Apparent T2 relaxation times of lipid and macromolecules: A study of high-grade tumor spectra

Journal of Magnetic Resonance Imaging

Volumn 27, Issue 1, 2008, Pages 178-184

  Opstad, Kirstie S ^a   Griffiths, John R ^b   Bell, B Anthony ^a   Howe, Franklyn A ^a  

^a ST GEORGE'S UNIVERSITY OF LONDON   (United Kingdom)

^b IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

Author keywords

1H MRS; Glioblastoma; Metastases; Mobile lipid; T2; Tumor

Indexed keywords

LIPID; N ACETYLASPARTIC ACID;

ARTICLE; CANCER GRADING; CLINICAL ARTICLE; CONTROLLED STUDY; GLIOBLASTOMA; HUMAN; MACROMOLECULE; METABOLITE; METASTASIS; MUCOCELE; PHANTOM; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE;

BRAIN NEOPLASMS; FAT EMULSIONS, INTRAVENOUS; FEMALE; GLIOBLASTOMA; HUMANS; LIPID METABOLISM; MACROMOLECULAR SUBSTANCES; MAGNETIC RESONANCE SPECTROSCOPY; MALE; PHANTOMS, IMAGING; STATISTICS, NONPARAMETRIC;

EID: 37849021559     PISSN: 10531807     EISSN: 15222586     Source Type: Journal    
DOI: 10.1002/jmri.21223     Document Type: Article

References (36)

1. Bernstein M, Parrent AG. Complications of CT-guided stereotactic biopsy of intra-axial brain lesions. J Neurosurg 1994;81:165-168.
2. Lin A, Bluml S, Mamelak AN. Efficacy of proton magnetic resonance spectroscopy in clinical decision making for patients with suspected malignant brain tumors. J Neurooncol 1999;45:69-81.
3. Moller-Hartmann W, Herminghaus S, et al. Clinical application of proton magnetic resonance spectroscopy in the diagnosis of intracranial mass lesions. Neuroradiology 2002;44:371-381.
4. 1HMRS) to clinical brain tumour diagnosis. Br J Neurosurg 2002;16:329-334.
5. 1H brain tumor spectra: a multicenter study. Magn Reson Med 2003;49:29-36.
6. Herminghaus S, Dierks T, Pilatus U, et al. Determination of histopathological tumor grade in neuroepithelial brain tumors by using spectral pattern analysis of in vivo spectroscopic data. J Neurosurg 2003;98:74-81.
7. Majos C, Julia-Sape M, Alonso J, et al. Brain tumor classification by proton MR spectroscopy: comparison of diagnostic accuracy at short and long TE. AJNR Am J Neuroradiol 2004;25:1696-1704.
8. Devos A, Lukas L, Suykens JA, et al. Classification of brain tumors using short echo time 1H MR spectra. J Magn Reson 2004;170: 164-175.
9. 1H MR spectra: a comparison of classification using whole spectra versus metabolite quantification. NMR Biomed (in press).
10. Preul MC, Caramanos Z, Leblanc R, Villemure JG, Arnold DL. Using pattern analysis of in vivo proton MRSI data to improve the diagnosis and surgical management of patients with brain tumors. NMR Biomed 1998;11:192-200.
11. Burtscher IM, Skagerberg G, Geijer B, Englund E, Stahlberg F, Holtas S. Proton MR spectroscopy and preoperative diagnostic accuracy: an evaluation of intracranial mass lesions characterized by stereotactic biopsy findings. AJNR Am J Neuroradiol 2000;21:84-93.
12. 1H spectroscopy. J Magn Reson Imaging 2004;20: 187-192.
13. Behar KL, Ogino T. Characterization of macromolecule resonances in the 1H NMR spectrum of rat brain. Magn Reson Med 1993;30: 38-44.
14. Kleihues P, Burger PC, Scheithauer BW. Histological typing of tumours of the central nervous system, 2nd edition. Berlin: World Health Organization, Springer-Verlag; 1993. 112 p.
15. Webb PG, Sailasuta N, Kohler SJ, Raidy T, Moats RA, Hurd RE. Automated single-voxel proton MRS: technical development and multisite verification. Magn Reson Med 1994;31:365-373.
16. Vanhamme L, van den Boogaart A, Van Huffel S. Improved method for accurate and efficient quantification of MRS data with use of prior knowledge. J Magn Reson 1997;129:35-43.
17. 1H NMR spectra of human brain. Magn Reson Med 1994;32:294-302.
18. 1H MRS of high grade astrocytomas: mobile lipid accumulation in necrotic tissue. NMR Biomed 1994;7:149-155.
19. Mader I, Seeger U, Karitzky J, Erb M, Schick F, Klose U. Proton magnetic resonance spectroscopy with metabolite nulling reveals regional differences of macromolecules in normal human brain. J Magn Reson Imaging 2002;16:538-546.
20. Seeger U, Klose U, Mader I, Grodd W, Nagele T. Parameterized evaluation of macromolecules and lipids in proton MR spectroscopy of brain diseases. Magn Reson Med 2003;49:19-28.
21. Provencher SW. Estimation of metabolite concentrations from localized in vivo proton NMR spectra. Magn Reson Med 1993;30:672-679.
22. Greenberg HS, Chandler WF, Sandler HM. Brain tumours. New York: Oxford University Press; 1999. p 4.
23. 1H-NMR-detectable mobile lipid domains in NIH-3T3 fibroblasts. Biochim Biophys Acta 1999;1438:329-348.
24. Kreis R, Ernst T, Ross BD. Development of the human brain: in vivo quantification of metabolite and water content with proton magnetic resonance spectroscopy. Magn Reson Med 1993;30:424-437.
25. Usenius JP, Kauppinen RA, Vainio PA, et al. Quantitative metabolite patterns of human brain tumors: detection by 1H NMR spectroscopy in vivo and in vitro. J Comput Assist Tomogr 1994;18: 705-713.
26. Manton DJ, Lowry M, Blackband SJ, Horsman A. Determination of proton metabolite concentrations and relaxation parameters in normal human brain and intracranial tumours. NMR Biomed 1995;8:104-112.
27. Rutgers DR, van der Grond J. Relaxation times of choline, creatine and N-acetyl aspartate in human cerebral white matter at 1.5 T. NMR Biomed 2002;15:215-221.
28. Isobe T, Matsumura A, Anno I, et al. Quantification of cerebral metabolites in glioma patients with proton MR spectroscopy using T2 relaxation time correction. Magn Reson Imaging 2002;20:343-349.
29. 1H-MRS resonance at 2.05 ppm in mucin producing adenocarcinoma metastases in the brain. In: Proceedings of the 12th Annual Meeting of ISMRM, Kyoto, Japan, 2004 (Abstract 2080).
30. Brown EB, Brey Jr WS, Weltner Jr W. Cell-surface carbohydrates and their interactions. I: NMR of N-acetyl neuraminic acid. Biochim Biophys Acta 1975;399:124-130.
31. Andre E, Xu M, Yang D, et al. MR spectroscopy in sinus mucocele: N-acetyl mimics of brain N-acetylaspartate. AJNR Am J Neuroradiol 2006;27:2210-2213.
32. 1H MRS in vivo in brain tumors: experience of the Siemens cooperative clinical trial. Anticancer Res 1996;16:1533-1538.
33. 1H magnetic resonance spectroscopy. Magn Reson Med 2003;49:223-232.
34. Murphy PS, Rowland IJ, Viviers L, Brada M, Leach MO, Dzik-Jurasz AS. Could assessment of glioma methylene lipid resonance by in vivo (1)H-MRS be of clinical value? Br J Radiol 2003;76:459-463.
35. Kuesel AC, Briere KM, Halliday WC, Sutherland GR, Donnelly SM, Smith IC. Mobile lipid accumulation in necrotic tissue of high grade astrocytomas. Anticancer Res 1996;16:1485-1489.
36. 1H MRS of human brain tumour cystic fluid: contribution of macromolecules. MAGMA 2004;17:36-46.