Certolizumab pegol: A TNF-α antagonist for the treatment of moderate-to-severe Crohn's disease

Annals of Pharmacotherapy

Volumn 44, Issue 2, 2010, Pages 333-342

  Smith, Lisa S ^a   Nelson, Michael ^b   Dolder, Christian R ^a  

^a WINGATE UNIVERSITY   (United States)

^b REGIS UNIVERSITY   (United States)

Author keywords

Certolizumab pegol; Crohn's disease; Inflammatory bowel disease; TNF antagonist

Indexed keywords

ADALIMUMAB; ANTINUCLEAR ANTIBODY; AUTOANTIBODY; C REACTIVE PROTEIN; CERTOLIZUMAB PEGOL; CYTOCHROME P450; ETANERCEPT; IMMUNOGLOBULIN G ANTIBODY; INFLIXIMAB; INTERLEUKIN 1; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; LIVE VACCINE; PEPTIDASE; PLACEBO; PROTEINASE; RECOMBINANT INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; TUMOR NECROSIS FACTOR ALPHA;

ABDOMINAL PAIN; ANTIBODY DEPENDENT CELLULAR CYTOTOXICITY; ANTIBODY PRODUCTION; ANTIGEN BINDING; APOPTOSIS; AREA UNDER THE CURVE; ARTHRALGIA; BACKACHE; CLINICAL ASSESSMENT; CLINICAL TRIAL; COCCIDIOIDOMYCOSIS; COMPLEMENT DEPENDENT CYTOTOXICITY; CROHN DISEASE; CYTOKINE PRODUCTION; DISEASE EXACERBATION; DRUG ACCUMULATION; DRUG BINDING; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG CONTRAINDICATION; DRUG COST; DRUG DISTRIBUTION; DRUG EFFICACY; DRUG ELIMINATION; DRUG HALF LIFE; DRUG INFORMATION; DRUG LABELING; DRUG MANUFACTURE; DRUG MECHANISM; DRUG PROTEIN BINDING; DRUG SAFETY; DRUG SOLUBILITY; DRUG STRUCTURE; EVIDENCE BASED MEDICINE; FEVER; GASTROINTESTINAL SURGERY; GASTROINTESTINAL TRACT; GERIATRICS; HEADACHE; HEALTH CARE COST; HISTOPLASMOSIS; HUMAN; IMMUNOREACTIVITY; IMMUNOREGULATION; INFECTION; INFECTION RISK; INFORMATION RETRIEVAL; INJECTION SITE REACTION; LYMPHOMA; MAXIMUM PLASMA CONCENTRATION; MEDLINE; MYCOSIS; NAUSEA; OBSERVATIONAL STUDY; OPPORTUNISTIC INFECTION; OUTCOME ASSESSMENT; PATHOPHYSIOLOGY; PATIENT COUNSELING; PEDIATRICS; PNEUMONIA; POSTMARKETING SURVEILLANCE; PRESCRIPTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PYELONEPHRITIS; RECOMMENDED DRUG DOSE; REMISSION; REVIEW; RHINOPHARYNGITIS; TREATMENT RESPONSE; TUBERCULOSIS; UPPER RESPIRATORY TRACT INFECTION; URINARY EXCRETION; URINARY TRACT INFECTION; VOMITING;

ADULT; ANTI-INFLAMMATORY AGENTS; CROHN DISEASE; HUMANS; IMMUNOGLOBULIN FAB FRAGMENTS; POLYETHYLENE GLYCOLS; RANDOMIZED CONTROLLED TRIALS AS TOPIC; SEVERITY OF ILLNESS INDEX; TUMOR NECROSIS FACTOR-ALPHA;

EID: 76149138475     PISSN: 10600280     EISSN: None     Source Type: Journal    
DOI: 10.1345/aph.1M314     Document Type: Review

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