Identification of transcription elements in the 5′ intergenic region shared by LON and MDJ1 heat shock genes from the human pathogen Paracoccidioides brasiliensis. Evaluation of gene expression

Fungal Genetics and Biology

Volumn 44, Issue 5, 2007, Pages 347-356

  Batista, Wagner L ^a   Barros, Tânia F ^b   Goldman, Gustavo H ^c   Morais, Flávia V ^d   Puccia, Rosana ^a  

^a FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

^b FEDERAL UNIVERSITY OF BAHIA   (Brazil)

^c UNIVERSITY OF SÃO PAULO   (Brazil)

^d INSTITUTO DE PESQUISA E DESENVOLVIMENTO   (Brazil)

Author keywords

Gene expression; Heat shock; LON; MDJ1; Oxidative stress; Paracoccidioides brasiliensis; Transcription elements

Indexed keywords

ENDOPEPTIDASE LA; HEAT SHOCK PROTEIN;

ARTICLE; GENE CONTROL; GENE EXPRESSION; GENE FUNCTION; GENE IDENTIFICATION; GENE LOCUS; GENETIC ANALYSIS; GENETIC POLYMORPHISM; GENETIC TRANSCRIPTION; MYCELIUM; NONHUMAN; NUCLEOTIDE SEQUENCE; PARACOCCIDIOIDES BRASILIENSIS; PATHOGENESIS; PRIORITY JOURNAL;

BASE SEQUENCE; BINDING SITES; DNA FOOTPRINTING; DNA, INTERGENIC; ELECTROPHORETIC MOBILITY SHIFT ASSAY; FUNGAL PROTEINS; GENE EXPRESSION REGULATION, FUNGAL; HEAT; HUMANS; MOLECULAR SEQUENCE DATA; OXIDATIVE STRESS; PARACOCCIDIOIDES; PARACOCCIDIOIDOMYCOSIS; PROTEIN BINDING; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TIME FACTORS; TRANSCRIPTION, GENETIC;

FUNGI; PARACOCCIDIOIDES BRASILIENSIS;

EID: 33947728073     PISSN: 10871845     EISSN: 10960937     Source Type: Journal    
DOI: 10.1016/j.fgb.2006.11.002     Document Type: Article

References (37)

1. Alarco A.M., and Raymond M. The bZip transcription factor Cap1p is involved in multidrug resistance and oxidative stress response in Candida albicans. J. Bacteriol. 181 (1999) 700-708
2. Amin J., Fernandez M., Ananthan J., Lis J.T., and Voellmy R. Cooperative binding of heat shock transcription factor to the Hsp70 promoter in vivo and in vitro. J. Biol. Chem. 269 (1994) 4804-4811
3. An J.H., and Blackwell T.K. SKN-1 links C. elegans mesendodermal specification to a conserved oxidative stress response. Genes Dev. 17 (2003) 1882-1893
4. Barros T.F., and Puccia R. Cloning and characterization of a LON gene homologue from the human pathogen Paracoccidioides brasiliensis. Yeast 18 (2001) 981-988
5. Batista W.L., Matsuo A.L., Ganiko L., Barros T.F., Veiga T.R., Freymuller E., and Puccia R. The PbMDJ1 gene belongs to a conserved MDJ1/LON locus in thermodimorphic pathogenic fungi and encodes a heat shock protein that localizes to both the mitochondria and cell wall of Paracoccidioides brasiliensis. Eukaryot. Cell 5 (2006) 379-390
6. Bota D.A., and Davies K.J. Lon protease preferentially degrades oxidized mitochondrial aconitase by an ATP-stimulated mechanism. Nat. Cell Biol. 4 (2002) 674-680
7. Bota D.A., Ngo J.K., and Davies K.J. Downregulation of the human Lon protease impairs mitochondrial structure and function and causes cell death. Free Radic. Biol. Med. 38 (2005) 665-677
8. Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72 (1976) 254
9. Campos E.G., Jesuino R.S., Dantas A.S., Brigido M.M., and Felipe M.S. Oxidative stress response in Paracoccidioides brasiliensis. Genet. Mol Res. 4 (2005) 409-429
10. Carvalho K.C., Ganiko L., Batista W.L., Morais F.V., Marques E.R., Goldman G.H., Franco M.F., and Puccia R. Virulence of Paracoccidioides brasiliensis and gp43 expression in isolates bearing known PbGP43 genotype. Microbes Infect. 7 (2005) 55-65
11. Crouy-Chanel A., Kohiyama M., and Richarme G. A novel function of Escherichia coli chaperone DnaJ. Protein-disulfide isomerase. J. Biol. Chem. 270 (1995) 22669-22672
12. Estruch F. Stress-controlled transcription factors, stress-induced genes and stress tolerance in budding yeast. FEMS Microbiol. Rev. 24 (2000) 469-486
13. Felipe M.S., Andrade R.V., Arraes F.B., Nicola A.M., Maranhao A.Q., Torres F.A., Silva-Pereira I., Pocas-Fonseca M.J., Campos E.G., Moraes L.M., Andrade P.A., Tavares A.H., Silva S.S., Kyaw C.M., Souza D.P., Network P., Pereira M., Jesuino R.S., Andrade E.V., Parente J.A., Oliveira G.S., Barbosa M.S., Martins N.F., Fachin A.L., Cardoso R.S., Passos G.A., Almeida N.F., Walter M.E., Soares C.M., Carvalho M.J., and Brigido M.M. Transcriptional profiles of the human pathogenic fungus Paracoccidioides brasiliensis in mycelium and yeast cells. J. Biol. Chem. 280 (2005) 24706-24714
14. Goldman G.H., dosReis M.E., Duarte R., Souza Bernardes L.A., Quiapin A.C., Vitorelli P.M., Savoldi M., Semighini C.P., de Oliveira R.C., Nunes L.R., Travassos L.R., Puccia R., Batista W.L., Ferreira L.E., Moreira J.C., Bogossian A.P., Tekaia F., Nobrega M.P., Nobrega F.G., and Goldman M.H. Expressed sequence tag analysis of the human pathogen Paracoccidioides brasiliensis yeast phase: identification of putative homologues of Candida albicans virulence and pathogenicity genes. Eukaryot. Cell 2 (2003) 34-48
15. Gutman A., and Wasylyk B. The collagenase gene promoter contains a TPA and oncogene-responsive unit encompassing the PEA3 and AP-1 binding sites. EMBO J. 9 (1990) 2241-2246
16. Hahn J.S., Hu Z., Thiele D.J., and Iyer V.R. Genome-wide analysis of the biology of stress responses through heat shock transcription factor. Mol. Cell. Biol. 24 (2004) 5249-5256
17. Kiang J.G., and Tsokos G.C. Heat shock protein 70 kDa: molecular biology, biochemistry, and physiology. Pharmacol. Ther. 80 (1998) 183-201
18. Leal C.V., Montes B.A., Mesa A.C., Rua A.L., Corredor M., Restrepo A., and McEwen J.G. Agrobacterium tumefaciens-mediated transformation of Paracoccidioides brasiliensis. Med. Mycol. 42 (2004) 391-395
19. Liu X.D., and Thiele D.J. Oxidative stress induced heat shock factor phosphorylation and HSF-dependent activation of yeast metallothionein gene transcription. Genes Dev. 10 (1996) 592-603
20. Marques E.R., Ferreira M.E., Drummond R.D., Felix J.M., Menossi M., Savoldi M., Travassos L.R., Puccia R., Batista W.L., Carvalho K.C., Goldman M.H., and Goldman G.H. Identification of genes preferentially expressed in the pathogenic yeast phase of Paracoccidioides brasiliensis, using suppression subtraction hybridization and differential macroarray analysis. Mol. Genet. Genom. 271 (2004) 667-677
21. Matute D.R., McEwen J.G., Puccia R., Montes B.A., San Blas G., Bagagli E., Rauscher J.T., Restrepo A., Morais F., Nino-Vega G., and Taylor J.W. Cryptic speciation and recombination in the fungus Paracoccidioides brasiliensis as revealed by gene genealogies. Mol. Biol. Evol. 23 (2006) 65-73
22. Morais F.V., Barros T.F., Fukada M.K., Cisalpino P.S., and Puccia R. Polymorphism in the gene coding for the immunodominant antigen gp43 from the pathogenic fungus Paracoccidioides brasiliensis. J. Clin. Microbiol. 38 (2000) 3960-3966
23. Nunes L.R., Costa d.O., Leite D.B., daSilva V.S., dos Reis M.E., Silva Ferreira M.E., Ribeiro D.C., Souza Bernardes L.A., Goldman M.H., Puccia R., Travassos L.R., Batista W.L., Nobrega M.P., Nobrega F.G., Yang D.Y., Braganca Pereira C.A., and Goldman G.H. Transcriptome analysis of Paracoccidioides brasiliensis cells undergoing mycelium-to-yeast transition. Eukaryot. Cell 4 (2005) 2115-2128
24. Puri N., Krishnamurthy S., Habib S., Hasnain S.E., Goswami S.K., and Prasad R. CDR1, a multidrug resistance gene from Candida albicans, contains multiple regulatory domains in its promoter and the distal AP-1 element mediates its induction by miconazole. FEMS Microbiol. Lett. 180 (1999) 213-219
25. Rooney P.J., and Klein B.S. Sequence elements necessary for transcriptional activation of BAD1 in the yeast phase of Blastomyces dermatitidis. Eukaryot. Cell 3 (2004) 785-794
26. Semighini C.P., de Camargo Z.P., Puccia R., Goldman M.H., and Goldman G.H. Molecular identification of Paracoccidioides brasiliensis by 5′ nuclease assay. Diagn. Microbiol. Infect. Dis. 44 (2002) 383-386
27. Silva M.B., Marques A.F., Nosanchuk J.D., Casadevall A., Travassos L.R., and Taborda C.P. Melanin in the dimorphic fungal pathogen Paracoccidioides brasiliensis: effects on phagocytosis, intracellular resistance and drug susceptibility. Microbes Infect. 8 (2006) 197-205
28. Soares R.B., Velho T.A., De Moraes L.M., Azevedo M.O., Soares C.M., and Felipe M.S. Hygromycin B-resistance phenotype acquired in Paracoccidioides brasiliensis via plasmid DNA integration. Med. Mycol. 43 (2005) 719-723
29. Srikantha T., Chandrasekhar A., and Soll D.R. Functional analysis of the promoter of the phase-specific WH11 gene of Candida albicans. Mol. Cell Biol. 15 (1995) 1797-1805
30. Stephen D.W., Rivers S.L., and Jamieson D.J. The role of the YAP1 and YAP2 genes in the regulation of the adaptive oxidative stress responses of Saccharomyces cerevisiae. Mol. Microbiol. 16 (1995) 415-423
31. Tachibana T., Astumi S., Shioda R., Ueno M., Uritani M., and Ushimaru T. A novel non-conventional heat shock element regulates expression of MDJ1 encoding a DnaJ homolog in Saccharomyces cerevisiae. J. Biol. Chem. 277 (2002) 22140-22146
32. Tosco A., Gargano S., Kobayashi G.S., and Maresca B. An AP1 element is involved in transcriptional regulation of delta9- desaturase gene of Histoplasma capsulatum. Biochem. Biophys. Res. Commun. 230 (1997) 457-461
33. Travassos L.R., Taborda C.P., Iwai L.K., Cunha-Neto E., and Puccia R. The gp43 from Paracoccidioides brasiliensis: a major diagnostic antigen and vaccine candidate. In: Domer J.E., and Kobayashi G.S. (Eds). Mycota XII, Human Fungal Pathogens (2004), Springer-Verlag, Berlin-Heidelberg 279-296
34. Urban C., Xiong X., Sohn K., Schroppel K., Brunner H., and Rupp S. The moonlighting protein Tsa1p is implicated in oxidative stress response and in cell wall biogenesis in Candida albicans. Mol. Microbiol. 57 (2005) 1318-1341
35. van Dyck L., and Langer T. ATP-dependent proteases controlling mitochondrial function in the yeast Saccharomyces cerevisiae. Cell Mol. Life Sci. 56 (1999) 825-842
36. Voos W., and Rottgers K. Molecular chaperones as essential mediators of mitochondrial biogenesis. Biochim. Biophys. Acta 1592 (2002) 51-62
37. Yamamoto A., Mizukami Y., and Sakurai H. Identification of a novel class of target genes and a novel type of binding sequence of heat shock transcription factor in Saccharomyces cerevisiae. J. Biol. Chem. 280 (2005) 11911-11919