Extracellular production of an RNA aptamer by ribonuclease-free marine bacteria harboring engineered plasmids: A proposal for industrial RNA drug production

Applied and Environmental Microbiology

Volumn 76, Issue 3, 2010, Pages 786-793

  Suzuki, Hiromichi ^a   Ando, Tomoaki ^a,b   Umekage, So ^a   Tanaka, Terumichi ^a   Kikuchi, Yo ^a  

^a TOYOHASHI UNIVERSITY OF TECHNOLOGY   (Japan)

^b Sannomiya Plaza Bldg   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

APTAMERS; ARTIFICIAL RNA; CELLULAR PROCESS; CULTIVATION PERIODS; CULTURE MEDIUM; CURRENT TECHNIQUES; DRUG PRODUCTION; EXTRACELLULAR; IN-VIVO; INDUSTRIAL PRODUCTION; MARINE BACTERIUM; PHOTOTROPHIC BACTERIUM; RIBOZYMES; RNA APTAMER; SMALL INTERFERING RNA; SMALL RNA; STREPTAVIDIN; THERAPEUTIC AGENTS;

BACTERIA; MARINE ENGINEERING; NUCLEIC ACIDS;

RNA;

APTAMER; BACTERIAL DNA; RIBONUCLEASE; RIBOZYME; RNA; RNA 16S; STREPTAVIDIN;

BACTERIUM; DEGRADATION; ENZYME ACTIVITY; PLASMID; RNA;

ARTICLE; BIOSYNTHESIS; CONFORMATION; CULTURE MEDIUM; ENZYMOLOGY; GENETIC ENGINEERING; GENETICS; METABOLISM; MICROBIOLOGY; MOLECULAR CLONING; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PLASMID; RHODOVULUM; SEQUENCE ANALYSIS;

APTAMERS, NUCLEOTIDE; BASE SEQUENCE; CLONING, MOLECULAR; CULTURE MEDIA; DNA, BACTERIAL; ENDORIBONUCLEASES; GENETIC ENGINEERING; INDUSTRIAL MICROBIOLOGY; MOLECULAR SEQUENCE DATA; NUCLEIC ACID CONFORMATION; PLASMIDS; RHODOVULUM; RIBONUCLEASES; RNA; RNA, CATALYTIC; RNA, RIBOSOMAL, 16S; SEQUENCE ANALYSIS, RNA; STREPTAVIDIN; WATER MICROBIOLOGY;

BACTERIA (MICROORGANISMS); PHOTOBACTERIA; RHODOVULUM; RHODOVULUM SULFIDOPHILUM;

EID: 75749132001     PISSN: 00992240     EISSN: 10985336     Source Type: Journal    
DOI: 10.1128/AEM.01971-09     Document Type: Article

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