The prairie vole: an emerging model organism for understanding the social brain

Trends in Neurosciences

Volumn 33, Issue 2, 2010, Pages 103-109

  McGraw, Lisa A ^a   Young, Larry J ^a,b  

^a EMORY UNIVERSITY   (United States)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL BEHAVIOR; AUTISM; BEHAVIOR GENETICS; BIOLOGICAL MODEL; BRAIN FUNCTION; COGNITIVE DEFECT; DEPRESSION; GENETIC ASSOCIATION; GENOME ANALYSIS; HEART DISEASE; HUMAN; HUMAN VERSUS ANIMAL COMPARISON; MOLECULAR DYNAMICS; MONOGAMY; NEUROBIOLOGY; NEUROMODULATION; NONHUMAN; NURTURING BEHAVIOR; PARENTAL BEHAVIOR; PRIORITY JOURNAL; REVIEW; SCHIZOPHRENIA; SOCIAL ADAPTATION; SOCIAL ASPECT; SOCIAL ATTITUDE; SOCIAL BEHAVIOR; SOCIAL INTERACTION; SOCIAL ISOLATION; VOLE;

ANIMALS; ARVICOLINAE; BEHAVIOR, ANIMAL; BRAIN; DEPRESSION; HEART DISEASES; METAGENOMICS; MODELS, ANIMAL; NEURAL PATHWAYS; NEUROGENESIS; SOCIAL BEHAVIOR;

EID: 75749121482     PISSN: 01662236     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tins.2009.11.006     Document Type: Review

References (66)

1. Carter C.S., et al. Physiological substrates of mammalian monogamy: the prairie vole model. Neurosci. Biobehav. Rev. 19 (1995) 303-314
2. Young L.J., and Wang Z. The neurobiology of pair bonding. Nat. Neurosci. 7 (2004) 1048-1054
3. Ophir A., et al. Field tests of cis-regulatory variation at the prairie vole avpr1a locus: association with V1aR abundance but not sexual or social fidelity. Horm. Behav. 54 (2008) 694-702
4. Solomon N., and Crist T. Estimates of reproductive success for group-living prairie voles, Microtus ochrogaster, in high-density populations. Anim. Behav. 76 (2008) 881-892
5. Williams J., et al. Development of partner preferences in female prairie voles (Microtus ochrogaster): the role of social and sexual experience. Horm. Behav. 26 (1992) 339-349
6. Ahern T., et al. Evaluation of two automated metrics for analyzing partner preference tests. J. Neurosci. Methods 182 (2009) 180-188
7. Insel T.R., and Shapiro L.E. Oxytocin receptor distribution reflects social organization in monogamous and polygamous voles. Proc. Natl. Acad. Sci. U. S. A. 89 (1992) 5981-5985
8. Insel T.R., et al. Patterns of vasopressin receptor distribution associated with social organization in microtine rodents. J. Neurosci. 14 (1994) 5381-5392
9. Insel T.R., and Hulihan T. A gender-specific mechanism for pair bonding: oxytocin and partner preference formation in monogamous voles. Behav. Neurosci. 109 (1995) 782-789
10. Ross H.E., and Young L.J. Oxytocin and the neural mechanisms regulating social cognition and affiliative behavior. Front. Neuroendocrinol. 30 (2009) 534-547
11. Wang Z., et al. Immunoreactivity of central vasopressin and oxytocin pathways in microtine rodents: a quantitative comparative study. J. Comp. Neurol. 366 (1996) 726-737
12. Carter C.S., et al. Oxytocin, vasopressin and sociality. Prog. Brain Res. 170 (2008) 331-336
13. Young K.A., et al. The neurobiology of social attachment: a comparative approach to behavioral, neuroanatomical, and neurochemical studies. Comp. Biochem. Physiol. C Toxicol. Pharmacol. 148 (2008) 401-410
14. Young L.J., et al. Cellular mechanisms of social attachment. Horm. Behav. 40 (2001) 133-138
15. Williams J.R., et al. Oxytocin administered centrally facilitates formation of a partner preference in prairie voles (Microtus ochrogaster). J. Neuroendocrinol. 6 (1994) 247-250
16. Ross H.E., et al. Variation in oxytocin receptor density in the nucleus accumbens has differential effects on affiliative behaviors in monogamous and polygamous voles. J. Neurosci. 29 (2009) 1312-1318
17. Schorscher-Petcu A., et al. Distribution of vasopressin and oxytocin binding sites in the brain and upper spinal cord of the common marmoset. Neurosci. Lett. 461 (2009) 217-222
18. Cho M.M., et al. The effects of oxytocin and vasopressin on partner preferences in male and female prairie voles (Microtus ochrogaster). Behav. Neurosci. 113 (1999) 1071-1079
19. Winslow J., et al. A role for central vasopressin in pair bonding in monogamous prairie voles. Nature 365 (1993) 545-548
20. Lim M.M., and Young L.J. Vasopressin-dependent neural circuits underlying pair bond formation in the monogamous prairie vole. Neuroscience 125 (2004) 35-45
21. Liu Y., et al. Vasopressin in the lateral septum regulates pair bond formation in male prairie voles (Microtus ochrogaster). Behav. Neurosci. 115 (2001) 910-919
22. Young L.J., and Frank A. Beach Award. Oxytocin and vasopressin receptors and species-typical social behaviors. Horm. Behav. 36 (1999) 212-221
23. Lim M.M., et al. Enhanced partner preference in a promiscuous species by manipulating the expression of a single gene. Nature 429 (2004) 754-757
24. Liu Y., and Wang Z.X. Nucleus accumbens dopamine and oxytocin interact to regulate pair bond formation in female prairie voles. Neuroscience 121 (2003) 537-544
25. Aragona B.J., et al. A critical role for nucleus accumbens dopamine in partner preference formation of male prairie voles. J. Neurosci. 23 (2003) 3483-3490
26. Aragona B.J., et al. Nucleus accumbens dopamine differentially mediates the formation and maintenance of monogamous pair bonds. Nat. Neurosci. 9 (2006) 133-139
27. Aragona B., et al. Amphetamine reward in the monogamous prairie vole. Neurosci. Lett. 418 (2007) 190-194
28. Donaldson Z., and Young L. Oxytocin, vasopressin, and the neurogenetics of sociality. Science 322 (2008) 900-904
29. Hammock E.A.D., and Young L.J. On switches and knobs, microsatellites and monogamy. Trends Genet. 23 (2007) 209-212
30. Young L.J., et al. Increased affiliative response to vasopressin in mice expressing the vasopressin receptor from a monogamous vole. Nature 400 (1999) 766-768
31. Hammock E.A.D., and Young L.J. Microsatellite instability generates diversity in brain and sociobehavioral traits. Science 308 (2005) 1630-1634
32. Fink S., et al. Mammalian monogamy is not controlled by a single gene. Proc. Natl. Acad. Sci. U. S. A. 103 (2006) 10956-10960
33. Olazábal D.E., and Young L.J. Oxytocin receptors in the nucleus accumbens facilitate "spontaneous" maternal behavior in adult female prairie voles. Neuroscience 141 (2006) 559-568
34. Olazábal D.E., and Young L.J. Species and individual differences in juvenile female alloparental care are associated with oxytocin receptor density in the striatum and the lateral septum. Horm. Behev. 49 (2006) 681-687
35. Ross H., et al. Variation in oxytocin receptor density in the nucleus accumbens has differential effects on affiliative behaviors in monogamous and polygamous voles. J. Neurosci. 29 (2009) 1312-1318
36. Bamshad M., et al. Cohabitation alters vasopressin innervation and paternal behavior in prairie voles (Microtus ochrogaster). Physiol. Behav. 56 (1994) 751-758
37. Bamshad M., et al. Sex and species differences in the vasopressin innervation of sexually naive and parental prairie voles, Microtus ochrogaster and meadow voles, M. pennsylvanicus. J. Neuroendocrinol. 5 (1993) 247-255
38. Wang Z., et al. Role of septal vasopressin innervation in paternal behavior in prairie voles (Microtus ochrogaster). Proc. Natl. Acad. Sci. U. S. A. 91 (1994) 400-404
39. Ahern T.H., and Young L.J. The impact of early life family structure on adult social attachment, alloparental behavior, and the neuropeptide systems regulating affiliative behaviors in the monogamous prairie vole (Microtus ochrogaster). Front. Behav. Neurosci. 3 (2009) 17
40. Heim C., et al. Lower CSF oxytocin concentrations in women with a history of childhood abuse. Mol. Psychiatry 10 (2009) 954-958
41. Grippo A., et al. Depression-like behavior and stressor-induced neuroendocrine activation in female prairie voles exposed to chronic social isolation. Psychosom. Med. 69 (2007) 149-157
42. Grippo A.J., et al. Social isolation disrupts autonomic regulation of the heart and influences negative affective behaviors. Biol. Psychiatry 62 (2007) 1162-1170
43. Grippo A., et al. Oxytocin protects against negative behavioral and autonomic consequences of long-term social isolation. Psychoneuroendocrinology 34 (2009) 1542-1553
44. Bosch O., et al. The CRF system mediates increased passive stress-coping behavior following the loss of a bonded partner in a monogamous rodent. Neuropsychopharmacology 34 (2009) 1406-1415
45. Heinrichs M., et al. Oxytocin, vasopressin, and human social behavior. Front. Neuroendocrinol. 30 (2009) 548-557
46. Hollander E., et al. Oxytocin increases retention of social cognition in autism. Biol. Psychiatry 61 (2006) 498-503
47. Kim S., et al. Transmission disequilibrium testing of arginine vasopressin receptor 1A (AVPR1A) polymorphisms in autism. Mol. Psychiatry 7 (2001) 503-507
48. Wassink T.H., et al. Examination of AVPR1a as an autism susceptibility gene. Mol. Psychiatry 9 (2004) 968-972
49. Yirmiya N., et al. Association between the arginine vasopressin 1a receptor (AVPR1a) gene and autism in a family-based study: mediation by socialization skills. Mol. Psychiatry 11 (2006) 488-494
50. Walum H., et al. Genetic variation in the vasopressin receptor 1a gene (AVPR1A) associates with pair-bonding behavior in humans. Proc. Natl. Acad. Sci. U. S. A. 105 (2008) 14153-14156
51. Donaldson Z.R., et al. Production of germline transgenic prairie voles (Microtus ochrogaster) using lentiviral vectors. Biol. Reprod. 81 (2009) 1189-1195
52. Getz L., et al. Social organization and mating system of the prairie vole, Microtus ochrogaster. In: Tamarin T., et al. (Ed). Social Systems and Population Cycles in Voles (1990), Birkhauser Verlag 69-80
53. Getz L.L., et al. The mating system of the prairie vole Microtus ochrogaster: field and laboratory evidence for pair bonding. Behav. Ecol. Sociobiol. 8 (1981) 189-194
54. Getz L., and Hoffman J. Social-organization in free-living prairie voles, Microtus ochrogaster. Behav. Ecol. Sociobiol. 18 (1986) 275-282
55. Hoffman J., et al. Home range overlap and nest cohabitation of male and female prairie voles. Am. Midl. Nat. 112 (1984) 314-319
56. Pizzuto T., and Getz L. Female prairie voles (Microtus ochrogaster) fail to form a new pair after loss of mate. Behav. Processes 43 (1998) 79-86
57. Getz L., et al. Social organization of the prairie vole (Microtus ochrogaster). J. Mammal. 74 (1993) 44-58
58. Thomas J., and Birney E. Parental care and mating system of the prairie vole, Microtus ochrogaster. Behav. Ecol. Sociobiol. 5 (1979) 171-186
59. Ophir A., et al. Social but not genetic monogamy is associated with greater breeding success in prairie voles. Anim. Behav. 75 (2008) 1143-1154
60. Solomon N., and Keane B. Reproductive strategies in female rodents. In: Sherman P., and Wolff J. (Eds). In Rodent Societies: An Ecological and Evolutionary Perspective (2007), The University of Chicago Press 42-56
61. Roberts R.L., et al. Role of social and endocrine factors in alloparental behavior of prairie voles (Microtus ochrogaster). Can. J. Zool. 76 (1998) 1862-1868
62. Cushing B., et al. The effects of peptides on partner preference formation are predicted by habitat in prairie voles. Horm. Behav. 39 (2001) 48-58
63. Cushing B.S., and Kramer K.M. Microtines: a model system for studying the evolution and regulation of social monogamy. Acta Theriol Sinica 25 (2005) 182-199
64. Cushing B., et al. Intraspecific variation in estrogen receptor alpha and the expression of male sociosexual behavior in two populations of prairie voles. Brain Res. 1016 (2004) 247-254
65. Ahern T.H., et al. Evaluation of two automated metrics for analyzing partner preference tests. J. Neurosci. Methods 182 (2009) 180-188
66. Young L.J., et al. Anatomy and neurochemistry of the pair bond. J. Comp. Neurol. 493 (2005) 51-57