Instrumented one and two level posterolateral fusions with recombinant human bone morphogenetic protein-2 and allograft: A computed tomography study

Spine

Volumn 35, Issue 1, 2010, Pages 124-129

  Stambough, Jeffery L ^a   Clouse, Elisha K ^b   Stambough, Jeffrey B ^c  

^a 705 Engineering Research Center   (United States)

^b UNIVERSITY OF CINCINNATI   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Allograft (freeze dried); Arthrodesis; Bone morphogenetic protein type II; Lumbar spinal fusion

Indexed keywords

COLLAGEN SPONGE; RECOMBINANT BONE MORPHOGENETIC PROTEIN 2;

ADULT; AGED; ARTHRODESIS; ARTICLE; BACKACHE; BONE ALLOGRAFT; CLINICAL ARTICLE; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; FEMALE; FOLLOW UP; HUMAN; IMAGE RECONSTRUCTION; INTERVERTEBRAL DISK DEGENERATION; LEG PAIN; LUMBAR SPINE; MALE; OUTCOME ASSESSMENT; PAIN ASSESSMENT; POSTOPERATIVE COMPLICATION; PRIORITY JOURNAL; RATING SCALE; SHORT FORM 36; SPINE FUSION; SPINE RADIOGRAPHY; SURGICAL TECHNIQUE; VERTEBRAL CANAL STENOSIS;

ADULT; AGED; AGED, 80 AND OVER; BONE MORPHOGENETIC PROTEINS; BONE TRANSPLANTATION; FEMALE; HUMANS; INTERVERTEBRAL DISK DEGENERATION; LUMBAR VERTEBRAE; MALE; MIDDLE AGED; PROSPECTIVE STUDIES; RECOMBINANT PROTEINS; SEVERITY OF ILLNESS INDEX; SPINAL FUSION; SPINAL STENOSIS; TRANSFORMING GROWTH FACTOR BETA; TREATMENT OUTCOME;

EID: 76149107495     PISSN: 03622436     EISSN: 15281159     Source Type: Journal    
DOI: 10.1097/BRS.0b013e3181c46c3a     Document Type: Article

References (18)

1. Zdeblick TA, Hanley EN Jr, Sonntag VK, et al. Indications for lumbar spinal fusion. Introduction: 1995 focus issue meeting on fusion. Spine 1995; 20(suppl 24):124S-5S.
2. Zdeblick TA. A prospective, randomized study of lumbar fusion. Preliminary results. Spine 1993;18:983-991
3. Kanayama M, Cunningham BW, Sefter JC, et al. Does spinal instrumentation influence the healing process of posterolateral spinal fusion? An in vivo animal model. Spine 1999;24:1058-1065
4. Kanayama M, Cunningham BW, Weis JC, et al. Maturation of the posterolateral spinal fusion and its effect on load-sharing of spinal instrumentation. An in vivo sheep model. J Bone Joint Surg Am 1997;29:1710-1720
5. Boden SD, Kang J, Sandhu H, et al. Use of recombinant human bone morphogenetic protein-2 to achieve posterolateral lumbar spine fusion in humans: a prospective, randomized clinical pilot trial: 2002 Volvo award in clinical studies. Spine 2002;27:2662-2673
6. Vaccaro AR, Anderson DG, Patel T, et al. Comparison of OP-1 Putty (rhBMP-7) to iliac crest autograft for posterolateral lumbar arthrodesis: a minimum 2-year follow-up pilot study. Spine 2005;30:2709-2716 (Pubitemid 43011029)
7. Vaccaro AR, Chiba K, Heller JG, et al; North American Spine Society for Contemporary Concepts in Spine Care. Bone grafting alternatives in spinal surgery. Spine J 2002;2:205-215
8. Gibson S, McLeod I, Wardlaw D, et al. Allograft versus autograft in instrumented posterolateral lumbar spinal fusion: a randomized control trial. Spine 2002;27:1599-1603
9. Jones KC, Andrish J, Kuivila T, et al. Radiographic outcomes using freezedried cancellous allograft bone for posterior spinal fusion in pediatric idiopathic scoliosis. J Pediatr Orthop 2002;22:285-289
10. Boden SD. The ABC's of BMP's. Orthop Nurs 2005;24:49-52.
11. Bridwell KH, Anderson PA, Boden SD, et al. What's new in spine surgery. J Bone Joint Surg Am 2005;87:1892-1901
12. Sandhu HS. Bone morphogenetic proteins and spinal surgery. Spine 2003; 28(suppl 15):S64 -73.
13. Urist MR. Bone: formation by autoinduction, 1965. Clin Orthop Relat Res 2002:4-10.
14. Urist MR, Sato K, Brownell, et al. Human bone morphogenetic protein (hBMP). Proc Soc Exp Biol Med 1983;173:194-199
15. Lietman SA, Inoue N, Rafiee B, et al. The effect of recombinant human osteogenic protein-1 on allograft incorporation. J Bone Joint Surg Br 2005; 87:1292-1297
16. Vaccaro AR, Patel T, Fischgrund J, et al. A pilot study evaluating safety and efficacy of OP-1 Putty (rhBMP-7) as a replacement for iliac crest autograft in a posterolateral lumbar arthrodesis for degenerative spondylolisthesis. Spine 2004;29:1885-1892.
17. Ahlmann E, Patzakis M, Roidis N, et al. Comparison of anterior and posterior iliac crest bone grafts in terms of harvest-site morbidity and functional outcomes. J Bone Joint Surg Am 2002;84-A:716-720
18. Glassman SD, Carreon LY, Djurasovic M, et al. Lumbar fusion outcomes stratified by specific diagnostic indication. Spine J 2009;9: 13-21.