Polymorphism in the flanking regions of the PbGP43 gene from the human pathogen Paracoccidioides brasiliensis: Search for protein binding sequences and poly(A) cleavage sites

BMC Microbiology

Volumn 9, Issue , 2009, Pages

  Rocha, Antonio A ^a   Morais, Flvia V ^b   Puccia, Rosana ^a  

^a FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

^b INSTITUTO DE PESQUISA E DESENVOLVIMENTO   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOPROTEIN; GLYCOPROTEIN 43; OLIGONUCLEOTIDE; POLYADENYLIC ACID BINDING PROTEIN; SPACER DNA; UNCLASSIFIED DRUG; 43 KDA PROTEIN, PARACOCCIDIOIDES; FUNGAL DNA; FUNGAL PROTEIN; FUNGUS ANTIGEN; POLYADENYLIC ACID;

3' UNTRANSLATED REGION; AMINO ACID SEQUENCE; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DNA BINDING; DNA FLANKING REGION; DNA POLYMORPHISM; GEL MOBILITY SHIFT ASSAY; GENE MUTATION; GENETIC TRANSCRIPTION; MOLECULAR CLONING; NONHUMAN; PARACOCCIDIOIDES BRASILIENSIS; PHYLOGENY; POLYADENYLATION; POLYMERASE CHAIN REACTION; PROTEIN CLEAVAGE; TANDEM REPEAT; DNA SEQUENCE; GENETIC POLYMORPHISM; GENETICS; PARACOCCIDIOIDES; PROTEIN BINDING;

FUNGI; MURINAE; PARACOCCIDIOIDES BRASILIENSIS;

3' UNTRANSLATED REGIONS; ANTIGENS, FUNGAL; DNA, FUNGAL; FUNGAL PROTEINS; GLYCOPROTEINS; PARACOCCIDIOIDES; POLY A; POLYMORPHISM, GENETIC; PROTEIN BINDING; SEQUENCE ANALYSIS, DNA; TANDEM REPEAT SEQUENCES;

EID: 76149142807     PISSN: 14712180     EISSN: 14712180     Source Type: Journal    
DOI: 10.1186/1471-2180-9-277     Document Type: Article

References (38)

1. The habitat of Paracoccidioides brasiliensis: how far from solving the riddle? A Restrepo JG McEwen E Castaneda, Medical Mycology 2001 39 233 241 11446526
2. Towards a molecular genetic system for the pathogenic fungus Paracoccidioides brasiliensis. AJ Almeida JA Carmona C Cunha A Carvalho CA Rappleye WE Goldman, et al. Fungal Genet Biol 2007 44 1387 1398 10.1016/j.fgb.2007.04.004 17512227
3. Cryptic speciation and recombination in the fungus Paracoccidioides brasiliensis as revealed by gene genealogies. DR Matute JG McEwen R Puccia BA Montes G Blas San E Bagagli, et al. Mol Biol Evol 2006 23 65 73 10.1093/molbev/msj008 16151188
4. Exocellular components of Paracoccidioides brasiliensis: identification of a specific antigen. R Puccia S Schenkman PA Gorin LR Travassos, Infect Immun 1986 53 199 206 2424841
5. Attempts at a peptide vaccine against paracoccidioidomycosis, adjuvant to chemotherapy. LR Travassos EG Rodrigues LK Iwai CP Taborda, Mycopathologia 2008 165 341 352 10.1007/s11046-007-9056-1 18777638
6. 43-kilodalton glycoprotein from Paracoccidioides brasiliensis: immunochemical reactions with sera from patients with paracoccidioidomycosis, histoplasmosis, or Jorge Lobo's disease. R Puccia LR Travassos, J Clin Microbiol 1991 29 1610 1615 1722220
7. Serology of paracoccidioidomycosis. ZP Camargo, Mycopathologia 2008 165 289 302 10.1007/s11046-007-9060-5 18777635
8. The monoclonal antibody against the major diagnostic antigen of Paracoccidioides brasiliensis mediates immune protection in infected BALB/c mice challenged intratracheally with the fungus. R Buissa-Filho R Puccia AF Marques FA Pinto JE Munoz JD Nosanchuk, et al. Infect Immun 2008 76 3321 3328 10.1128/IAI.00349-08 18458072
9. Additive effect of P10 immunization and chemotherapy in anergic mice challenged intratracheally with virulent yeasts of Paracoccidioides brasiliensis. AF Marques MB da Silva MA Juliano JE Munhoz LR Travassos CP Taborda, Microbes Infect 2008 10 1251 1258 10.1016/j.micinf.2008.07.027 18694844
10. Monoclonal antibodies against the 43,000 Da glycoprotein from Paracoccidioides brasiliensis modulate laminin-mediated fungal adhesion to epithelial cells and pathogenesis. JL Gesztesi R Puccia LR Travassos AP Vicentini JZ de Moraes MF Franco, et al. Hybridoma 1996 15 415 422 10.1089/hyb.1996.15.415 8985752
11. Binding of extracellular matrix proteins to Paracoccidioides brasiliensis. MJ Mendes-Giannini PF Andreotti LR Vincenzi JL da Silva HL Lenzi G Benard, et al. Microbes Infect 2006 8 1550 1559 10.1016/j.micinf.2006.01.012 16698299
12. Cloning, characterization, and epitope expression of the major diagnostic antigen of Paracoccidioides brasiliensis. PS Cisalpino R Puccia LM Yamauchi MI Cano JF da Silveira LR Travassos, J Biol Chem 1996 271 4553 4560 10.1074/jbc.271.8.4553 8626811
13. Nucleocytoplasmic transport of proteins. AV Sorokin ER Kim LP Ovchinnikov, Biochemistry (Mosc) 2007 72 1439 1457 10.1134/S0006297907130032 18282135
14. Chromosomal polymorphism, syntenic relationships, and ploidy in the pathogenic fungus Paracoccidioides brasiliensis. LS Feitosa PS Cisalpino MR dos Santos RA Mortara TF Barros FV Morais, et al. Fungal Genet Biol 2003 39 60 69 10.1016/S1087-1845(03)00003-3 12742064
15. Polymorphism in the gene coding for the immunodominant antigen gp43 from the pathogenic fungus Paracoccidioides brasiliensis. FV Morais TF Barros MK Fukada PS Cisalpino R Puccia, J Clin Microbiol 2000 38 3960 3966 11060052
16. Virulence of Paracoccidioides brasiliensis and gp43 expression in isolates bearing known PbGP43 genotype. KC Carvalho L Ganiko WL Batista FV Morais ER Marques GH Goldman, et al. Microbes Infect 2005 7 55 65 10.1016/j.micinf.2004.09.008 15716071
17. Diversity in Paracoccidioides brasiliensis. The PbGP43 gene as a genetic marker. R Puccia JG McEwen PS Cisalpino, Mycopathologia 2008 165 275 287 10.1007/s11046-007-9055-2 18777634
18. Production of Paracoccidioides brasiliensis exoantigens for immunodiffusion tests. Z Camargo C Unterkircher SP Campoy LR Travassos, J Clin Microbiol 1988 26 2147 2151 3141460
19. Expression and isoforms of gp43 in different strains of Paracoccidioides brasiliensis. MC Moura-Campos JL Gesztesi AP Vincentini JD Lopes ZP Camargo, J Med Vet Mycol 1995 33 223 227 10.1080/02681219580000461 8531019
20. Secretion of the 43 kDa glycoprotein antigen by Paracoccidioides brasiliensis. BU Stambuk R Puccia ML de Almeida LR Travassos S Schenkman, J Med Vet Mycol 1988 26 367 373 10.1080/02681218880000521 3246625
21. Exocellular proteolytic activity of Paracoccidioides brasiliensis: cleavage of components associated with the basement membrane. R Puccia AK Carmona JL Gesztesi L Juliano LR Travassos, Med Mycol 1998 36 345 348 10075506
22. Transcription regulation of the Pbgp43 gene by nitrogen in the human pathogen Paracoccidioides brasiliensis. AA Rocha I Malavazi GH Goldman R Puccia, Fungal Genet Biol 2009 46 85 93 10.1016/j.fgb.2008.10.009 19013535
23. Identification of transcription elements in the 5' intergenic region shared by LON and MDJ1 heat shock genes from the human pathogen Paracoccidioides brasiliensis. Evaluation of gene expression. WL Batista TF Barros GH Goldman FV Morais R Puccia, Fungal Genet Biol 2007 44 347 356 10.1016/j.fgb.2006.11.002 17166750
24. The CreA repressor is the sole DNA-binding protein responsible for carbon catabolite repression of the alcA gene in Aspergillus nidulans via its binding to a couple of specific sites. C Panozzo E Cornillot B Felenbok, J Biol Chem 1998 273 6367 6372 10.1074/jbc.273.11.6367 9497366
25. Formation of mRNA 3' ends in eukaryotes: mechanism, regulation, and interrelationships with other steps in mRNA synthesis. J Zhao L Hyman C Moore, Microbiol Mol Biol Rev 1999 63 405 445 10357856
26. Biochemistry and molecular biology of exocellular fungal beta-(1,3)- and beta-(1,6)-glucanases. K Martin BM McDougall S McIlroy J Chen RJ Seviour, FEMS Microbiol Rev 2007 31 168 192 10.1111/j.1574-6976.2006.00055.x 17313520
27. Genetic regulation of nitrogen metabolism in the fungi. GA Marzluf, Microbiology and Molecular Biology Reviews 1997 61 17 32 9106362
28. Isolation and characterization of target sequences of the chicken Cdxa homeobox gene. Y Margalit S Yarus E Shapira Y Gruenbaum A Fainsod, Nucleic Acids Research 1993 21 4915 4922 10.1093/nar/21.21.4915 7909943
29. Performance assessment of promoter predictions on ENCODE regions in the EGASP experiment. VB Bajic MR Brent RH Brown A Frankish J Harrow U Ohler, et al. Genome Biology 2006 7 Suppl 1 3 10.1186/gb-2006-7-s1-s3 16925837
30. A role for CdxA in gut closure and intestinal epithelia differentiation. A Frumkin G Pillemer R Haffner N Tarcic Y Gruenbaum A Fainsod, Development 1994 120 253 263 7908627
31. A single p450 allele associated with insecticide resistance in Drosophila. PJ Daborn JL Yen MR Bogwitz G Le Goff E Feil S Jeffers, et al. Science 2002 297 2253 2256 10.1126/science.1074170 12351787
32. Endless forms: the evolution of gene regulation and morphological diversity. SB Carroll, Cell 2000 101 577 580 10.1016/S0092-8674(00)80868-5 10892643
33. New Paracoccidioides brasiliensis isolate reveals unexpected genomic variability in this human pathogen. LL Carrero G Nino-Vega MM Teixeira MJ Carvalho CM Soares M Pereira, et al. Fungal Genet Biol 2008 45 605 612 10.1016/j.fgb.2008.02.002 18364259
34. Phylogenetic analysis reveals a high level of speciation in the Paracoccidioides genus. MM Teixeira RC Theodoro MJ de Carvalho L Fernandes HC Paes RC Hahn, et al. Mol Phylogenet Evol 2009 52 273 283 10.1016/j.ympev.2009. 04.005 19376249
35. Protein factors in pre-mRNA 3'-end processing. CR Mandel Y Bai L Tong, Cell Mol Life Sci 2008 65 1099 1122 10.1007/s00018-007-7474-3 18158581
36. A large-scale analysis of mRNA polyadenylation of human and mouse genes. B Tian J Hu H Zhang CS Lutz, Nucleic Acids Res 2005 33 201 212 10.1093/nar/gki158 15647503
37. An AP1 element is involved in transcriptional regulation of Delta(9)-desaturase gene of Histoplasma capsulatum. A Tosco S Gargano GS Kobayashi B Maresca, Biochemical and Biophysical Research Communications 1997 230 457 461 10.1006/bbrc.1996.5984 9016802
38. Molecular identification of Paracoccidioides brasiliensis by 5' nuclease assay. CP Semighini ZP de Camargo R Puccia MH Goldman GH Goldman, Diagn Microbiol Infect Dis 2002 44 383 386 10.1016/S0732-8893(02)00472-8 12543545