Antimicrobial activity of the extracts and physalin D from Physalis alkekengi and evaluation of antioxidant potential of physalin D

Pharmaceutical Biology

Volumn 48, Issue 2, 2010, Pages 142-150

  Helvaci, S ^a   Kokdil G ^a   Kawai, M ^b   Duran, N ^c   Duran, G ^c   Guvenc A ^d  

^a MERSIN UNIVERSITY   (Turkey)

^b NAGOYA INSTITUTE OF TECHNOLOGY   (Japan)

^c MUSTAFA KEMAL UNIVERSITY   (Turkey)

^d ANKARA UNIVERSITY   (Turkey)

Author keywords

Antimicrobial activity; Antioxidant activity; Extraction; Isolation; Physalin D; Physalis alkekengi

Indexed keywords

1,1 DIPHENYL 2 PICRYLHYDRAZYL; ANTIOXIDANT; PHYSALIN D; PHYSALIS ALKEKENGI DICHLOROMETHANE EXTRACT; PHYSALIS ALKEKENGI METHANOL EXTRACT; PLANT EXTRACT; THIOBARBITURIC ACID; UNCLASSIFIED DRUG;

ANTIFUNGAL ACTIVITY; ANTIMICROBIAL ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; BROTH DILUTION; CANDIDA; CONCENTRATION RESPONSE; CONTROLLED STUDY; DISK DIFFUSION; DRUG ISOLATION; DRUG STRUCTURE; GRAM NEGATIVE INFECTION; GRAM POSITIVE BACTERIUM; HUMAN; HUMAN CELL; IC 50; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PHYSALIS; PHYSALIS ALKEKENGI; PLANT LEAF; PLANT STEM; PROTON NUCLEAR MAGNETIC RESONANCE;

ANTI-INFECTIVE AGENTS; ANTIOXIDANTS; BIPHENYL COMPOUNDS; CANDIDA; CELL LINE; FLOWERS; GRAM-NEGATIVE BACTERIA; GRAM-POSITIVE BACTERIA; HUMANS; INHIBITORY CONCENTRATION 50; MAGNETIC RESONANCE SPECTROSCOPY; MEDICINE, TRADITIONAL; MICROBIAL SENSITIVITY TESTS; PHYSALIS; PHYTOTHERAPY; PICRATES; PLANT COMPONENTS, AERIAL; PLANT EXTRACTS; SECOSTEROIDS; THIOBARBITURIC ACID REACTIVE SUBSTANCES;

CANDIDA; FUNGI; NEGIBACTERIA; PHYSALIS; PHYSALIS ALKEKENGI; POSIBACTERIA; SOLANACEAE;

EID: 76149143421     PISSN: 13880209     EISSN: 17445116     Source Type: Journal    
DOI: 10.3109/13880200903062606     Document Type: Article

References (43)

1. Ahmad S, Malik A, Yasmin R, Ulah N, Gul W, Khan PM, Nawaz HR, Afza N (1999): Withanolides from Physalis peruviana. Phytochemistry 50: 647-651.
2. Andrews JM (2001): BSAC standardized disc susceptibility testing method. J Antimicrob Chemother 48: 43-57.
3. Basey K, McGaw BA, Woolley JG (1992): Phygrine, an alkaloid from Physalis species. Phytochemistry 31: 4173-4176.
4. Bastos GNT, Santos ARS, Ferreira VMM, Costa AMR, Bispo CI, Silveira AJA, Do Nascimento JLM (2006): Antinociceptive effect of the aqueous extract obtained from roots of Physalis angulata L. on mice. J Ethnopharmacol 103: 241-245.
5. Baytop A (1978): Physalis L. In: Davis PH, ed., Flora of Turkey and the East Aegean Islands, Vol.6. Edinburgh, The Edinburgh University Press, pp. 444.
6. Baytop T (1999): Therapy with Medicinal Plants in Turkey (Past and Present). Istanbul, Nobel Medical Publishers, pp. 216.
7. Borenfreund E, Puerner, JA (1984): A simple quantitative procedure using monolayer cultures for cytotoxicity assays. J Tissue Cult Methods 9: 7-9.
8. Caceres A, Alvarez AV, Ovando AE, Samayoa BE (1991): Plants used in Guatemala for the treatment of respiratory diseases. 1. Screening of 68 plants against gram-positive bacteria. J Ethnopharmacol 31: 193-208.
9. Caceres A, Menendez H, Mendez E, Cohobon E, Samayoa BE, Jauregui E, Peralta E, Carrillo G (1995): Antigonorrheal activity of plants used in Guatemala for the treatment of sexually transmitted diseases. J Etnopharmacol 48: 85-88.
10. Castro DP, Figueiredo MB, Ribeiro IM, Tomassini TCB, Azambuja P, Garcia ES (2008): Immune depression in Rhodnius prolixus by secosteroids, physalins. J Insect Physiol 54: 552-562.
11. Chiang HC, Jaw SM, Chen CF, Kan WS (1992a): Antitumor agent, Physalin F from Physalis angulata L. Anticancer Res 12: 837-844.
12. Chiang HC, Jaw SM, Chen PM (1992b): Inhibitory effects of physalin B and physalin F on various human leukemia cells in vitro. Anticancer Res 12: 1155-1162.
13. Choudhary MI, Yousaf S, Ahmed S, Yasmeen K, Rahman A (2005): Antileishmanial physalins from Physalis minima. Chem Biodivers 2: 1164-1173.
14. Clinical Laboratory Standards Institute (2008): Performance Standards for Antimicrobial Susceptibility Testing; Ninth Informational Supplement. NCCLS document M100-S9. Wayne, PA, NCCLS.
15. Damu AG, Kuo PC, Su CR, Kuo TH, Chen TH, Bastow KF, Lee KH, Wu TS (2007): Isolation, structures, and structure-cytotoxic activity relationships of withanolides and physalins from Physalis angulata. J Nat Prod 70: 1146-1152.
16. Dinan LN, Sarker SD, Sik V (1997): 28-Hydroxywithanolide E from Physalis peruviana. Phytochemistry 44: 509-512.
17. Dos Santos JAA, Tomassini TCB, Xavier DCD, Ribeiro IM, Da Silva MTG, De Morais Filho ZB (2003): Molluscusidal activity of Physalis angulata L. extracts and fractions on Biomphalaria tenagophila under laboratory conditions. Mem Inst Oswaldo Cruz 98: 425-428.
18. Güvenç A, Houghton PJ, Duman H, Coşkun M, Şahin P (2005): Antioxidant activity studies on selected Sideritis species native to Turkey. Pharm Biol 43: 173-177.
19. Halliwell B, Chirico S (1993): Lipid peroxidation: its mechanism, measurement, and significance. Am J Clin Nutr 57: 715-725.
20. He QP, Ma L, Luo JY, He FY, Lou LG, Hu LH (2007): Cytotoxic withanolides from Physalis angulata L. Chem Biodivers 4: 443-449.
21. Hsieh WT, Huang KY, Lin HY, Chung JG (2006): Physalis angulata induced G2/M phase arrest in human breast cancer cells. Food Chem Toxicol 44: 974-983.
22. Januario AH, Rodrigues FE, Pietro RCLR, Kashima S, Sato DN, Franca SC (2002): Antimycobacterial Physalins from Physalis angulata L. Phytother Res 16: 445-448.
23. Kawai M, Matsuura T (1970): The structure of physalin C, a bitter principle of Physalis alkekengi var. francheti. Tetrahedron 26: 1743-1745.
24. Kawai M, Matsuura T, Kyuno S, Matsuki H, Takenaka M, Katsuoka T, Butsugan Y, Saito K (1987): A new physalin from Physalis alkekengi. Structure of physalin L. Phytochemistry 26: 3313-3317.
25. Kawai M, Ogura T, Makino B, Matsumoto A, Yamamura H, Butsugan Y, Hayashi M (1992): Physalins N and O from Physalis alkekengi. Phytochemistry 31: 4299-4302.
26. Kawai M, Makino B, Yamamuro H, Butsugan Y, Koji K, Hatsuo Y (1995): New physalins possessing an additional carbon-carbon bond from P. alkekengi var. francheti. Tetrahedron 51: 12529-12538.
27. Kawai M, Yamamoto T, Makino B, Yamamura H, Araki S, Butsugan Y, Saito K (2001): The structure of physalin T from Physalis alkekengi var. francheti. J Asian Nat Prod Res 3: 199-205.
28. Lee CC, Houghton P (2005): Cytotoxicity of plants from Malaysia and Thailand used traditionally to treat cancer. J Ethnopharmacol 100: 237-243.
29. Magalhaes HIF, Veras ML, Torres MR, Alves APNN, Pessoa ODL, Silveira ER, Costa-Lotufo LV, de Moraes MO, Pessoa C (2006): In-vitro and in-vivo antitumour activity of physalins B and D from Physalis angulata. J Pharm Pharmacol 58: 235-241.
30. Makino B, Kawai M, Iwata Y, Yamamuro H, Butsugan Y, Ogawa K, Hayahsi M (1995a): Physalins possessing an endoperoxy structure from Physalis alkekengi var. francheti. Structural revision of physalin K. Bull Chem Soc Jpn 68: 219-226.
31. Makino B, Kawai M, Ogura T, Nakanishi M, Yamamura H, Butsugan Y (1995b): Structural revision of physalin H isolated from Physalis angulata. J Nat Prod 58: 1668-1674.
32. Matsuura T, Kawai M, Nakashima R, Butsugan Y (1970): Structures of physalin A and physalin B, 13,14-seco-16,24-cyclosteroids from P. alkekengi var. francheti. J Chem Soc (C): 664-670.
33. Perez-Castorena AL, Garcia M, Martinez M, Maldonado E (2004): Physalins from Physalis solanaceus. Biochem Syst Ecol 32: 1231-1234.
34. Qiu L, Zhao F, Jiang ZH, Chen LX, Zhao Q, Lin HX, Yao XS, Qiu F (2008): Steroids and flavonoids from P. alkekengi var. francheti and their inhibitory effects on nitric oxide production. J Nat Prod 71: 642-646.
35. Ramadan MF, Morsel JT (2003): Oil goldenberry. J Agric Food Chem 51: 969-974.
36. Row LR, Sarma NS, Reddy KS, Matsuura T, Nakashima R (1978): The structures of physalins F and J from Physalis angulata and P. lancifolia. Phytochemistry 17: 1647-1650.
37. Row LR, Reddy KS, Sarma NS, Matsuura T, Nakashima R (1980): New physalins from Physalis angulata and Physalis lancifolia. Structure and reactions of physalins D, I, G and K. Phytochemistry 19: 1175-1181.
38. Shim JS, Kyung-Min P, Chung JY, Hwang JK (2002): Antibacterial activity of oleanolic acid from Physalis angulata against oral pathogens. Nutr Food 7: 215-218.
39. Silva MTG, Simas SM, Batista TGFM, Cardarelli P, Tomassini TCB (2005): Studies on antimicrobial activity, in vitro, of Physalis angulata L. (Solanaceae) fraction and physalin B bringing out the importance of assay determination. Mem Inst Oswaldo Cruz 100: 779-782.
40. Soares MBP, Bellintani MC, Riberio IM, Tomassino TCB, Riberio dos Santos R (2003): Inhibition of macrophage activation and lipopolysaccride induced death by seco-steroids purified from Physalis peruviana L. Eur J Pharmacol 459: 107-112.
41. Su BN, Misico R, Park EJ, Santarsiero BD, Mesecar AD, Fong HHS, Pezzuto JM, Kinghorn AD (2002): Isolation and characterization of bioactive principles of the leaves and stems of Physalis philadelphica. Tetrahedron 58: 3453-3466.
42. Vessal M, Mehrani HA, Omrani GH (1991): Effects of an aqueous extract of Physalis alkekengi fruit on estrus cycle, reproduction and uterine creatine kinase BB-isozyme in rats. J Ethnopharmacol 34: 69-78.
43. Wu SJ, Ng LT, Lin DL, Huang SN, Wang SS, Lin CC (2004): Physalis peruviana extract induces apoptosis in human HepG2 cells through CD95/CD95L system and the mitochondrial signaling transduction pathway. Cancer Lett 215: 199-208.