Surfactant protein B propeptide contains a saposin-like protein domain with antimicrobial activity at low pH

Journal of Immunology

Volumn 184, Issue 2, 2010, Pages 975-983

  Yang, Li ^a   Johansson, Jan ^b   Ridsdale, Ross ^a   Willander, Hanna ^b   Fitzen, Michael ^b   Akinbi, Henry T ^a   Weaver, Timothy E ^a  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^b SWEDISH UNIVERSITY OF AGRICULTURAL SCIENCES   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

SPHINGOLIPID ACTIVATOR PROTEIN; SURFACTANT PROTEIN B; ANTIINFECTIVE AGENT; PROTEIN PRECURSOR; PROTEOLIPID; SURFACTANT PROTEIN B PROPEPTIDE;

ACIDITY; AMINO TERMINAL SEQUENCE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIMICROBIAL ACTIVITY; ARTICLE; BRONCHIOLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; EPITHELIUM CELL; GENE OVEREXPRESSION; HOST RESISTANCE; INOCULATION; LUNG ALVEOLUS MACROPHAGE; LUNG LAVAGE; MOUSE; NONHUMAN; PH; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; SURVIVAL; TRANSGENIC MOUSE; ANIMAL; CHEMISTRY; IMMUNOLOGY; INNATE IMMUNITY; ISOLATION AND PURIFICATION; KLEBSIELLA PNEUMONIAE; MICROBIOLOGY; PROTEIN TERTIARY STRUCTURE; STAPHYLOCOCCUS AUREUS; TISSUE DISTRIBUTION;

ANIMALS; ANTI-BACTERIAL AGENTS; BRONCHOALVEOLAR LAVAGE FLUID; HYDROGEN-ION CONCENTRATION; IMMUNITY, INNATE; KLEBSIELLA PNEUMONIAE; MACROPHAGES, ALVEOLAR; MICE; MICE, TRANSGENIC; PROTEIN PRECURSORS; PROTEIN STRUCTURE, TERTIARY; PROTEOLIPIDS; SAPOSINS; STAPHYLOCOCCUS AUREUS; TISSUE DISTRIBUTION;

EID: 76249088372     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.0900650     Document Type: Article

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