Response to epirubicin in patients with superficial bladder cancer and expression of the topoisomerase II α and β genes

International Journal of Cancer

Volumn 65, Issue 1, 1996, Pages 63-66

  Davies, Sally L ^a   Popert, Rick ^b   Coptcoat, Malcolm ^b   Hickson, Ian D ^a   Masters, John R W ^c  

^a JOHN RADCLIFFE HOSPITAL   (United Kingdom)

^b KING'S COLLEGE LONDON   (United Kingdom)

^c INSTITUTE OF UROLOGY AND NEPHROLOGY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DNA TOPOISOMERASE (ATP HYDROLYSING); EPIRUBICIN;

ADULT; AGED; ARTICLE; BIOPSY; BLADDER CANCER; CLINICAL ARTICLE; FEMALE; GENE EXPRESSION; HUMAN; HUMAN TISSUE; MALE; PRIORITY JOURNAL;

AGED; ANTIBIOTICS, ANTINEOPLASTIC; ANTINEOPLASTIC AGENTS; CARCINOMA, TRANSITIONAL CELL; DNA TOPOISOMERASES, TYPE II; ENZYME INHIBITORS; EPIRUBICIN; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; ISOENZYMES; MALE; MIDDLE AGED; URINARY BLADDER NEOPLASMS;

EID: 0030031170     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0215(19960103)65:1<63::AID-IJC11>3.0.CO;2-J     Document Type: Article

References (22)

1. AUSTIN, C.A., SNG, J.-W., PATEL, S. and FISHER, L.M., Novel HeLa topoisomerase II is the IIβ isoform: complete coding sequence and homology with other type II topoisomerases. Biochim. biophys. Acta, 1172, 283-291 (1993).
2. AUSUBEL, P.M., BRENT, R., KINGSTON, R.E., MOORE, D.D., SEIDMAN, J.G., SMITH, J.A. and STRUHL, K., Current protocols in molecular biology, Greene and Wiley Interscience Press. New York (1989).
3. BECK, W.T. and DANKS, M.K., Mechanisms of resistance to drugs that inhibit DNA topoisomerases. Semin. Cancer Biol., 2, 235-244 (1991).
4. CHOMCZYNSKI, P. and SACCHI, N., Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem., 162, 156-159 (1987).
5. CHUNG, T.D.Y., DRAKF, F.H., TAN, K.B., PER, S.R., CROOKE, S.T. and MIRABELLI, C.K., Characterization and immunological identification of cDNA clones encoding two human DNA topoisomerase II isozymes. Proc. nat. Acad. Sci. (Wash.), 86, 9431-9435 (1989).
6. DAVIES, S.L., JENKINS, J.R. and HICKSON, I.D., Human cells express two differentially spliced forms of topoisomerase II β mRNA. Nucl. Acids Res., 21, 3719-3723 (1993).
7. DAVIES, S.M., ROBSON, C.N., DAVIES, S.L. and HICKSON, I.D., Nuclear topoisomerase II levels correlate with the sensitivity of mammalian cells to intercalating agents and epipodophyllotoxins. J. biol. Chem., 263, 17724-17729 (1988).
8. DRAKE, F.H., HOHFMANN, G.A., BARTUS, H.F., MATTERN, M.R., CROOKE, S.T. and MIRABELLI, C.K., Biochemical and pharmacological properties of p170 and p180 forms of topoisomerase II. Biochemistry, 28, 8154-8160 (1989).
9. FLEISCHMANN, J. and GOLDBERG, G., Management of superficial transitional cell carcinoma of the bladder. Semin. Urol., 11, 193-204 (1993).
10. FRY, A.M., CHRESTA, C.M., DAVIES, S.M., WALKER, M.C., HARRIS, A.L., HARTLEY, J.A., MASTERS, J.R.W. and HICKSON, I.D., Relationship between topoisomerase II level and chemosensitivity in human tumour cell lines. Cancer Res., 51, 6592-6595 (1991).
11. HASEGAWA, T., ISOBE, K.-I., NAKASHIMA, I. and SHIMOKATA, K., Higher expression of topoisomerase II in lung cancers than normal lung tissues: different expression pattern from topoisomerase I. Biochem. biophys. Res. Comm., 195, 409-414 (1993).
12. JENKINS, J.R., AYTON, P., JONES, T., DAVIES, S.L., SIMMONS, D.L., HARRIS, A.L., SHEER, D. and HICKSON, I.D., Isolation of cDNA clones encoding the β isozyme of human topoisomerase II and localisation of the gene to chromosome 3p24. Nucl. Acids Res., 20, 5587-5592 (1992).
13. KAUFMANN, S.H., KARP, J.E., JONES, R.J., MILLER, C.B., SCHNEIDER, E., ZWELLING, L.A., COWAN, K., WENDEL, K. and BURKE, P.J., Topoisomerase II levels and drug sensitivity in adult acute myelogenous leukemia. Blood, 83, 517-530 (1994).
14. LONG, B.H., WANG, L., LORICO, A., WANG, R.C.C., BRATTAIN, M.G. and CASSAZZA, A.M., Mechanisms of resistance to etoposide and teniposide in acquired resistant human colon and lung carcinoma cell lines. Cancer Res., 51, 5275-5280 (1991).
15. NITISS, J.L., LIU, Y.-X. and HSIUNG, Y., A temperature sensitive topoisomerase II allele confers temperature dependent drug resistance on amsacrine and etoposide: a genetic system for determining the targets of topoisomerase II inhibitors. Cancer Res., 53, 89-93 (1993).
16. POMMIER, Y., DNA topoisomerase I and II in cancer chemotherapy: update and perspectives. Cancer Chemother. Pharmacol., 32, 103-108 (1993).
17. POPERT, R.J.M., GOODALL, J., COPTCOAT, M.J., THOMPSON, P.M., PARMAR, M.K.B. and MASTERS, J.R.W., Superficial bladder cancer: the response of a marker tumour to a single intravesical instillation of epirubicin. Brit. J. Urol., 74, 195-199 (1994).
18. SIMON, S.M. and SCHINDLER, M., Cell biological mechanisms of multidrug resistance in tumors. Proc. nat. Acad. Sci. (Wash.), 91, 3497-3504 (1994).
19. TAN, K.B., DORMAN, T.E., FALLS, K.M., CHUNG, T.D.Y., MIRABELLI, C.K., CROOKE, S.T. and MAO, J., Topoisomerase IIα and topoisomerase IIβ genes: characterization and mapping to human chromosomes 17 and 3, respective. Cancer Res., 52, 231-234 (1992).
20. TSAO, Y.-P., Russo, A., NYAMUSWA, G., SILBER, R. and LIU, L.L., Interaction between replication forks and topoisomerase I-DNA cleavable complexes: studies in a cell-free SV40 DNA replication system. Cancer Res., 53, 5908-5914 (1993).
21. WEBB, C.D., LATHAM, M.D., LOCK, R.B. and SULLIVAN, D.M., Attenuated topoisomerase II content directly correlates with a low level of drug resistances in a Chinese hamster ovary cell line. Cancer Res., 51, 6543-6549 (1991).
22. ZHANG, H., D'ARPA, P. and LIU, L.F., A model for tumor cell killing by topoisomerase poisons. Cancer Cells, 2, 23-27 (1990).