Detecting precancerous lesions in the hamster cheek pouch using spectroscopic white-light optical coherence tomography to assess nuclear morphology via spectral oscillations

Journal of Biomedical Optics

Volumn 14, Issue 6, 2009, Pages

  Graf, Robert N ^a   Robles, Francisco E ^a   Chen, Xiaoxin ^b   Wax, Adam ^a  

^a Duke University   (United States)

^b NORTH CAROLINA CENTRAL UNIVERSITY   (United States)

Author keywords

Early cancer detection; Light scattering spectroscopy; Nuclear morphology; Optical coherence tomography; Spectroscopy

Indexed keywords

A-THERMAL; BASAL LAYER; CELL NUCLEUS; DEPTH RESOLUTION; DIAGNOSTIC METHODS; EARLY CANCER DETECTION; FREQUENCY DOMAIN OCT; HIGH BANDWIDTH; LIGHT SCATTERING SPECTROSCOPY; NUCLEAR MORPHOLOGY; POTENTIAL UTILITY; SPECTRAL OSCILLATIONS; SPECTROSCOPIC OPTICAL COHERENCE TOMOGRAPHIES; STATISTICALLY SIGNIFICANT DIFFERENCE; STRUCTURAL MEASUREMENTS; TISSUE SAMPLES; WHITE LIGHT;

MORPHOLOGY; TISSUE;

TOMOGRAPHY;

CRICETINAE;

ANIMAL; ARTICLE; CELL NUCLEUS; CELL TRANSFORMATION; CHEEK; DISEASE MODEL; EPITHELIUM; HAMSTER; LIGHT; MALE; METHODOLOGY; MOUTH TUMOR; OPTICAL COHERENCE TOMOGRAPHY; PATHOLOGY; PRECANCER; RADIATION SCATTERING; SYRIAN HAMSTER;

ANIMALS; CELL NUCLEUS; CELL TRANSFORMATION, NEOPLASTIC; CHEEK; CRICETINAE; DISEASE MODELS, ANIMAL; EPITHELIUM; LIGHT; MALE; MESOCRICETUS; MOUTH NEOPLASMS; PRECANCEROUS CONDITIONS; SCATTERING, RADIATION; TOMOGRAPHY, OPTICAL COHERENCE;

EID: 75749090648     PISSN: 10833668     EISSN: 15602281     Source Type: Journal    
DOI: 10.1117/1.3269680     Document Type: Article

References (23)

1. V. Kumar, A. K. Abbas, N. Fausto, S. L. Robbins, and R. S. Cotran, Robbins and Cotran Pathologic Basis of Disease, Elsevier/Saunders, Philadelphia (2005).
2. M. Panjehpour, B. F. Overholt, T. VoDinh, R. C. Haggitt, D. H. Edwards, and F. P. Buckley, "Endoscopic fluorescence detection of high-grade dysplasia in Barrett's esophagus," Gastroenterology 111(1), 93-101 (1996). (Pubitemid 26226888)
3. C. Kendall, N. Stone, N. Shepherd, K. Geboes, B. Warren, R. Bennett, and H. Barr, "Raman spectroscopy, a potential tool for the objective identification and classification of neoplasia in Barrett's oesophagus," J. Pathol. 200(5), 602-609 (2003). (Pubitemid 36987309)
4. P. R. Pfau, M. V. Sivak, A. Chak, M. Kinnard, R. C. K. Wong, G. A. Isenberg, J. A. Izatt, A. Rollins, and V. Westphal, "Criteria for the diagnosis of dysplasia by endoscopic optical coherence tomography," Gastrointest. Endosc. 58(2), 196-202 (2003). (Pubitemid 38220267)
5. L. T. Perelman, V. Backman, M. Wallace, G. Zonios, R. Manoharan, A. Nusrat, S. Shields, M. Seiler, C. Lima, T. Hamano, I. Itzkan, J. Van Dam, J. M. Crawford, and M. S. Feld, "Observation of periodic fine structure in reflectance from biological tissue: a new technique for measuring nuclear size distribution," Phys. Rev. Lett. 80(3), 627-630 (1998). (Pubitemid 128622229)
6. V. Backman, M. B. Wallace, L. T. Perelman, J. T. Arendt, R. Gurjar, M. G. Muller, Q. Zhang, G. Zonios, E. Kline, T. McGillican, S. Shapshay, T. Valdez, K. Badizadegan, J. M. Crawford, M. Fitzmaurice, S. Kabani, H. S. Levin, M. Seiler, R. R. Dasari, I. Itzkan, J. Van Dam, and M. S. Feld, "Detection of preinvasive cancer cells," Nature (London) 406(6791), 35-36 (2000). (Pubitemid 30460198)
7. M. B. Wallace, L. T. Perelman, V. Backman, J. M. Crawford, M. Fitzmaurice, M. Seiler, K. Badizadegan, S. J. Shields, I. Itzkan, R. R. Dasari, J. Van Dam, and M. S. Feld, "Endoscopic detection of dysplasia in patients with Barrett's esophagus using light-scattering spectroscopy," Gastroenterology 119(3), 677-682 (2000).
8. I. Georgakoudi, B. C. Jacobson, J. Van Dam, V. Backman, M. B. Wallace, M. G. Muller, Q. Zhang, K. Badizadegan, D. Sun, G. A. Thomas, L. T. Perelman, and M. S. Feld, "Fluorescence, reflectance, and light-scattering spectroscopy for evaluating dysplasia in patients with Barrett's esophagus," Gastroenterology 120(7), 1620-1629 (2001). (Pubitemid 32523481)
9. R. N. Graf and A. Wax, "Nuclear morphology measurements using Fourier domain low coherence interferometry," Opt. Express 13(12), 4693-4698 (2005). (Pubitemid 41029390)
10. A. Wax, C. H. Yang, and J. A. Izatt, "Fourier-domain low-coherence interferometry for light-scattering spectroscopy," Opt. Lett. 28(14), 1230-1232 (2003).
11. R. N. Graf, W. J. Brown, and A. Wax, "Parallel frequency-domain optical coherence tomography scatter-mode imaging of the hamster cheek pouch using a thermal light source," Opt. Lett. 33(12), 1285-1287 (2008).
12. A. Wax, C. H. Yang, R. R. Dasari, and M. S. Feld, "Measurement of angular distributions by use of low-coherence interferometry for light-scattering spectroscopy," Opt. Lett. 26(6), 322-324 (2001). (Pubitemid 33693233)
13. F. Robles, R. N. Graf, and A. Wax, "Dual window method for processing spectroscopic optical coherence tomography signals with simultaneously high spectral and temporal resolution," Opt. Express 17(8), 6799-6812 (2009).
14. R. N. Graf and A. Wax, "Temporal coherence and time-frequency distributions in spectroscopic optical coherence tomography," J. Opt. Soc. Am. A 24(8), 2186-2195 (2007). (Pubitemid 351193462)
15. A. M. Zysk, S. G. Adie, J. J. Armstrong, M. S. Leigh, A. Paduch, D. D. Sampson, F. T. Nguyen, and S. A. Boppart, "Needle-based refractive index measurement using low-coherence interferometry," Opt. Lett. 32(4), 385-387 (2007). (Pubitemid 46354031)
16. A. M. Zysk, D. L. Marks, D. Y. Liu, and S. A. Boppart, "Needlebased reflection refractometry of scattering samples using coherencegated detection," Opt. Express 15(8), 4787-4794 (2007). (Pubitemid 46609023)
17. J. M. Schmitt and G. Kumar, "Turbulent nature of refractive-index variations in biological tissue," Opt. Lett. 21(16), 1310-1312 (1996). (Pubitemid 126569103)
18. V. V. Tuchin, Tissue Optics: Light Scattering Methods and Instruments for Medical Diagnosis, SPIE Press, Bellingham, WA (2000).
19. A. Wax, C. H. Yang, V. Backman, K. Badizadegan, C. W. Boone, R. R. Dasari, and M. S. Feld, "Cellular organization and substructure measured using angle-resolved low-coherence interferometry," Biophys. J. 82(4), 2256-2264 (2002). (Pubitemid 34280836)
20. F. H. White and K. Gohari, "Cellular and nuclear volumetric alterations during differentiation of normal hamster-cheek pouch epithelium," Arch. Dermatol. Res. 273(3-4), 307-318 (1982). (Pubitemid 12040849)
21. Y. L. Kim, Y. Liu, R. K. Wali, H. K. Roy, and V. Backman, "Lowcoherent backscattering spectroscopy for tissue characterization," Appl. Opt. 44(3), 366-377 (2005). (Pubitemid 40163310)
22. H. K. Roy, Y. L. Kim, Y. Liu, R. K. Wali, M. J. Goldberg, V. Turzhitsky, J. Horwitz, and V. Backman, "Risk stratification of colon carcinogenesis through enhanced backscattering spectroscopy analysis of the uninvolved colonic mucosa," Clin. Cancer Res. 12(3), 961-968 (2006). (Pubitemid 43259879)
23. Y. Liu, R. E. Brand, V. Turzhitsky, Y. L. Kim, H. K. Roy, N. Hasabou, C. Sturgis, D. Shah, C. Hall, and V. Backman, "Optical markers in duodenal mucosa predict the presence of pancreatic cancer," Clin. Cancer Res. 13(15), 4392-4399 (2007). (Pubitemid 47219705)