Gene expression patterns of environmental chemicals in human cell lines using HazChem human array

Biochip Journal

Volumn 3, Issue 1, 2009, Pages 65-70

  Park, Hye Won ^a,b   Kim, Seung Jun ^a,b   Oh, Moon Ju ^a,b   Youn, Jong Pil ^a   Ha, Jung Mi ^a,b   Paul, Saswati ^b   Kim, Youn Jung ^c   Ryu, Jae Chun ^c   Hwang, Seung Yong ^a,b  

^a GenoCheck Co Ltd   (South Korea)

^b Hanyang University   (South Korea)

^c Korea Institute of Science and Technology   (South Korea)

Author keywords

Environmental hazards; Microarray; PAHs (Polycyclic Aromatic Hydrocarbons); POPs (Persistent Organic Pollutants); Toxicogenomics; VOCs (Volatile Organic Compounds)

Indexed keywords

AIR POLLUTION; AROMATIC HYDROCARBONS; AROMATIZATION; CELL CULTURE; CHEMICAL ANALYSIS; CHEMICAL CONTAMINATION; DICHLOROMETHANE; ETHYLBENZENE; EXPERIMENTS; GAS CHROMATOGRAPHY; GENE EXPRESSION; INDICATORS (CHEMICAL); ORGANIC POLLUTANTS; PLANTS (BOTANY); TRICHLOROETHYLENE; VOLATILE ORGANIC COMPOUNDS;

ENVIRONMENTAL HAZARDS; PERSISTENT ORGANIC POLLUTANTS; POLYCYCLIC AROMATICS; TOXICOGENOMICS; VOLATILE ORGANIC;

POLYCYCLIC AROMATIC HYDROCARBONS;

EID: 76149144731     PISSN: 19760280     EISSN: 20927843     Source Type: Journal    
DOI: None     Document Type: Article

References (16)

1. Fetzer, J.C. The Chemistry and Analysis of the Large Polycyclic Aromatic Hydrocarbons. New York: Wiley (2000).
2. Agency for Toxic Substances and Disease Registry (ATSDR). Toxicological Profile for Polycyclic Aromatic Hydrocarbons (PAHs). Atlanta, GA: U.S. Department of Health and Human Services, Public Health Service (1995).
3. Ritter, L., Solomon, K.R., Forget, J., Stemeroff, M. & O'Leary C. "Persistent organic pollutants". United Nations Environment Programme. http://www.chem. unep.ch/pops/ritter/en/ritteren.pdf. Retrieved on 2007-09-16.
4. Teuschler, L.K., Groten, J.P., Hertzberg, R.C., Mumtaz, M.M. & Rice, G. Environmental chemical mixtures risk assessment: current approaches and emerging issues. Comments on Toxicology 7, 453-493 (2001).
5. Wichmann, G. et al. An experimental model for the determination of immuno-modulating effects by volatile compounds. Toxicol. In Vitro 19, 685-693 (2005).
6. Witsman, F.A. et al. Toxicity of chemical mixtures: proteomic analysis of persisting liver and kidney protein alterations induced by repeated exposure of rats to JP-8 jet fuel vapor. Electrophoresis 21, 2138-2147 (2000).
7. Oh, M.J. et al. Validation of Human HazChem Array Using VOC Exposure in HL-60 Cells. Mol. Cell. Toxi-col. 1, 45-51(2008).
8. Kim, S.J. et al. Gene expression profiles of nonylphe-nol as representative EDCs in normal human human kidney HK-2 cells. Biochip J. 2, 135-140 (2008).
9. Oh, M.J. et al. Coparative analysis of gene expression patterns after exposure to nonylphenol in human cell lines. Biochip J. 2, 261-268 (2008).
10. Richard, O., Peter, E. & David, G. Pattern Classification. John Wiley & Sons, Inc (2000).
11. Waters, M. et al. Systems toxicology and the Chemical Effects in BiologicalSystems (CEBS) knowledge-base. EHP Toxicogenomics 111, 15-28 (2003).
12. Fostel, J. et al. Chemical effects in biological systems-data dictionary (CEBS-DD): a compendium of terms for the capture and integration of biological study design description, conventional phenotypes, and omics data. Toxicol. Sci. 88, 585-601 (2005).
13. De Rosa, C.T., El-Masri, H.A., Pohl, H., Cibulas, W. & Mumtaz, M.M. Implications of chemical mixtures in public health pratice. J. Toxicol. Environ. Health, Part B Crit. Rev. 7, 339-350 (2004).
14. Nuwaysir, E.F., Bittner, M., Trent, J., Barrett, J.C. & Afshari, C.A. Microarrays and toxicology: the advent of toxicogenomics. Mol. Carcinog. 24, 153-159 (1999).
15. Mosman, T. Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cyto-toxicity Assays. J. Immmunol. Meth. 65, 55-63 (1983).
16. Kim, Y.J., Lee, H.E. & Ryu, J.C. Identification of marker genes related to cardiovascular toxicity of doxorubicin & daunorubicin in Human Umbilical Vein Endothelial Cells (HUVECs). Mol. Cell. Toxicol. 3, 246-253 (2007).