Synthesis and investigation of inhibition effect of fluorinated sulfonamide derivatives on carbonic anhydrase

European Journal of Medicinal Chemistry

Volumn 45, Issue 3, 2010, Pages 1225-1229

  Benfodda, Zohra ^a   Guillen, Franck ^b   Romestand, Bernard ^c   Dahmani, Abdelkader ^a   Blancou, Hubert ^a  

^a UNIVERSITÉ DE MONTPELLIER   (France)

^b UNIV MONTPELLIER   (France)

^c INSTITUT DES SCIENCES DE L EVOLUTION   (France)

Author keywords

Carbonic anhydrase; Cellular toxicity; Perfluoroalkanesulfonamides; Sodium salt of perfluoroalkanesulfonamides

Indexed keywords

1,1,2,2,3,3,4,4 OCTAFLUORO N BUTANE 1 4 BISSULFONAMIDE; 1,1,2,2,3,3,4,4,5,5,6,6,6 TRIDECAFLUORO N HEXANE 1 SULFONAMIDE; 1,1,2,2,3,3,4,4,5,5,6,6,7,7,7 PENTADECAFLUORO N HEPTANE 1 SULFONAMIDE; 3,3,4,4,5,5,6,6,6 NONAFLUORO N HEXANESULFONAMIDE; 3,3,4,4,5,5,6,6,7,7,8,8,8 TRIDECAFLUORO N OCTANESULFONAMIDE; 3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10 HEPTADECAFLUORO N DECANESULFONAMIDE; ACETAZOLAMIDE; CARBONATE DEHYDRATASE; CARBONATE DEHYDRATASE II; N HEXANESULFONAMIDE; N OCTANESULFONAMIDE; PERFLUOROBUTANESULFONAMIDE; PERFLUOROOCTANESULFONAMIDE; SODIUM PERFLUOROBUTANESULFONAMIDE; SODIUM PERFLUOROHEXANESULFONAMIDE; SODIUM PERFLUOROOCTANESULFONAMIDE; SULFONAMIDE; UNCLASSIFIED DRUG;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CONTROLLED STUDY; CYTOTOXICITY; DRUG SYNTHESIS; ENZYME INHIBITION; FLUORINATION; FLUORINE NUCLEAR MAGNETIC RESONANCE; HUMAN; IC 50; INFRARED SPECTROSCOPY; MASS SPECTROMETRY; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; SHEEP;

AMMONIA; ANIMALS; CARBONIC ANHYDRASE II; CARBONIC ANHYDRASE INHIBITORS; CARBONIC ANHYDRASES; CATTLE; ENZYME ACTIVATION; GASES; HUMANS; MOLECULAR STRUCTURE; SHEEP; SULFONAMIDES;

EID: 75849162556     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2009.11.052     Document Type: Article

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