Ethical issues in deep brain stimulation

Deep Brain Stimulation for Parkinson's Disease

Volumn , Issue , 2007, Pages 323-338

  Wolpe, Paul Root ^a   Ford, Paul J ^b   Harhay, Michael ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b LERNER RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 76449085585     PISSN: None     EISSN: None     Source Type: Book    
DOI: None     Document Type: Chapter

References (60)

1. Kopell BH, Greenberg B, Rezai AR. Deep brain stimulation for psychiatric disorders. J Clin Neurophysiol 2004; 21(1):51-67.
2. Cavuoto J. Neural engineering's image problem. IEEE Spectrum 2004; 32-37.
3. Slater L. Who holds the clicker?. Mother Jones November/December 2005. http://www.motherjones.com/ news / feature /2005/11/ who_holds_clicker.html (last accessed May 23, 2006).
4. Harris G. Device won approval though F.D.A. staff objected. New York Times, 17 February 2006.
5. Okun MS, Tagliati M, Pourfar M, et al. Management of referred deep brain stimulation failures, a retrospective analysis from 2 movement disorders centers. Arch Neurol 2005; 62(8):1250-1255.
6. Fins JJ. 2003. From psychosurgery to neuromodulation and palliation: history's lessons for the ethical conduct and regulation of neuropsychiatric research. Neurosurg Clin N Am 2003; 14(2):303-319, ix-x.
7. Apuzzo ML, Liu CY. The genesis of neurosurgery and the evolution of the neurosurgical operative environmentL Part 1-concepts for future development, 2003 and beyond. Neurosurgery 2003; 52(1):20-33.
8. Stone JL. Dr. Gottlieb Burckhardt. The pioneer of psychosurgery. J Hist Neurosci 2001; 10(1):79-92.
9. Mashour GA, Walker EE, Martuza RL. Psychosurgery: past, present, and future. Brain Res Brain Res Rev 2005; 48(3):409-419.
10. El-Hai J. The Lobotomist: A Maverick Medical Genius and His Tragic Quest to Rid the World of Mental Illness. New York: John Wiley & Sons, Inc., 2005.
11. Baumeister A. The tulane electrical brain stimulation program, a historical case study in medical ethics. J Hist Neurosci 2000; 9(3):262-278.
12. Horgan J. The Forgotten Era of the Brain. Scientific American 2005; 66-74.
13. Breit S, Schulz JB, Benabid AL. Deep brain stimulation. Cell Tissue Res 2004; 318(1):275-288.
14. Rodriguez-Oroz MC, Obeso JA, Lang AE, et al. Bilateral deep brain stimulation in Parkinson's disease: a multicentre study with 4 years follow-up. Brain 2005; 128(Pt 10):2240-2249.
15. Erola T, Heikkinen ER, Haapaniemi T, et al. Efficacy of bilateral subthalamic nucleus (STN) stimulation in Parkinson's disease. Acta Neurochir 2006; 148(4):389-394.
16. Miyawaki E, Perlmutter JS, Troster AI, et al. The behavioral complications of pallidal stimulation: a case report. Brain Cogn 2000; 42(3):417-434.
17. Goodman RR, Kim B, McClelland S III, et al. Operative techniques and morbidity with subthalamic nucleus deep brain stimulation in 100 consecutive patients with advanced Parkinson's disease. J Neurol Neurosurg Psychiatry 2006; 77(1):12-17.
18. Anderson VC, Burchiel KJ, Hogarth P, et al. Pallidal vs subthalamic nucleus deep brain stimulation in Parkinson disease. Arch Neurol 2005; 62(4):554-560.
19. Santos P, Valero R, Arguis MJ, et al. Preoperative adverse events during stereotactic microelectrode-guided deep brain surgery in Parkinson's disease. Rev Esp Anestesiol Reanim 2004; 51(9):523-530.
20. Landi A, Parolin M, Piolti R, et al. Deep brain stimulation for the treatment of Parkinson's disease: the experience of the Neurosurgical Department in Monza. Neurol Sci 2003; 24(suppl 1):S43-S44.
21. Terao T, Takahashi H, Yokochi F, et al. Hemorrhagic complication of stereotactic surgery in patients with movement disorders. J Neurosurg 2003; 98(6):1241-1246.
22. Binder DK, Rau G, Starr PA. Hemorrhagic complications of microelectrode-guided deep brain stimulation. Stereotact Funct Neurosurg 2003; 80(1-4):28-31.
23. Constantoyannis C, BerkC, Honey CR, et al. Reducing hardware-related complications of deep brain stimulation. Can J Neurol Sci 2005; 32(2):194-200.
24. Benabid AL, Chabardes S, Seigneuret E. Deep-brain stimulation in Parkinson's disease: long-term efficacy and safety-What happened this year? Curr Op Neurol 2005; 18(6):623-630.
25. Oh MY, Abosch A, Kim SH, et al. Long-term hardware-related complications of deep brain stimulation. Neurosurgery 2002; 50(6):1268-1274.
26. Terao T, Okiyama R, Takahashi H, et al. Comparison and examination of stereotactic surgical complications in movement disorders. No Shinkei Geka 2003; 31(6):629-636.
27. Lyons KE, Pahwa R. Deep brain stimulation and essential tremor. J Clin Neurophysiol 2004; 21(1):2-5.
28. Beric A, Kelly PJ, Rezai A, et al. Complications of deep brain stimulation surgery. Stereotact Funct Neurosurg 2001; 77(1-4):73-78.
29. Terao T, Okiyama R, Takahashi H, et al. Comparison and examination of stereotactic surgical complications in movement disorders. No Shinkei Geka 2003; 31(6):629-636.
30. Salvador-Aguiar C, Menendez-Guisasola L, Blazquez-Estrada M, et al. Psychiatric symptoms of Parkinson's disease following deep brain stimulation surgery on the subthalamic nucleus. Revista de Neurologia 2004; 39(7):651-655.
31. Funkiewiez A, Ardouin C, Caputo E, et al. Long term effects of bilateral subthalamic nucleus stimulation on cognitive function, mood, and behaviour in Parkinson's disease. J Neurol Neurosurg Psychiatry 2004; 75(6):834-839.
32. Temel Y, Kessels A, Tan S, et al. Behavioural changes after bilateral subthalamic stimulation in advanced Parkinson disease: a systematic review. Parkinsonism Relat Disord 2006; In press.
33. Saint-Cyr JA, Trepanier LL, Kumar R, Lozano AM, Lang AE. Neuropsychological consequences of chronic bilateral stimulation of the subthalamic nucleus in Parkinson's disease. Brain 2000; 123(10):2091-2108.
34. Barichella M, Marczewska AM, Mariani C, et al. Body weight gain rate in patients with Parkinson's disease and deep brain stimulation. Mov Disord 2003; 18(11):1337-1340.
35. Seif C, Herzog J, van der Horst C, et al. Effect of subthalamic deep brain stimulation on the function of the urinary bladder. Ann Neurol 2004; 55(1):118-120.
36. Kedia S, Moro E, Tagliati M, et al. Emergence of restless legs syndrome during subthalamic stimulation for Parkinson disease. Neurology 2004; 63(12):2410-2412.
37. Dujardin K, Blairy S, Defebvre L, et al. Subthalamic nucleus stimulation induces deficits in decoding emotional facial expressions in Parkinson's disease. J Neurol Neurosurg Psychiatry 2004; 75(2):202-208.
38. Hummel T, Jahnke U, Sommer U, et al. Olfactory function in patients with idiopathic Parkinson's disease: effects of deep brain stimulation in the subthalamic nucleus. J Neural Transm 2005; 112(5):669-676.
39. Tornqvist AL, Schalen L, Rehncrona S. Effects of different electrical parameter settings on the intelligibility of speech in patients with Parkinson's disease treated with subthalamic deep brain stimulation. Mov Disord 2005; 20(4):416-423.
40. Francel P, Ryder K, Wetmore J, et al. Deep brain stimulation for Parkinson's disease: association between stimulation parameters and cognitive performance. Stereotact Funct Neurosurg 2004; 82(4):191-193.
41. Okun MS, Green J, Saben R, et al. Mood changes with deep brain stimulation of STN and GPi: results of a pilot study. J Neurol Neurosurg Psychiatry 2003; 74(11):1584-1586.
42. Vitek JL. Deep brain stimulation for Parkinson's disease. A critical re-evaluation of STN versus GPi DBS. Stereotact Funct Neurosurg 2002; 78(3-4):119-131.
43. Burkhard PR, Vingerhoets FJ, Berney A, et al. Suicide after successful deep brain stimulation for movement disorders. Neurology 2004; 63(11):2170-2172.
44. Burn DJ, Troster AI. Neuropsychiatric complications of medical and surgical therapies for Parkinson's disease. J Geriatr Psychiatry Neurol 2004; 17(3):172-180.
45. Fields JA, Troster AI. Cognitive outcomes after deep brain stimulation forParkinson's disease: a review of initial studies and recommendations for future research. Brain Cogn 2000; 42(2):268-293.
46. Deuschl G, Bain P. Deep brain stimulation for tremor: patient selection and evaluation. Mov Disord 2002; 17(suppl 3):S102-S111.
47. Lopiano L, Rizzone M, Bergamasco B, et al. Deep brain stimulation of the subthalamic nucleus in PD: an analysis of the exclusion causes. J Neurol Sci 2002; 195(2):167-170.
48. Ford PJ, Kubu CS. Stimulating debate: Ethics in a multidisciplinary functional neurosurgery committee. J Med Ethics 2005; 32(2):106-109.
49. Moreno J, Caplan AL, Wolpe PR. Updating protections for human subjects involved in research. JAMA 1998; 280(22):1951-1958.
50. Scarrow AM, Scarrow MR. Informed consent for the Neurosurgeon. Surg Neurol 2002; 57(1):63-69.
51. Van Horn G, Schiess M, Soukup V. Subthalamic Deep Brain Stimulation, Neurobehavioral Concerns. Arch Neurol 2001; 58(8):1205-1206.
52. Freeman TB, Vawter DE, Gervais KG, et al. The modern era of surgical trial designs: Perspectives of Parkinson's disease (PD) researchers. Exp Neurol 2006; 198(2): 568-569.
53. McKneally MF, Daar AS. Introducing new technologies: protecting subjects of surgical innovation and research. World J Surg 2003; 27(8):930-935.
54. Wolpe PR, Moreno J, Caplan AL. Ethical principles and history. In: Pincus HA, Lieberman JA, Ferris S, eds. Ethics in Psychiatric Research: A Resource Manual for Human Subjects Protection. Washington, D.C.: The American Psychiatric Association, 1999.
55. Frank S, Kieburtz K, Holloway R, et al. What is the risk of sham surgery in Parkinson disease clinical trials? A review of published reports. Neurology 2005; 65(7): 1101-1103.
56. Kim SY, Frank S, Holloway R, et al. Science and ethics of sham surgery: a survey of Parkinson disease clinical researchers. Arch Neurol 2005; 62(9):1357-1360.
57. Dekkers W, Boer G. Sham neurosurgery in patients with Parkinson's disease: is it morally acceptable? J Med Ethics 2001; 27(3):151-156.
58. Weijer C. I need a placebo like I need a hole in the head. J Law Med Ethics 2002; 30(1):69-72.
59. Macklin R. The ethical problems with sham surgery in clinical research. New Engl J Med 1999; 341(13):992-996.
60. Drizis TJ. Ethics in surgery. Eur Surg Res 2004; 36(suppl 1):88-89.