Controlled radio-frequency hyperthermia using an MR scanner and simultaneous monitoring of temperature and therapy response by 1H, 23Na and 31P magnetic resonance spectroscopy in subcutaneously implanted 9L-gliosarcoma

International Journal of Hyperthermia

Volumn 26, Issue 1, 2010, Pages 79-90

  James, Judy R ^a,b   Gao, Yong ^a   Soon, Victor C ^a   Topper, Stephen M ^a   Babsky, Andriy ^a   Bansal, Navin ^a,b  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b PURDUE UNIVERSITY   (United States)

Author keywords

Cellular energy; MRI; PH; RF hyperthermia; Sodium

Indexed keywords

1,4,7,10 TETRAAZACYCLODODECANE 1,4,7,10 TETRAACETIC ACID; SODIUM; THULIUM;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOENERGY; BODY TEMPERATURE MONITORING; CANCER CELL CULTURE; GLIOSARCOMA; HYPERTHERMIC THERAPY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SCANNER; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PH MEASUREMENT; PHOSPHORUS NUCLEAR MAGNETIC RESONANCE; PROTON NUCLEAR MAGNETIC RESONANCE; RADIOFREQUENCY; RAT; SODIUM NUCLEAR MAGNETIC RESONANCE; TREATMENT RESPONSE;

ANIMALS; BODY TEMPERATURE; GLIOSARCOMA; HYPERTHERMIA, INDUCED; MAGNETIC RESONANCE SPECTROSCOPY; MALE; NEOPLASM TRANSPLANTATION; ORGANOMETALLIC COMPOUNDS; PHOSPHORUS; RADIO WAVES; RATS; RATS, INBRED F344; SODIUM;

EID: 76149097879     PISSN: 02656736     EISSN: 14645157     Source Type: Journal    
DOI: 10.3109/02656730903373509     Document Type: Article

References (38)

1. Pennacchioli E, Fiore M, Gronchi A. Hyperthermia as an adjunctive treatment for soft-tissue sarcoma. Expert Rev Anticancer Ther 2009;9:199-210.
2. Hildebrandt B, Wust P. The biologic rationale of hyperthermia. Cancer Treat Res 2007;134:171-184.
3. Falk MH, Issels RD. Hyperthermia in oncology. Int J Hyperthermia 2001;17:1-18.
4. Perez CA, Gillespie B, Pajak T, Hornback NB, Enami B, Rubin P. Quality assurance problems in clinical hyperthermia and their impact on therapeutic outcome: A report by the Radiation Therapy Oncology Group. Int J Radiat Oncol Biol Phys 1989;16:551-558.
5. Bezabeh T, Evelhoch JL, Sloop DJ, Ackerman JJ. Methodology for applied 4MHz RF hyperthermia concomitant with 31P NMR spectroscopic monitoring of murine tumours. Int J Hyperthermia 2004;20:637-645.
6. Jayasundar R, Hall LD, Bleehen NM. RF coils for combined MR and hyperthermia studies: II. MR coil as a hyperthermic applicator. Magn Reson Imaging 2001;19:117-122. (Pubitemid 32274123)
7. Sreenivasa G, Gellermann J, Rau B, Nadobny J, Schlag P, Deuflhard P, Felix R, Wust P. Clinical use of the hyperthermia treatment planning system HyperPlan to predict effectiveness and toxicity. Int J Radiat Oncol Biol Phys 2003;55:407-419.
8. Babsky A, Hekmatyar SK, Wehrli S, Nelson D, Bansal N. Effects of temperature on intracellular sodium, pH and cellular energy status in RIF-1 tumor cells. NMR Biomed 2004;17:33-42.
9. Babsky A, Hekmatyar SK, Wehrli S, Nelson D, Bansal N. Hyperthermia-induced changes in intracellular sodium, pH and bioenergetic status in perfused RIF-1 tumor cells determined by 23Na and 31P magnetic resonance spectroscopy. Int J Hyperthermia 2005;21:141-158.
10. Mikkelsen RB, Asher CR. Effects of hyperthermia on the membrane potential and Nap transport of V79 fibroblasts. J Cell Physiol 1990;144:216-221.
11. Skrandies S, Bremer B, Pilatus U, Mayer A, Neuhaus-Steinmetz U, Rensing L. Heat shock-and ethanol-induced ionic changes in C6 rat glioma cells determined by NMR and fluorescence spectroscopy. Brain Res 1997;746:220-230.
12. Ng TC, Evanochko WT, Hiramoto RN, Ghanta VK, Lilly MB, Lawson AJ, Corbett TH, Durant JR, Glickson JD. 31P NMR spectroscopy of in vivo tumors. J Magn Reson 1982; 49:271-286.
13. Naruse S, Higuchi T, Horikawa Y, Tanaka C, Nakamura K, Hirakawa K. Radiofrequency hyperthermia with successive monitoring of its effects on tumors using NMR spectroscopy. Proc Nat Acad Sci USA 1986;83:8343-8347.
14. Jayasundar R, Honess D, Hall LD, Bleehen NM. Simultaneous evaluation of the effects of RF hyperthermia on the intra-and extracellular tumor pH. Magn Reson Med 2000;43:1-8.
15. Bezabeh T, Evelhoch JL, Thompson P, Sloop DJ, Ackerman JJ. Therapeutic efficacy as predicted by quantitative assessment of murine RIF-1 tumour pH and phosphorous metabolite response during hyperthermia: An in vivo 31P NMR study. Int J Hyperthermia 2004;20:335-357.
16. Hekmatyar SK, Poptani H, Babsky A, Leeper DB, Bansal N. Non-invasive magnetic resonance thermometry using thulium-1,4,7,10-tetraazacyclododecane-1,4, 7,10-tetraacetate (TmDOTA-). Int J Hyperthermia 2002;18:165-179.
17. Hekmatyar SK, Kerkhoff RM, Pakin SK, Hopewell P, Bansal N. Noninvasive thermometry using hyperfine-shifted MR signals from paramagnetic lanthanide complexes. Int J Hyperthermia 2005;21:561-574.
18. Zuo CS, Mahmood A, Sherry AD. TmDOTA: A sensitive probe for MR thermometry in vivo. J Magn Reson 2001; 151:101-106.
19. Haase A, Frahm J, Hanicke W, Matthaei D. 1H NMR chemical shift selective (CHESS) imaging. Phys Med Biol 1985;30:341-344.
20. Winter PM, Bansal N. Triple-quantum-filtered 23Na NMR spectroscopy of subcutaneously implanted 9L gliosarcoma in the rat in the presence of TmDOTP5. J Magn Reson 2001;152:70-78.
21. Gillies RJ, Liu Z, Bhujwalla Z. 31P-MRS measurements of extracellular pH of tumors using 3-aminopropylphosphonate. Am J Physiol 1994;267:C195-203.
22. Sapareto SA, Dewey WC. Thermal dose determination in cancer therapy. Int J Radiat Oncol Biol Phys 1984; 10:787-800.
23. Kost GJ. pH standardization for phosphorus-31 magnetic resonance heart spectroscopy at different temperatures. Magn Reson Med 1990;14:496-506.
24. Stubbs M, Rodrigues L, Howe FA, Wang J, Jeong KS, Veech RL, Griffiths JR. Metabolic consequences of a reversed pH gradient in rat tumors. Cancer Res 1994;54:4011-4016.
25. ICNIRP 1998 Guidelines for limiting exposure to timevarying electric, magnetic and electromagnetic fields (up to 300 GHz). Health Physics 74;4:494-522.
26. Ettinger KV. Radiofrequency power sources for hyperthermia. In: Field SB, Franconi C, editors. Physics and Technology of Hyperthermia: Dordrecht. M. Nijhoff Publishers, 1987. pp 250-293.
27. Stratton JA. Electromagnetic Theory. York, PA: McGraw-Hill Book Company; 1941.
28. Winter PM, Bansal N. TmDOTP5-as a 23Na shift reagent for the subcutaneously implanted 9L gliosarcoma in rats. Magn Reson Med 2001;45:436-442.
29. Goldsmith M, Damadian R. NMR in cancer. VII. Sodium-23 magnetic resonance of normal and cancerous tissues. Physiol Chem Phys 1975;7:263-269.
30. Damadian R, Cope FW. NMR in cancer. V. Electronic diagnosis of cancer by potassium (39K) nuclear magnetic resonance: Spin signatures and T1 beat patterns. Physiol Chem Phys 1974;6:309-322.
31. De Poorter J, De Wagter C, De Deene Y, et al. Noninvasive MRI thermometry with the proton resonance frequency (PRF) method: In vivo results in human muscle. Magn Reson Med 1995;33:74-81.
32. James JR, Gao Y, Miller MA, Babsky A, Bansal N. Absolute temperature MR imaging with thulium 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetramethyl-1,4,7, 10-tetraacetic acid (TmDOTMA(-)). Magn Reson Med 2009;12:12.
33. Hofer KG, Mivechi NF. Tumor cell sensitivity to hyperthermia as a function of extracellular and intracellular pH. J Natl Cancer Inst 1980;65:621-625.
34. Song CW. Effect of local hyperthermia on blood flow and microenvironment: A review. Cancer Res 1984;44: 4721s-4730s.
35. Anderson RL, Hahn GM. Differential effects of hyperthermia on the Nap,Kp-ATPase of Chinese hamster ovary cells. Radiat Res 1985;102:314-323.
36. Ruifrok A, Kanon B, Konings A. Nap/Kp ATPase activity in mouse lung fibroblasts and HeLa S3 cells during and after hyperthermia. Int J Hyperthermia 1986;2:51-59.
37. Lilly MB, Katholi CR, Ng TC. Direct relationship between high-energy phosphate content and blood flow in thermally treated murine tumors. J Natl Cancer Inst 1985;75:885-889.
38. Boyer M, Tannock I. Regulation of intracellular pH in tumor cell lines: Influence of microenvironmental conditions. Cancer Res 1992;52:4441-4447.