-
1
-
-
0000520727
-
Virus interference. I. Interferon
-
Isaacs A, Lindenmann J. Virus interference. I. Interferon. Proc R Soc Lond 1957; 147:258-67.
-
(1957)
Proc R Soc Lond
, vol.147
, pp. 258-267
-
-
Isaacs, A.1
Lindenmann, J.2
-
2
-
-
33748867387
-
Mechanism of action of interferon. I. Relationship with viral ribonucleic acid
-
De Somer P, Prinzie A, Denys P Jr, Schonne E. Mechanism of action of interferon. I. Relationship with viral ribonucleic acid. Virology 1962; 16:63-70.
-
(1962)
Virology
, vol.16
, pp. 63-70
-
-
De Somer, P.1
Prinzie, A.2
Denys Jr., P.3
Schonne, E.4
-
3
-
-
0014211628
-
Interferons of mice and men
-
Merigan TC. Interferons of mice and men. N Engl J Med 1967; 276:913-20.
-
(1967)
N Engl J Med
, vol.276
, pp. 913-920
-
-
Merigan, T.C.1
-
4
-
-
0014213806
-
Induction of circulating interferon by synthetic anionic polymers of known composition
-
Merigan TC. Induction of circulating interferon by synthetic anionic polymers of known composition. Nature 1967; 214:416-7.
-
(1967)
Nature
, vol.214
, pp. 416-417
-
-
Merigan, T.C.1
-
5
-
-
0014202956
-
Interferon induction in man by a synthetic polyanion of defined composition
-
Merigan TC, Regelson W. Interferon induction in man by a synthetic polyanion of defined composition. N Engl J Med 1967; 277:1283-7.
-
(1967)
N Engl J Med
, vol.277
, pp. 1283-1287
-
-
Merigan, T.C.1
Regelson, W.2
-
6
-
-
0014325578
-
Antiviral activity of polyacrylic and polymethacrylic acids. I. Mode of action in vitro
-
De Somer P, De Clercq E, Billiau A, Schonne E, Claesen M. Antiviral activity of polyacrylic and polymethacrylic acids. I. Mode of action in vitro. J Virol 1968; 2:878-85.
-
(1968)
J Virol
, vol.2
, pp. 878-885
-
-
De Somer, P.1
De Clercq, E.2
Billiau, A.3
Schonne, E.4
Claesen, M.5
-
7
-
-
0014325810
-
Antiviral activity of polyacrylic and polymethacrylic acids. II. Mode of action in vivo
-
De Somer P, De Clercq E, Billiau A, Schonne E, Claesen M. Antiviral activity of polyacrylic and polymethacrylic acids. II. Mode of action in vivo. J Virol 1968; 2:886-93.
-
(1968)
J Virol
, vol.2
, pp. 886-893
-
-
De Somer, P.1
De Clercq, E.2
Billiau, A.3
Schonne, E.4
Claesen, M.5
-
8
-
-
0014167279
-
Interferon's promise in clinical medicine: Fact or fancy?
-
Merigan TC. Interferon's promise in clinical medicine: fact or fancy? Am J Med 1967; 43:817-21.
-
(1967)
Am J Med
, vol.43
, pp. 817-821
-
-
Merigan, T.C.1
-
9
-
-
0014124597
-
Inducers of interferon and host resistance. II. Multistranded synthetic polynucleotide complexes
-
Field AK, Tytell AA, Lampson GP, Hilleman MR. Inducers of interferon and host resistance. II. Multistranded synthetic polynucleotide complexes. Proc Natl Acad Sci USA 1967; 58:1004-10.
-
(1967)
Proc Natl Acad Sci USA
, vol.58
, pp. 1004-1010
-
-
Field, A.K.1
Tytell, A.A.2
Lampson, G.P.3
Hilleman, M.R.4
-
10
-
-
0014686756
-
Requirement of a stable secondary structure for the antiviral activity of polynucleotides
-
De Clercq E, Merigan TC. Requirement of a stable secondary structure for the antiviral activity of polynucleotides. Nature 1969; 222:1148-52.
-
(1969)
Nature
, vol.222
, pp. 1148-1152
-
-
De Clercq, E.1
Merigan, T.C.2
-
11
-
-
0014961922
-
Increase in antiviral activity of polynucleotides by thermal activation
-
De Clercq E, Wells RD, Merigan TC. Increase in antiviral activity of polynucleotides by thermal activation. Nature 1970; 226:364-6.
-
(1970)
Nature
, vol.226
, pp. 364-366
-
-
De Clercq, E.1
Wells, R.D.2
Merigan, T.C.3
-
12
-
-
0015242958
-
Thermal activation of the antiviral activity of synthetic double-stranded polyribonucleotides
-
De Clercq E, Wells RD, Grant RC, Merigan TC. Thermal activation of the antiviral activity of synthetic double-stranded polyribonucleotides. J Mol Biol 1971; 56:83-100.
-
(1971)
J Mol Biol
, vol.56
, pp. 83-100
-
-
De Clercq, E.1
Wells, R.D.2
Grant, R.C.3
Merigan, T.C.4
-
13
-
-
0014672877
-
Interferon induction increased through chemical modification of a synthetic polyribonucleotide
-
De Clercq E, Eckstein F, Merigan TC. Interferon induction increased through chemical modification of a synthetic polyribonucleotide. Science 1969; 165:1137-9.
-
(1969)
Science
, vol.165
, pp. 1137-1139
-
-
De Clercq, E.1
Eckstein, F.2
Merigan, T.C.3
-
14
-
-
33748866662
-
Modified RNA aids fight against viral diseases
-
23 June
-
Modified RNA aids fight against viral diseases. Chem Eng News 1969; 23 June:17-8.
-
(1969)
Chem Eng News
, pp. 17-18
-
-
-
15
-
-
0014830374
-
The role of interferon in the protective effect of a synthetic double-stranded polyribonucleotide against intranasal vesicular stomatitis virus challenge in mice
-
De Clercq E, Nuwer MR, Merigan TC. The role of interferon in the protective effect of a synthetic double-stranded polyribonucleotide against intranasal vesicular stomatitis virus challenge in mice. J Clin Invest 1970; 49:1565-77.
-
(1970)
J Clin Invest
, vol.49
, pp. 1565-1577
-
-
De Clercq, E.1
Nuwer, M.R.2
Merigan, T.C.3
-
16
-
-
84965951084
-
Moloney sarcoma virus-induced tumors in mice: Inhibition or stimulation by poly(rI)-poly(rC)
-
De Clercq E, Merigan TC. Moloney sarcoma virus-induced tumors in mice: inhibition or stimulation by poly(rI)-poly(rC). Proc Soc Exp Biol Med 1971; 137:590-4.
-
(1971)
Proc Soc Exp Biol Med
, vol.137
, pp. 590-594
-
-
De Clercq, E.1
Merigan, T.C.2
-
17
-
-
0015229173
-
Antiviral activity of polyribocytidylic acid in cells primed with polyriboinosinic acid
-
De Clercq E, De Somer P. Antiviral activity of polyribocytidylic acid in cells primed with polyriboinosinic acid. Science 1971; 173:260-2.
-
(1971)
Science
, vol.173
, pp. 260-262
-
-
De Clercq, E.1
De Somer, P.2
-
18
-
-
0017105950
-
Antiviral activity of poly(7-deazainosinic acid)-derived complexes in vitro and in vivo
-
De Clercq E, Edy VG, Torrence PF, Water JA, Witkop B. Antiviral activity of poly(7-deazainosinic acid)-derived complexes in vitro and in vivo. Mol Pharmacol 1976; 12:1045-51.
-
(1976)
Mol Pharmacol
, vol.12
, pp. 1045-1051
-
-
De Clercq, E.1
Edy, V.G.2
Torrence, P.F.3
Water, J.A.4
Witkop, B.5
-
20
-
-
0016311342
-
Viral infection and host defense
-
Carter WA, De Clercq E. Viral infection and host defense. Science 1974; 186:1172-8.
-
(1974)
Science
, vol.186
, pp. 1172-1178
-
-
Carter, W.A.1
De Clercq, E.2
-
21
-
-
1642348819
-
Immunology. After the toll rush
-
O'Neill LA. Immunology. After the toll rush. Science 2004; 303:1481-2.
-
(2004)
Science
, vol.303
, pp. 1481-1482
-
-
O'Neill, L.A.1
-
22
-
-
0017186994
-
Effect of human leukocyte interferon on hepatitis B virus infection in patients with chronic active hepatitis
-
Greenberg HB, Pollard RB, Lutwick LI, Gregory PB, Robinson WS, Merigan TC. Effect of human leukocyte interferon on hepatitis B virus infection in patients with chronic active hepatitis. N Engl J Med 1976; 295:517-22.
-
(1976)
N Engl J Med
, vol.295
, pp. 517-522
-
-
Greenberg, H.B.1
Pollard, R.B.2
Lutwick, L.I.3
Gregory, P.B.4
Robinson, W.S.5
Merigan, T.C.6
-
23
-
-
0142126681
-
Clinical potential of the acyclic nucleoside phosphonates cidofovir, adefovir, and tenofovir in treatment of DNA virus and retrovirus infections
-
De Clercq E. Clinical potential of the acyclic nucleoside phosphonates cidofovir, adefovir, and tenofovir in treatment of DNA virus and retrovirus infections. Clin Microbiol Rev 2003; 16:569-96.
-
(2003)
Clin Microbiol Rev
, vol.16
, pp. 569-596
-
-
De Clercq, E.1
-
24
-
-
0022450584
-
A novel selective broad-spectrum anti-DNA virus agent
-
De Clercq E, Holý A, Rosenberg I, Sakuma T, Balzarini J, Maudgal PC. A novel selective broad-spectrum anti-DNA virus agent. Nature 1986; 323:464-7.
-
(1986)
Nature
, vol.323
, pp. 464-467
-
-
De Clercq, E.1
Holý, A.2
Rosenberg, I.3
Sakuma, T.4
Balzarini, J.5
Maudgal, P.C.6
-
25
-
-
0037468406
-
Adefovir dipivoxil for the treatment of hepatitis B e antigen-negative chronic hepatitis B
-
Hadziyannis SJ, Tassopoulos NC, Heathcote EJ, et al. Adefovir dipivoxil for the treatment of hepatitis B e antigen-negative chronic hepatitis B. N Engl J Med 2003; 348:800-7.
-
(2003)
N Engl J Med
, vol.348
, pp. 800-807
-
-
Hadziyannis, S.J.1
Tassopoulos, N.C.2
Heathcote, E.J.3
-
26
-
-
0037468421
-
Adefovir dipivoxil for the treatment of hepatitis B e antigen-positive chronic hepatitis B
-
Marcellin P, Chang TT, Lim SG, et al. Adefovir dipivoxil for the treatment of hepatitis B e antigen-positive chronic hepatitis B. N Engl J Med 2003; 348:808-16.
-
(2003)
N Engl J Med
, vol.348
, pp. 808-816
-
-
Marcellin, P.1
Chang, T.T.2
Lim, S.G.3
-
27
-
-
2342451795
-
Potential of acyclic nucleoside phosphonates in the treatment of DNA virus and retrovirus infections
-
De Clercq E. Potential of acyclic nucleoside phosphonates in the treatment of DNA virus and retrovirus infections. Expert Rev Anti Infect Ther 2003; 1:21-43.
-
(2003)
Expert Rev Anti Infect Ther
, vol.1
, pp. 21-43
-
-
De Clercq, E.1
-
28
-
-
0025834476
-
Immunomodulatory activity of 9-(2-phosphonylmethoxyethyl)adenine (PMEA), a potent anti-HIV nucleotide analogue, on in vivo murine models
-
Del Gobbo V, Foli A, Balzarini J, et al. Immunomodulatory activity of 9-(2-phosphonylmethoxyethyl)adenine (PMEA), a potent anti-HIV nucleotide analogue, on in vivo murine models. Antiviral Res 1991; 16:65-75.
-
(1991)
Antiviral Res
, vol.16
, pp. 65-75
-
-
Del Gobbo, V.1
Foli, A.2
Balzarini, J.3
-
29
-
-
0027976251
-
Enhancement of natural killer activity and interferon induction by different acyclic nucleoside phosphonates
-
Calio R, Villani N, Balestra E, et al. Enhancement of natural killer activity and interferon induction by different acyclic nucleoside phosphonates. Antiviral Res 1994; 23:77-89.
-
(1994)
Antiviral Res
, vol.23
, pp. 77-89
-
-
Calio, R.1
Villani, N.2
Balestra, E.3
-
30
-
-
0041379823
-
6-substituted adenines, and 2,6-diaminopurines
-
6-substituted adenines, and 2,6-diaminopurines. Eur J Pharmacol 2003; 475:149-59.
-
(2003)
Eur J Pharmacol
, vol.475
, pp. 149-159
-
-
Zídek, Z.1
Potmesil, P.2
Kmoníèková, E.3
Holý, A.4
-
31
-
-
1542378867
-
Peginterferon-α2a and ribavirin combination therapy in chronic hepatitis C
-
Hadziyannis SJ, Sette H Jr, Morgan TR, et al. Peginterferon-α2a and ribavirin combination therapy in chronic hepatitis C. Ann Intern Med 2004; 140:346-55.
-
(2004)
Ann Intern Med
, vol.140
, pp. 346-355
-
-
Hadziyannis, S.J.1
Sette Jr., H.2
Morgan, T.R.3
-
32
-
-
0019312944
-
Isolation and structure of a human fibroblast interferon gene
-
Derynck R, Content J, De Clercq E, et al. Isolation and structure of a human fibroblast interferon gene. Nature 1980; 285:542-7.
-
(1980)
Nature
, vol.285
, pp. 542-547
-
-
Derynck, R.1
Content, J.2
De Clercq, E.3
-
33
-
-
0019306804
-
Expression of human fibroblast interferon gene in Escherichia coli
-
Derynck R, Remaut E, Saman E, et al. Expression of human fibroblast interferon gene in Escherichia coli. Nature 1980; 287:193-7.
-
(1980)
Nature
, vol.287
, pp. 193-197
-
-
Derynck, R.1
Remaut, E.2
Saman, E.3
-
34
-
-
0345601517
-
Randomised double-blind placebo-controlled study of interferon β-la relapsing/remitting multiple sclerosis
-
PRISMS (Prevention of Relapses and Disability by Interferon β-la Subcutaneously in Multiple Sclerosis) Study Group. Randomised double-blind placebo-controlled study of interferon β-la relapsing/remitting multiple sclerosis. Lancet 1998; 352:1498-504.
-
(1998)
Lancet
, vol.352
, pp. 1498-1504
-
-
-
35
-
-
0141758383
-
Interferon-β in the treatment of relapsing-remitting multiple sclerosis
-
Revel M. Interferon-β in the treatment of relapsing-remitting multiple sclerosis. Pharmacol Ther 2003; 100:49-62.
-
(2003)
Pharmacol Ther
, vol.100
, pp. 49-62
-
-
Revel, M.1
-
36
-
-
0043200981
-
Treatment of SARS with human interferons
-
Cinatl J, Morgenstern B, Bauer G, Chandra P, Rabenau H, Doerr HW. Treatment of SARS with human interferons. Lancet 2003; 362:293-4.
-
(2003)
Lancet
, vol.362
, pp. 293-294
-
-
Cinatl, J.1
Morgenstern, B.2
Bauer, G.3
Chandra, P.4
Rabenau, H.5
Doerr, H.W.6
-
37
-
-
2342645538
-
Pegylated interferon-α protects type 1 pneumocytes against SARS coronavirus (SCV) infection in macaques
-
Haagmans BL, Kuiken T, Martina BE, et al. Pegylated interferon-α protects type 1 pneumocytes against SARS coronavirus (SCV) infection in macaques. Nat Med 2004; 10:290-3.
-
(2004)
Nat Med
, vol.10
, pp. 290-293
-
-
Haagmans, B.L.1
Kuiken, T.2
Martina, B.E.3
-
39
-
-
0014331524
-
Effect of interferon, polyacrylic acid, and polymethacrylic acid on tail lesions in mice infected with vaccinia virus
-
De Clercq E, De Somer P. Effect of interferon, polyacrylic acid, and polymethacrylic acid on tail lesions in mice infected with vaccinia virus. Appl Microbiol 1968; 16:1314-9.
-
(1968)
Appl Microbiol
, vol.16
, pp. 1314-1319
-
-
De Clercq, E.1
De Somer, P.2
-
40
-
-
0037287574
-
Defense against filoviruses used as biological weapons
-
Bray M. Defense against filoviruses used as biological weapons. Antiviral Res 2003; 57:53-60.
-
(2003)
Antiviral Res
, vol.57
, pp. 53-60
-
-
Bray, M.1
-
41
-
-
0034096583
-
Treatment of lethal Ebola virus infection in mice with a single dose of an S-adenosyl-L-homocysteine hydrolase inhibitor
-
Bray M, Driscoll J, Huggins JW. Treatment of lethal Ebola virus infection in mice with a single dose of an S-adenosyl-L-homocysteine hydrolase inhibitor. Antiviral Res 2000; 45:135-47.
-
(2000)
Antiviral Res
, vol.45
, pp. 135-147
-
-
Bray, M.1
Driscoll, J.2
Huggins, J.W.3
-
42
-
-
0033066490
-
Evaluation of immune globulin and recombinant interferon-α2b for treatment of experimental Ebola virus infections
-
Jahrling PB, Geisbert TW, Geisbert JB, et al. Evaluation of immune globulin and recombinant interferon-α2b for treatment of experimental Ebola virus infections. J Infect Dis 1999; 179(Suppl 1):S224-34.
-
(1999)
J Infect Dis
, vol.179
, Issue.SUPPL. 1
-
-
Jahrling, P.B.1
Geisbert, T.W.2
Geisbert, J.B.3
-
43
-
-
0014334374
-
Protective effect of interferon and polyacrylic acid in newborn mice infected with a lethal dose of vesicular stomatitis virus
-
De Clercq E, De Somer P. Protective effect of interferon and polyacrylic acid in newborn mice infected with a lethal dose of vesicular stomatitis virus. Life Sci 1968; 7:925-33.
-
(1968)
Life Sci
, vol.7
, pp. 925-933
-
-
De Clercq, E.1
De Somer, P.2
-
44
-
-
0024407007
-
Broad-spectrum antiviral activities of neplanocin A, 3-deazaneplanocin A and their 5′-nor derivatives
-
De Clercq E, Cools M, Balzarini J, et al. Broad-spectrum antiviral activities of neplanocin A, 3-deazaneplanocin A and their 5′-nor derivatives. Antimicrob Agents Chemother 1989; 33:1291-7.
-
(1989)
Antimicrob Agents Chemother
, vol.33
, pp. 1291-1297
-
-
De Clercq, E.1
Cools, M.2
Balzarini, J.3
-
45
-
-
4444256678
-
Antivirals and antiviral strategies
-
De Clercq E. Antivirals and antiviral strategies. Nat Rev Microbiol 2004; 2:704-20.
-
(2004)
Nat Rev Microbiol
, vol.2
, pp. 704-720
-
-
De Clercq, E.1
-
46
-
-
0035997942
-
3-Deazaneplanocin A induces massively increased interferon-α production in Ebola virus-infected mice
-
Bray M, Raymond JL, Geisbert T, Baker RO. 3-Deazaneplanocin A induces massively increased interferon-α production in Ebola virus-infected mice. Antiviral Res 2002; 55:151-9.
-
(2002)
Antiviral Res
, vol.55
, pp. 151-159
-
-
Bray, M.1
Raymond, J.L.2
Geisbert, T.3
Baker, R.O.4
-
47
-
-
0037310988
-
Interferons, interferon inducers, and interferon-ribavirin in treatment of flavivirus-induced encephalitis in mice
-
Leyssen P, Drosten C, Paning M, et al. Interferons, interferon inducers, and interferon-ribavirin in treatment of flavivirus-induced encephalitis in mice. Antimicrob Agents Chemother 2003; 47:777-82.
-
(2003)
Antimicrob Agents Chemother
, vol.47
, pp. 777-782
-
-
Leyssen, P.1
Drosten, C.2
Paning, M.3
|