Novel synthesis of optically pure indolylglycinols using lipase-mediated resolution

Synthesis

Volumn , Issue 15, 2004, Pages 2463-2470

  Kouko, Takashi ^a   Kobayashi, Jun Ichi ^a   Ohta, Asami ^a   Sakamoto, Masanori ^a   Kawasaki, Tomomi ^a  

^a MEIJI PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

Amino alcohols; Enzymes; Hydrolysis; Indoles; Kinetic resolution

Indexed keywords

ENZYMES; SYNTHESIS (CHEMICAL);

INDOLYLGLYCINOLS; LIPASE-MEDIATED RESOLUTION;

ALCOHOLS;

2 AMINO 2 (INDOL 3 YL)ETHANOL; 2 AZIDO 2 (INDOL 3 YL)ETHYL ACETATE; ACETIC ACID ETHYL ESTER; AMINOALCOHOL; AZIDE; GLYCINE DERIVATIVE; INDOLE DERIVATIVE; INDOLIN 3 ONE; INDOLYLGLYCINOL; TRIACYLGLYCEROL LIPASE; UNCLASSIFIED DRUG;

ARTICLE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROLYSIS; INFRARED SPECTROSCOPY; MELTING POINT; OPTICAL ROTATION; PROTON NUCLEAR MAGNETIC RESONANCE; REDUCTION; SYNTHESIS; WITTIG REACTION;

EID: 7644221002     PISSN: 00397881     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2004-831217     Document Type: Article

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