The biochemical properties of the mitochondrial thiamine pyrophosphate carrier from Drosophila melanogaster

FEBS Journal

Volumn 277, Issue 5, 2010, Pages 1172-1181

  Iacopetta, Domenico ^a   Carrisi, Chiara ^b   De Filippis, Giuseppina ^b   Calcagnile, Valeria M ^c   Cappello, Anna R ^a   Chimento, Adele ^a   Curcio, Rosita ^a   Santoro, Antonella ^a   Vozza, Angelo ^c   Dolce, Vincenza ^a   Palmieri, Ferdinando ^c   Capobianco, Loredana ^b  

^a UNIVERSITY OF CALABRIA   (Italy)

^b UNIVERSITY OF SALENTO   (Italy)

^c UNIVERSITY OF BARI   (Italy)

Author keywords

CG2857; CG6608; Drosophila melanogaster; Mitochondria; Proteomics; Thiamine pyrophosphate carrier

Indexed keywords

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; CARBON; CARRIER PROTEIN; COCARBOXYLASE; LIPOSOME; NUCLEOTIDE;

ARTICLE; BACTERIUM; BIOCHEMISTRY; CARBON SOURCE; DROSOPHILA MELANOGASTER; GENE; GENE EXPRESSION; GENE IDENTIFICATION; GENE OVEREXPRESSION; GENOME; HUMAN; KINETICS; MITOCHONDRIAL MEMBRANE; MITOCHONDRION; MUTANT; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN TRANSPORT; SACCHAROMYCES CEREVISIAE; YEAST;

AMINO ACID SEQUENCE; ANIMALS; BIOLOGICAL TRANSPORT; CARRIER PROTEINS; DROSOPHILA MELANOGASTER; HUMANS; KINETICS; MITOCHONDRIA; MOLECULAR SEQUENCE DATA; MUTATION; RECOMBINANT PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SEQUENCE ALIGNMENT; THIAMINE PYROPHOSPHATE;

DROSOPHILA MELANOGASTER; SACCHAROMYCES;

EID: 76349126157     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2009.07550.x     Document Type: Article

References (38)

1. Deus B Blum H (1970) Subcellular distribution of thiamine pyrophosphokinase activity in rat liver and erythrocytes. Biochim Biophys Acta 219, 489 492.
2. Hohmann S Meacock PA (1998) Thiamin metabolism and thiamin diphosphate-dependent enzymes in the yeast Saccharomyces cerevisiae: genetic regulation. Biochim Biophys Acta 1385, 201 219.
3. Katsube T, Nomoto S, Togashi S, Ueda R, Kobayashi M Takahisa M (1997) cDNA sequence and expression of a gene encoding a pyruvate dehydrogenase kinase homolog of Drosophila melanogaster. DNA Cell Biol 16, 335 339.
4. Barile M, Passarella S Quagliariello E (1986) Uptake of thiamin by isolated rat liver mitochondria. Biochem Biophys Res Commun 141, 466 473.
5. Barile M, Passarella S Quagliariello E (1990) Thiamine pyrophosphate uptake into isolated rat liver mitochondria. Arch Biochem Biophys 280, 352 357.
6. Barile M, Valenti D, Brizio C, Quagliariello E Passarella S (1998) Rat liver mitochondria can hydrolyse thiamine pyrophosphate to thiamine monophosphate which can cross the mitochondrial membrane in a carrier-mediated process. FEBS Lett 435, 6 10.
7. Marobbio CM, Vozza A, Harding M, Bisaccia F, Palmieri F Walker JE (2002) Identification and reconstitution of the yeast mitochondrial transporter for thiamine pyrophosphate. EMBO J 21, 5653 5661.
8. Lindhurst MJ, Fiermonte G, Song S, Struys E, De Leonardis F, Schwartzberg PL, Chen A, Castegna A, Verhoeven N, Mathews CK et al. (2006) Knockout of Slc25a19 causes mitochondrial thiamine pyrophosphate depletion, embryonic lethality, CNS malformations, and anemia. Proc Natl Acad Sci USA 103, 15927 15932.
9. Dolce V, Fiermonte G, Runswick MJ, Palmieri F Walker JE (2001) The human mitochondrial deoxynucleotide carrier and its role in the toxicity of nucleoside antivirals. Proc Natl Acad Sci USA 98, 2284 2288.
10. Palmieri F (2004) The mitochondrial transporter family (SLC25): physiological and pathological implications. Pflugers Arch 447, 689 709.
11. Palmieri F (2008) Diseases caused by defects of mitochondrial carriers: a review. Biochim Biophys Acta 1777, 564 578.
12. Palmieri F Pierri CL (2009) Structure and function of mitochondrial carriers - Role of the transmembrane helix P and G residues in the gating and transport mechanism. FEBS Lett, doi :.
13. Carrisi C, Madeo M, Morciano P, Dolce V, Cenci G, Cappello AR, Mazzeo G, Iacopetta D Capobianco L (2008) Identification of the Drosophila melanogaster mitochondrial citrate carrier: bacterial expression, reconstitution, functional characterization and developmental distribution. J Biochem 144, 389 392.
14. Zhang YQ, Roote J, Brogna S, Davis AW, Barbash DA, Nash D Ashburner M (1999) stress sensitive B encodes an adenine nucleotide translocase in Drosophila melanogaster. Genetics 153, 891 903.
15. Rikhy R, Ramaswami M Krishnan KS (2003) A temperature-sensitive allele of Drosophila sesB reveals acute functions for the mitochondrial adenine nucleotide translocase in synaptic transmission and dynamin regulation. Genetics 165, 1243 1253.
16. Brand MD, Pakay JL, Ocloo A, Kokoszka J, Wallace DC, Brookes PS Cornwall EJ (2005) The basal proton conductance of mitochondria depends on adenine nucleotide translocase content. Biochem J 392, 353 362.
17. Hartenstein K, Sinha P, Mishra A, Schenkel H, Torok I Mechler BM (1997) The congested-like tracheae gene of Drosophila melanogaster encodes a member of the mitochondrial carrier family required for gas-filling of the tracheal system and expansion of the wings after eclosion. Genetics 147, 1755 1768.
18. Oey NA, Ijlst L, van Roermund CW, Wijburg FA Wanders RJ (2005) dif-1 and colt, both implicated in early embryonic development, encode carnitine acylcarnitine translocase. Mol Genet Metab 85, 121 124.
19. Metzendorf C, Wu W Lind MI (2009) Overexpression of Drosophila mitoferrin in l(2)mbn cells results in dysregulation of Fer1HCH expression. Biochem J 421, 463 471.
20. Payton SG, Haska CL, Flatley RM, Ge Y Matherly LH (2007) Effects of 5′ untranslated region diversity on the posttranscriptional regulation of the human reduced folate carrier. Biochim Biophys Acta 1769, 131 138.
21. Fiore C, Trezeguet V, Le Saux A, Roux P, Schwimmer C, Dianoux AC, Noel F, Lauquin GJ, Brandolin G Vignais PV (1998) The mitochondrial ADP/ATP carrier: structural, physiological and pathological aspects. Biochimie 80, 137 150.
22. Klingenberg M (1989) Molecular aspects of the adenine nucleotide carrier from mitochondria. Arch Biochem Biophys 270, 1 14.
23. Palmieri F, Indiveri C, Bisaccia F Iacobazzi V (1995) Mitochondrial metabolite carrier proteins: purification, reconstitution, and transport studies. Methods Enzymol 260, 349 369.
24. Palmieri F, Agrimi G, Blanco E, Castegna A, Di Noia MA, Iacobazzi V, Lasorsa FM, Marobbio CM, Palmieri L, Scarcia P et al. (2006) Identification of mitochondrial carriers in Saccharomyces cerevisiae by transport assay of reconstituted recombinant proteins. Biochim Biophys Acta 1757, 1249 1262.
25. Palmieri F, Rieder B, Ventrella A, Blanco E, Do PT, Nunes-Nesi A, Trauth AU, Fiermonte G, Tjaden J, Agrimi G et al. (2009) Molecular identification and functional characterization of Arabidopsis thaliana mitochondrial and chloroplastic NAD+ carrier proteins. J Biol Chem 284, 31249 31259.
26. Tripoli G, D'Elia D, Barsanti P Caggese C (2005) Comparison of the oxidative phosphorylation (OXPHOS) nuclear genes in the genomes of Drosophila melanogaster, Drosophila pseudoobscura and Anopheles gambiae. Genome Biol 6, R11.
27. Porcelli D, Barsanti P, Pesole G Caggese C (2007) The nuclear OXPHOS genes in insecta: a common evolutionary origin, a common cis-regulatory motif, a common destiny for gene duplicates. BMC Evol Biol 7, 215.
28. Parisi M, Nuttall R, Edwards P, Minor J, Naiman D, Lu J, Doctolero M, Vainer M, Chan C, Malley J et al. (2004) A survey of ovary-, testis-, and soma-biased gene expression in Drosophila melanogaster adults. Genome Biol 5, R40.
29. Zarrilli R, Oates EL, McBride OW, Lerman MI, Chan JY, Santisteban P, Ursini MV, Notkins AL Kohn LD (1989) Sequence and chromosomal assignment of a novel cDNA identified by immunoscreening of a thyroid expression library: similarity to a family of mitochondrial solute carrier proteins. Mol Endocrinol 3, 1498 1505.
30. Prohl C, Pelzer W, Diekert K, Kmita H, Bedekovics T, Kispal G Lill R (2001) The yeast mitochondrial carrier Leu5p and its human homologue Graves' disease protein are required for accumulation of coenzyme A in the matrix. Mol Cell Biol 21, 1089 1097.
31. Fiermonte G, Paradies E, Todisco S, Marobbio CM Palmieri F (2009) A novel member of solute carrier family 25 (SLC25A42) is a transporter of coenzyme A and adenosine 3′,5′-diphosphate in human mitochondria. J Biol Chem 284, 18152 18159.
32. Letko G, Kuster U, Duszynski J Kunz W (1980) Investigation of the dependence of the intramitochondrial [ATP]/[ADP] ratio on the respiration rate. Biochim Biophys Acta 593, 196 203.
33. Rubin GM Lewis EB (2000) A brief history of Drosophila's contributions to genome research. Science 287, 2216 2218.
34. Fiermonte G, Palmieri L, Dolce V, Lasorsa FM, Palmieri F, Runswick MJ Walker JE (1998) The sequence, bacterial expression, and functional reconstitution of the rat mitochondrial dicarboxylate transporter cloned via distant homologs in yeast and Caenorhabditis elegans. J Biol Chem 273, 24754 24759.
35. Fiermonte G, Walker JE Palmieri F (1993) Abundant bacterial expression and reconstitution of an intrinsic membrane-transport protein from bovine mitochondria. Biochem J 294 (Pt 1 293 299.
36. Sherman F (1991) Getting started with yeast. Methods Enzymol 194, 3 21.
37. Dolce V, Scarcia P, Iacopetta D Palmieri F (2005) A fourth ADP/ATP carrier isoform in man: identification, bacterial expression, functional characterization and tissue distribution. FEBS Lett 579, 633 637.
38. Huson DH, Richter DC, Rausch C, Dezulian T, Franz M Rupp R (2007) Dendroscope: an interactive viewer for large phylogenetic trees. BMC Bioinformatics 8, 460.