Low versus high doses of topiramate in the preventive treatment of migraine;Dosis bajas frente a dosis altas de topiramato en el tratamiento preventivo de la migraña

Neurologia

Volumn 24, Issue 9, 2009, Pages 808-810

  Cacabelos, P ^a   El Berdei, Y ^a   Rivas, M T ^a   Riveira, C ^a   Conde, A ^a   Pascual, Julio ^b  

^a HOSPITAL UNIVERSITARIO DE SALAMANCA   (Spain)

^b HOSPITAL UNIVERSITARIO MARQUÉS DE VALDECILLA   (Spain)

Author keywords

Migraine; Tolerability; Topiramate

Indexed keywords

TOPIRAMATE;

ARTICLE; CLINICAL TRIAL; DRUG DOSE INCREASE; DRUG EFFICACY; DRUG MEGADOSE; DRUG TOLERABILITY; HUMAN; LOW DRUG DOSE; MAJOR CLINICAL STUDY; MIGRAINE;

ADULT; AGED; ANTICONVULSANTS; CLINICAL TRIALS AS TOPIC; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; FRUCTOSE; HUMANS; MALE; MIDDLE AGED; MIGRAINE DISORDERS; TREATMENT OUTCOME; YOUNG ADULT;

EID: 75849117041     PISSN: 02134853     EISSN: 15781968     Source Type: Journal    
DOI: None     Document Type: Article

References (9)

1. Brandes JL, Saper JR, Diamond M, Couch JR, Lewis DW, Schmitt J, et al. Topiramate for migraine prevention: a randomized controlled trial. JAMA 2004;291:965-73.
2. Silberstein SD, Neto W, Schmiditt J, Jacobs D, MIGR-001 Study Group. Topiramate in migraine prevention: results of a large controlled trial. Arch Neurol 2004;61:490-5.
3. Diener HC, Tfelt-Hansen P, Dahlof C, Laínez MJ, Sandrini G, Wang SJ, et al. Topiramate in migraine prophylaxis. Results from a placebo-controlled trial with propranolol as an active control. J Neurol 2004;251:943-50.
4. Pascual J, Sánchez del Río M, Mateos V, Láinez JM, Hernández-Gallego J, Leira R, et al. Topiramate for patients with refractory migraine: an observational, multicenter study in Spain. Neurología 2003;18:364-7.
5. nd ed. Cephalalgia 2004;24(Suppl. 1):9-160.
6. Grupo de Estudio de Cefaleas de la SEN. Guías para el diagnóstico y tratamiento de las cefaleas. En: Mateos V, editor. Barcelona: Prous Science, 2007.
7. Silvestrini M, Bartolini M, Coccia M, Baruffaldi R, Taffi R, Provinciali L. Topiramate in the treatment of chronic migraine. Cephalalgia 2003;23:820-4.
8. Silberstein SD, Lipton RB, Dodick DW, Freitag FG, Ramadan N, Mathew N, et al. Efficacy and safety of topiramate for the treatment of chronic migraine: a randomized, double-blind, placebo-controlled trial. Headache 2007;47:170-80.
9. Diener HC, Bussone G, Van Oene JC, Lahaye M, Schwalen S, Goadsby PJ; TOPMAT-MIG-201 (TOP-CHROMR) Study Group. Topiramate reduces headache days in chronic migraine: a rando-mized, double-blind, placebo-controlled study. Cephalalgia 2007;27:814-23.