3D-QSAR study of c-Src kinase inhibitors based on docking

Journal of Molecular Modeling

Volumn 16, Issue 2, 2010, Pages 361-375

  Cao, Ran ^a   Mi, Na ^a   Zhang, Huabei ^a  

^a BEIJING NORMAL UNIVERSITY   (China)

Author keywords

3D QSAR; C Src kinase inhibitor; CoMFA; CoMSIA; Docking

Indexed keywords

ANILINOQUINAZOLINE DERIVATIVE; N (5 CHLORO 1,3 BENZODIOXOL 4 YL) 7 [2 (4 METHYL 1 PIPERAZINYL)ETHOXY] 5 (TETRAHYDRO 2H PYRAN 4 YLOXY) 4 QUINAZOLINAMINE; PROTEIN TYROSINE KINASE INHIBITOR; QUINOLINE CARBONITRILE DERIVATIVE; UNCLASSIFIED DRUG;

ALLOSTERISM; ARTICLE; COMPARATIVE MOLECULAR FIELD ANALYSIS; COMPARATIVE MOLECULAR SIMILARITY INDICES ANALYSIS; CONTROLLED STUDY; CRYSTAL STRUCTURE; DRUG DESIGN; MOLECULAR DOCKING; PREDICTION; PRIORITY JOURNAL; QUANTITATIVE STRUCTURE ACTIVITY RELATION; SIMULATION;

ANTINEOPLASTIC AGENTS; COMPUTER SIMULATION; HUMANS; NITRILES; PROTEIN BINDING; PROTEIN KINASE INHIBITORS; PROTEIN-TYROSINE KINASES; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; QUINAZOLINES; QUINOLINES;

EID: 75949090367     PISSN: 16102940     EISSN: 09485023     Source Type: Journal    
DOI: 10.1007/s00894-009-0530-1     Document Type: Article

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