-
1
-
-
34247855853
-
Adipose tissue distribution and risk of metabolic disease: does thiazolidinedione-induced adipose tissue redistribution provide a clue to the answer?
-
Yang X., and Smith U. Adipose tissue distribution and risk of metabolic disease: does thiazolidinedione-induced adipose tissue redistribution provide a clue to the answer?. Diabetologia 50 (2007) 1127-1139
-
(2007)
Diabetologia
, vol.50
, pp. 1127-1139
-
-
Yang, X.1
Smith, U.2
-
3
-
-
0348230958
-
Obesity is associated with macrophage accumulation in adipose tissue
-
Weisberg S.P., McCann D., Desai M., Rosenbaum M., Leibel R.L., and Ferrante Jr. A.W. Obesity is associated with macrophage accumulation in adipose tissue. J. Clin. Invest. 112 (2003) 1796-1808
-
(2003)
J. Clin. Invest.
, vol.112
, pp. 1796-1808
-
-
Weisberg, S.P.1
McCann, D.2
Desai, M.3
Rosenbaum, M.4
Leibel, R.L.5
Ferrante Jr., A.W.6
-
4
-
-
50949108719
-
Dead adipocytes, detected as crown-like structures, are prevalent in visceral fat depots of genetically obese mice
-
Murano I., Barbatelli G., Parisani V., Latini C., Muzzonigro G., Castellucci M., and Cinti S. Dead adipocytes, detected as crown-like structures, are prevalent in visceral fat depots of genetically obese mice. J. Lipid Res. 49 (2008) 1562-1568
-
(2008)
J. Lipid Res.
, vol.49
, pp. 1562-1568
-
-
Murano, I.1
Barbatelli, G.2
Parisani, V.3
Latini, C.4
Muzzonigro, G.5
Castellucci, M.6
Cinti, S.7
-
6
-
-
67650242164
-
Impaired preadipocyte differentiation in human abdominal obesity: role of Wnt, tumor necrosis factor-alpha, and inflammation
-
Isakson P., Hammarstedt A., Gustafson B., and Smith U. Impaired preadipocyte differentiation in human abdominal obesity: role of Wnt, tumor necrosis factor-alpha, and inflammation. Diabetes 58 (2009) 1550-1557
-
(2009)
Diabetes
, vol.58
, pp. 1550-1557
-
-
Isakson, P.1
Hammarstedt, A.2
Gustafson, B.3
Smith, U.4
-
7
-
-
33845926925
-
Committed subcutaneous preadipocytes are reduced in human obesity
-
Tchoukalova Y., Koutsari C., and Jensen M. Committed subcutaneous preadipocytes are reduced in human obesity. Diabetologia 50 (2007) 151-157
-
(2007)
Diabetologia
, vol.50
, pp. 151-157
-
-
Tchoukalova, Y.1
Koutsari, C.2
Jensen, M.3
-
8
-
-
0021014504
-
Impact of obesity on metabolism in men and women. Importance of regional adipose tissue distribution
-
Krotkiewski M., Bjorntorp P., Sjostrom L., and Smith U. Impact of obesity on metabolism in men and women. Importance of regional adipose tissue distribution. J. Clin. Invest. 72 (1983) 1150-1162
-
(1983)
J. Clin. Invest.
, vol.72
, pp. 1150-1162
-
-
Krotkiewski, M.1
Bjorntorp, P.2
Sjostrom, L.3
Smith, U.4
-
9
-
-
44849132591
-
Dynamics of fat cell turnover in humans
-
Spalding K.L., Arner E., Westermark P.O., Bernard S., Buchholz B.A., Bergmann O., Blomqvist L., Hoffstedt J., Naslund E., Britton T., Concha H., Hassan M., Ryden M., Frisen J., and Arner P. Dynamics of fat cell turnover in humans. Nature 453 (2008) 783-787
-
(2008)
Nature
, vol.453
, pp. 783-787
-
-
Spalding, K.L.1
Arner, E.2
Westermark, P.O.3
Bernard, S.4
Buchholz, B.A.5
Bergmann, O.6
Blomqvist, L.7
Hoffstedt, J.8
Naslund, E.9
Britton, T.10
Concha, H.11
Hassan, M.12
Ryden, M.13
Frisen, J.14
Arner, P.15
-
10
-
-
49449092403
-
Identification and characterization of metabolically benign obesity in humans
-
Stefan N., Kantartzis K., Machann J., Schick F., Thamer C., Rittig K., Balletshofer B., Machicao F., Fritsche A., and Haring H.U. Identification and characterization of metabolically benign obesity in humans. Arch. Intern. Med. 168 (2008) 1609-1616
-
(2008)
Arch. Intern. Med.
, vol.168
, pp. 1609-1616
-
-
Stefan, N.1
Kantartzis, K.2
Machann, J.3
Schick, F.4
Thamer, C.5
Rittig, K.6
Balletshofer, B.7
Machicao, F.8
Fritsche, A.9
Haring, H.U.10
-
11
-
-
34547699606
-
Metabolically healthy but obese women have an intermediate cardiovascular risk profile between healthy nonobese women and obese insulin-resistant women
-
Marini M.A., Succurro E., Frontoni S., Hribal M.L., Andreozzi F., Lauro R., Perticone F., and Sesti G. Metabolically healthy but obese women have an intermediate cardiovascular risk profile between healthy nonobese women and obese insulin-resistant women. Diabetes Care 30 (2007) 2145-2147
-
(2007)
Diabetes Care
, vol.30
, pp. 2145-2147
-
-
Marini, M.A.1
Succurro, E.2
Frontoni, S.3
Hribal, M.L.4
Andreozzi, F.5
Lauro, R.6
Perticone, F.7
Sesti, G.8
-
12
-
-
34247636362
-
PPAR gamma 2 prevents lipotoxicity by controlling adipose tissue expandability and peripheral lipid metabolism
-
Medina-Gomez G., Gray S.L., Yetukuri L., Shimomura K., Virtue S., Campbell M., Curtis R.K., Jimenez-Linan M., Blount M., Yeo G.S., Lopez M., Seppanen-Laakso T., Ashcroft F.M., Oresic M., and Vidal-Puig A. PPAR gamma 2 prevents lipotoxicity by controlling adipose tissue expandability and peripheral lipid metabolism. PLoS Genet. 3 (2007) e64
-
(2007)
PLoS Genet.
, vol.3
-
-
Medina-Gomez, G.1
Gray, S.L.2
Yetukuri, L.3
Shimomura, K.4
Virtue, S.5
Campbell, M.6
Curtis, R.K.7
Jimenez-Linan, M.8
Blount, M.9
Yeo, G.S.10
Lopez, M.11
Seppanen-Laakso, T.12
Ashcroft, F.M.13
Oresic, M.14
Vidal-Puig, A.15
-
14
-
-
0031944785
-
The metabolically obese, normal-weight individual revisited
-
Ruderman N., Chisholm D., Pi-Sunyer X., and Schneider S. The metabolically obese, normal-weight individual revisited. Diabetes 47 (1998) 699-713
-
(1998)
Diabetes
, vol.47
, pp. 699-713
-
-
Ruderman, N.1
Chisholm, D.2
Pi-Sunyer, X.3
Schneider, S.4
-
16
-
-
34547106324
-
Tumor necrosis factor alpha (TNFalpha) stimulates Map4k4 expression through TNFalpha receptor 1 signaling to c-Jun and activating transcription factor 2
-
Tesz G.J., Guilherme A., Guntur K.V., Hubbard A.C., Tang X., Chawla A., and Czech M.P. Tumor necrosis factor alpha (TNFalpha) stimulates Map4k4 expression through TNFalpha receptor 1 signaling to c-Jun and activating transcription factor 2. J. Biol. Chem. 282 (2007) 19302-19312
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 19302-19312
-
-
Tesz, G.J.1
Guilherme, A.2
Guntur, K.V.3
Hubbard, A.C.4
Tang, X.5
Chawla, A.6
Czech, M.P.7
-
17
-
-
33646934768
-
Cytokines promote Wnt signaling and inflammation and impair the normal differentiation and lipid accumulation in 3T3-L1 preadipocytes
-
Gustafson B., and Smith U. Cytokines promote Wnt signaling and inflammation and impair the normal differentiation and lipid accumulation in 3T3-L1 preadipocytes. J. Biol. Chem. 281 (2006) 9507-9516
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 9507-9516
-
-
Gustafson, B.1
Smith, U.2
-
18
-
-
34250748977
-
Tumour necrosis factor-alpha inhibits adipogenesis via a beta-catenin/TCF4(TCF7L2)-dependent pathway
-
Cawthorn W.P., Heyd F., Hegyi K., and Sethi J.K. Tumour necrosis factor-alpha inhibits adipogenesis via a beta-catenin/TCF4(TCF7L2)-dependent pathway. Cell Death Differ. 14 (2007) 1361-1373
-
(2007)
Cell Death Differ.
, vol.14
, pp. 1361-1373
-
-
Cawthorn, W.P.1
Heyd, F.2
Hegyi, K.3
Sethi, J.K.4
-
19
-
-
0038660699
-
Preadipocyte conversion to macrophage. Evidence of plasticity
-
Charriere G., Cousin B., Arnaud E., Andre M., Bacou F., Penicaud L., and Casteilla L. Preadipocyte conversion to macrophage. Evidence of plasticity. J. Biol. Chem. 278 (2003) 9850-9855
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 9850-9855
-
-
Charriere, G.1
Cousin, B.2
Arnaud, E.3
Andre, M.4
Bacou, F.5
Penicaud, L.6
Casteilla, L.7
-
20
-
-
34247551878
-
Wnt-signaling is maintained and adipogenesis inhibited by TNFalpha but not MCP-1 and resistin
-
Hammarstedt A., Isakson P., Gustafson B., and Smith U. Wnt-signaling is maintained and adipogenesis inhibited by TNFalpha but not MCP-1 and resistin. Biochem. Biophys. Res. Commun. 357 (2007) 700-706
-
(2007)
Biochem. Biophys. Res. Commun.
, vol.357
, pp. 700-706
-
-
Hammarstedt, A.1
Isakson, P.2
Gustafson, B.3
Smith, U.4
-
21
-
-
0035851187
-
PPARgamma: a nuclear regulator of metabolism, differentiation, and cell growth
-
Rosen E.D., and Spiegelman B.M. PPARgamma: a nuclear regulator of metabolism, differentiation, and cell growth. J. Biol. Chem. 276 (2001) 37731-37734
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 37731-37734
-
-
Rosen, E.D.1
Spiegelman, B.M.2
-
22
-
-
0031762908
-
Omental and subcutaneous adipose tissues of obese subjects release interleukin-6: depot difference and regulation by glucocorticoid
-
Fried S.K., Bunkin D.A., and Greenberg A.S. Omental and subcutaneous adipose tissues of obese subjects release interleukin-6: depot difference and regulation by glucocorticoid. J. Clin. Endocrinol. Metab. 83 (1998) 847-850
-
(1998)
J. Clin. Endocrinol. Metab.
, vol.83
, pp. 847-850
-
-
Fried, S.K.1
Bunkin, D.A.2
Greenberg, A.S.3
-
23
-
-
2042480671
-
Comparison of the release of adipokines by adipose tissue, adipose tissue matrix, and adipocytes from visceral and subcutaneous abdominal adipose tissues of obese humans
-
Fain J.N., Madan A.K., Hiler M.L., Cheema P., and Bahouth S.W. Comparison of the release of adipokines by adipose tissue, adipose tissue matrix, and adipocytes from visceral and subcutaneous abdominal adipose tissues of obese humans. Endocrinology 145 (2004) 2273-2282
-
(2004)
Endocrinology
, vol.145
, pp. 2273-2282
-
-
Fain, J.N.1
Madan, A.K.2
Hiler, M.L.3
Cheema, P.4
Bahouth, S.W.5
-
24
-
-
0036309971
-
Regional differences in the response of human pre-adipocytes to PPARgamma and RXRalpha agonists
-
Sewter C.P., Blows F., Vidal-Puig A., and O'Rahilly S. Regional differences in the response of human pre-adipocytes to PPARgamma and RXRalpha agonists. Diabetes 51 (2002) 718-723
-
(2002)
Diabetes
, vol.51
, pp. 718-723
-
-
Sewter, C.P.1
Blows, F.2
Vidal-Puig, A.3
O'Rahilly, S.4
-
25
-
-
0345374579
-
Minireview: weapons of lean body mass destruction: the role of ectopic lipids in the metabolic syndrome
-
Unger R.H. Minireview: weapons of lean body mass destruction: the role of ectopic lipids in the metabolic syndrome. Endocrinology 144 (2003) 5159-5165
-
(2003)
Endocrinology
, vol.144
, pp. 5159-5165
-
-
Unger, R.H.1
-
26
-
-
33751545838
-
A placebo-controlled trial of pioglitazone in subjects with nonalcoholic steatohepatitis
-
Belfort R., Harrison S.A., Brown K., Darland C., Finch J., Hardies J., Balas B., Gastaldelli A., Tio F., Pulcini J., Berria R., Ma J.Z., Dwivedi S., Havranek R., Fincke C., DeFronzo R., Bannayan G.A., Schenker S., and Cusi K. A placebo-controlled trial of pioglitazone in subjects with nonalcoholic steatohepatitis. N. Engl. J. Med. 355 (2006) 2297-2307
-
(2006)
N. Engl. J. Med.
, vol.355
, pp. 2297-2307
-
-
Belfort, R.1
Harrison, S.A.2
Brown, K.3
Darland, C.4
Finch, J.5
Hardies, J.6
Balas, B.7
Gastaldelli, A.8
Tio, F.9
Pulcini, J.10
Berria, R.11
Ma, J.Z.12
Dwivedi, S.13
Havranek, R.14
Fincke, C.15
DeFronzo, R.16
Bannayan, G.A.17
Schenker, S.18
Cusi, K.19
-
27
-
-
12944325312
-
Improved insulin sensitivity and adipose tissue dysregulation after short-term treatment with pioglitazone in non-diabetic, insulin-resistant subjects
-
Hammarstedt A., Sopasakis V.R., Gogg S., Jansson P.A., and Smith U. Improved insulin sensitivity and adipose tissue dysregulation after short-term treatment with pioglitazone in non-diabetic, insulin-resistant subjects. Diabetologia 48 (2005) 96-104
-
(2005)
Diabetologia
, vol.48
, pp. 96-104
-
-
Hammarstedt, A.1
Sopasakis, V.R.2
Gogg, S.3
Jansson, P.A.4
Smith, U.5
-
28
-
-
33646346627
-
Mice lacking adiponectin show decreased hepatic insulin sensitivity and reduced responsiveness to peroxisome proliferator-activated receptor gamma agonists
-
Nawrocki A.R., Rajala M.W., Tomas E., Pajvani U.B., Saha A.K., Trumbauer M.E., Pang Z., Chen A.S., Ruderman N.B., Chen H., Rossetti L., and Scherer P.E. Mice lacking adiponectin show decreased hepatic insulin sensitivity and reduced responsiveness to peroxisome proliferator-activated receptor gamma agonists. J. Biol. Chem. 281 (2006) 2654-2660
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 2654-2660
-
-
Nawrocki, A.R.1
Rajala, M.W.2
Tomas, E.3
Pajvani, U.B.4
Saha, A.K.5
Trumbauer, M.E.6
Pang, Z.7
Chen, A.S.8
Ruderman, N.B.9
Chen, H.10
Rossetti, L.11
Scherer, P.E.12
-
29
-
-
0036851817
-
Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase
-
Yamauchi T., Kamon J., Minokoshi Y., Ito Y., Waki H., Uchida S., Yamashita S., Noda M., Kita S., Ueki K., Eto K., Akanuma Y., Froguel P., Foufelle F., Ferre P., Carling D., Kimura S., Nagai R., Kahn B.B., and Kadowaki T. Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase. Nat. Med. 8 (2002) 1288-1295
-
(2002)
Nat. Med.
, vol.8
, pp. 1288-1295
-
-
Yamauchi, T.1
Kamon, J.2
Minokoshi, Y.3
Ito, Y.4
Waki, H.5
Uchida, S.6
Yamashita, S.7
Noda, M.8
Kita, S.9
Ueki, K.10
Eto, K.11
Akanuma, Y.12
Froguel, P.13
Foufelle, F.14
Ferre, P.15
Carling, D.16
Kimura, S.17
Nagai, R.18
Kahn, B.B.19
Kadowaki, T.20
more..
-
30
-
-
0032520921
-
Troglitazone increases the number of small adipocytes without the change of white adipose tissue mass in obese Zucker rats
-
Okuno A., Tamemoto H., Tobe K., Ueki K., Mori Y., Iwamoto K., Umesono K., Akanuma Y., Fujiwara T., Horikoshi H., Yazaki Y., and Kadowaki T. Troglitazone increases the number of small adipocytes without the change of white adipose tissue mass in obese Zucker rats. J. Clin. Invest. 101 (1998) 1354-1361
-
(1998)
J. Clin. Invest.
, vol.101
, pp. 1354-1361
-
-
Okuno, A.1
Tamemoto, H.2
Tobe, K.3
Ueki, K.4
Mori, Y.5
Iwamoto, K.6
Umesono, K.7
Akanuma, Y.8
Fujiwara, T.9
Horikoshi, H.10
Yazaki, Y.11
Kadowaki, T.12
-
31
-
-
0035430576
-
Effects of pioglitazone on adipose tissue remodeling within the setting of obesity and insulin resistance
-
de Souza C.J., Eckhardt M., Gagen K., Dong M., Chen W., Laurent D., and Burkey B.F. Effects of pioglitazone on adipose tissue remodeling within the setting of obesity and insulin resistance. Diabetes 50 (2001) 1863-1871
-
(2001)
Diabetes
, vol.50
, pp. 1863-1871
-
-
de Souza, C.J.1
Eckhardt, M.2
Gagen, K.3
Dong, M.4
Chen, W.5
Laurent, D.6
Burkey, B.F.7
-
32
-
-
43149112800
-
Adipogenic capacity and the susceptibility to type 2 diabetes and metabolic syndrome
-
Wang M.Y., Grayburn P., Chen S., Ravazzola M., Orci L., and Unger R.H. Adipogenic capacity and the susceptibility to type 2 diabetes and metabolic syndrome. Proc. Natl. Acad. Sci. U. S. A. 105 (2008) 6139-6144
-
(2008)
Proc. Natl. Acad. Sci. U. S. A.
, vol.105
, pp. 6139-6144
-
-
Wang, M.Y.1
Grayburn, P.2
Chen, S.3
Ravazzola, M.4
Orci, L.5
Unger, R.H.6
|