The effects of sibutramine on the microstructure of eating behaviour and energy expenditure in obese women

Journal of Psychopharmacology

Volumn 24, Issue 1, 2010, Pages 99-109

  Halford, J C G ^a   Boyland, E J ^a   Cooper, S J ^a   Dovey, T M ^a,b   Huda, M S B ^c   Dourish, C T ^d   Dawson, G R ^d   Wilding, J P H ^c  

^a UNIVERSITY OF LIVERPOOL   (United Kingdom)

^b UNIVERSITY HOSPITAL AINTREE   (United Kingdom)

^c STAFFORDSHIRE UNIVERSITY   (United Kingdom)

^d UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Cumulative intake; Eating rate; Obesity; Satiety; Sibutramine

Indexed keywords

PLACEBO; SIBUTRAMINE;

ADULT; APPETITE; ARTICLE; BODY MASS; CALORIMETRY; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; DOUBLE BLIND PROCEDURE; DRUG EFFECT; ENERGY BALANCE; ENERGY EXPENDITURE; FEEDING BEHAVIOR; FEMALE; FOOD INTAKE; HUMAN; MEAL; OBESITY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RESPIRATORY QUOTIENT; STOMACH DISEASE; SYSTOLIC BLOOD PRESSURE; UNSPECIFIED SIDE EFFECT;

ADULT; APPETITE DEPRESSANTS; CROSS-OVER STUDIES; CYCLOBUTANES; DOSE-RESPONSE RELATIONSHIP, DRUG; DOUBLE-BLIND METHOD; ENERGY METABOLISM; FEEDING BEHAVIOR; FEMALE; HUMANS; HUNGER; MIDDLE AGED; OBESITY; SATIETY RESPONSE; TIME FACTORS;

EID: 76249091342     PISSN: 02698811     EISSN: 14617285     Source Type: Journal    
DOI: 10.1177/0269881108095195     Document Type: Article

References (41)

1. Barkeling, B., Ekman, S., Rössner, S. (1992) Eating behaviour in obese and normal weight 11-year-old children. Int J Obes 16 (5). 355-360.
2. Barkeling, B., Elfhag, K., Rooth, P., Rössner, S. (2003) Short-term effects of sibutramine (ReductilTM) on appetite and eating behaviour and the long-term therapeutic outcome. Int J Obes 27: 693-700.
3. Benporat, M., Sideman, S., Bursztein, S. (1983) Energy-Metabolism Rate-Equation for fasting and postabsorptive subjects. Am J Physiol 244: R764 - R769.
4. Blundell, JE (1977) Is there a role for serotonin (5-hydroxytryptamine) in feeding. Int J Obes 1: 15-42.
5. Chapelot, D., Mamonier, C., Thomas, F., Hanotin, C. (2000) Modalities of the food intake-reducing effect of sibutramine in humans. Physiol Behav 68: 299-308.
6. Erondu, N., Gantz, I., Musser, B., Suryawanshi, S., Mallick, M., Addy, C., et al. (2006) Neuropeptide Y5 receptor antagonist does not induce clinically meaningful weight loss in overweight and obese adults. Cell Metab 4: 275-282.
7. Gray, RW, French, SJ, Robinson, TM, Yeomans, M. (2002) Dissociation of the effects of preload volume and energy content on subjective appetite and food intake. Physiol Behav 76: 57-64.
8. Green, SM, Delargy, HJ, Joanes, S., Blundell, JE (1997) A satiety quotient: a formulation to assess the satiating effect of food. Appetite 29: 291-304.
9. Guss, JL, Kissileff, HR (2000) Microstructural analysis of human ingestive patterns: from description to mechanistic hypotheses. Neurosci Biobehav Rev 24: 261-268.
10. Halford, JCH, Harrold, JA, Boyland, EJ, Lawton, CL, Blundell, JE (2007) Serotonergic drugs: effects on appetite expression and use for the treatment of obesity. Drugs 67: 27-55.
11. Hansen, DL, Toubro, S., Stock, MJ, Macdonald, IA, Astrup, A. (1998) Thermogenic effects of sibutramine in humans. Am J Clin Nutr 68: 1180-1186.
12. Heal, DJ, Aspely, A., Prow, MR, Jackson, HC, Martin, KF, Cheetham, SC (1998) Sibutramine: a novel anti-obesity drug. A review of the pharmacological evidence to differentiate from d-amphetamine and d-fenfluramine. Int J Obes 22 (Suppl. 1). s18 - s28.
13. Hill, AJ, Rogers, PJ, Blundell, JE (1995) Techniques for the experimental measurement of human eating behaviour and food intake: a practical guide. Int J Obes 19: 361-375.
14. Hind, ID, Mangham, JE, Ghani, SP, Haddock, RE, Garratt, CJ, Jones, RW (1999) Sibutramine pharmacokinetics in young and elderly healthy subjects. Eur J Clin Pharmacol 54: 847-849.
15. Hubel, R., Laessle, RG, Lehrke, S., Jass, J. (2006) Laboratory measurement of cumulative food intake in humans: results on the reliability. Appetite 46: 57-62.
16. Jordan, HA, Wieland, WF, Zebley, SP, Stellar, E., Stunkard, AJ (1966) Direct measurement of food intake in man: a method for objective study of eating behavior. Psychosom Med 28: 836-842.
17. Kissileff, HR, Klingsberg, G., Van Itallie, TB (1980) Universal eating monitor for the continuous recording of solid or liquid consumption in man. Am J Physiol 238: 14-22.
18. Kissileff, HR, Thornton, J., Becker, E. (1982) A quadratic equation adequately describes the cumulative food intake curve in man. Appetite 3: 255-272.
19. Kissileff, HR, Wentzlaff, TH, Guss, JL, Walsh, BT, Devlin, MJ, Thornton, JC (1996) A direct measure of satiety disturbance in patients with bulimia nervosa. Physiol Behav 60: 1077-1085.
20. Laessle, RG, Uhl, H., Lindel, B. (2001 a) Parental influences on eating behaviour in obese and nonobese preadolescents. Int J Eat Disord 30: 447-453. (Pubitemid 33055066)
21. Laessle, RG, Uhl, H., Lindel, B., M1/4ller, A. (2001 b) Parental influences on eating behaviour in obese and nonobese children. Int J Obes 25 (Suppl. 1). s60 - s62.
22. Lindgren, AC, Barkeling, B., Hägg, A., Ritzén, EM, Marcus, C., Rössner, S. (2000) Eating behaviour in Prader-Willi syndrome, normal weight and obese control groups. J Pediatr 137: 50-55.
23. Mansell, PI, Macdonald, IA (1990) Reappraisal of the weir equation for the calculation of metabolic rate. Am J Physiol 258: 1347-1354.
24. Meyer, JE, Pudel, V. (1972) Experimental studies on food-intake in obese and normal subjects. J Psychosom Res 16: 305-308.
25. Näslund, E., Gutniak, M., Skogar, S., Rössner, S., Hellström, PM (1998) Glucagon-like peptide 1 increases the period of postprandial satiety and slows gastric emptying in obese men. Am J Clin Nutr 68: 525-530.
26. Robinson, TM, Gray, RW, Yeomans, MR, French, SJ (2005) Test-meal palatability alters the effects of intra-gastric fat but not carbohydrate preloads on intake and related appetite in healthy volunteers. Physiol Behav 84: 193-203.
27. Rogers, PJ, Blundell, JE (1979) Effect of anorexic drugs on food intake and the micro-structure of eating in human subjects. Psychopharmacology (Berl) 66: 159-165.
28. Rolls, BJ, Shide, DJ, Thorwart, ML, Ulbrecht, JS (1998) Sibutramine reduces food intake in non-dieting women with obesity. Obes Res 6: 1-11.
29. Seagle, HM, Bessesen, DH, Hill, JO (1998) Effects of sibutramine on resting metabolic rate and weight loss in overweight women. Obes Res 6: 115-121.
30. Stock, MJ (1997) Sibutramine: a review of the pharmacology of a novel anti-obesity agent. Int J Obes 21 (Suppl. 1). s25 - s29.
31. Stunkard, A., Coll, M., Lundquist, S., Meyers, A. (1980) Obesity and eating style. Arch Gen Psychiatry 37: 1127-1129.
32. Stunkard, A., Kaplan, D. (1977) Eating in public places: a review of report of the direct observation of eating behaviour. Int J Obes 1: 89-101.
33. Stunkard, A., Messick, S. (1985) The three-factor eating questionnaire to measure dietary restraint, disinhibition and hunger. J Psychosom Res 29: 71-83.
34. Walsh, KM, Leen, E., Lean, MEJ (1999) The effect of sibutramine on resting energy expenditure and adrenaline-induced thermogenesis. Int J Obes 23: 1009-1015.
35. Wentzlaff, TH, Guss, JL, Kissileff, HR (1995) Subjective ratings as a function of amount consumed: a preliminary report. Physiol Behav 57: 1209-1214.
36. Westerterp-Plantenga, MS (2000) Eating behaviour in humans, characterized by cumulative food intake curves - a review. Neurosci Biobehav Rev 24: 239-248.
37. Yeomans, MR (1996) Palatability and the micro-structure of feeding in humans: the appetizer effect. Appetite 27: 119-133.
38. Yeomans, MR (2000) Rating changes over the course of meals: what do they tell us about motivation to eat. Neurosci Biobehav Rev 24: 249-259.
39. Yeomans, MR, Gray, RW (1997) Effects of naltrexone on food intake and changes in subjective appetite during eating: evidence for opioid involvement in the appetizer effect. Physiol Behav 62: 15-21.
40. Yeomans, MR, Gray, RW, Mitchel, CJ, True, S. (1997) Independent effects of palatability and within-meal pauses on intake and appetite ratings in human volunteers. Appetite 29: 61-76.
41. Zelissen, PMJ, Stenlof, K., Lean, MEJ, Fogteloo, J., Keulen, ETP, Wilding, J., et al. (2005) Effect of three treatment schedules of recombinant methionyl human leptin on body weight in obese adults: a randomised placebo controlled trial. Diabetes Obes Metab 7: 755-761.