메뉴 건너뛰기




Volumn 9, Issue 4, 2009, Pages 344-352

MHC class I TCR engineered anti-tumor CD4 T cells: Implications for cancer immunotherapy

Author keywords

Cancer; Immunotherapy; MHC class I TCR engineered CD4 T cells

Indexed keywords

CANCER VACCINE; COMPLEMENTARY DNA; DENDRITIC CELL VACCINE; LENTIVIRUS VECTOR; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; RETROVIRUS VECTOR; SYNTHETIC PEPTIDE; T LYMPHOCYTE RECEPTOR;

EID: 75749110973     PISSN: 18715303     EISSN: None     Source Type: Journal    
DOI: 10.2174/187153009789839183     Document Type: Review
Times cited : (10)

References (77)
  • 1
    • 84965092294 scopus 로고
    • Cancer; a biological approach. I: The processes of control
    • Burnet, M. (1957) Cancer; a biological approach. I: the processes of control. Br. Med. J., 1, 779-786.
    • (1957) Br. Med. J , vol.1 , pp. 779-786
    • Burnet, M.1
  • 2
    • 0036852241 scopus 로고    scopus 로고
    • Cancer immunoediting: From immunosurveillance to tumor escape
    • Dunn, G.P.; Bruce, A.T.; Ikeda, H.; Old, L.J. and Schreiber, R.D. (2002) Cancer immunoediting: from immunosurveillance to tumor escape. Nat. Immunol., 3, 991-998.
    • (2002) Nat. Immunol , vol.3 , pp. 991-998
    • Dunn, G.P.1    Bruce, A.T.2    Ikeda, H.3    Old, L.J.4    Schreiber, R.D.5
  • 3
    • 0020640641 scopus 로고
    • Clonal analysis of cytotoxic T cell response against human melanoma
    • Mukherji, B. and MacAlister, T.J. (1983) Clonal analysis of cytotoxic T cell response against human melanoma. J. Exp. Med., 158, 240-245.
    • (1983) J. Exp. Med , vol.158 , pp. 240-245
    • Mukherji, B.1    MacAlister, T.J.2
  • 4
    • 0021344880 scopus 로고
    • Cloned human cytotoxic T lymphocyte (CTL) lines reactive with autologous melanoma cells. I. In vitro generation, isolation, and analysis to phenotype and specificity
    • de Vries, J.E. and Spits, H. (1984) Cloned human cytotoxic T lymphocyte (CTL) lines reactive with autologous melanoma cells. I. In vitro generation, isolation, and analysis to phenotype and specificity. J. Immunol., 132, 510-519.
    • (1984) J. Immunol , vol.132 , pp. 510-519
    • de Vries, J.E.1    Spits, H.2
  • 5
    • 3142541510 scopus 로고
    • Tcell-mediated cytotoxicity against autologous malignant melanoma: Analysis with interleukin 2-dependent T-cell cultures
    • Knuth, A.; Danowski, B.; Oettgen, H.F. and Old, L.J. (1984) Tcell-mediated cytotoxicity against autologous malignant melanoma: analysis with interleukin 2-dependent T-cell cultures. Proc. Natl. Acad. Sci. USA, 81, 3511-3515.
    • (1984) Proc. Natl. Acad. Sci. USA , vol.81 , pp. 3511-3515
    • Knuth, A.1    Danowski, B.2    Oettgen, H.F.3    Old, L.J.4
  • 7
    • 12944325331 scopus 로고    scopus 로고
    • A listing of human tumor antigens recognized by T cells: March 2004 update
    • Novellino, L.; Castelli, C. and Parmiani, G. (2005) A listing of human tumor antigens recognized by T cells: March 2004 update. Cancer Immunol. Immunother., 54, 187-207.
    • (2005) Cancer Immunol. Immunother , vol.54 , pp. 187-207
    • Novellino, L.1    Castelli, C.2    Parmiani, G.3
  • 8
    • 0025735629 scopus 로고
    • The dendritic cell system and its role in immunogenicity
    • Steinman, R.M. (1991) The dendritic cell system and its role in immunogenicity. Annu. Rev. Immunol., 9, 271-296.
    • (1991) Annu. Rev. Immunol , vol.9 , pp. 271-296
    • Steinman, R.M.1
  • 9
    • 0026481133 scopus 로고
    • Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor
    • Inaba, K.; Inaba, M.; Romani, N.; Aya, H.; Deguchi, M.; Ikehara, S.; Muramatsu, S. and Steinman, R.M. (1992) Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor. J. Exp. Med., 176, 1693-1702.
    • (1992) J. Exp. Med , vol.176 , pp. 1693-1702
    • Inaba, K.1    Inaba, M.2    Romani, N.3    Aya, H.4    Deguchi, M.5    Ikehara, S.6    Muramatsu, S.7    Steinman, R.M.8
  • 10
    • 0028289244 scopus 로고
    • Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha
    • Sallusto, F. and Lanzavecchia, A. (1994) Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha. J. Exp. Med., 179, 1109-1118.
    • (1994) J. Exp. Med , vol.179 , pp. 1109-1118
    • Sallusto, F.1    Lanzavecchia, A.2
  • 11
    • 0033051081 scopus 로고    scopus 로고
    • Dendritic cell vaccines for cancer immunotherapy
    • Timmerman, J.M. and Levy, R. (1999) Dendritic cell vaccines for cancer immunotherapy. Annu. Rev. Med., 50, 507-529.
    • (1999) Annu. Rev. Med , vol.50 , pp. 507-529
    • Timmerman, J.M.1    Levy, R.2
  • 12
    • 0035902080 scopus 로고    scopus 로고
    • Progress in human tumour immunology and immunotherapy
    • Rosenberg, S.A. (2001) Progress in human tumour immunology and immunotherapy. Nature, 411, 380-384.
    • (2001) Nature , vol.411 , pp. 380-384
    • Rosenberg, S.A.1
  • 13
    • 4644324025 scopus 로고    scopus 로고
    • Cancer immunotherapy: Moving beyond current vaccines
    • Rosenberg, S.A.; Yang, J.C. and Restifo, N.P. (2004) Cancer immunotherapy: moving beyond current vaccines. Nat. Med., 10, 909-915.
    • (2004) Nat. Med , vol.10 , pp. 909-915
    • Rosenberg, S.A.1    Yang, J.C.2    Restifo, N.P.3
  • 14
    • 34248204110 scopus 로고    scopus 로고
    • DC-based cancer vaccines
    • Gilboa, E. (2007) DC-based cancer vaccines. J. Clin. Invest., 117, 1195-1203.
    • (2007) J. Clin. Invest , vol.117 , pp. 1195-1203
    • Gilboa, E.1
  • 16
    • 0013974537 scopus 로고
    • Effect of leukocytes on transplantability of human cancer
    • Southam, C.M.; Brunschwig, A; Levin, A.G. and Dizon, Q.S. (1966) Effect of leukocytes on transplantability of human cancer. Cancer, 19, 1743-1753.
    • (1966) Cancer , vol.19 , pp. 1743-1753
    • Southam, C.M.1    Brunschwig, A.2    Levin, A.G.3    Dizon, Q.S.4
  • 19
    • 0033579934 scopus 로고    scopus 로고
    • Marchand, M.; van Baren, N.; Weynants, P.; Brichard, V.; Dreno, B.; Tessier, M.H.; Rankin, E.; Parmiani, G.; Arienti, Y.; Humblet, A.; Bourlond, R.; Vanwijck, D.; Lienard, M.; Beauduin, P.; Dietrich, Y.; Russo, V.; Kerger, J.; Masucci, G.; Jager, E.; De Greve, J.; Atzpodien, J.; Brasseur, F.; Coulie, P.G.; van der Bruggen, P. and Boon, T. (1999) Tumor regressions observed in patients with metastatic melanoma treated with an antigenic peptide encoded by gene MAGE-3 and presented by HLA-A1. Int. J. Cancer, 80, 219-230.
    • Marchand, M.; van Baren, N.; Weynants, P.; Brichard, V.; Dreno, B.; Tessier, M.H.; Rankin, E.; Parmiani, G.; Arienti, Y.; Humblet, A.; Bourlond, R.; Vanwijck, D.; Lienard, M.; Beauduin, P.; Dietrich, Y.; Russo, V.; Kerger, J.; Masucci, G.; Jager, E.; De Greve, J.; Atzpodien, J.; Brasseur, F.; Coulie, P.G.; van der Bruggen, P. and Boon, T. (1999) Tumor regressions observed in patients with metastatic melanoma treated with an antigenic peptide encoded by gene MAGE-3 and presented by HLA-A1. Int. J. Cancer, 80, 219-230.
  • 20
    • 0032724112 scopus 로고    scopus 로고
    • Phase I trial of a MART-1 peptide vaccine with incomplete Freund's adjuvant for resected high-risk melanoma
    • Wang, F.; Bade, E.; Kuniyoshi, C.; Spears, L.; Jeffery, G.; Marty, V.; Groshen, S. and Weber, J. (1999) Phase I trial of a MART-1 peptide vaccine with incomplete Freund's adjuvant for resected high-risk melanoma. Clin. Cancer Res., 5, 2756-2765.
    • (1999) Clin. Cancer Res , vol.5 , pp. 2756-2765
    • Wang, F.1    Bade, E.2    Kuniyoshi, C.3    Spears, L.4    Jeffery, G.5    Marty, V.6    Groshen, S.7    Weber, J.8
  • 24
    • 0036813199 scopus 로고    scopus 로고
    • GM-CSF-based cancer vaccines
    • Dranoff, G. (2002) GM-CSF-based cancer vaccines. Immunol. Rev., 188, 147-154.
    • (2002) Immunol. Rev , vol.188 , pp. 147-154
    • Dranoff, G.1
  • 26
    • 7244248658 scopus 로고    scopus 로고
    • Cross-presentation of a human tumor antigen delivered to dendritic cells by HSV VP22-mediated protein translocation
    • Chhabra, A.; Mehrotra, S.; Chakraborty, N.G.; Mukherji, B. and Dorsky, D.I. (2004) Cross-presentation of a human tumor antigen delivered to dendritic cells by HSV VP22-mediated protein translocation. Eur. J. Immunol., 34, 2824-2833.
    • (2004) Eur. J. Immunol , vol.34 , pp. 2824-2833
    • Chhabra, A.1    Mehrotra, S.2    Chakraborty, N.G.3    Mukherji, B.4    Dorsky, D.I.5
  • 27
    • 60649096118 scopus 로고    scopus 로고
    • Lentiviral vectors for anti-tumor immunotherapy
    • Breckpot, K.; Emeagi, P.U. and Thielemans, K. (2008) Lentiviral vectors for anti-tumor immunotherapy. Curr. Gene Ther., 8, 438-448.
    • (2008) Curr. Gene Ther , vol.8 , pp. 438-448
    • Breckpot, K.1    Emeagi, P.U.2    Thielemans, K.3
  • 28
    • 0031960397 scopus 로고    scopus 로고
    • Induction of primary carcinoembryonic antigen (CEA)-specific cytotoxic T lymphocytes in vitro using human dendritic cells transfected with RNA
    • Nair, S.K.; Boczkowski, D.; Morse, M.; Cumming, R.I.; Lyerly, H.K. and Gilboa, E. (1998) Induction of primary carcinoembryonic antigen (CEA)-specific cytotoxic T lymphocytes in vitro using human dendritic cells transfected with RNA. Nat. Biotechnol., 16, 364-369.
    • (1998) Nat. Biotechnol , vol.16 , pp. 364-369
    • Nair, S.K.1    Boczkowski, D.2    Morse, M.3    Cumming, R.I.4    Lyerly, H.K.5    Gilboa, E.6
  • 29
    • 0035412401 scopus 로고    scopus 로고
    • Highly efficient gene delivery by mRNA electroporation in human hematopoietic cells: Superiority to lipofection and passive pulsing of mRNA and to electroporation of plasmid cDNA for tumor antigen loading of dendritic cells
    • Van Tendeloo, V.F.; Ponsaerts, P.; Lardon, F.; Nijs, G.; Lenjou, M.; Van Broeckhoven, C.; Van Bockstaele, D.R. and Berneman, Z.N. (2001) Highly efficient gene delivery by mRNA electroporation in human hematopoietic cells: superiority to lipofection and passive pulsing of mRNA and to electroporation of plasmid cDNA for tumor antigen loading of dendritic cells. Blood, 98, 49-56.
    • (2001) Blood , vol.98 , pp. 49-56
    • Van Tendeloo, V.F.1    Ponsaerts, P.2    Lardon, F.3    Nijs, G.4    Lenjou, M.5    Van Broeckhoven, C.6    Van Bockstaele, D.R.7    Berneman, Z.N.8
  • 30
    • 0001751833 scopus 로고
    • Studies on the immunological response to foreign tumor transplants in the mouse. I: The role of lymph node cells in conferring immunity by adoptive transfer
    • Mitchison, N.A. (1955) Studies on the immunological response to foreign tumor transplants in the mouse. I: the role of lymph node cells in conferring immunity by adoptive transfer. J. Exp. Med., 102, 157-177.
    • (1955) J. Exp. Med , vol.102 , pp. 157-177
    • Mitchison, N.A.1
  • 31
    • 0019951384 scopus 로고
    • Lymphokine-activated killer cell phenomenon. Lysis of natural killer-resistant fresh solid tumor cells by interleukin 2-activated autologous human peripheral blood lymphocytes
    • Grimm, E.A.; Mazumder, A.; Zhang, H.Z. and Rosenberg, S.A. (1982) Lymphokine-activated killer cell phenomenon. Lysis of natural killer-resistant fresh solid tumor cells by interleukin 2-activated autologous human peripheral blood lymphocytes. J. Exp. Med., 155, 1823-1841.
    • (1982) J. Exp. Med , vol.155 , pp. 1823-1841
    • Grimm, E.A.1    Mazumder, A.2    Zhang, H.Z.3    Rosenberg, S.A.4
  • 33
    • 0022473607 scopus 로고
    • A new approach to the adoptive immunotherapy of cancer with tumorinfiltrating lymphocytes
    • Rosenberg, S.A.; Spiess, P. and Lafreniere, R. (1986) A new approach to the adoptive immunotherapy of cancer with tumorinfiltrating lymphocytes. Science, 233, 1318-1321.
    • (1986) Science , vol.233 , pp. 1318-1321
    • Rosenberg, S.A.1    Spiess, P.2    Lafreniere, R.3
  • 34
    • 0037058993 scopus 로고    scopus 로고
    • Adoptive T cell therapy using antigen-specific CD8+ T cell clones for the treatment of patients with metastatic melanoma: In vivo persistence, migration, and antitumor effect of transferred T cells
    • Yee, C.; Thompson, J.A.; Byrd, D.; Riddell, S.R.; Roche, P.; Celis, E. and Greenberg, P.D. (2002) Adoptive T cell therapy using antigen-specific CD8+ T cell clones for the treatment of patients with metastatic melanoma: in vivo persistence, migration, and antitumor effect of transferred T cells. Proc. Natl. Acad. Sci. USA, 99, 16168-16173.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 16168-16173
    • Yee, C.1    Thompson, J.A.2    Byrd, D.3    Riddell, S.R.4    Roche, P.5    Celis, E.6    Greenberg, P.D.7
  • 35
    • 20244366111 scopus 로고    scopus 로고
    • Dudley, M.E.; Wunderlich, J.R.; Yang, J.C.; Sherry, R.M.; Topalian, S.L.; Restifo, N.P.; Royal, R.E.; Kammula, U.; White, D.E.; Mavroukakis, S.A.; Rogers, L.J.; Gracia, G.J.; Jones, S.A.; Mangiameli, D.P.; Pelletier, M.M.; Gea-Banacloche, J.; Robinson, M.R.; Berman, D.M.; Filie, A.C.; Abati, A. and Rosenberg, S.A. (2005) Adoptive cell transfer therapy following non-myeloablative but lymphodepleting chemotherapy for the treatment of patients with refractory metastatic melanoma. J. Clin. Oncol., 23, 2346-2357.
    • Dudley, M.E.; Wunderlich, J.R.; Yang, J.C.; Sherry, R.M.; Topalian, S.L.; Restifo, N.P.; Royal, R.E.; Kammula, U.; White, D.E.; Mavroukakis, S.A.; Rogers, L.J.; Gracia, G.J.; Jones, S.A.; Mangiameli, D.P.; Pelletier, M.M.; Gea-Banacloche, J.; Robinson, M.R.; Berman, D.M.; Filie, A.C.; Abati, A. and Rosenberg, S.A. (2005) Adoptive cell transfer therapy following non-myeloablative but lymphodepleting chemotherapy for the treatment of patients with refractory metastatic melanoma. J. Clin. Oncol., 23, 2346-2357.
  • 37
    • 0037829421 scopus 로고    scopus 로고
    • Generation of tumor-infiltrating lymphocyte cultures for use in adoptive transfer therapy for melanoma patients
    • Dudley, M.E.; Wunderlich, J.R.; Shelton, T.E.; Even, J. and Rosenberg, S.A. (2003) Generation of tumor-infiltrating lymphocyte cultures for use in adoptive transfer therapy for melanoma patients. J. Immunother., 26, 332-342.
    • (2003) J. Immunother , vol.26 , pp. 332-342
    • Dudley, M.E.1    Wunderlich, J.R.2    Shelton, T.E.3    Even, J.4    Rosenberg, S.A.5
  • 39
    • 0033887418 scopus 로고    scopus 로고
    • Transfer of specificity for human immunodeficiency virus type 1 into primary human T lymphocytes by introduction of T-cell receptor genes
    • Cooper, L.J.; Kalos, M.; Lewinsohn, D.A.; Riddell, S.R. and Greenberg, P.D. (2000) Transfer of specificity for human immunodeficiency virus type 1 into primary human T lymphocytes by introduction of T-cell receptor genes. J. Virol., 74, 8207-8212.
    • (2000) J. Virol , vol.74 , pp. 8207-8212
    • Cooper, L.J.1    Kalos, M.2    Lewinsohn, D.A.3    Riddell, S.R.4    Greenberg, P.D.5
  • 40
    • 0035128975 scopus 로고    scopus 로고
    • Retroviral transduction of a T cell receptor specific for an Epstein-Barr virus-encoded peptide
    • Orentas, R.J.; Roskopf, S.J.; Nolan, G.P. and Nishimura, M.I. (2001) Retroviral transduction of a T cell receptor specific for an Epstein-Barr virus-encoded peptide. Clin. Immunol., 98, 220-228.
    • (2001) Clin. Immunol , vol.98 , pp. 220-228
    • Orentas, R.J.1    Roskopf, S.J.2    Nolan, G.P.3    Nishimura, M.I.4
  • 41
    • 0033168142 scopus 로고    scopus 로고
    • Efficient transfer of a tumor antigenreactive TCR to human peripheral blood lymphocytes confers antitumor reactivity
    • Clay, T.M.; Custer, M.C.; Sachs, J.; Hwu, P.; Rosenberg, S.A. and Nishimura, M.I. (1999) Efficient transfer of a tumor antigenreactive TCR to human peripheral blood lymphocytes confers antitumor reactivity. J. Immunol., 163, 507-513.
    • (1999) J. Immunol , vol.163 , pp. 507-513
    • Clay, T.M.1    Custer, M.C.2    Sachs, J.3    Hwu, P.4    Rosenberg, S.A.5    Nishimura, M.I.6
  • 43
    • 0036635506 scopus 로고    scopus 로고
    • T-cell-receptor gene therapy
    • Schumacher, T.N. (2002) T-cell-receptor gene therapy. Nat. Rev. Immunol., 2, 512-519.
    • (2002) Nat. Rev. Immunol , vol.2 , pp. 512-519
    • Schumacher, T.N.1
  • 44
    • 0028815876 scopus 로고
    • Characterization of the functional specificity of a cloned T-cell receptor heterodimer recognizing the MART-1 melanoma antigen
    • Cole, D.J.; Weil, D.P.; Shilyansky, J.; Custer, M.; Kawakami, Y.; Rosenberg, S.A. and Nishimura, M.I. (1995) Characterization of the functional specificity of a cloned T-cell receptor heterodimer recognizing the MART-1 melanoma antigen. Cancer Res., 55, 748-752.
    • (1995) Cancer Res , vol.55 , pp. 748-752
    • Cole, D.J.1    Weil, D.P.2    Shilyansky, J.3    Custer, M.4    Kawakami, Y.5    Rosenberg, S.A.6    Nishimura, M.I.7
  • 45
    • 1842631467 scopus 로고    scopus 로고
    • Reprogramming of virus-specific T cells into leukemia-reactive T cells using T cell receptor gene transfer
    • Heemskerk, M.H.; Hoogeboom, M.; Hagedoorn, R.; Kester, M.G.; Willemze, R. and Falkenburg, J.H. (2004) Reprogramming of virus-specific T cells into leukemia-reactive T cells using T cell receptor gene transfer. J. Exp Med., 199, 885-894.
    • (2004) J. Exp Med , vol.199 , pp. 885-894
    • Heemskerk, M.H.1    Hoogeboom, M.2    Hagedoorn, R.3    Kester, M.G.4    Willemze, R.5    Falkenburg, J.H.6
  • 47
    • 33749005425 scopus 로고    scopus 로고
    • Enhanced antitumor activity of murine-human hybrid T-cell receptor (TCR) in human lymphocytes is associated with improved pairing and TCR/CD3 stability
    • Cohen, C.J.; Zhao, Y.; Zheng, Z.; Rosenberg, S.A. and Morgan, R.A. (2006) Enhanced antitumor activity of murine-human hybrid T-cell receptor (TCR) in human lymphocytes is associated with improved pairing and TCR/CD3 stability. Cancer Res., 66, 8878-8886.
    • (2006) Cancer Res , vol.66 , pp. 8878-8886
    • Cohen, C.J.1    Zhao, Y.2    Zheng, Z.3    Rosenberg, S.A.4    Morgan, R.A.5
  • 48
    • 34248595961 scopus 로고    scopus 로고
    • Enhanced antitumor activity of T cells engineered to express T-cell receptors with a second disulfide bond
    • Cohen, C.J.; Li, Y.F.; El-Gamil, M.; Robbins, P.F.; Rosenberg, S.A. and Morgan, R.A. (2007) Enhanced antitumor activity of T cells engineered to express T-cell receptors with a second disulfide bond. Cancer Res., 67, 3898-3903.
    • (2007) Cancer Res , vol.67 , pp. 3898-3903
    • Cohen, C.J.1    Li, Y.F.2    El-Gamil, M.3    Robbins, P.F.4    Rosenberg, S.A.5    Morgan, R.A.6
  • 49
    • 4444370799 scopus 로고    scopus 로고
    • Gene therapy clinical trials worldwide 1989-2004-an overview
    • Edelstein, M.L.; Abedi, M.R.; Wixon, J. and Edelstein, R.M. (2004) Gene therapy clinical trials worldwide 1989-2004-an overview. J. Gene Med., 6, 597-602.
    • (2004) J. Gene Med , vol.6 , pp. 597-602
    • Edelstein, M.L.1    Abedi, M.R.2    Wixon, J.3    Edelstein, R.M.4
  • 51
    • 0020077493 scopus 로고
    • Helper activity is required for the in vivo generation of cytotoxic T lymphocytes
    • Keene, J.A. and Forman, J. (1982) Helper activity is required for the in vivo generation of cytotoxic T lymphocytes. J. Exp Med., 155, 768-782.
    • (1982) J. Exp Med , vol.155 , pp. 768-782
    • Keene, J.A.1    Forman, J.2
  • 52
    • 3543099130 scopus 로고    scopus 로고
    • Helping the CD8(+) T-cell response
    • Bevan, M.J. (2004) Helping the CD8(+) T-cell response. Nat. Rev. Immunol., 4, 595-602.
    • (2004) Nat. Rev. Immunol , vol.4 , pp. 595-602
    • Bevan, M.J.1
  • 53
    • 33746215291 scopus 로고    scopus 로고
    • Cutting edge: Cognate CD4 help promotes recruitment of antigen-specific CD8 T cells around dendritic cells
    • Beuneu, H.; Garcia, Z. and Bousso, P. (2006) Cutting edge: cognate CD4 help promotes recruitment of antigen-specific CD8 T cells around dendritic cells. J. Immunol., 177, 1406-1410.
    • (2006) J. Immunol , vol.177 , pp. 1406-1410
    • Beuneu, H.1    Garcia, Z.2    Bousso, P.3
  • 54
    • 0034027829 scopus 로고    scopus 로고
    • CD4+ T cells in adoptive immunotherapy and the indirect mechanism of tumor rejection
    • Cohen, P.A.; Peng, L.; Plautz, G.E.; Kim, J.A.; Weng, D.E. and Shu, S. (2000) CD4+ T cells in adoptive immunotherapy and the indirect mechanism of tumor rejection. Crit. Rev. Immunol., 20, 17-56.
    • (2000) Crit. Rev. Immunol , vol.20 , pp. 17-56
    • Cohen, P.A.1    Peng, L.2    Plautz, G.E.3    Kim, J.A.4    Weng, D.E.5    Shu, S.6
  • 56
    • 0032482274 scopus 로고    scopus 로고
    • Immunology. Licence to kill
    • Lanzavecchia, A. (1998) Immunology. Licence to kill. Nature, 393, 413-414.
    • (1998) Nature , vol.393 , pp. 413-414
    • Lanzavecchia, A.1
  • 57
    • 33747772051 scopus 로고    scopus 로고
    • T helper lymphocytes rescue CTL from activation-induced cell death
    • Kennedy, R. and Celis, E. (2006) T helper lymphocytes rescue CTL from activation-induced cell death. J. Immunol., 177, 2862-2872.
    • (2006) J. Immunol , vol.177 , pp. 2862-2872
    • Kennedy, R.1    Celis, E.2
  • 58
    • 0034541167 scopus 로고    scopus 로고
    • Tumor-specific CD4+ T cells have a major "post-licensing" role in CTL mediated antitumor immunity
    • Marzo, A.L.; Kinnear, B.F.; Lake, R.A.; Frelinger, J.J.; Collins, E.J.; Robinson, B.W. and Scott, B. (2000) Tumor-specific CD4+ T cells have a major "post-licensing" role in CTL mediated antitumor immunity. J. Immunol., 165, 6047-6055.
    • (2000) J. Immunol , vol.165 , pp. 6047-6055
    • Marzo, A.L.1    Kinnear, B.F.2    Lake, R.A.3    Frelinger, J.J.4    Collins, E.J.5    Robinson, B.W.6    Scott, B.7
  • 62
    • 0032404110 scopus 로고    scopus 로고
    • Generation of CD8+ and CD4+ T-cell response to dendritic cells genetically engineered to express the MART-1/Melan-A gene
    • Perez-Diez, A.; Butterfield, L.H.; Li, L.; Chakraborty, N.G.; Economou, J.S. and Mukherji, B. (1998) Generation of CD8+ and CD4+ T-cell response to dendritic cells genetically engineered to express the MART-1/Melan-A gene. Cancer Res., 58, 5305-5309.
    • (1998) Cancer Res , vol.58 , pp. 5305-5309
    • Perez-Diez, A.1    Butterfield, L.H.2    Li, L.3    Chakraborty, N.G.4    Economou, J.S.5    Mukherji, B.6
  • 65
    • 15444371764 scopus 로고    scopus 로고
    • Primary human lymphocytes transduced with NY-ESO-1 antigen-specific TCR genes recognize and kill diverse human tumor cell lines
    • Zhao, Y.; Zheng, Z.; Robbins, P.F.; Khong, H.T.; Rosenberg, S.A. and Morgan, R.A. (2005) Primary human lymphocytes transduced with NY-ESO-1 antigen-specific TCR genes recognize and kill diverse human tumor cell lines. J. Immunol., 174, 4415-4423.
    • (2005) J. Immunol , vol.174 , pp. 4415-4423
    • Zhao, Y.1    Zheng, Z.2    Robbins, P.F.3    Khong, H.T.4    Rosenberg, S.A.5    Morgan, R.A.6
  • 66
    • 33750324618 scopus 로고    scopus 로고
    • Gene transfer of tumor-reactive TCR confers both high avidity and tumor reactivity to nonreactive peripheral blood mononuclear cells and tumor-infiltrating lymphocytes
    • Johnson, L.A.; Heemskerk, B.; Powell, D.J.; Cohen, C.J.; Jr.; Morgan, R.A.; Dudley, M.E.; Robbins, P.F. and Rosenberg, S.A. (2006) Gene transfer of tumor-reactive TCR confers both high avidity and tumor reactivity to nonreactive peripheral blood mononuclear cells and tumor-infiltrating lymphocytes. J. Immunol., 177, 6548-6559.
    • (2006) J. Immunol , vol.177 , pp. 6548-6559
    • Johnson, L.A.1    Heemskerk, B.2    Powell, D.J.3    Cohen Jr., C.J.4    Morgan, R.A.5    Dudley, M.E.6    Robbins, P.F.7    Rosenberg, S.A.8
  • 67
    • 13944278036 scopus 로고    scopus 로고
    • Simultaneous generation of CD8+ and CD4+ melanoma-reactive T cells by retroviral-mediated transfer of a single T-cell receptor
    • Roszkowski, J.J.; Lyons, G.E.; Kast, W.M.; Yee, C.; Van Besien, K. and Nishimura, M.I. (2005) Simultaneous generation of CD8+ and CD4+ melanoma-reactive T cells by retroviral-mediated transfer of a single T-cell receptor. Cancer Res., 65, 1570-1576.
    • (2005) Cancer Res , vol.65 , pp. 1570-1576
    • Roszkowski, J.J.1    Lyons, G.E.2    Kast, W.M.3    Yee, C.4    Van Besien, K.5    Nishimura, M.I.6
  • 68
    • 13244265603 scopus 로고    scopus 로고
    • Redirecting human CD4+ T lymphocytes to the MHC class I-restricted melanoma antigen MAGE-A1 by TCR alphabeta gene transfer requires CD8alpha
    • Willemsen, R.; Ronteltap, C.; Heuveling, M.; Debets, R. and Bolhuis, R. (2005) Redirecting human CD4+ T lymphocytes to the MHC class I-restricted melanoma antigen MAGE-A1 by TCR alphabeta gene transfer requires CD8alpha. Gene Ther., 12, 140-146.
    • (2005) Gene Ther , vol.12 , pp. 140-146
    • Willemsen, R.1    Ronteltap, C.2    Heuveling, M.3    Debets, R.4    Bolhuis, R.5
  • 71
    • 33847647528 scopus 로고    scopus 로고
    • Regulatory T cells and cancer
    • Wang, H.Y. and Wang, R.F. (2007) Regulatory T cells and cancer. Curr. Opin. Immunol., 19, 217-223.
    • (2007) Curr. Opin. Immunol , vol.19 , pp. 217-223
    • Wang, H.Y.1    Wang, R.F.2
  • 72
    • 53549102755 scopus 로고    scopus 로고
    • The tumor microenvironment and its role in promoting tumor growth
    • Whiteside, T.L. (2008) The tumor microenvironment and its role in promoting tumor growth. Oncogene, 27, 5904-5912.
    • (2008) Oncogene , vol.27 , pp. 5904-5912
    • Whiteside, T.L.1
  • 73
    • 37349058220 scopus 로고    scopus 로고
    • Interactions of tumor cells with dendritic cells: Balancing immunity and tolerance
    • Dhodapkar, M.V.; Dhodapkar, K.M. and Palucka, A.K. (2008) Interactions of tumor cells with dendritic cells: balancing immunity and tolerance. Cell Death Differ., 15, 39-50.
    • (2008) Cell Death Differ , vol.15 , pp. 39-50
    • Dhodapkar, M.V.1    Dhodapkar, K.M.2    Palucka, A.K.3
  • 74
    • 53549087527 scopus 로고    scopus 로고
    • How tumours escape mass destruction
    • Stewart, T.J. and Abrams, S.I. (2008) How tumours escape mass destruction. Oncogene, 27, 5894-5903.
    • (2008) Oncogene , vol.27 , pp. 5894-5903
    • Stewart, T.J.1    Abrams, S.I.2
  • 75
    • 47249089536 scopus 로고    scopus 로고
    • PD-L1: PD-1 interaction contributes to the functional suppression of T-cell responses to human uveal melanoma cells in vitro
    • Yang, W.; Chen, P.W.; Li, H.; Alizadeh, H. and Niederkorn, J.Y. (2008) PD-L1: PD-1 interaction contributes to the functional suppression of T-cell responses to human uveal melanoma cells in vitro. Invest. Ophthalmol. Vis. Sci., 49, 2518-2525.
    • (2008) Invest. Ophthalmol. Vis. Sci , vol.49 , pp. 2518-2525
    • Yang, W.1    Chen, P.W.2    Li, H.3    Alizadeh, H.4    Niederkorn, J.Y.5
  • 77
    • 49149130306 scopus 로고    scopus 로고
    • Tumor-specific CD4+ T cells render the tumor environment permissive for infiltration by low-avidity CD8+ T cells
    • Wong, S.B.; Bos, R. and Sherman, L.A. (2008) Tumor-specific CD4+ T cells render the tumor environment permissive for infiltration by low-avidity CD8+ T cells. J. Immunol., 180, 3122-3131.
    • (2008) J. Immunol , vol.180 , pp. 3122-3131
    • Wong, S.B.1    Bos, R.2    Sherman, L.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.