Surgical angiogenesis: A new approach to maintain osseous viability in xenotransplantation

Xenotransplantation

Volumn 17, Issue 1, 2010, Pages 38-47

  Chung, Yang Guk ^a,b   Bishop, Allen T ^a   Giessler, Goetz A ^a,c   Suzuki, Osami ^d   Platt, Jeffrey L ^a   Pelzer, Michael ^c   Friedrich, Patricia F ^a   Kremer, Thomas ^a,c  

^a MAYO CLINIC   (United States)

^b The Catholic University of Korea   (South Korea)

^c UNIVERSITY OF HEIDELBERG   (Germany)

^d HIROSHIMA UNIVERSITY   (Japan)

Author keywords

Microsurgery; Surgical angiogenesis; Vascularized bone graft; Xenotransplantation

Indexed keywords

TACROLIMUS;

ANALYSIS OF VARIANCE; ANGIOGENESIS; ANIMAL CELL; ARTICLE; BLOOD VESSEL SHUNT; BONE BLOOD FLOW; BONE GRAFT; BONE NECROSIS; BONE REMODELING; BONE TRANSPLANTATION; CAPILLARY DENSITY; CELL VIABILITY; CONTROLLED STUDY; GRAFT SURVIVAL; HAMSTER; IMMUNOMODULATION; IMMUNOSUPPRESSIVE TREATMENT; MICROANGIOGRAPHY; MICROSURGERY; MICROVASCULATURE; NONHUMAN; OSTEOCYTE; PRIORITY JOURNAL; RAT; RECIPIENT; REVASCULARIZATION; XENOTRANSPLANTATION;

ANASTOMOSIS, SURGICAL; ANIMALS; BONE TRANSPLANTATION; CRICETINAE; FEMUR; GRAFT REJECTION; GRAFT SURVIVAL; HUMANS; MALE; MESOCRICETUS; NEOVASCULARIZATION, PHYSIOLOGIC; RANDOM ALLOCATION; RATS; RATS, INBRED LEW; REGIONAL BLOOD FLOW; TRANSPLANTATION, HETEROLOGOUS;

EID: 76349084075     PISSN: 0908665X     EISSN: 13993089     Source Type: Journal    
DOI: 10.1111/j.1399-3089.2009.00563.x     Document Type: Article

References (48)

1. Capanna R, Campanacci DA, Belot N et al. A new reconstructive technique for intercalary defects of long bones: the association of massive allograft with vascularized fibular autograft. Long-term results and comparison with alternative techniques. Orthop Clin North Am 2007 38 : 51 60, Vi.
2. Heisel C, Breusch SJ, Schmid G, Bernd L. Lower limb salvage surgery with MUTARS endoprostheses: 2 to 7 year results. Acta Orthop Belg 2004 70 : 142 147.
3. Heisel C, Kinkel S, Bernd L, Ewerbeck V. Megaprostheses for the treatment of malignant bone tumours of the lower limbs. Int Orthop 2006 30 : 452 457.
4. Natarajan MV, Balasubramanian N, Jayasankar V, Sameer M. Endoprosthetic reconstruction using total femoral custom mega prosthesis in malignant bone tumours. Int Orthop 2009 33 : 1359 1363.
5. Schurmann M, Gradl G, Andress HJ et al. Metastatic lesions of the humerus treated with the isoelastic diaphysis prosthesis. Clin Orthop Relat Res 2000 380 : 204 214.
6. Bishop AT. Vascularized bone grafting. In Green D, Hotchkiss R, Pederson W, eds. Green's Operative Hand Surgery, Vol. 2. New York : Churchill Livingstone, 1999 : 1221 1250.
7. Muscolo DL, Ayerza MA, Aponte-Tinao L et al. Intercalary femur and tibia segmental allografts provide an acceptable alternative in reconstructing tumor resections. Clin Orthop Relat Res 2004 426 : 97 102.
8. Muscolo DL, Ayerza MA, Aponte-Tinao LA. Massive allograft use in orthopedic oncology. Orthop Clin North Am 2006 37 : 65 74.
9. Ortiz-Cruz E, Gebhardt MC, Jennings LC et al. The results of transplantation of intercalary allografts after resection of tumors. A long-term follow-up study. J Bone Joint Surg Am 1997 79 : 97 106.
10. Lee KS, Park JW. Free vascularized osteocutaneous fibular graft to the tibia. Microsurgery 1999 19 : 141 147.
11. Doi K, Akino T, Shigetomi M et al. Vascularized bone allografts: review of current concepts. Microsurgery 1994 15 : 831 841.
12. Hofmann GO, Kirschner MH, Brauns L et al. Vascularized knee joint transplantation in man: a report on the first cases. Transpl Int 1998 11 (Suppl. 1 S487 S490.
13. Hofmann GO, Kirschner MH, Wagner FD et al. Allogeneic vascularized transplantation of human femoral diaphyses and total knee joints - first clinical experiences. Transplant Proc 1998 30 : 2754 2761.
14. Diefenbeck M, Wagner F, Kirschner MH et al. Outcome of allogeneic vascularized knee transplants. Transpl Int 2007 20 : 410 418.
15. Siemionow M, Klimczak A. Tolerance and future directions for composite tissue allograft transplants: part II. Plast Reconstr Surg 2009 123 : 7e 17e.
16. Siemionow M, Nasir S. Impact of donor bone marrow on survival of composite tissue allografts. Ann Plast Surg 2008 60 : 455 462.
17. Woodruff MFA, Woodruff HG. The transplantation of normal tissue: with special reference to auto- and hemotransplants of thyroid and spleen in the anterior chamber of the eye, and subcutaneously, in guinea-pig. Philos Trans R Soc Lond (Biol) 1950 234 : 559 581.
18. Giessler GA, Zobitz M, Friedrich PF, Bishop AT. Host-derived neoangiogenesis with short-term immunosuppression allows incorporation and remodeling of vascularized diaphyseal allogeneic rabbit femur transplants. J Orthop Res 2008 27 : 763 770.
19. Ohno T, Pelzer M, Larsen M et al. Host-derived angiogenesis maintains bone blood flow after withdrawal of immunosuppression. Microsurgery 2007 27 : 657 663.
20. Pelzer M, Larsen M, Chung YG et al. Short-term immunosuppression and surgical neoangiogenesis with host vessels maintains long-term viability of vascularized bone allografts. J Orthop Res 2007 25 : 370 377.
21. Sheetz KK, Bishop AT, Berger RA. The arterial blood supply of the distal radius and ulna and its potential use in vascularized pedicled bone grafts. J Hand Surg Am 1995 20 : 902 914.
22. Hoerbelt R, Madsen JC. Feasibility of xeno-transplantation. Surg Clin North Am 2004 84 : 289 307.
23. Platt JL. New directions for organ transplantation. Nature 1998 392 : 11 17.
24. Lawson JH, Platt JL. Molecular barriers to xenotransplantation. Transplantation 1996 62 : 303 310.
25. Platt JL, Holzknecht ZE. Porcine platelet antigens recognized by human xenoreactive natural antibodies. Transplantation 1994 57 : 327 335.
26. Platt JL. Zoonosis in xenotransplantation. Transplant Proc 2000 32 : 1551.
27. Platt JL, Vercellotti GM, Dalmasso AP et al. Transplantation of discordant xenografts: a review of progress. Immunol Today 1990 11 : 450 456.
28. Schuurman HJ, Cheng J, Lam T. Pathology of xenograft rejection: a commentary. Xenotransplantation 2003 10 : 293 299.
29. Tanabe YN, Randolph MA, Shimizu A, Lee WP. Xenotransplantation model for vascularized musculoskeletal tissues in rodents. Microsurgery 2000 20 : 59 64.
30. Suzuki O, Bishop AT, Sunagawa T et al. Augmented surgical angiogenesis in necrotic bone: correction of avascular necrosis with vascular endothelial growth factor (VEGF). Microsurgery 2004 24 : 85 91.
31. Platt JL. Genetic therapies and xenotransplantation. Expert Opin Investig Drugs 1999 8 : 1653 1662.
32. Tonomura N, Shimizu A, Wang S et al. Pig islet xenograft rejection in a mouse model with an established human immune system. Xenotransplantation 2008 15 : 129 135.
33. Abraham EJ, Kodama S, Lin JC et al. Human pancreatic islet-derived progenitor cell engraftment in immunocompetent mice. Am J Pathol 2004 164 : 817 830.
34. Soncini M, Signoroni PB, Bailo M et al. Use of highly sensitive mitochondrial probes to detect microchimerism in xenotransplantation models. Xenotransplantation 2006 13 : 80 85.
35. Muramatsu K, Kuriyama R, Taguchi T. Intragraft chimerism following composite tissue allograft. J Surg Res 2008 157 : 129 135.
36. Pelzer M, Larsen M, Friedrich PF et al. Repopulation of vascularized bone allotransplants with recipient-derived cells: detection by laser capture microdissection and real-time PCR. J Orthop Res 2009 27 : 1514 1520.
37. Feng S. Long-term management of immunosuppression after pediatric liver transplantation: is minimization or withdrawal desirable or possible or both? Curr Opin Organ Transplant 2008 13 : 506 512.
38. Korngold B, Sprent J. Lethal graft-versus-host disease after bone marrow transplantation across minor histocompatibility barriers in mice. Prevention by removing mature T cells from marrow. J Exp Med 1978 148 : 1687 1698.
39. Kernan NA, Bartsch G, Ash RC et al. Analysis of 462 transplantations from unrelated donors facilitated by the National Marrow Donor Program. N Engl J Med 1993 328 : 593 602.
40. Jones NF. Concerns about human hand transplantation in the 21st century. J Hand Surg Am 2002 27 : 771 787.
41. Rohrich RJ, Longaker MT, Cunningham B. On the ethics of composite tissue allotransplantation (facial transplantation). Plast Reconstr Surg 2006 117 : 2071 2073.
42. Yang YG, Sykes M. Xenotransplantation: current status and a perspective on the future. Nat Rev Immunol 2007 7 : 519 531.
43. Komatsu K, Youm W, Konishi H et al. Prolonged survival of hamster-to-rat pulmonary xenografts by tacrolimus (FK506) and cyclophosphamide. J Heart Lung Transplant 1996 15 : 722 727.
44. Mollevi DG, Ginesta MM, Domenech P et al. Hemostatic status in long-term surviving xenografts. Surgery 2006 139 : 775 781.
45. Tabata T, De Perrot M, Keshavjee S et al. Accommodation after lung xenografting from hamster to rat. Transplantation 2003 75 : 607 612.
46. Suhr BD, Black SM, Guzman-Paz M et al. Inhibition of the membrane attack complex of complement for induction of accommodation in the hamster-to-rat heart transplant model. Xenotransplantation 2007 14 : 572 579.
47. Van den bogaerde J, Aspinall R, Wang MW et al. Induction of long-term survival of hamster heart xenografts in rats. Transplantation 1991 52 : 15 20.
48. Giessler GA, Gades NM, Friedrich PF, Bishop AT. Severe tacrolimus toxicity in rabbits. Exp Clin Transplant 2007 5 : 590 595.