Synthesis and biological evaluation of monoindolyl and indolocarbazolyl oxazolones and imidazolones

Chemical and Pharmaceutical Bulletin

Volumn 45, Issue 4, 1997, Pages 733-736

  Pereira, Elisabète Rodrigues ^a   Prudhomme, Michelle ^a   Sancelme, Martine ^a   Ollier, Monique ^b   Severe, Danièle ^c   Riou, Jean François ^c   Crevel, Henri ^d   Savineau, Jean Pierre ^d   Fabbro, Doriano ^e   Meyer, Thomas ^e  

^a UNIVERSITÉ CLERMONT AUVERGNE   (France)

^b INSERM   (France)

^c SANOFI   (France)

^d UNIVERSITÉ DE BORDEAUX   (France)

^e CIBA GEIGY LTD   (Switzerland)

Author keywords

antiproliferation; imidazol 2 one; oxazol 2 one; protein kinase C

Indexed keywords

4 PROPYL 5 (4 PYRIDYL) 2(3H) OXAZOLONE; CALPHOSTIN C; CYCLIC AMP DEPENDENT PROTEIN KINASE; IMIDAZOLE DERIVATIVE; OXAZOLONE; PROTEIN KINASE C; PROTEIN KINASE C INHIBITOR; STAUROSPORINE;

ANIMAL CELL; ANIMAL TISSUE; ANTIBACTERIAL ACTIVITY; ARTICLE; BACILLUS CEREUS; CANCER INHIBITION; DRUG SYNTHESIS; ENZYME INHIBITION; LEUKEMIA P 388; MELANOMA B16; MOUSE; NONHUMAN; RAT; TRACHEA MUSCLE; VASODILATATION;

EID: 0030912365     PISSN: 00092363     EISSN: None     Source Type: Journal    
DOI: 10.1248/cpb.45.733     Document Type: Article

References (20)

1. Nishizuka Y., Science, 33, 305-312 (1986).
2. Buchner K., Eur. J. Biochem. (Tokyo), 228, 211-221 (1995).
3. Herbert J. M., Biochem. Pharmacol., 45, 527-537 (1993).
4. Dumont J. A., Jones W. D., Bitonti A. J., Cancer Res., 52, 1195-1200 (1992).
5. Shimamoto Y., Shimamoto H., Kwan C. Y., Daniel E. E., Am. J. Phvsiol., 264, H1300-H1306 (1993).
6. Rodrigues Pereira E., Spessel V., Prudhomme M., Martre A. M., Mousset G., Tetrahedron Lett., 36, 2479-2482 (1995).
7. Rodrigues Pereira E., Sancelme M., Towa J. J., Prudhomme M., Martre A. M., Mousset G., Rapp M., J. Antibiot., 49, 380-385 (1996).
8. Rodrigues Pereira E., Prudhomme M., Tetrahedron Lett., 36, 2477-2478 (1995).
9. Savineau J. P., Marthan R., Crevel H., Br. J. Pharmacol., 104, 639-644 (1991).
10. Rossetti M., Savineau J. P., Crevel H., Marthan R., Am. J. Physiol., 268, L966-L971 (1995).
11. Lee M. K., Severson D. L., Am. J. Physiol., 267, C659-C678 (1994).
12. Cheng H. C., Robinson P. J., Dage R. C., Jones W. D., J. Cardiovasc. Pharmacol., 17, 445-455 (1991).
13. Schramm C. M., Grunstein M. M., Am. J. Physiol., 262, L119-L139 (1992).
14. Silva A. M., Brum R. L., Calixto J. B., Life Sci., 57, 863-871 (1995).
15. Marte B. M., Meyer T., Stabel S., Gesche J. R., Jaken S., Fabbro D., Hynes N. E., Cell Growth & Diff., 5, 239-247 (1994).
16. McGlynn E., Liebetanz J., Reutener S., Wood J., Lydon N. B., Hofstetter H., Vanek M., Meyer T., Fabbro D., J. Cell. Biochem., 49, 239-250 (1992).
17. Riou J. F., Naudin A., Lavalle F., Biochem. Biophys. Res. Commun., 187, 164-170 (1992).
18. Rodrigues Pereira E., Belin L., Sancelme M., Prudhomme M., Oilier M., Rapp M., Sevère D., Riou J. F., Fabbro D., Meyer T., J. Med. Chem., 39, 4471-4477 (1996).
19. Ben Jebria A., Marthan R., Rossetti M, Savineau J. P., Ultman J. S., Respir. Physiol., 93, 111-123 (1993).
20. Ozaki H., Kwon S. C., Tajimi M., Karaki H., Pflügers Archiv., 416, 351-359 (1990).