabito A Crisafulli C Vergara, et al. 2002 Effects of genistein and hormone replacement therapy on bone loss in early postmenopausal women: a randomized double-blind placebo-controlled study J Bone Miner Res. 17 1904 1912 10.1359/jbmr.2002.17.10.1904 12369794 1:CAS:528:DC%2BD38XnvFyitbs%3D
20. H Marini L Minutoli F Polito, et al. 2007 Effects of the phytoestrogen genistein on bone metabolism in osteopenic postmenopausal women: a 2-years randomized, double-blind, placebo-controlled study Annals Internal Medicine 146 12 839 847
21. A Crisafulli D Altavilla G Squadrito, et al. 2004 Effects of the phytoestrogen genistein on the circulating soluble receptor activator of nuclear factor kappaB ligand-osteoprotegerin system in early postmenopausal women J Clin Endocrinol Metab. 89 188 192 10.1210/jc.2003-030891 14715848 1:CAS:528:DC%2BD2cXmvFeqtA%3D%3D (Pubitemid 38183880)
22. H Marini L Minutoli F Polito, et al. 2008 OPG and sRANKL serum concentrations in osteopenic, postmenopausal women after 2-year genistein administration J Bone Miner Res 23 715 720 10.1359/jbmr.080201 18433304 1:CAS:528:DC%2BD1cXmtFyrsbg%3D Published online February (Pubitemid 351575025)
23. M Atteritano H Marini F Polito, et al. 2007 Effects of the phytoestrogen genistein on some predictors of cardiovascular risk in osteopenic, postmenopausal women: a 2-years randomized, double-blind, placebo-controlled study J. Clin Endocr Metab 92 8 3068 3075 10.1210/jc.2006-2295 17682090 1:CAS:528:DC%2BD2sXptl2hsbw%3D (Pubitemid 47236372)
24. R D'Anna ML Cannata M Atteritano, et al. 2007 Effects of the phytoestrogen genistein on hot flushes, endometrium, and vaginal epithelium in postmenopausal women: a 1-year randomized, double-blind, placebo-controlled study Menopause 14 4 648 655 10.1097/01.gme.0000248708.60698.98 17251874 (Pubitemid 47051957)
25. D Altavilla A Crisafulli H Marini, et al. 2004 Cardiovascular effects of the phytoestrogen genistein Curr Med Chem Cardiovasc Hematol Agents 2 179 186 10.2174/1568016043477297 15320800 1:CAS:528:DC%2BD2cXisFWnsLc%3D (Pubitemid 38854979)
26. A Crisafulli H Marini A Bitto, et al. 2004 Effects of genistein on hot flushes in early postmenopausal women: a randomized, double-blind EPT- and placebo controlled study Menopause 11 400 404 10.1097/01.GME.0000109314.11228.E5 15243277 (Pubitemid 40372093)
27. CC. Gluer 1999 Monitoring skeletal changes by radiological techniques J Bone Miner Res 14 1952 1962 10.1359/jbmr.1999.14.11.1952 10571696 1:STN:280:DC%2BD3c%2FktVOqtA%3D%3D (Pubitemid 29521791)
28. H Adlercreutz GJ Wang O Lapcik, et al. 1998 Time-resolved fluoroimmunoassay for plasma enterolactone Anal Biochem. 265 208 215 10.1006/abio.1998.2886 9882394 1:CAS:528:DyaK1MXitVygtQ%3D%3D (Pubitemid 29002063)
29. Bauer DC (1999) Clinical Applications of quantitative ultrasound. In: Njch CF, Hams D, FuerstT Glueer CC, Genant HK (eds) Quantitative ultrasound assessment of osteoporosis and bone status. Martin Dunitz, London, UK, pp 254-297
30. CC. Glüer 1997 Quantitative ultrasound techniques for the assessment of osteoporosis: expert agreement on current status. The International Quantitative Ultrasound Consensus Group J Bone Miner Res. 12 8 1280 1288 10.1359/jbmr.1997.12.8.1280 9258759 Review (Pubitemid 27334975)
31. SC Lee BS Coan ML Bouxsein 1997 Tibial ultrasound velocity measured in situ predicts the material properties of tibial cortical bone Bone. 21 1 119 125 10.1016/S8756-3282(97)00076-8 9213018 1:STN:280:DyaK2szls1GrsA%3D%3D (Pubitemid 27341749)
32. J Zhao Y Jiang D Hans, et al. 1999 QCT, DXA and ultrasound measurement in the distal radius Osteoporos. Int. 8 515 (abstract)
33. Y Jiang J Zhao C Rosen, et al. 1999 Perspectives on bone mechanical properties and adaptive response to mechanical challenge J Clin Densitom. 2 4 423 433 10.1016/S1094-6950(06)60408-3 10677796 1:STN:280:DC%2BD3c7ksVamsA%3D%3D
34. CC Glüer D. Hans 1999 How to use ultrasound for risk assessment: a need for defining strategies Osteoporos Int. 9 3 193 195 10.1007/s001980050135 10450405 (Pubitemid 29182367)
35. F Marín J López-Bastida A Díez-Pérez ECOSAP DXA Substudy Group Investigators, et al. 2004 Bone mineral density referral for dual-energy X-ray absorptiometry using quantitative ultrasound as a prescreening tool in postmenopausal women from the general population: a cost-effectiveness analysis Calcif Tissue Int. 74 3 277 283 10.1007/s00223-003-0135-0 14708042 1:CAS:528:DC%2BD2cXjt1Slurk%3D (Pubitemid 38339578)
36. CC. Glüer 1999 Monitoring skeletal changes by radiological techniques J Bone Miner Res. 14 11 1952 1962 10.1359/jbmr.1999.14.11.1952 10571696 (Pubitemid 29521791)
37. S Gonnelli C Cepollaro A Montagnani, et al. 2002 Heel ultrasonography in monitoring alendronate therapy: a four-year longitudinal study Osteoporos Int 13 415 421 10.1007/s001980200048 12086353 1:CAS:528:DC%2BD38XlsF2gtLs%3D (Pubitemid 34625399)
38. BM Ingle ABC Machado CA Pereda, et al. 2005 Monitoring alendronate and estradiol therapy with quantitative ultrasound and bone mineral density J Clin Densitom. 8 3 278 286 10.1385/JCD:8:3:278 16055957 (Pubitemid 41112843)
39. MA Krieg R Barkmann S Gonnelli, et al. 2008 Quantitative ultrasound in the management of osteoporosis: the 2007 ISCD Official Position J Clin Densitometry 11 163 187 10.1016/j.jocd.2007.12.011 (Pubitemid 351602192)
40. Lenora J, Gerdhem P, Obrant KJ et al (2008). Bone turnover markers are correlated with quantitative ultrasound of the calcaneus: 5-year longitudinal data. Osteoporos Int. doi: 10.1007/s00198-008-0769-x