Efficacy and safety of topiramate for the treatment of chronic migraine: A randomized, double-blind, placebo-controlled trial

Headache

Volumn 47, Issue 2, 2007, Pages 170-180

  Silberstein, Stephen D ^a,k   Lipton, Richard B ^b   Dodick, David W ^c   Freitag, Frederick G ^d   Ramadan, Nabih ^e   Mathew, Ninan ^f   Brandes, Jan L ^g   Bigal, Marcelo ^b   Saper, Joel ^h   Ascher, Steven ⁱ   Jordan, Donna M ^j   Greenberg, Steven J ^j   Hulihan, Joseph ^j  

^a JEFFERSON HEADACHE CENTER   (United States)

^b ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^c MAYO CLINIC   (United States)

^d DIAMOND HEADACHE CLINIC   (United States)

^e ROSALIND FRANKLIN UNIVERSITY OF MEDICINE AND SCIENCE   (United States)

^f Houston Headache Clinic   (United States)

^g Nashville Neuroscience Group   (United States)

^h Michigan Head Pain and Neurological Institute   (United States)

ⁱ JANSSEN RESEARCH AND DEVELOPMENT   (United States)

^j Ortho McNeil Pharmaceutical Incorporated   (United States)

^k THOMAS JEFFERSON UNIVERSITY   (United States)

more..

Author keywords

Chronic daily headache; Clinical trial; Migraine; Preventive treatment; Topiramate; Transformed migraine

Indexed keywords

PLACEBO; TOPIRAMATE;

ADULT; AGED; ANALYSIS OF COVARIANCE; ANOREXIA; ARTICLE; ATTENTION; CLINICAL EXAMINATION; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIZZINESS; DOUBLE BLIND PROCEDURE; DRUG DOSE ESCALATION; DRUG DOSE TITRATION; DRUG EFFICACY; DRUG FATALITY; DRUG SAFETY; DRUG TOLERABILITY; DRUG WITHDRAWAL; FATIGUE; FEMALE; HEADACHE; HUMAN; HYPESTHESIA; INJURY; LABORATORY TEST; MAINTENANCE THERAPY; MAJOR CLINICAL STUDY; MALE; MAXIMUM TOLERATED DOSE; MEMORY; MENTAL CONCENTRATION; MULTICENTER STUDY; NAUSEA; NEUROLOGIC EXAMINATION; PARESTHESIA; PHYSICAL EXAMINATION; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SIDE EFFECT; SINUSITIS; SOMNOLENCE; STATISTICAL SIGNIFICANCE; TASTE DISORDER; TASTE PERVERSION; TRANSFORMED MIGRAINE; TREATMENT DURATION; UPPER RESPIRATORY TRACT INFECTION; WEIGHT REDUCTION; XEROSTOMIA;

ADOLESCENT; ADULT; AGED; ANTICONVULSANTS; CHRONIC DISEASE; DOSE-RESPONSE RELATIONSHIP, DRUG; DOUBLE-BLIND METHOD; FEMALE; FRUCTOSE; HUMANS; MALE; MIDDLE AGED; MIGRAINE DISORDERS; TREATMENT OUTCOME;

EID: 33846998336     PISSN: 00178748     EISSN: 15264610     Source Type: Journal    
DOI: 10.1111/j.1526-4610.2006.00684.x     Document Type: Article

References (27)

1. Silberstein SD, Lipton RB. Chronic daily headache. Curr Opin Neurol. 2000;13:277-283.
2. Headache Classification Committee of the International Headache Society. The International Classification of Headache Disorders (2nd ed.). Cephalalgia. 2004;24(suppl 1):1-160.
3. Olesen J, Bousser MG, Diener HC, et al. (Headache Classification Committee). New appendix criteria open for a broader concept of chronic migraine. Cephalalgia. 2006;26:742-746.
4. Mathew NT. Chronic refractory headache. Neurology. 1993;43:S26-S33.
5. Mathew NT. Transformed migraine. Cephalalgia. 1993;13:78-83.
6. Mathew NT, Reuveni U, Perez F. Transformed or evolutive migraine. Headache. 1987;27:102-106.
7. Bigal ME, Tepper SJ, Sheftell FD, Rapoport AM, Lipton RB. Field testing alternative criteria for chronic migraine. Cephalalgia. 2006;26:477-482.
8. Bigal ME, Rapoport AM, Lipton RB, Tepper SJ, Sheftell FD. Assessment of migraine disability using the migraine disability assessment (MIDAS) questionnaire: A comparison of chronic migraine with episodic migraine. Headache. 2003;43:336-342.
9. Zwart JA, Dyb G, Hagen K, Svebak S, Stovner LJ, Holmen J. Analgesic overuse among subjects with headache, neck, and low-back pain. Neurology. 2004;62:1540-1544.
10. Limmroth V, Katsarava Z, Fritsche G, Przywara S, Diener HC. Features of medication overuse headache following overuse of different acute headache drugs. Neurology. 2002;59:1011-1014.
11. Olesen J, Tfelt-Hansen P, Ramadan N, Goadsby PJ, Welch KMA. The Headaches. Philadelphia, Pennsylvania: Lippincott, Williams &Wilkins; 2005.
12. Silberstein SD. Practice parameter: Evidence-based guidelines formigraine headache (an evidence-based review): Report of the Quality Standards Subcommittee of the American Academy of Neurology. Neurology. 2000;55:754-762.
13. Ramadan NM, Silberstein SD, Freitag FG, Gilbert TT, Frishberg BMfor the US Headache Consortium. Evidence-based guidelines for migraine headache in the primary care setting: Pharmacological management for prevention of migraine. Available at: http://www.aan.com/professionals/practice/pdfs/gl0090.pdf. Accessed August 31, 2006.
14. Brandes JL, Saper JR, Diamond M, et al. D; MIGR-002 Study Group. Topiramate for migraine prevention: A randomized controlled trial. JAMA. 2004;291:965-973.
15. Silberstein SD, Neto W, Schmitt J, Jacobs D, MIGR-001 Study Group. Topiramate in migraine prevention: Results of a large controlled trial. Arch Neurol. 2004;61:490-495.
16. Diener HC, Tfelt-Hansen P, Dahlof C, et al. MIGR-003 Study Group. Topiramate in migraine prophylaxis - results from a placebo-controlled trial with propranolol as an active control. J Neurol. 2004;251:943-950.
17. Bussone G, Diener HC, Pfeil J, Schwalen S. Topiramate 100 mg/day in migraine prevention: A pooled analysis of double-blind randomised controlled trials. Int J Clin Pract. 2005;59:961-968.
18. Silvestrini M, Bartolini M, Coccia M, Baruffaldi R, Taffi R, Provinciali L. Topiramate in the treatment of chronic migraine. Cephalalgia. 2003;23:820-824.
19. Bartolini M, Silvestrini M, Taffi R, et al. Efficacy of topiramate and valproate in chronic migraine. Clin Neuropharmacol. 2005;28:277-279.
20. Silberstein SD, Lipton RB, Sliwinski M. Classification of daily and near-daily headaches: Field trial of revised HIS criteria. Neurology. 1996;47:871-875.
21. International Headache Society Classification. Cephalalgia. 1998;8(suppl 7):1-96.
22. Stewart WF, Lipton RB, Whyte J, et al. An international study to assess reliability of the Migraine Disability Assessment (MIDAS) score. Neurology. 1999;53:988-994.
23. Bauer P. Multiple testing in clinical trials. Stat Med. 1991;10:871-890.
24. Topamax® prescribing information. Ortho-McNeil Neurologics, Inc.; Titusville, NJ; June 2005.
25. Bigal ME, Lipton RB. When migraine progresses: Transformed or chronic migraine. Expert Rev Neurother. 2006;6:297-306.
26. Diener HC, Goadsby PJ. Migraine. In: Brandt T, Caplan L, Dichgans J, Diener HC, Kennard C, eds. Course and Treatment of Neurological Disorders. 2nd edition. San Diego, California: Academic Press; 2003:1-16.
27. Goadsby PJ, Lipton RB, Ferrari MD. Migraine - current understanding and treatment. N Engl J Med. 2002;346:257-270.