Regulatory T cells and immune tolerance to coagulation factor IX in the context of intramuscular AAV1 gene transfer

Molecular Therapy

Volumn 18, Issue 2, 2010, Pages 361-369

  Kelly, Meagan ^a   Bharadwaj, Arpita S ^a   Tacke, Frank ^b   Chao, Hengjun ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY HOSPITAL RWTH AACHEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD CLOTTING FACTOR 9; INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR ALPHA; PARVOVIRUS VECTOR; TRANSCRIPTION FACTOR FOXP3;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIGEN EXPRESSION; ANTIGEN SPECIFICITY; ARTICLE; CD4+ CD25+ T LYMPHOCYTE; CELL FUNCTION; CELL STRUCTURE; CONTROLLED STUDY; DRUG DOSE ESCALATION; DRUG DOSE INCREASE; IMMUNE RESPONSE; IMMUNOLOGICAL TOLERANCE; IN VITRO STUDY; IN VIVO STUDY; LYMPHOCYTE PROLIFERATION; MOUSE; NONHUMAN; REGULATORY T LYMPHOCYTE; SPLEEN CELL; T CELL DEPLETION; UPREGULATION; VIRAL GENE DELIVERY SYSTEM;

ANIMALS; CELL PROLIFERATION; CELLS, CULTURED; DEPENDOVIRUS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FACTOR IX; FLOW CYTOMETRY; GENETIC VECTORS; HUMANS; IMMUNE TOLERANCE; MICE; T-LYMPHOCYTES, REGULATORY;

MUS;

EID: 76349120825     PISSN: 15250016     EISSN: 15250024     Source Type: Journal    
DOI: 10.1038/mt.2009.269     Document Type: Article

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