Vitamin D receptor gene polymorphisms in Indian children with idiopathic nephrotic syndrome

International Journal of Human Genetics

Volumn 9, Issue 1, 2009, Pages 49-55

  Jafar, Tabrez ^a   Tripathi, Gaurav ^a   Mehndi, Abass A ^b   Mandal, Kaushik ^a   Gulati, Sanjeev ^a   Sharma, Raj K ^a   Baburaj, Vinod P ^a   Awasthi, Shaily ^b   Agrawal, Suraksha ^a  

^a SANJAY GANDHI POSTGRADUATE INSTITUTE OF MEDICAL SCIENCES   (India)

^b KING GEORGE'S MEDICAL UNIVERSITY   (India)

Author keywords

Idiopathic Nephrotic syndrome (INS); PCR RFLP; Polymorphism; Vitamin D Receptor (VDR)

Indexed keywords

VITAMIN D RECEPTOR;

ARTICLE; CHILD; CONTROLLED STUDY; DNA POLYMORPHISM; FEMALE; GENE FREQUENCY; GENE FUNCTION; GENETIC PREDISPOSITION; GENOTYPE; HIGH RISK PATIENT; HUMAN; INDIA; MAJOR CLINICAL STUDY; MALE; METABOLIC BONE DISEASE; NEPHROTIC SYNDROME; POLYMERASE CHAIN REACTION;

EID: 75749132078     PISSN: 09723757     EISSN: None     Source Type: Journal    
DOI: 10.1080/09723757.2009.11886060     Document Type: Article

References (26)

1. Alroy I, Towres TL, Freedman LP 1995. Transcriptional repression of the interleukin-2 gene by Vitamin D3: Direct inhibition of NFATp/AP complex formation by a nuclear hormone receptor. Mol. Cell Biol, 15: 5789-5799.
2. Beato M 1989. Gene regulation by steroid hormone. Cell, 56: 335-344.
3. Farrow S 1994. Allelic variation and the vitamin D receptor. Lancet,. 21;343(8908): 1242.
4. Gulati S, Godbole M, Singh U, Gulati K, Srivastava A 2003. Are children with idiopathic nephrotic syndrome at risk for metabolic bone disease? Am J Kidney Dis, 41: 1163-1169.
5. Gulati S, Kher V, Elhence R, Kumar P, Sharma RK, Gupta A 1994. Treatment of nephrotic syndrome. Ind Pediatr, 31: 165-170.
6. Haussler MR, Whitfield GK, Haussler CA, Hsieh JC, Thompsom PD, Selznick SH, Encinas-Domingeuz C, Jurutka PW 1998. The nuclear vitamin D receptor biological and molecular regulatory properties revealed. J of Bone and Min Res, 13: 325-349.
7. Holick MF 2004. Vitamin D Importance in the prevention of cancers, type 1 diabetes, heart disease, and osteoporosis. Am J Clin Nutr, 79: 362-371.
8. Klein GL, Herndon DN, Rutan TC, Sherrard DJ, Coburn JW, Langman CB, Thomas ML, Haddad JG Jr, Cooper CW, Miller NL 1993. Bone disease in burn patients. J Bone Miner Res, 8(3): 337-45.
9. Lemire JM, Archer DC, Beck L, Spiegeburg HL 1995. Immunosuppressive actions of 1, 25-Dihydroxyvitamin D3: Preferential inhibition of Th1 functions. J Nutr, 125: 1704S-1708S.
10. McDermott MF, Ramachandran A, Ogunkolade BW 1997. Allelic variation in the vitamin D receptor influences susceptibility to IDDM in Indian Asians. Diabetologia, 40: 971-975.
11. Mitra S, Desai M, Ikram Khatkhatay M 2006. Vitamin D receptor gene polymorphisms and bone mineral density in postmenopausal Indian women. Maturitas, 20: 55(1): 27-35.
12. Mittal RD, Manchanda PK, Bhat S, Bid HK 2007. Association of vitamin-D receptor (Fok-I) gene polymorphism with bladder cancer in an Indian population. BJU Int, 99(4): 933-937.
13. Morrison NA,Qi JC, Tokita A, Kelly PJ,Crotis L, Nguyen TV, Sambrook PN, Eisman JA 1994. Prediction of bone density from vitamin D receptor alleles. Nature, 367: 284-287.
14. Mosmann TR, Coffman RL 1989. TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties. Annu Rev Immunol, 7: 145-173
15. Nesic D, Cheng J, Maquat LE 1993. Sequences within the last intron function in RNA 3'-end formation in cultured cells. Mol Cell Biol, 13(6): 3359-69.
16. Oh JY, Barrett-Connor E 2002. Association between vitamin D receptor polymorphism and type 2 diabetes or metabolic syndrome in communitydwelling older adults: the Rancho Bernardo Study. Metabolism, 51: 356-359.
17. Ozaki Y, Nomura S, Nagahama M, Yoshimura C, Kagawa H, Fukuhara S 2000. Vitamin-D receptor genotype and renal disorder in Japanese patients with systemic lupus erythematosus Nephron, 85(1): 86-91.
18. Peacock M, Turner CH, Econs MJ, Foroud T 2002. Genetics of osteoporosis. Endocr Rev, 23: 303-326.
19. Saijo T, Ito M, Takeda E, Huq AH, Naito E, Yokota I, Sone T, Pike JW, Kuroda YA 1991. Unique mutation in the vitamin D receptor gene in three Japanese patients with vitamin D-dependent rickets type II: utility of single-strand conformation polymorphism analysis for heterozygous carrier detection. Am J Hum Genet, Sep49(3): 668-73.
20. Sainz J, VanTornout JM, Loro ML, Sayre J,Roe TP,Gilsanz 1997. Vitamin D receptor gene polymorphism and bone density in prepubertal American girls of Mexican descent. N Engl J Med, 337: 77-82.
21. Selvaraj P, Alagarasu K, Harishankar M, Vidyarani M, Narayanan PR 2008. Regulatory region polymorphisms of vitamin D receptor gene in pulmonary tuberculosis patients and normal healthy subjects of south India. Int J Immunogenet, 35(3): 251-254.
22. Shaffer PL, Gewirth DT 2004. Structural analysis of RXR-VDR interactions on DR3 DNAJ Steroid Biochem Mol Biol, 89-90(1-5): 215-9.
23. Shimoyama H, Nakajima M, Naka H, Maruhashi Y, Akazawa H, Ueda T, Nishiguchi M, Yamoto Y, Kamitsuji H, Yoshioka A 2004. Up-regulation of interleukin-2 mRNA in children with idiopathic nephrotic syndrome. Pediatr Nephrol, 19(10): 1115-21.
24. Topaloglu R, Saatei U,Arikan M, Canpiner H,Bakkaloglu A, Kansu E 1994. t- cell subsets, interleukin-2 receptor expression and production of interleukin 2 in minimal change nephritic syndrome. Pediatr Nephrol, 8: 649-652.
25. Van Schooten FJ, Hirvonen A, Maas LM, De Mol BA, Kleinjans JCS, Bell DA, et al 1998. Putative susceptibility markers of coronary artery disease: association between VDR genotype, smoking, and aromatic DNA adduct level in human right atrial tissue. FASEB J, 12: 1409-17.
26. Vupputuri MR, Goswami R, Gupta N, Ray D, Tandon N, Kumar N 2006. Prevalence and functional significance of 25-hydroxyvitamin D deficiency and vitamin D receptor gene polymorphisms in Asian Indians. Am J Clin Nutr, 83(6): 1411-9.