Severe meningoencephalitis due to late reactivation of varicella-zoster virus in an immunocompetent child

Journal of Child Neurology

Volumn 25, Issue 1, 2010, Pages 87-90

  Spiegel, Ronen ^a,b   Miron, Dan ^a,b   Lumelsky, Dmitry ^a   Horovitz, Yoseph ^a,b  

^a HAEMEK MEDICAL CENTER   (Israel)

^b TECHNION ISRAEL INSTITUTE OF TECHNOLOGY   (Israel)

Author keywords

Cerebral arteritis; Meningoencephalitis; Varicella Zoster virus

Indexed keywords

ACICLOVIR; METHYLPREDNISOLONE; VIRUS DNA;

ADOLESCENT; ARTICLE; BRAIN VASCULITIS; CASE REPORT; CEREBROSPINAL FLUID; CHICKENPOX; DISEASE SEVERITY; DRUG MEGADOSE; FEMALE; HERPES ZOSTER; HERPES ZOSTER ENCEPHALITIS; HUMAN; IMMUNOCOMPETENCE; MENINGOENCEPHALITIS; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; VARICELLA ZOSTER VIRUS; VIRUS REACTIVATION;

ACYCLOVIR; ADOLESCENT; ANTIVIRAL AGENTS; BRAIN; CHICKENPOX; DIAGNOSIS, DIFFERENTIAL; DNA, VIRAL; ENCEPHALITIS, VARICELLA ZOSTER; FEMALE; FOLLOW-UP STUDIES; HERPES ZOSTER; HERPESVIRUS 3, HUMAN; HUMANS; IMMUNOCOMPETENCE; MENINGOENCEPHALITIS; METHYLPREDNISOLONE; TIME FACTORS; TREATMENT OUTCOME; VASCULITIS, CENTRAL NERVOUS SYSTEM; VIRUS ACTIVATION;

EID: 75649136219     PISSN: 08830738     EISSN: 17088283     Source Type: Journal    
DOI: 10.1177/0883073809336296     Document Type: Article

References (12)

1. Gilden DH, Kleinschmidt-DeMasters BK, LaGuardia JJ, et al. Neurologic complications of the reactivation of varicella-zoster virus. New Eng J Med. 2000 ; 342 (14). 635-645.
2. Kleinschmidt-DeMasters BK, Gilden DH Varicella-Zoster virus infections of the nervous system: clinical and pathologic correlates. Arch Pathol Lab Med. 2001 ; 125 (6). 770-780.
3. Chiappini E., Calabri G., Galli L., et al. Varicella-zoster virus acquired at 4 months of age reactivates at 24 months and causes encephalitis. J Pediatr. 2002 ; 140 (2). 250-251.
4. Jhaveri R., Sankar R., Yazdani S., Cherry JD Varicella-zoster virus: an overlooked cause of aseptic meningitis. Pediatr Infect Dis J. 2003 ; 22 (1). 96-97.
5. Chiappini E., de Martino M., Jhaveri R. Varicella-zoster virus reactivation in the central nervous system. Pediatr Infect Dis J. 2004 ; 23 (2). 185-186.
6. Nagel MA, Cohrs RJ, Mahalingam R., et al. The varicella zoster virus vasculopathies: clinical, CSF, imaging, and virologic features. Neurology. 2008 ; 70 (11). 853-860.
7. Steiner I., Kennedy PGE, Pachner AR The neurotropic herpes viruses: herpes simplex and varicella-zoster. Lancet Neurol. 2007 ; 6 (11). 1015-1028.
8. Zhang SY, Jouanguy E., Ugolini S., et al. TLR3 deficiency in patients with herpes simplex encephalitis. Science. 2007 ; 317 (5844). 1522-1527.
9. Casrouge A., Zhang SY, Eidenschenk C., et al. Herpes simplex virus encephalitis in human UNC-93B deficiency. Science. 2006 ; 314 (5797). 308-312.
10. Leahy TR, Webb DW, Hoey H., Butler KM Varicella zoster virus associated acute aseptic meningitis without exanthem in an immunocompetent 14-year-old boy. Pediatr Infect Dis J. 2008 ; 27 (4). 362-363.
11. Melanson M., Chalk C., Georgevich L., et al. Varicella-zoster virus DNA in CSF and arteries in delayed contralateral hemiplegia: evidence for viral invasion of cerebral arteries. Neurology. 1996 ; 47 (2). 569-570.
12. Hausler M., Schaade L., Kemeny S., et al. Encephalitis related to primary varicella-zoster virus infection in immunocompetent children. J Neurol Sci. 2002 ; 195 (2). 111-116.