Comparison of topical glyceryl trinitrate with diltiazem ointment for the treatment of chronic anal fissure : A randomized clinical trial

Acta Chirurgica Belgica

Volumn 109, Issue 6, 2009, Pages 727-730

  Sanei, B ^a   Mahmoodieh, M ^a   Masoudpour, H ^a  

^a ISFAHAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Anal fissure; Topical ointment

Indexed keywords

EID: 76249131966     PISSN: 00015458     EISSN: 25770160     Source Type: Journal    
DOI: 10.1080/00015458.2009.11680524     Document Type: Article

References (17)

1. GOLIGHER J. C. Surgery of the Anus, Rectum and Colon, 5th edn. : Bailliere Tindall, 1984.
2. CORMAN M. L. Anal fissures. In : CORMAN M. L. (ed.). Colon & Rectal Surgery, 5th edn. : Lippincott Williams & Wilkins, 2005 : 255-277.
3. LINDSEY I., JONES O. M., CUNNINGHAM C., MORTENSEN N. J. Chronic anal fissure. Br J Surg, 2004, 91 : 270-279.
4. RICHARD C. S., GREGOIRE R. et al. Internal sphincterotomy is superior to topical nitroglycerin in the treatment of chronic anal fissure : results of a randomized, controlled trial by the Canadian Colorectal Surgical Trials Group. Dis Colon Rectum, 2000, 43 : 1048-1057.
5. GARCIA-AGUILAR J., BELMONTE C., WONG W. D., LOWRY A. C., MADOFF R. D. Open v. Closed sphincterotomy for chronic anal fissure : Long-term results. Dis Colon Rectum, 1996, 39 : 440-443.
6. BHARDWAJ R., PARKER M. C. Modern perspectives in the treatment of chronic anal fissures. Ann R Coll Surg Engl, 2007, 89 : 472-478.
7. LUND J. N., SCHOLEFIELD J. H. A randomized, prospective, double blind, place-controlled trial of glyceryl trinitrate ointment in the treatment of anal fissure. Lancet, 1997, 349 : 11-14.
8. ANTROPOLI C. et al. Nifedipine for local use in conservative treatment of anal fissures : preliminary results of a multi-centre study. Dis Colon Rectum, 1999, 42 :1011-1015.
9. PANAGIOTIS K. et al. Topical 0.5% nifedipine v. lateral internal sphincterotomy for the treatment of chronic anal fissure : long-term follow-up. Int J Colorectal Dis,2006, 21 : 179-183.
10. CARAPETI E. A., KAMM M. A., PHILLIPS R. K. Topical diltiazem and bethanechol decrease anal sphincter pressure and heal anal fissures without side effects. Dis Colon Rectum, 2000, 43 : 1359-1362.
11. KNIGHT J. S., BIRK M., FAROUK R. Topical diltiazem ointment in the treatment of chronic anal fissure. Br J Surg, 2001, 88 : 553-556.
12. OETTLE G. J. Glyceryl trinitrate v. Sphincterotomy for treatment of chronic fissure-in-ano. A randomized controlled trial. Dis Col Rect, 1997, 40 : 1318-1320.
13. RICHARD C. S., GREGOIRE R., PLEWES E. A. et al. Internal sphincterotomy is superior to topical nitroglycerin in the treatment of chronic anal fissure. Dis Col Rect,2000, 43 : 1048-1055.
14. KENNEDY M. L., SOWTER S. et al. Glyceryl trinitrate ointment for the treatment of chronic anal fissure, results of a placebo-controlled trial and long-term follow-up. Dis Col Rect, 1999, 42 : 1000-1006.
15. PALAZZO F. F., KAPUR S. et al. Glyceryl trinitrate treatment of chronic fissure-in-ano : one year's experience with 0.5% GTN paste. J Roy Coll Surg Edinb, 2000, 45 : 168-170.
16. HASEGAWA H., RADLEY S. et al. An audit of topical glyceryl trinitrate for treatment of fissure-in-ano. Ann Roy Coll Surg Engl, 2000, 82 : 27-30.
17. SAJID M. S., RIMPLE J., CHEEK E., BAIG M. K. The efficacy of diltiazem and glyceryl trinitrate for the medical management of chronic anal fissure : a meta-analysis. Int J Colorectal Dis, 2008, 23 : 1-6. (Pubitemid 350142353)