Correlations between in vivo 1H MRS and ex vivo 1H HRMAS metabolite measurements in adult human gliomas

Journal of Magnetic Resonance Imaging

Volumn 31, Issue 2, 2010, Pages 289-297

  Opstad, Kirstie S ^a   Wright, Alan J ^a   Bell, B Anthony ^a   Griffiths, John R ^b   Howe, Franklyn A ^a  

^a ST GEORGE'S UNIVERSITY OF LONDON   (United Kingdom)

^b CANCER RESEARCH UK CAMBRIDGE RESEARCH INSTITUTE   (United Kingdom)

Author keywords

1H MRS; Astrocytoma; Biopsy; Magic angle spinning (MAS); Tumor

Indexed keywords

ALANINE; CHOLINE; CREATININE; GLUCOSE; GLUTAMIC ACID; GLUTAMINE; GLUTATHIONE; GLYCEROPHOSPHORYLCHOLINE; INOSITOL; INOSITOL DERIVATIVE; LACTIC ACID; LIPID; N ACETYLASPARTIC ACID; PHOSPHORYLCHOLINE; SCYLLOINOSITOL; TAURINE; UNCLASSIFIED DRUG;

ADULT; ANAEROBIC GLYCOLYSIS; ARTICLE; ASTROCYTOMA; BRAIN BIOPSY; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; DIAGNOSTIC ACCURACY; GLIOBLASTOMA; HIGH RESOLUTION MAGIC ANGLE SPINNING PROTON NUCLEAR MAGNETIC RESONANCE; HISTOGRAM; HUMAN; HUMAN TISSUE; METABOLITE; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; TUMOR BIOPSY;

ALGORITHMS; ASTROCYTOMA; BRAIN NEOPLASMS; DIAGNOSIS, COMPUTER-ASSISTED; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; PROTONS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; STATISTICS AS TOPIC; TUMOR MARKERS, BIOLOGICAL;

EID: 75749128255     PISSN: 10531807     EISSN: 15222586     Source Type: Journal    
DOI: 10.1002/jmri.22039     Document Type: Article

References (44)

1. Abrey LE, Mason WP. Brain tumours. London: Health Press; 2003.
2. Thorsen F, Tysnes BB. Brain tumor cell invasion, anatomical and biological considerations. Anticancer Res 1997;17:4121-4126.
3. 1H-MRS in vivo predicts the early treatment outcome of postoperative radiotherapy for malignant gliomas. Int J Radiat Oncol Biol Phys 2002;52: 1271-1276.
4. 1H MRSI parameters that may predict survival for patients with malignant gliomas. NMR Biomed 2004;17:10-20.
5. McKnight TR. Proton magnetic resonance spectroscopic evaluation of brain tumor metabolism. Semin Oncol 2004;31:605-617.
6. Tait MJ, Petrik V, Loosemore A, Bell BA, Papadopoulos MC. Survival of patients with glioblastoma multiforme has not improved between 1993 and 2004: analysis of 625 cases. Br J Neurosurg 2007;21:496-500.
7. Hoelzinger DB, Mariani L, Weis J, et al. Gene expression profile of glioblastoma multiforme invasive phenotype points to new therapeutic targets. Neoplasia 2005;7:7-16.
8. Whittle IR, Short DM, Deighton RF, Kerr LE, Smith C, McCulloch J. Proteomic analysis of gliomas. Br J Neurosurg 2007;21: 576-582.
9. Nakada M, Nakada S, Demuth T, Tran NL, Hoelzinger DB, Berens ME. Molecular targets of glioma invasion. Cell Mol Life Sci 2007; 64:458-478.
10. Wu CL, Taylor JL, He W, et al. Proton high-resolution magic angle spinning NMR analysis of fresh and previously frozen tissue of human prostate. Magn Reson Med 2003;50: 1307-1311.
11. 1H MRS and histological analysis. NMR Biomed 2008;21: 677-685.
12. 1H MR spectroscopy for assessment of apoptosis in cervical carcinomas. BMC Cancer 2007:17:7-11.
13. Tzika AA, Astrakas L, Cao H, et al. Combination of high-resolution magic angle spinning proton magnetic resonance spectroscopy and microscale genomics to type brain tumor biopsies. Int J Mol Med 2007;20:199-208.
14. 1H HR-MAS for childhood brain tumours. NMR Biomed 2009:22:213-219.
15. Webb PG, Sailasuta N, Kohler SJ, Raidy T, Moats RA, Hurd RE. Automated single-voxel proton MRS: technical development and multisite verification. Magn Reson Med 1994;31:365-373.
16. Provencher SW. Estimation of metabolite concentrations from localized in vivo proton NMR spectra. Magn Reson Med 1993;30: 672-679.
17. 1H spectroscopy. J Magn Reson Imaging 2004; 20:187-192.
18. Opstad KS, Bell BA, Griffiths JR, Howe FA. Towards accurate quantification of metabolites, lipids and macromolecules in HRMAS spectra of human brain tumor biopsies using LCModel. Magn Reson Med 2008:60:1237-142.
19. 1H NMR spectroscopy in vivo and in vitro. J Neurochem 1994;63: 1538-1543.
20. Cheng LL, Chang IW, Louis DN, Gonzalez RG. Correlation of high-resolution magic angle spinning proton magnetic resonance spectroscopy with histopathology of intact human brain tumor specimens. Cancer Res 1998;58:1825-1832.
21. Holm S. A simple sequentially rejective multiple test procedure. Scand J Stat 1979;6:65-70.
22. 1H MR spectra: a comparison of classification using whole spectra versus metabolite quantification. NMR Biomed 2007;20:763-770.
23. 1H magnetic resonance spectroscopy. Magn Reson Med 2003;49:223-232.
24. Shank RP, Aprison MH. Post mortem changes in the content and specific radioactivity of several amino acids in four areas of the rat brain. J Neurobiol 1971;2:145-151.
25. Benzi G, Pastoris O, Dossena M. Relationships between gamma-minobutyrate and succinate cycles during and after cerebral ischemia. J Neurosci Res 1982;7:193-201.
26. Perry TL, Hansen S, Gandham SS. Postmortem changes of amino compounds in human and rat brain. J Neurochem 1981;36: 406-410.
27. 1H NMR. NMR Biomed 2008:21:1138-1147.
28. Kugel H, Heindel W, Ernestus RI, Bunke J, du Mesnil R, Friedmann G. Human brain tumors: spectral patterns detected with localized H-1 MR spectroscopy. Radiology 1992;183: 701-709.
29. Michaelis T, Helms G, Frahm J. Metabolic alterations in brain autopsies: proton NMR identification of free glycerol. NMR Biomed 1996;9:121-124.
30. Petroff OA, Ogino T, Alger JR. High-resolution proton magnetic resonance spectroscopy of rabbit brain: regional metabolite levels and postmortem changes. J Neurochem 1988;51:163-171.
31. 1H proton spectroscopic imaging of the human brain. Magn Reson Imaging 2004;22:523-528.
32. Govindaraju V, Young K, Maudsley AA. Proton NMR chemical shifts and coupling constants for brain metabolites. NMR Biomed 2000;13:129-153.
33. 1H-MRS in vivo at 3.0T. Magn Reson Med 2008;59: 59-64.
34. 1H NMR spectroscopic investigation. NMR Biomed 2005;18:371-382.
35. Kinoshita Y, Yokota A. Absolute concentrations of metabolites in human brain tumors using in vitro proton magnetic resonance spectroscopy. NMR Biomed 1997;10:2-12.
36. 1H HR-MAS spectroscopy. Magn Reson Med 2006;55:1257-1264.
37. Gill SS, Thomas DG, Van Bruggen N, et al. Proton MR spectroscopy of intracranial tumours: in vivo and in vitro studies. J Comput Assist Tomogr 1990;14:497-504.
38. Ng WH, Lim T. Targeting regions with highest lipid content on MR spectroscopy may improve diagnostic yield in stereotactic biopsy. J Clin Neurosci 2008:15:502-506.
39. 1H MRS in vivo in brain tumors: experience of the Siemens cooperative clinical trial. Anticancer Res 1996;16:1533-1538.
40. Murphy PS, Rowland IJ, Viviers L, Brada M, Leach MO, Dzik-Jurasz AS. Could assessment of glioma methylene lipid resonance by in vivo (1)H-MRS be of clinical value? Br J Radiol 2003;76:459-463.
41. 1H nuclear magnetic resonance correspond to lipid droplets. Cancer Res 1997;57:407-414.
42. 1H-MRS lipid signal, necrosis and lipid droplets during C6 rat glioma development. NMR Biomed 2003;16:199-212.
43. Rutgers DR, van der Grond J. Relaxation times of choline, creatine and N-acetyl aspartate in human cerebral white matter at 1.5 T. NMR Biomed 2002;15:215-221.
44. 2 relaxation times of lipid and macromolecules: a study of high-grade tumor spectra. J Magn Reson Imaging 2008:27:178-184.