-
1
-
-
33646568784
-
Patterns of cancer incidence, mortality, and prevalence across five continents: Defining priorities to reduce cancer disparities in different geographic regions of the world
-
Kamangar F, Dores GM, Anderson WF. Patterns of cancer incidence, mortality, and prevalence across five continents: defining priorities to reduce cancer disparities in different geographic regions of the world. J Clin Oncol 2006; 24 (14): 2137-2150
-
(2006)
J Clin Oncol
, vol.24
, Issue.14
, pp. 2137-2150
-
-
Kamangar, F.1
Dores, G.M.2
Anderson, W.F.3
-
3
-
-
34548457234
-
The IASLC lung cancer staging project: Proposals for the revision of the TNM stage groupings in the forthcoming (seventh) edition of the TNM classification of malignant tumours
-
DOI 10.1097/JTO.0b013e31812f3c1a, PII 0124389420070800000006
-
Goldstraw P, Crowley J, Chansky K, et al. The IASLC Lung Cancer Staging Project: proposals for the revision of the TNM stage groupings in the forthcoming (seventh) edition of the TNM classification of malignant tumours. J Thorac Oncol 2007; 2: 706-714 (Pubitemid 47357522)
-
(2007)
Journal of Thoracic Oncology
, vol.2
, Issue.8
, pp. 706-714
-
-
Goldstraw, P.1
Crowley, J.2
Chansky, K.3
Giroux, D.J.4
Groome, P.A.5
Rami-Porta, R.6
Postmus, P.E.7
Rusch, V.8
Sobin, L.9
-
4
-
-
0028843552
-
Chemo-therapy in non-small cell lung cancer: A meta-analysis using updated data on individual patients from 52 randomised clinical trials
-
Non-small Cell Lung Cancer Collaborative Group
-
Non-small Cell Lung Cancer Collaborative Group. Chemo-therapy in non-small cell lung cancer: a meta-analysis using updated data on individual patients from 52 randomised clinical trials. BMJ 1995; 311: 899
-
(1995)
BMJ
, vol.311
, pp. 899
-
-
-
5
-
-
53749097825
-
Chemo-therapy in addition to supportive care improves survival in advanced non-small-cell lung cancer: A systematic review and meta-analysis of individual patient data from 16 randomized controlled trials
-
Non-small Cell Lung Cancer Collaborative Group
-
Non-small Cell Lung Cancer Collaborative Group. Chemo-therapy in addition to supportive care improves survival in advanced non-small-cell lung cancer: a systematic review and meta-analysis of individual patient data from 16 randomized controlled trials. J Clin Oncol 2008; 26 (28): 4617
-
(2008)
J Clin Oncol
, vol.26
, Issue.28
, pp. 4617
-
-
-
6
-
-
0031861215
-
Randomized trial comparing cisplatin with cisplatin plus vinorelbine in the treatment of advanced non-small-cell lung cancer: A Southwest Oncology Group study
-
Wozniak AJ, Crowley JJ, Balcerzak SP, et al. Randomized trial comparing cisplatin with cisplatin plus vinorelbine in the treatment of advanced non-small-cell lung cancer: a Southwest Oncology Group study. J Clin Oncol 1998; 16 (7): 2459-2465
-
(1998)
J Clin Oncol
, vol.16
, Issue.7
, pp. 2459-2465
-
-
Wozniak, A.J.1
Crowley, J.J.2
Balcerzak, S.P.3
-
7
-
-
17344384668
-
Phase III trial of gemcitabine plus cisplatin versus cisplatin alone in patients with locally advanced or metastatic non-small-cell lung cancer
-
Sandler AB, Nemunaitis J, Denham C, et al. Phase III trial of gemcitabine plus cisplatin versus cisplatin alone in patients with locally advanced or metastatic non-small-cell lung cancer. J Clin Oncol 2000; 18 (1): 122-130
-
(2000)
J Clin Oncol
, vol.18
, Issue.1
, pp. 122-130
-
-
Sandler, A.B.1
Nemunaitis, J.2
Denham, C.3
-
8
-
-
16644396077
-
Single-agent versus combination chemotherapy in advanced non-small cell lung cancer: The Cancer and Leukemia Group B (Study 9730)
-
Lilenbaum RC, Herndon JE, List MA, et al. Single-agent versus combination chemotherapy in advanced non-small cell lung cancer: the Cancer and Leukemia Group B (Study 9730). J Clin Oncol 2005; 23 (1): 190-196
-
(2005)
J Clin Oncol
, vol.23
, Issue.1
, pp. 190-196
-
-
Lilenbaum, R.C.1
Herndon, J.E.2
List, M.A.3
-
9
-
-
3843131593
-
Docetaxel and carboplatin once every three weeks versus weekly docetaxel in advanced non-small cell lung cancer (NSCLC): An interim analysis of a multicenter phase III trial [abstract]
-
Groen H, Schramel FM, van der Hoeven JJM, et al. Docetaxel and carboplatin once every three weeks versus weekly docetaxel in advanced non-small cell lung cancer (NSCLC): an interim analysis of a multicenter phase III trial [abstract]. Proc Am Soc Clin Oncol 2003; 22: 623
-
(2003)
Proc Am Soc Clin Oncol
, vol.22
, pp. 623
-
-
Groen, H.1
Schramel, F.M.2
Van Der Hoeven, J.J.M.3
-
10
-
-
33644684204
-
Phase III trial of gemcitabine plus carboplatin versus single-agent gemci-tabine in the treatment of locally advanced or metastatic non-small-cell lung cancer
-
Sederholm C, Hillerdal G, Lamberg K, et al. Phase III trial of gemcitabine plus carboplatin versus single-agent gemci-tabine in the treatment of locally advanced or metastatic non-small-cell lung cancer: the Swedish Lung Cancer Study Group. J Clin Oncol 2005; 23 (33): 8380-8388
-
(2005)
J Clin Oncol
, vol.23
, Issue.33
, pp. 8380-8388
-
-
Sederholm, C.1
Hillerdal, G.2
Lamberg, K.3
-
11
-
-
34347379142
-
Cisplatin-versus carboplatin-based chemotherapy in first-line treatment of advanced non-small-cell lung cancer: An individual patient data meta-analysis
-
Ardizzoni A, Boni L, Tiseo M, et al. Cisplatin-versus carboplatin-based chemotherapy in first-line treatment of advanced non-small-cell lung cancer: an individual patient data meta-analysis. J Natl Cancer Inst 2007; 99 (11): 847-857
-
(2007)
J Natl Cancer Inst
, vol.99
, Issue.11
, pp. 847-857
-
-
Ardizzoni, A.1
Boni, L.2
Tiseo, M.3
-
12
-
-
75749138090
-
CISCA (cisplatin vs. carboplatin) meta-analysis: An individual patient data meta-analysis comparing cisplatin versus carboplatin-based chemotherapy in first-line treatment of advanced non-small cell lung cancer (NSCLC) [abstract no. 7011 plus oral presentation]
-
Jun. 2-6; Atlanta (GA) [online]. Accessed 2010 Jan 22
-
Ardizzoni A. CISCA (cisplatin vs. carboplatin) meta-analysis: an individual patient data meta-analysis comparing cisplatin versus carboplatin-based chemotherapy in first-line treatment of advanced non-small cell lung cancer (NSCLC) [abstract no. 7011 plus oral presentation]. Lung cancer I. 2006 ASCO Annual Meeting; 2006 Jun 2-6; Atlanta (GA) [online]. Available from URL: http://www.asco.org/ASCOv2/MultiMedia/Virtual+Meeting?&vmview=vm- session-presentations-view&confID=40&sessionID =369 [Accessed 2010 Jan 22]
-
(2006)
Lung Cancer I. 2006 ASCO Annual Meeting
-
-
Ardizzoni, A.1
-
13
-
-
0042413836
-
Randomized, multinational, phase III study of docetaxel plus platinum combinations versus vinorelbine plus cisplatin for advanced non-small cell lung cancer: The TAX 326 study group
-
Fossella F, Pereira JR, von Pawel J, et al. Randomized, multinational, phase III study of docetaxel plus platinum combinations versus vinorelbine plus cisplatin for advanced non-small cell lung cancer: the TAX 326 study group. J Clin Oncol 2003; 21: 3016-3024
-
(2003)
J Clin Oncol
, vol.21
, pp. 3016-3024
-
-
Fossella, F.1
Pereira, J.R.2
Von Pawel, J.3
-
14
-
-
0037050352
-
Comparison of four chemotherapy regimens for advanced non-small cell lung cancer
-
Schiller JH, Harrington D, Belani CP, et al. Comparison of four chemotherapy regimens for advanced non-small cell lung cancer. N Engl J Med 2002; 346: 92-98
-
(2002)
N Engl J Med
, vol.346
, pp. 92-98
-
-
Schiller, J.H.1
Harrington, D.2
Belani, C.P.3
-
15
-
-
49049089802
-
Phase III study comparing cisplatin plus gemcitabine with cisplatin plus pe-metrexed in chemotherapy-naive patients with advanced-stage non-small-cell lung cancer
-
Scagliotti GV, Parikh P, von Pawel J, et al. Phase III study comparing cisplatin plus gemcitabine with cisplatin plus pe-metrexed in chemotherapy-naive patients with advanced-stage non-small-cell lung cancer. J Clin Oncol 2008; 26: 3543-3551
-
(2008)
J Clin Oncol
, vol.26
, pp. 3543-3551
-
-
Scagliotti, G.V.1
Parikh, P.2
Von Pawel, J.3
-
16
-
-
33845490014
-
Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancer
-
DOI 10.1056/NEJMoa061884
-
Sandler A, Gray R, Perry MC, et al. Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancer. N Engl J Med 2006; 355: 2542-2550 (Pubitemid 44917502)
-
(2006)
New England Journal of Medicine
, vol.355
, Issue.24
, pp. 2542-2550
-
-
Sandler, A.1
Gray, R.2
Perry, M.C.3
Brahmer, J.4
Schiller, J.H.5
Dowlati, A.6
Lilenbaum, R.7
Johnson, D.H.8
-
17
-
-
2942657615
-
Random-ized phase II trial comparing bevacizumab plus carboplatin and paclitaxel with carboplatin and paclitaxel alone in previously untreated locally advanced or metastatic non-small-cell lung cancer
-
Johnson DH, Fehrenbacher L, Novotny WF, et al. Random-ized phase II trial comparing bevacizumab plus carboplatin and paclitaxel with carboplatin and paclitaxel alone in previously untreated locally advanced or metastatic non-small-cell lung cancer. J Clin Oncol 2004; 22: 2184-2191
-
(2004)
J Clin Oncol
, vol.22
, pp. 2184-2191
-
-
Johnson, D.H.1
Fehrenbacher, L.2
Novotny, W.F.3
-
18
-
-
49749101701
-
Safety of bevacizumab (Bv) therapy in combination with chemotherapy in subjects with non-small cell lung cancer (NSCLC) treated on ATLAS [abstract]
-
Polikoff J, Hainsworth JD, Fehrenbacher L, et al. Safety of bevacizumab (Bv) therapy in combination with chemotherapy in subjects with non-small cell lung cancer (NSCLC) treated on ATLAS [abstract]. J Clin Oncol 2008; 26: 8079
-
(2008)
J Clin Oncol
, vol.26
, pp. 8079
-
-
Polikoff, J.1
Hainsworth, J.D.2
Fehrenbacher, L.3
-
19
-
-
49749127690
-
Acceptable safety of bevacizumab therapy in patients with brain metastases due to non-small cell lung cancer [abstract]
-
Akerley WL, Langer CJ, Oh Y, et al. Acceptable safety of bevacizumab therapy in patients with brain metastases due to non-small cell lung cancer [abstract]. J Clin Oncol 2008; 26: 8043
-
(2008)
J Clin Oncol
, vol.26
, pp. 8043
-
-
Akerley, W.L.1
Langer, C.J.2
Oh, Y.3
-
20
-
-
65349154564
-
Preliminary treatment patterns and safety outcomes for non-small cell lung cancer (NSCLC) from ARIES, a bevacizumab treatment observational cohort study (OCS) [abstract]
-
Lynch TJ, Brahmer J, Fischbach N, et al. Preliminary treatment patterns and safety outcomes for non-small cell lung cancer (NSCLC) from ARIES, a bevacizumab treatment observational cohort study (OCS) [abstract]. J Clin Oncol 2008; 26: 8077
-
(2008)
J Clin Oncol
, vol.26
, pp. 8077
-
-
Lynch, T.J.1
Brahmer, J.2
Fischbach, N.3
-
21
-
-
62449124416
-
Phase III trial of cisplatin plus gemcitabine with either placebo or bevacizumab as first-line therapy for nonsquamous non-small-cell lung cancer: AVAiL
-
Reck M, von Pawel J, Zatloukal P, et al. Phase III trial of cisplatin plus gemcitabine with either placebo or bevacizumab as first-line therapy for nonsquamous non-small-cell lung cancer: AVAiL. J Clin Oncol 2009; 27 (8): 1227-1234
-
(2009)
J Clin Oncol
, vol.27
, Issue.8
, pp. 1227-1234
-
-
Reck, M.1
Von Pawel, J.2
Zatloukal, P.3
-
22
-
-
65349116059
-
Cetuximab plus chemotherapy in patients with advanced non-small-cell lung cancer (FLEX): An open-label randomised phase III trial
-
Pirker R, Pereira JR, Szczesna A, et al. Cetuximab plus chemotherapy in patients with advanced non-small-cell lung cancer (FLEX): an open-label randomised phase III trial. Lancet 2009; 373: 1525-1531
-
(2009)
Lancet
, vol.373
, pp. 1525-1531
-
-
Pirker, R.1
Pereira, J.R.2
Szczesna, A.3
-
23
-
-
62549097420
-
Overall survival results from the phase III trial BMS 099: Cetux-imab+taxane/carboplatin as 1st-line treatment for advanced NSCLC [abstract]
-
Lynch TJ, Patel T, Dreisbach L, et al. Overall survival results from the phase III trial BMS 099: cetux-imab+taxane/carboplatin as 1st-line treatment for advanced NSCLC [abstract]. J Thorac Oncol 2008; 2: S305
-
(2008)
J Thorac Oncol
, vol.2
-
-
Lynch, T.J.1
Patel, T.2
Dreisbach, L.3
-
24
-
-
1542503746
-
Gefitinib in combination with gemcitabine and cisplatin in advanced non-small-cell lung cancer: A phase III trial - INTACT 1
-
DOI 10.1200/JCO.2004.08.001
-
Giaccone G, Herbst RS, Manegold C, et al. Gefitinib in combination with gemcitabine and cisplatin in advanced non-small-cell lung cancer: a phase III trial-INTACT 1. J Clin Oncol 2004; 22 (5): 777-784 (Pubitemid 41103588)
-
(2004)
Journal of Clinical Oncology
, vol.22
, Issue.5
, pp. 777-784
-
-
Giaccone, G.1
Herbst, R.S.2
Manegold, C.3
Scagliotti, G.4
Rosell, R.5
Miller, V.6
Natale, R.B.7
Schiller, J.H.8
Von Pawel, J.9
Pluzanska, A.10
Gatzemeier, U.11
Grous, J.12
Ochs, J.S.13
Averbuch, S.D.14
Wolf, M.K.15
Rennie, P.16
Fandi, A.17
Johnson, D.H.18
-
25
-
-
1542713370
-
Gefitinib in combination with paclitaxel and carboplatin in advanced non-small-cell lung cancer: A phase III trial - INTACT 2
-
DOI 10.1200/JCO.2004.07.215
-
Herbst RS, Giaccone G, Schiller JH, et al. Gefitinib in combination with paclitaxel and carboplatin in advanced non-small-cell lung cancer: a phase III trial-INTACT 2. J Clin Oncol 2004; 22 (5): 785-794 (Pubitemid 41103589)
-
(2004)
Journal of Clinical Oncology
, vol.22
, Issue.5
, pp. 785-794
-
-
Herbst, R.S.1
Giaccone, G.2
Schiller, J.H.3
Natale, R.B.4
Miller, V.5
Manegold, C.6
Scagliotti, G.7
Rosell, R.8
Oliff, I.9
Reeves, J.A.10
Wolf, M.K.11
Krebs, A.D.12
Averbuch, S.D.13
Ochs, J.S.14
Grous, J.15
Fandi, A.16
Johnson, D.H.17
-
26
-
-
24944440830
-
On behalf of the TRIBUTE Investigator Group. TRIBUTE: A phase III trial of erlotinib hydrochloride (OSI-774) combined with carboplatin and paclitaxel chemotherapy in advanced non-small-cell lung cancer
-
Herbst RS, Prager D, Hermann R, et al., on behalf of the TRIBUTE Investigator Group. TRIBUTE: a phase III trial of erlotinib hydrochloride (OSI-774) combined with carboplatin and paclitaxel chemotherapy in advanced non-small-cell lung cancer. J Clin Oncol 2005; 23 (25): 5892-5899
-
(2005)
J Clin Oncol
, vol.23
, Issue.25
, pp. 5892-5899
-
-
Herbst, R.S.1
Prager, D.2
Hermann, R.3
-
27
-
-
4444238981
-
Results of a phase III trial of erlotinib (OSI-774) combined with cis-platin and gemcitabine (GC) chemotherapy in advanced non-small cell lung cancer (NSCLC) [abstract]
-
Gatzemeier U, Pluzanska A, Szczesna A, et al. Results of a phase III trial of erlotinib (OSI-774) combined with cis-platin and gemcitabine (GC) chemotherapy in advanced non-small cell lung cancer (NSCLC) [abstract]. Proc Am Soc Clin Oncol 2004; 23: 617
-
(2004)
Proc Am Soc Clin Oncol
, vol.23
, pp. 617
-
-
Gatzemeier, U.1
Pluzanska, A.2
Szczesna, A.3
-
29
-
-
75749105403
-
-
Dutch Society of Physicians for Pulmonology and Tubercu-losis. 2nd line erlotinib treatment with (out) chemotherapy of advanced non small cell lung cancer (NSCLC) (NVALT10) [ClinicalTrials.gov identifier NCT00835471] US National Institutes of Health, ClinicalTrials.gov [online] Accessed 2009 Dec 24
-
Dutch Society of Physicians for Pulmonology and Tubercu-losis. 2nd line erlotinib treatment with (out) chemotherapy of advanced non small cell lung cancer (NSCLC) (NVALT10) [ClinicalTrials.gov identifier NCT00835471]. US National Institutes of Health, ClinicalTrials.gov [online]. Available from URL: http://clinicaltrials.gov/ct2/show/NCT00835471?term=NCT00835471&rank=1 [Accessed 2009 Dec 24]
-
-
-
-
34
-
-
58249092152
-
Randomized phase II study of pulse erlotinib before or after carboplatin and paclitaxel in current or former smokers with advanced non-small-cell lung cancer
-
Riely G, Rizvi N, Kris M, et al. Randomized phase II study of pulse erlotinib before or after carboplatin and paclitaxel in current or former smokers with advanced non-small-cell lung cancer. J Clin Oncol 2009; 27: 264-270
-
(2009)
J Clin Oncol
, vol.27
, pp. 264-270
-
-
Riely, G.1
Rizvi, N.2
Kris, M.3
-
35
-
-
0034069620
-
Prospective ran-domized trial of docetaxel versus best supportive care in patients with non-small-cell lung cancer previously treated with platinum-based chemotherapy
-
Shepherd FA, Dancey J, Ramlau R, et al. Prospective ran-domized trial of docetaxel versus best supportive care in patients with non-small-cell lung cancer previously treated with platinum-based chemotherapy. J Clin Oncol 2000; 18 (10): 2095-2103
-
(2000)
J Clin Oncol
, vol.18
, Issue.10
, pp. 2095-2103
-
-
Shepherd, F.A.1
Dancey, J.2
Ramlau, R.3
-
36
-
-
2442661845
-
Randomized phase III trial of pemetrexed versus docetaxel in patients with non-small-cell lung cancer previously treated with chemotherapy
-
Hanna N, Shepherd FA, Fossella FV, et al. Randomized phase III trial of pemetrexed versus docetaxel in patients with non-small-cell lung cancer previously treated with chemotherapy. J Clin Oncol 2004; 22 (9): 1589-1597
-
(2004)
J Clin Oncol
, vol.22
, Issue.9
, pp. 1589-1597
-
-
Hanna, N.1
Shepherd, F.A.2
Fossella, F.V.3
-
37
-
-
42549116071
-
Is pemetrexed more effective in adenocarcinoma and large cell lung cancer than in squamous cell carcinoma? A retrospective analysis of a phase III trial of pemetrexed versus docetaxel in previously treated patients with advanced non-small cell lung cancer (NSCLC): P2-328
-
Sep. 2-6; Seoul. J Thorac Oncol 2007 Aug
-
Peterson P, Park K, Fossella FV, et al. Is pemetrexed more effective in adenocarcinoma and large cell lung cancer than in squamous cell carcinoma? A retrospective analysis of a phase III trial of pemetrexed versus docetaxel in previously treated patients with advanced non-small cell lung cancer (NSCLC): P2-328. 12th World Conference on Lung Cancer; 2007 Sep 2-6; Seoul. J Thorac Oncol 2007 Aug; 2 (8 Suppl.): 851S
-
(2007)
12th World Conference on Lung Cancer
, vol.2
, Issue.8 SUPPL.
-
-
Peterson, P.1
Park, K.2
Fossella, F.V.3
-
38
-
-
22044445517
-
On behalf of the National Cancer Institute of Canada Clinical Trials Group. Erlotinib in previously treated non-small-cell lung cancer
-
Shepherd FA, Rodrigues Pereira J, Ciuleanu T, et al., on behalf of the National Cancer Institute of Canada Clinical Trials Group. Erlotinib in previously treated non-small-cell lung cancer. N Engl J Med 2005; 353 (2): 123-132
-
(2005)
N Engl J Med
, vol.353
, Issue.2
, pp. 123-132
-
-
Shepherd, F.A.1
Rodrigues Pereira, J.2
Ciuleanu, T.3
-
39
-
-
27544503230
-
Gefitinib plus best supportive care in previously treated patients with refractory advanced non-small-cell lung cancer: Results from a randomised, placebo-controlled, multicentre study (Iressa Survival Evaluation in Lung Cancer)
-
Thatcher N, Chang A, Parikh P, et al. Gefitinib plus best supportive care in previously treated patients with refractory advanced non-small-cell lung cancer: results from a randomised, placebo-controlled, multicentre study (Iressa Survival Evaluation in Lung Cancer). Lancet 2005; 366 (9496): 1527-1537
-
(2005)
Lancet
, vol.366
, Issue.9496
, pp. 1527-1537
-
-
Thatcher, N.1
Chang, A.2
Parikh, P.3
-
40
-
-
0012381722
-
Multi-institutional randomized phase II trial of gefitinib for previously treated patients with advanced non-small-cell lung cancer
-
Fukuoka M, Yano S, Giaccone G, et al. Multi-institutional randomized phase II trial of gefitinib for previously treated patients with advanced non-small-cell lung cancer. J Clin Oncol 2003; 21 (12): 2237-2246
-
(2003)
J Clin Oncol
, vol.21
, Issue.12
, pp. 2237-2246
-
-
Fukuoka, M.1
Yano, S.2
Giaccone, G.3
-
41
-
-
0142055937
-
Efficacy of gefitinib, an inhibitor of the epidermal growth factor receptor tyrosine kinase, in symptomatic patients with non-small cell lung cancer: A randomized trial
-
Kris MG, Natale RB, Herbst RS, et al. Efficacy of gefitinib, an inhibitor of the epidermal growth factor receptor tyrosine kinase, in symptomatic patients with non-small cell lung cancer: a randomized trial. JAMA 2003; (16): 2149-2158
-
(2003)
JAMA
, vol.16
, pp. 2149-2158
-
-
Kris, M.G.1
Natale, R.B.2
Herbst, R.S.3
-
42
-
-
56249109644
-
Gefitinib versus docetaxel in previously treated non-small-cell lung cancer (INTEREST): A randomized phase III trial
-
Kim ES, Hirsh V, Mok T, et al. Gefitinib versus docetaxel in previously treated non-small-cell lung cancer (INTEREST): a randomized phase III trial. Lancet 2008; 372: 1809-1818
-
(2008)
Lancet
, vol.372
, pp. 1809-1818
-
-
Kim, E.S.1
Hirsh, V.2
Mok, T.3
-
43
-
-
54249138858
-
Sorafenib plus carbo-platin/paclitaxel in chemonaive patients with stage IIB-IV non-small cell lung cancer (NSCLC): Interim analysis (IA) results from the phase III, randomized, double-blind, placebo-controlled ESCAPE (Evaluation of sorafenib, carboplatin, and paclitaxel efficacy in NSCLC) trial [abstract]
-
Scagliotti G, von Pawel J, Reck M. Sorafenib plus carbo-platin/paclitaxel in chemonaive patients with stage IIB-IV non-small cell lung cancer (NSCLC): interim analysis (IA) results from the phase III, randomized, double-blind, placebo-controlled ESCAPE (Evaluation of sorafenib, carboplatin, and paclitaxel efficacy in NSCLC) trial [abstract]. J Thorac Oncol 2008; 3 (4) Suppl. 1: 275O
-
(2008)
J Thorac Oncol
, vol.3-4
, Issue.SUPPL. 1
-
-
Scagliotti, G.1
Von Pawel, J.2
Reck, M.3
-
44
-
-
33645805630
-
Use of cigarette-smoking history to estimate the likelihood of mutations in epidermal growth factor receptor gene exons 19 and 21 in lung adeno-carcinomas
-
Pham D, Kris MG, Riely GJ, et al. Use of cigarette-smoking history to estimate the likelihood of mutations in epidermal growth factor receptor gene exons 19 and 21 in lung adeno-carcinomas. J Clin Oncol 2006; 24 (11): 1700-1704
-
(2006)
J Clin Oncol
, vol.24
, Issue.11
, pp. 1700-1704
-
-
Pham, D.1
Kris, M.G.2
Riely, G.J.3
-
45
-
-
33750205340
-
A phase II trial of gefitinib as first-line therapy for advanced non-small cell lung cancer with epidermal growth factor receptor mutations
-
Asahina H, Yamazaki K, Kinoshita I, et al. A phase II trial of gefitinib as first-line therapy for advanced non-small cell lung cancer with epidermal growth factor receptor mutations. Br J Cancer 2006; 95 (8): 998-1004
-
(2006)
Br J Cancer
, vol.95
, Issue.8
, pp. 998-1004
-
-
Asahina, H.1
Yamazaki, K.2
Kinoshita, I.3
-
46
-
-
33845262077
-
Gefitinib for non-small-cell lung cancer patients with epidermal growth factor receptor gene mutations screened by peptide nucleic acid-locked nucleic acid PCR clamp
-
Sutani A, Nagai Y, Udagawa K, et al. Gefitinib for non-small-cell lung cancer patients with epidermal growth factor receptor gene mutations screened by peptide nucleic acid-locked nucleic acid PCR clamp. Br J Cancer 2006; 95 (11): 1483-1489
-
(2006)
Br J Cancer
, vol.95
, Issue.11
, pp. 1483-1489
-
-
Sutani, A.1
Nagai, Y.2
Udagawa, K.3
-
47
-
-
33746789922
-
Prospective phase II study of gefitinib for chemotherapy-naive patients with advanced non-small-cell lung cancer with epidermal growth factor receptor gene mutations
-
Inoue A, Suzuki T, Fukuhara T, et al. Prospective phase II study of gefitinib for chemotherapy-naive patients with advanced non-small-cell lung cancer with epidermal growth factor receptor gene mutations. J Clin Oncol 2006; 24 (21): 3340-3346
-
(2006)
J Clin Oncol
, vol.24
, Issue.21
, pp. 3340-3346
-
-
Inoue, A.1
Suzuki, T.2
Fukuhara, T.3
-
48
-
-
34247619676
-
Phase II pro-spective study of the efficacy of gefitinib for the treatment of stage III/IV non-small cell lung cancer with EGFR mutations, irrespective of previous chemotherapy
-
Sunaga N, Tomizawa Y, Yanagitani N, et al. Phase II pro-spective study of the efficacy of gefitinib for the treatment of stage III/IV non-small cell lung cancer with EGFR mutations, irrespective of previous chemotherapy. Lung Cancer 2007; 56 (3): 383-389
-
(2007)
Lung Cancer
, vol.56
, Issue.3
, pp. 383-389
-
-
Sunaga, N.1
Tomizawa, Y.2
Yanagitani, N.3
-
49
-
-
33845434121
-
A pro-spective phase II trial of erlotinib in advanced non-small cell lung cancer (NSCLC) patients (p) with mutations in the tyrosine kinase (TK) domain of the epidermal growth factor receptor (EGFR) [abstract]
-
Paz-Ares L, Sanchez JM, Garcia-Velasco A, et al. A pro-spective phase II trial of erlotinib in advanced non-small cell lung cancer (NSCLC) patients (p) with mutations in the tyrosine kinase (TK) domain of the epidermal growth factor receptor (EGFR) [abstract]. J Clin Oncol 2006; 24: 7020
-
(2006)
J Clin Oncol
, vol.24
, pp. 7020
-
-
Paz-Ares, L.1
Sanchez, J.M.2
Garcia-Velasco, A.3
-
50
-
-
45149084723
-
First-line gefitinib in patients with advanced non-small-cell lung cancer harboring somatic EGFR mutations
-
Sequist LV, Martins RG, Spigel D, et al. First-line gefitinib in patients with advanced non-small-cell lung cancer harboring somatic EGFR mutations. J Clin Oncol 2008; 26 (15): 2442-2449
-
(2008)
J Clin Oncol
, vol.26
, Issue.15
, pp. 2442-2449
-
-
Sequist, L.V.1
Martins, R.G.2
Spigel, D.3
-
51
-
-
40349111048
-
Multicentre pro-spective phase II trial of gefitinib for advanced non-small cell lung cancer with epidermal growth factor receptor mutations: Results of the West Japan Thoracic Oncology Group trial (WJTOG0403)
-
Tamura K, Okamoto I, Kashii T, et al. Multicentre pro-spective phase II trial of gefitinib for advanced non-small cell lung cancer with epidermal growth factor receptor mutations: results of the West Japan Thoracic Oncology Group trial (WJTOG0403). Br J Cancer 2008; 98 (5): 907-914
-
(2008)
Br J Cancer
, vol.98
, Issue.5
, pp. 907-914
-
-
Tamura, K.1
Okamoto, I.2
Kashii, T.3
-
52
-
-
69949162760
-
Gefitinib or carbo-platin-paclitaxel in pulmonary adenocarcinoma
-
Mok T, Wu Y, Thongprasert S, et al. Gefitinib or carbo-platin-paclitaxel in pulmonary adenocarcinoma. N Engl J Med 2009; 361: 947-957
-
(2009)
N Engl J Med
, vol.361
, pp. 947-957
-
-
Mok, T.1
Wu, Y.2
Thongprasert, S.3
-
53
-
-
70350493524
-
First-line gefitinib versus first-line chemotherapy by carboplatin (CBDCA) plus paclitaxel (TXL) in non-small cell lung cancer (NSCLC) patients (pts) with EGFR mutations
-
Kobayashi K, Inoue A, Maemondo M, et al. First-line gefitinib versus first-line chemotherapy by carboplatin (CBDCA) plus paclitaxel (TXL) in non-small cell lung cancer (NSCLC) patients (pts) with EGFR mutations: a phase III study (002) by North East Japan Gefitinib Study Group [abstract]. J Clin Oncol 2009; 27: 8016
-
(2009)
J Clin Oncol
, vol.27
, pp. 8016
-
-
Kobayashi, K.1
Inoue, A.2
Maemondo, M.3
-
54
-
-
52049090365
-
Role of KRAS and EGFR as biomarkers of response to erlotinib in National Cancer Institute of Canada Clinical Trials Group Study BR.21
-
Zhu C, da Cunha Santos G, Ding K, et al. Role of KRAS and EGFR as biomarkers of response to erlotinib in National Cancer Institute of Canada Clinical Trials Group Study BR.21. J Clin Oncol 2008; 26: 4268-4275
-
(2008)
J Clin Oncol
, vol.26
, pp. 4268-4275
-
-
Zhu, C.1
Da Cunha Santos, G.2
Ding, K.3
-
55
-
-
33750962024
-
Molecular pre-dictors of outcome with gefitinib in a phase III placebo-controlled study in advanced non-small-cell lung cancer
-
Hirsch F, Varella-Garcia M, Bunn P, et al. Molecular pre-dictors of outcome with gefitinib in a phase III placebo-controlled study in advanced non-small-cell lung cancer. J Clin Oncol 2006; 24: 5034-5042
-
(2006)
J Clin Oncol
, vol.24
, pp. 5034-5042
-
-
Hirsch, F.1
Varella-Garcia, M.2
Bunn, P.3
-
56
-
-
70349720358
-
Biomarker ana-lyses from a phase III, randomized, open-label, first-line study of gefitinib (G) versus carboplatin/paclitaxel (C/P) in clinically selected patients (pts) with advanced non-small cell lung cancer (NSCLC) in Asia (IPASS) [abstract]
-
Fukuoka M, Wu Y, Thongprasert S, et al. Biomarker ana-lyses from a phase III, randomized, open-label, first-line study of gefitinib (G) versus carboplatin/paclitaxel (C/P) in clinically selected patients (pts) with advanced non-small cell lung cancer (NSCLC) in Asia (IPASS) [abstract]. J Clin Oncol (Meeting Abstracts) 2009; 27: 8006
-
(2009)
J Clin Oncol (Meeting Abstracts)
, vol.27
, pp. 8006
-
-
Fukuoka, M.1
Wu, Y.2
Thongprasert, S.3
-
58
-
-
49149127726
-
Increased EGFR gene copy number detected by fluorescent in situ hybridization predicts outcome in non-small cell lung cancer patients treated with cetuximab and chemotherapy
-
Hirsch FR, Herbst RS, Olsen C, et al. Increased EGFR gene copy number detected by fluorescent in situ hybridization predicts outcome in non-small cell lung cancer patients treated with cetuximab and chemotherapy. J Clin Oncol 2008; 26 (20): 3351-3357
-
(2008)
J Clin Oncol
, vol.26
, Issue.20
, pp. 3351-3357
-
-
Hirsch, F.R.1
Herbst, R.S.2
Olsen, C.3
-
59
-
-
33847662996
-
Epidermal growth factor receptor gene copy number and protein level are not associated with outcome of non-small-cell lung cancer patients treated with chemotherapy
-
Dziadziuszko R, Holm B, Skov BG, et al. Epidermal growth factor receptor gene copy number and protein level are not associated with outcome of non-small-cell lung cancer patients treated with chemotherapy. Ann Oncol 2007; 18: 447-452
-
(2007)
Ann Oncol
, vol.18
, pp. 447-452
-
-
Dziadziuszko, R.1
Holm, B.2
Skov, B.G.3
-
60
-
-
0142119289
-
Epidermal growth factor receptor in non-small-cell lung carcinomas: Correlation between gene copy number and protein expression and impact on prognosis
-
Hirsch FR, Varella-Garcia M, Bunn Jr PA, et al. Epidermal growth factor receptor in non-small-cell lung carcinomas: correlation between gene copy number and protein expression and impact on prognosis. J Clin Oncol 2003; 21: 3798-3807
-
(2003)
J Clin Oncol
, vol.21
, pp. 3798-3807
-
-
Hirsch, F.R.1
Varella-Garcia, M.2
Bunn Jr, P.A.3
-
61
-
-
68949124435
-
Molecular and clinical predictors of outcome for cetuximab in non-small cell lung cancer (NSCLC): Data from the FLEX study [abstract]
-
O'Byrne KJ, Bondarenko I, Barrios C, et al. Molecular and clinical predictors of outcome for cetuximab in non-small cell lung cancer (NSCLC): data from the FLEX study [abstract]. J Clin Oncol 2009; 27: 8007
-
(2009)
J Clin Oncol
, vol.27
, pp. 8007
-
-
O'Byrne, K.J.1
Bondarenko, I.2
Barrios, C.3
-
62
-
-
76149126918
-
K-Ras mutation (mut), EGFR-related, and exploratory markers as response predictors of cetuximab in first-line advanced NSCLC: Retrospective analyses of the BMS099 trial [abstract]
-
Khambata-Ford S, Harbison C, Woytowitz D, et al. K-Ras mutation (mut), EGFR-related, and exploratory markers as response predictors of cetuximab in first-line advanced NSCLC: retrospective analyses of the BMS099 trial [abstract]. J Clin Oncol 2009; 27: 8021
-
(2009)
J Clin Oncol
, vol.27
, pp. 8021
-
-
Khambata-Ford, S.1
Harbison, C.2
Woytowitz, D.3
-
64
-
-
65349107082
-
KRAS mutations in non-small cell lung cancer
-
Reily GJ, Marks J, Pao W. KRAS mutations in non-small cell lung cancer. Proc Am Thorac Soc 2009; 6 (2): 201-205
-
(2009)
Proc Am Thorac Soc
, vol.6
, Issue.2
, pp. 201-205
-
-
Reily, G.J.1
Marks, J.2
Pao, W.3
-
65
-
-
34249810645
-
KRAS mu-tation is an important predictor of resistance to therapy with epidermal growth factor receptor tyrosine kinase inhibitors in non-small-cell lung cancer
-
Massarelli E, Varella-Garcia M, Tang X, et al. KRAS mu-tation is an important predictor of resistance to therapy with epidermal growth factor receptor tyrosine kinase inhibitors in non-small-cell lung cancer. Clin Cancer Res 2007; 13: 2890-2896
-
(2007)
Clin Cancer Res
, vol.13
, pp. 2890-2896
-
-
Massarelli, E.1
Varella-Garcia, M.2
Tang, X.3
-
66
-
-
70349476965
-
Bio-marker analyses from the phase III placebo-controlled SATURN study of maintenance erlotinib following first-line chemotherapy for advanced NSCLC [abstract]
-
Brugger W, Triller N, Blasinska-Morawiec M, et al. Bio-marker analyses from the phase III placebo-controlled SATURN study of maintenance erlotinib following first-line chemotherapy for advanced NSCLC [abstract]. J Clin Oncol 2009; 27: 8020
-
(2009)
J Clin Oncol
, vol.27
, pp. 8020
-
-
Brugger, W.1
Triller, N.2
Blasinska-Morawiec, M.3
-
67
-
-
54949085398
-
K-ras mutations and benefit from cetuximab in advanced colo-rectal cancer
-
Karapetis CS, Khambata-Ford S, Jonker DJ, et al. K-ras mutations and benefit from cetuximab in advanced colo-rectal cancer. N Engl J Med 2008; 359 (17): 1757-1765
-
(2008)
N Engl J Med
, vol.359
, Issue.17
, pp. 1757-1765
-
-
Karapetis, C.S.1
Khambata-Ford, S.2
Jonker, D.J.3
-
68
-
-
0035988959
-
Low ERCC1 ex-pression correlates with prolonged survival after cisplatin plus gemcitabine chemotherapy in non-small cell lung cancer
-
Lord RV, Brabender J, Gandara D, et al. Low ERCC1 ex-pression correlates with prolonged survival after cisplatin plus gemcitabine chemotherapy in non-small cell lung cancer. Clin Cancer Res 2002; 8 (7): 2286-2291
-
(2002)
Clin Cancer Res
, vol.8
, Issue.7
, pp. 2286-2291
-
-
Lord, R.V.1
Brabender, J.2
Gandara, D.3
-
69
-
-
33748435058
-
DNA repair by ERCC1 in non-small-cell lung cancer and cisplatin-based adjuvant chemotherapy
-
Olaussen KA, Dunant A, Fouret P, et al. DNA repair by ERCC1 in non-small-cell lung cancer and cisplatin-based adjuvant chemotherapy. N Engl J Med 2006; 355 (10): 983-991
-
(2006)
N Engl J Med
, vol.355
, Issue.10
, pp. 983-991
-
-
Olaussen, K.A.1
Dunant, A.2
Fouret, P.3
-
70
-
-
34447573875
-
Customizing cisplatin based on quantitative excision repair cross-complementing 1 mRNA expression: A phase III trial in non-small cell lung cancer
-
Cobo M, Isla D, Massuti B, et al. Customizing cisplatin based on quantitative excision repair cross-complementing 1 mRNA expression: a phase III trial in non-small cell lung cancer. J Clin Oncol 2007; 25 (19): 2747-2754
-
(2007)
J Clin Oncol
, vol.25
, Issue.19
, pp. 2747-2754
-
-
Cobo, M.1
Isla, D.2
Massuti, B.3
-
71
-
-
2542530631
-
An increase in the expression of ribonucleotide reductase large subunit 1 is associated with gemcitabine resistance in non-small cell lung cancer cell lines
-
Davidson JD, Ma L, Flagella M, et al. An increase in the expression of ribonucleotide reductase large subunit 1 is associated with gemcitabine resistance in non-small cell lung cancer cell lines. Cancer Res 2004; 64 (11): 3761-3766
-
(2004)
Cancer Res
, vol.64
, Issue.11
, pp. 3761-3766
-
-
Davidson, J.D.1
Ma, L.2
Flagella, M.3
-
72
-
-
33750579074
-
RRM1 modulated in vitro and in vivo efficacy of gemcitabine and platinum in non-small-cell lung cancer
-
Bepler G, Kusmartseva I, Sharma S, et al. RRM1 modulated in vitro and in vivo efficacy of gemcitabine and platinum in non-small-cell lung cancer. J Clin Oncol 2006; 24 (29): 4731-4737
-
(2006)
J Clin Oncol
, vol.24
, Issue.29
, pp. 4731-4737
-
-
Bepler, G.1
Kusmartseva, I.2
Sharma, S.3
-
73
-
-
34447567414
-
Feasibility and efficacy of molecular analysis-directed individualized therapy in advanced non-small-cell lung cancer
-
Simon G, Sharma A, Li X, et al. Feasibility and efficacy of molecular analysis-directed individualized therapy in advanced non-small-cell lung cancer. J Clin Oncol 2007; 25: 2741-2746
-
(2007)
J Clin Oncol
, vol.25
, pp. 2741-2746
-
-
Simon, G.1
Sharma, A.2
Li, X.3
-
75
-
-
0031035052
-
Molecular character-ization of ALK, a receptor tyrosine kinase expressed specifically in the nervous system
-
Iwahara T, Fujimoto J, Wen D, et al. Molecular character-ization of ALK, a receptor tyrosine kinase expressed specifically in the nervous system. Oncogene 1997; 14: 439-449
-
(1997)
Oncogene
, vol.14
, pp. 439-449
-
-
Iwahara, T.1
Fujimoto, J.2
Wen, D.3
-
76
-
-
0028198206
-
Fusion of a kinase gene, ALK, to a nucleolar protein gene, NPM, in non-Hodgkin's lymphoma
-
Morris SW, Kirstein MN, Valentine MB, et al. Fusion of a kinase gene, ALK, to a nucleolar protein gene, NPM, in non-Hodgkin's lymphoma. Science 1994; 263: 1281-1287
-
(1994)
Science
, vol.263
, pp. 1281-1287
-
-
Morris, S.W.1
Kirstein, M.N.2
Valentine, M.B.3
-
77
-
-
34547638047
-
Identification of the transforming EML4-ALK fusion gene in non-small-cell lung cancer
-
Soda M, Choi YL, Enomoto M, et al. Identification of the transforming EML4-ALK fusion gene in non-small-cell lung cancer. Nature 2007; 448: 561-566
-
(2007)
Nature
, vol.448
, pp. 561-566
-
-
Soda, M.1
Choi, Y.L.2
Enomoto, M.3
-
78
-
-
70349336416
-
Clinical features and outcome of patients with non-small-cell lung cancer harboring EML4-ALK
-
Shaw AT, Yeap BY, Mino-Kenudson M, et al. Clinical features and outcome of patients with non-small-cell lung cancer harboring EML4-ALK. J Clin Oncol 2009; 27: 4247-4253
-
(2009)
J Clin Oncol
, vol.27
, pp. 4247-4253
-
-
Shaw, A.T.1
Yeap, B.Y.2
Mino-Kenudson, M.3
-
79
-
-
75749088881
-
Clinical activity of the oral ALK and MET inhibitor PF-02341066 in non-small lung cancer (NSCLC) with EML4-ALK transloca-tions [abstract]
-
A6.4
-
Shaw AT, Costa DB, Iafrate AJ, et al. Clinical activity of the oral ALK and MET inhibitor PF-02341066 in non-small lung cancer (NSCLC) with EML4-ALK transloca-tions [abstract]. J Thorac Oncol 2009; 4 Suppl. 1: S305 (A6.4)
-
(2009)
J Thorac Oncol
, vol.4
, Issue.SUPPL.1
-
-
Shaw, A.T.1
Costa, D.B.2
Iafrate, A.J.3
-
80
-
-
75749143039
-
-
Pfizer An investigational drug, PF-02341066 is being stu-died versus standard of care in patients with advanced non-small cell lung cancer with a specific gene profile involving the anaplastic lymphoma kinase (ALK) gene [ClinicalTrials. gov identifier NCT00660816]. US National Institutes of Health, ClinicalTrials.gov [online] [Accessed 2009 Dec 24]
-
Pfizer. An investigational drug, PF-02341066 is being stu-died versus standard of care in patients with advanced non-small cell lung cancer with a specific gene profile involving the anaplastic lymphoma kinase (ALK) gene [ClinicalTrials. gov identifier NCT00660816]. US National Institutes of Health, ClinicalTrials.gov [online]. Available from URL: http://clinicaltrials.gov/ct2/ show/NCT00932893?term=NCT00932893&rank=1 [Accessed 2009 Dec 24]
-
-
-
-
81
-
-
70350225538
-
Maintenance pemetrexed plus best supportive care versus placebo plus best supportive care for non-small-cell lung cancer: A randomised, double-blind, phase 3 study
-
Ciuleanu T, T Brodowicz T, Zielinski C, et al. Maintenance pemetrexed plus best supportive care versus placebo plus best supportive care for non-small-cell lung cancer: a randomised, double-blind, phase 3 study. Lancet 2009; 374 (9699): 1432-1440
-
(2009)
Lancet
, vol.374
, Issue.9699
, pp. 1432-1440
-
-
Ciuleanu, T.1
Brodowicz T, T.2
Zielinski, C.3
-
82
-
-
33749587054
-
Squamous cell carci-noma of the lung compared with other histotypes shows higher messenger RNA and protein levels for thymidylate synthase
-
Ceppi P, Volante M, Saviozzi S, et al. Squamous cell carci-noma of the lung compared with other histotypes shows higher messenger RNA and protein levels for thymidylate synthase. Cancer 2006; 107 (7): 1589-1596
-
(2006)
Cancer
, vol.107
, Issue.7
, pp. 1589-1596
-
-
Ceppi, P.1
Volante, M.2
Saviozzi, S.3
-
83
-
-
0041695633
-
Induction of resistance to the multitargeted antifolate pemetrexed (ALIMTA) in WiDr human colon cancer cells is associated with thymidylate synthase overexpression
-
Sigmond J, Backus HHJ, Wouters D, et al. Induction of resistance to the multitargeted antifolate pemetrexed (ALIMTA) in WiDr human colon cancer cells is associated with thymidylate synthase overexpression. Biochem Pharmacol 2003; 66 (3): 431-8 84.
-
(2003)
Biochem Pharmacol
, vol.66
, Issue.3
, pp. 431-884
-
-
Sigmond, J.1
Backus, H.H.J.2
Wouters, D.3
-
84
-
-
22344449812
-
Cellular and pharmacogenetics foundation of synergistic interaction of pemetrexed and gemcitabine in human non-small-cell lung cancer cells
-
DOI 10.1124/mol.104.009373
-
Giovannetti E, Mey V, Nannizzi S, et al. Cellular and pharmacogenetics foundation of synergistic interaction of pemetrexed and gemcitabine in human non-small-cell lung cancer cells. Mol Pharmacol 2005; 68 (1): 110-118 (Pubitemid 41002949)
-
(2005)
Molecular Pharmacology
, vol.68
, Issue.1
, pp. 110-118
-
-
Giovannetti, E.1
Mey, V.2
Nannizzi, S.3
Pasqualetti, G.4
Marini, L.5
Del Tacca, M.6
Danesi, R.7
|