Construction and validation of a yeast model system for studying in vivo the susceptibility to nucleoside analogues of DNA polymerase gamma allelic variants

Mitochondrion

Volumn 10, Issue 2, 2010, Pages 183-187

  Baruffini, Enrico ^a   Lodi, Tiziana ^a  

^a UNIVERSITY OF PARMA   (Italy)

Author keywords

DNA polymerase gamma; MIP1; NRTIs stavudine toxicity; Pharmacogenetics; POLG mutations SNPs; Yeast model system

Indexed keywords

DNA DIRECTED DNA POLYMERASE GAMMA; MACROPHAGE INFLAMMATORY PROTEIN 1; STAVUDINE;

ALLELE; ARTICLE; CONTROLLED STUDY; GENE CONSTRUCT; GENE EXPRESSION; GENE MUTATION; GENETIC ASSOCIATION; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; IN VIVO STUDY; MITOCHONDRIAL TOXICITY; NONHUMAN; PHARMACOGENETICS; PRIORITY JOURNAL; RECESSIVE GENE; SACCHAROMYCES CEREVISIAE; SINGLE NUCLEOTIDE POLYMORPHISM; VALIDATION PROCESS;

ANTI-RETROVIRAL AGENTS; DNA POLYMERASE I; DNA-DIRECTED DNA POLYMERASE; NUCLEOSIDES; PHARMACOGENETICS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; STAVUDINE;

EID: 76349120598     PISSN: 15677249     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mito.2009.10.002     Document Type: Article

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