Synthesis, cytotoxicity, antiviral activity and interferon inducing ability of 6-(2-aminoethyl)-6H-indolo[2,3-b]quinoxalines

European Journal of Medicinal Chemistry

Volumn 45, Issue 3, 2010, Pages 1237-1243

  Shibinskaya, Marina O ^a   Lyakhov, Sergey A ^a,b   Mazepa, Alexander V ^a   Andronati, Sergey A ^a,b   Turov, Alexander V ^c   Zholobak, Nadezhda M ^d   Spivak, Nikolay Ya ^d  

^a A V BOGATSKY PHYSICO CHEMICAL INSTITUTE   (Ukraine)

^b ODESSA NATIONAL UNIVERSITY   (Ukraine)

^c TARAS SHEVCHENKO NATIONAL UNIVERSITY OF KYIV   (Ukraine)

^d ZABOLOTNY INSTITUTE OF MICROBIOLOGY AND VIROLOGY   (Ukraine)

Author keywords

Antiviral activity; Indolo 2,3 b quinoxaline; Interferon; Synthesis

Indexed keywords

(2 INDOLO[2,3 B]QUINOXALIN 6 YL ETHYL)DIMETHYLAMINE; (2 INDOLO[2,3 B]QUINOXALIN 6 YL ETHYL)DIPROPYLAMINE; 6 (2 AZEPAN 1 YL ETHYL) 6H INDOLO[2,3 B]QUINOXALINE; 6 (2 MORPHOLIN 4 YL ETHYL) 6H INDOLO[2,3 B]QUINOXALINE; 6 (2 PIPERIDIN 1 YL ETHYL) 6H INDOLO[2,3 B]QUINOXALINE; 6 (2 PYRROLIDIN 1 YL ETHYL) 6H INDOLO[2,3 B]QUINOXALINE; 6 [2 (2 METHYLPIPERIDIN 1 YL)ETHYL] 6H INDOLO[2,3 B]QUINOXALINE; 6 [2 (4 METHYLPIPERAZIN 1 YL) ETHYL] 6H INDOLO[2,3 B]QUINOXALINE; 6 [2 (4 METHYLPIPERIDIN 1 YL) ETHYL] 6H INDOLO[2,3 B]QUINOXALINE; ANTIVIRUS AGENT; BUTYL(2 INDOLO[2,3 B]QUINOXALIN 6 YL ETHYL)METHYLAMINE; BUTYLETHYL(2 INDOLO[2,3 B]QUINOXALIN 6 YL ETHYL)AMINE; DIETHYL(2 INDOLO[2,3 B]QUINOXALIN 6 YL ETHYL)AMINE; INTERFERON; MORPHOLINE; PIPERIDINE DERIVATIVE; QUINOXALINE DERIVATIVE; TILORONE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIVIRAL ACTIVITY; ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG CYTOTOXICITY; DRUG POTENCY; DRUG SYNTHESIS; FIBROBLAST; NONHUMAN; VESICULAR STOMATITIS VIRUS;

ANIMALS; ANTIVIRAL AGENTS; CELL LINE; FIBROBLASTS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; INDOLES; INHIBITORY CONCENTRATION 50; INTERFERONS; MICE; MOLECULAR STRUCTURE; QUINOXALINES; SWINE; VESICULOVIRUS;

EID: 75849133718     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2009.12.014     Document Type: Article

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