Functional characterization and virulence study of ADE8 and GUA1 genes involved in the de novo purine biosynthesis in Candida albicans

FEMS Yeast Research

Volumn 10, Issue 2, 2010, Pages 199-208

  Jiang, Linghuo ^a,b   Zhao, Jingwen ^b   Guo, Rui ^b   Li, Jing ^b   Yu, Liquan ^a   Xu, Deming ^b  

^a TIANJIN MEDICAL UNIVERSITY   (China)

^b TIANJIN UNIVERSITY   (China)

Author keywords

ADE8; C1 folate pool; Candida albicans; GUA1; Purine biosynthesis; Systemic candidiasis

Indexed keywords

ADENINE; AZAURACIL; FOLIC ACID; GUANINE; GUANOSINE MONOPHOSPHATE SYNTHASE; GUANOSINE PHOSPHATE; INOSINATE DEHYDROGENASE; METHOTREXATE; PHOSPHORIBOSYLGLYCINAMIDE FORMYL TRANSFERASE; TETRAHYDROFOLIC ACID; UNCLASSIFIED DRUG;

ARTICLE; CANDIDA ALBICANS; DRUG SENSITIVITY; ESSENTIAL GENE; FUNGAL GENE; FUNGAL STRAIN; FUNGAL VIRULENCE; GENE FUNCTION; HETEROZYGOSITY; HOMOZYGOSITY; HOST; INVASIVE CANDIDIASIS; NONHUMAN; NUTRITION; PURINE SYNTHESIS;

ANIMALS; ANTIFUNGAL AGENTS; CANDIDA ALBICANS; CANDIDIASIS; CARBON-NITROGEN LIGASES; FUNGAL PROTEINS; GENE EXPRESSION REGULATION, FUNGAL; HUMANS; MALE; METHOTREXATE; MICE; MICE, INBRED BALB C; MICROBIAL SENSITIVITY TESTS; PHOSPHORIBOSYLGLYCINAMIDE FORMYLTRANSFERASE; PURINES; URACIL; VIRULENCE;

CANDIDA ALBICANS; MURINAE;

EID: 76349111795     PISSN: 15671356     EISSN: 15671364     Source Type: Journal    
DOI: 10.1111/j.1567-1364.2009.00600.x     Document Type: Article

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