Phynx: An open source software solution supporting data management and web-based patient-level data review for drug safety studies in the general practice research database and other health care databases

Pharmacoepidemiology and Drug Safety

Volumn 19, Issue 1, 2010, Pages 38-44

  Egbring, Marco ^a   Kullak Ublick, Gerd A ^a   Russmann, Stefan ^a  

^a UNIVERSITY HOSPITAL ZURICH   (Switzerland)

Author keywords

Adobe flex 3; Apache tomcat; Claims databases; Eclipse; Electronic medical records; General practice research database (GPRD); Internet; Java; MySQL; Pharmacoepidemiology; Talend open studio; Validation

Indexed keywords

ARTICLE; CHRONOLOGY; COMPUTER PROGRAM; CONTROLLED STUDY; DATA BASE; DRUG SAFETY; ECONOMIC ASPECT; ELECTRONIC MEDICAL RECORD; FEMALE; GENERAL PRACTICE; HEALTH CARE; HUMAN; INFORMATION PROCESSING; INTERNET; MALE; OUTCOME ASSESSMENT; PATIENT CODING; PATIENT INFORMATION; PRESCRIPTION; PRIORITY JOURNAL; UNITED KINGDOM; VALIDITY;

CLINICAL LABORATORY INFORMATION SYSTEMS; DATABASE MANAGEMENT SYSTEMS; DATABASES, FACTUAL; DRUG TOXICITY; HUMANS; INTERNET; MEDICAL RECORDS SYSTEMS, COMPUTERIZED; PHARMACOEPIDEMIOLOGY;

EID: 75749128999     PISSN: 10538569     EISSN: 10991557     Source Type: Journal    
DOI: 10.1002/pds.1860     Document Type: Article

References (24)

1. Suissa S, Garbe E. Primer: administrative health databases in observational studies of drug effects-advantages and disadvantages. Nat Clin Pract Rheumatol 2007; 3: 725-732.
2. Schneeweiss S, Avorn J. A review of uses of health care utilization databases for epidemiologic research on therapeutics. J Clin Epidemiol 2005; 58: 323-337.
3. Hammad TA, McAdams MA, Feight A, Iyasu S, Dal Pan GJ. Determining the predictive value of Read/OXMIS codes to identify incident acute myocardial infarction in the General Practice Research Database. Pharmacoepidemiol Drug Saf 2008; 17: 1197-1201.
4. Katz JN, Barrett J, Liang MH, et al. Sensitivity and positive predictive value of Medicare Part B physician claims for rheumatologic diagnoses and procedures. Arthritis Rheum 1997; 40: 1594-1600.
5. Kiyota Y, Schneeweiss S, Glynn RJ, Cannuscio CC, Avorn J, Solomon DH. Accuracy of Medicare claims-based diagnosis of acute myocardial infarction: estimating positive predictive value on the basis of review of hospital records. Am Heart J 2004; 148: 99-104.
6. Wurst KE, Ephross SA, Loehr J, Clark DW, Guess HA. The utility of the general practice research database to examine selected congenital heart defects: a validation study. Pharmacoepidemiol Drug Saf 2007; 16: 867-877.
7. Russmann S, Lamerato L, Motsko SP, Pezzullo JC, Faber MD, Jones JK. Risk of further decline in renal function after the use of oral sodium phosphate or polyethylene glycol in patients with a preexisting glomerular filtration rate below 60 ml/min. Am J Gastroenterol 2008; 103: 2707-2716.
8. GPRD. http://www.gprd.com.
9. Walley T, Mantgani A. The UK General Practice Research Database. Lancet 1997; 350: 1097-1099.
10. Amazon Elastic Compute Cloud. http://aws.amazon.com/ec2
11. Apache Tomcat. http://tomcat.apache.org
12. Java SE. http://java.sun.com/javase
13. MySQL. http://dev.mysql.com
14. Eclipse. http://www.eclipse.org
15. Adobe Flex 3. http://www.adobe.com/products/flex
16. Talend Open Studio. http://www.talend.com/products-data-integration/ talend-open-studio.php.
17. PharMetrics. http://www.pharmetrics.com.
18. Voorham J, Denig P. Computerized extraction of information on the quality of diabetes care from free text in electronic patient records of general practitioners. J Am Med Inform Assoc 2007; 14: 349-354.
19. Jick H, Jick SS, Derby LE. Validation of information recorded on general practitioner based computerised data resource in the United Kingdom. BMJ 1991; 302: 766-768.
20. Jick SS, Kaye JA, Vasilakis-Scaramozza C, et al. Validity of the general practice research database. Pharmacotherapy 2003; 23: 686-689.
21. Andersohn F, Schade R, Suissa S, Garbe E. Cyclooxygenase-2 selective nonsteroidal anti-inflammatory drugs and the risk of ischemic stroke: a nested case-control study. Stroke 2006; 37: 1725-1730.
22. Jick H, Kaye JA, Russmann S, Jick SS. Nonsteroidal antiinflammatory drugs and acute myocardial infarction in patients with no major risk factors. Pharmacotherapy 2006; 26: 1379-1387.
23. Jick SS, Kaye JA, Russmann S, Jick H. Risk of nonfatal venous thromboembolism with oral contraceptives containing norgestimate or desogestrel compared with oral contraceptives containing levonorgestrel. Contraception 2006; 73: 566-570.
24. Meier CR, Jick SS, Derby LE, Vasilakis C, Jick H. Acute respiratory-tract infections and risk of first-time acute myocardial infarction. Lancet 1998; 351: 1467-1471.