Characterization of promoter elements involved in the down-regulation of topoisomerase IIα expression in a drug-resistant cell line

Gene

Volumn 342, Issue 1, 2004, Pages 145-155

  Saxena, Deepa ^a   Yiu, Gary K ^a   Ni, Xiaoyan ^a   Huang, Kuan Chun ^a   Mantovani, Roberto ^b   Jacquemin Sablon, Alain G ^c   Ng, Shu Wing ^a  

^a Laboratory of Gynecologic Oncology   (United States)

^b Dipto di Genet e di Biol ei M   (Italy)

^c INSTITUT BERGONIÉ   (France)

Author keywords

Drug resistance; Promoter analysis; Topoisomerase; Transcriptional regulation

Indexed keywords

PROTEIN DERIVATIVE; TATA BINDING PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR SP1;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CELL LINE; CHINESE HAMSTER; CONTROLLED STUDY; CORRELATION ANALYSIS; DOWN REGULATION; GEL MOBILITY SHIFT ASSAY; GENE; GENE CONTROL; GENE LOCATION; GENE MUTATION; GENE SEQUENCE; GENETIC ANALYSIS; IMMUNOBLOTTING; MUTATIONAL ANALYSIS; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; TOPOISOMERASE 2ALPHA GENE;

ANIMALS; ANTIGENS, NEOPLASM; BASE SEQUENCE; BINDING SITES; BLOTTING, WESTERN; CELL LINE; CHLORAMPHENICOL O-ACETYLTRANSFERASE; CRICETINAE; CRICETULUS; DNA TOPOISOMERASES, TYPE II, EUKARYOTIC; DNA-BINDING PROTEINS; DOWN-REGULATION; DRUG RESISTANCE; ELECTROPHORETIC MOBILITY SHIFT ASSAY; ELLIPTICINES; GENE EXPRESSION REGULATION; LUCIFERASES; MOLECULAR SEQUENCE DATA; MUTATION; OLIGONUCLEOTIDES; PROMOTER REGIONS (GENETICS); PROTEIN BINDING; RECOMBINANT FUSION PROTEINS; REGULATORY SEQUENCES, NUCLEIC ACID; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TRANSCRIPTION FACTORS; TRANSFECTION; TUMOR SUPPRESSOR PROTEIN P53;

CRICETINAE; CRICETULUS GRISEUS;

EID: 7644221170     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.gene.2004.07.033     Document Type: Article

References (30)

1. H. Asahara, S. Dutta, H.Y. Kao, R.M. Evans, and M. Montminy Pbx-Hox heterodimers recruit coactivator-corepressor complexes in an isoform-specific manner Mol. Cell. Biol. 19 1999 8219 8225
2. S.J. Backer, S. Markowitz, E.R. Fearon, J.K. Wilson, and B. Vogelstein Suppression of human colorectal carcinoma cell growth by wild-type p53 Science 249 1990 912 915
3. W.T. Beck, S.E. Morgan, Y.Y. Mo, and U.G. Bhat Tumor cell resistance to DNA topoisomerase II inhibitors: new developments Drug Resist. Updat. 2 1999 382 389
4. M. Bellorini, D.K. Lee, J.C. Dantonel, K. Zemzoumi, R.G. Roeder, L. Tora, and R. Mantovani CCAAT binding NF-Y-TBP interactions: NF-YB and NF-YC require short domains adjacent to their histone fold motifs for association with TBP basic residues Nucleic Acid Res. 25 1997 2174 2181
5. C. Chitikila, K.L. Huisinga, J.D. Irvin, A.D. Basehoar, and B.F. Pugh Interplay of TBP inhibitors in global transcriptional control Mol. Cell 10 2002 871 882
6. S.L. Davies, R. Popert, M. Coptcoat, I.D. Hickson, and J.R. Masters Response to epirubicin in patients with superficial bladder cancer and expression of the topoisomerase II alpha and beta genes Int. J. Cancer 65 1996 63 66
7. A.M. Dingemans, M.A. Witlox, R.A. Stallaert, P. van der Valk, P.E. Postmus, and G. Giaccone Expression of DNA topoisomerase II alpha and topoisomerase II beta genes predicts survival and response to chemotherapy in patients with small cell lung cancer Clin. Cancer Res. 5 1999 2048 2058
8. J.P. Eder Jr., V.T. Chan, S.W. Ng, N.A. Rizvi, S. Zacharoulis, B.A. Teicher, and L.E. Schipper DNA topoisomerase IIα expression is associated with alkylating agent resistance Cancer Res. 55 1995 6109 6116
9. A.M. Fry, C.M. Chresta, S.M. Davis, M.C. Walker, A.L. Harris, J.A. Hartley, J.R.W. Masters, and I.D. Hickson Relationship between topoisomerase II level and chemosensitivity in human tumor cell lines Cancer Res. 51 1991 6592 6595
10. G. Giaccone, A.F. Gazdar, H. Beck, F. Zunino, and G. Capranico Multidrug sensitivity phenotype of human lung cancer cells associated with topoisomerase II expression Cancer Res. 52 1992 1666 1674
11. R.J. Issac, A.L. Harris, and I.D. Hickson Regulation of the human topoisomerase II gene promoter in confluence-arrested cells J. Biol. Chem. 271 1996 16741 16747
12. J.R. Jenkins, P. Ayton, T. Jones, S.L. Davis, D.L. Simmons, A.L. Harris, D. Sheer, and I.D. Hickson Isolation of cDNA clones encoding the beta isozyme of human DNA topoisomerase II and localization of the gene to chromosome 3p24 Nucleic Acid Res. 20 1992 5587 5592
13. T. Khelifa, M.R. Casabianca-Pignede, B. Rene, and A. Jacquemin-Sablon Expression of topoisomerase IIα and β in Chinese hamster lung cells resistant to topoisomerase inhibitors Mol. Pharmacol. 46 1994 323 328
14. S.J. Kim, J.G. Na, M. Hampsey, and D. Reinberg The Dr1/DRAP1 heterodimer is a global repressor of transcription in vivo Proc. Natl. Acad. Sci. U. S. A. 94 1997 820 825
15. K. Kimura, M. Saijo, M. Ui, and T. Enomoto Growth state- and cell cycle-dependent fluctuation in the expression of two forms of DNA topoisomerase II and possible specific modification of the higher molecular weight form in the M phase J. Biol. Chem. 269 1994 1173 1176
16. T. Kubo, K. Kohno, T. Ohga, K. Taniguchi, K. Kawanami, M. Wada, and M. Kuwano DNA topoisomerase IIalpha gene expression under transcriptional control in etoposide/teniposide-resistant human cancer cells Cancer Res. 17 1995 3860 3864
17. L.F. Liu, T.C. Rowe, L. Yang, K.M. Tewey, and G.L. Chen Cleavage of DNA by mammalian DNA topoisomerase II J. Biol. Chem. 258 1983 15365 15370
18. D. Liu, C.L. Huang, K. Kameyama, E. Hayashi, A. Yamauchi, S. Sumitomo, and H. Yokomise Topoisomerase IIalpha gene expression is regulated by the p53 tumor suppressor gene in nonsmall cell lung carcinoma patients Cancer 94 2002 2239 2247
19. R. Mantovani, U. Pessara, F. Tronche, X.Y. Li, A.M. Knapp, J.L. Pasquali, C. Benoist, and D. Mathis Monoclonal antibodies to NF-Y define its function in MHC class II and albumin gene transcription EMBO J. 11 1992 3315 3322
20. A. Maxam, and W. Gilbert Sequencing end-labeled DNA with base-specific chemical cleavages Methods Enzymol. 65 1980 499 560
21. A. Maxwell, and M. Gellert Mechanistic aspects of DNA topoisomerases Adv. Protein Chem. 38 1986 69 107
22. E.M. Nelson, K.M. Tewey, and L.F. Liu Mechanism of antitumor drug action: poisoning of mammalian DNA topoisomerase II on DNA by 4′-(9- acridinylamino)-methanesulfon-m-anisidide Proc. Natl. Acad. Sci. U. S. A. 81 1984 1361 1365
23. S.W. Ng, J.P. Eder, L.E. Schnipper, and V.T.W. Chan Molecular cloning and characterization of the promoter for the Chinese hamster DNA topoisomerase IIα gene J. Biol. Chem. 270 1995 25850 25858
24. Y. Peng, and N. Jahroudi The NFY transcription factor functions as a repressor and activator of the von Willebrand factor promoter Blood 99 2002 2408 2417
25. Y. Pommier, D. Kerrigan, J.M. Covey, C.S. Kao-Shan, and J. Whang-Peng Sister chromatid exchanges, chromosomal aberrations, and cytotoxicity produced by antitumor topoisomerase II inhibitors in sensitive (DC-3F) and resistant (DC-3F/9-OHE) Chinese hamster cells Cancer Res. 48 1988 512 516
26. H. Takano, T. Ise, M. Nomoto, K. Kato, T. Murakami, H. Ohmori, T. Imamura, G. Nagatani, T. Okamoto, R. Ohta, M. Furukawa, K. Shibao, H. Izumi, M. Kuwano, and K. Kohno Structural and functional analysis of the control region of the human DNA topoisomerase IIα gene in drug-resistant cells Anti-Cancer Drug Des. 14 1999 87 92
27. M. Tsai-Pflugfelder, L.F. Liu, A.A. Liu, K.M. Tewey, J. Whang-Peng, T. Knutsen, K. Huebner, C.M. Croce, and J.C. Wang Cloning and sequencing of cDNA encoding human DNA topoisomerase II and localization of the gene to chromosome region 17q21-22 Proc. Natl. Acad. Sci. U. S. A. 85 1988 7177 7181
28. J.C. Wang Cellular roles of DNA topoisomerases: a molecular perspective Nat. Rev., Mol. Cell Biol. 3 2002 430 440
29. Q. Wang, G.P. Zambetti, and D.P. Suttle Inhibition of DNA topoisomerase II alpha gene expression by the p53 tumor suppressor Mol. Cell. Biol. 17 1997 389 397
30. J.H. Yoon, J.K. Kim, G.B. Rha, M. Oh, S.H. Park, and R.H. Seong Sp1 mediates cell proliferation-dependent regulation of rat DNA topoisomerase IIα gene promoter Biochem. J. 344 1999 367 374